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The map label for this gene is ftsW [H]

Identifier: 83592287

GI number: 83592287

Start: 1134750

End: 1135928

Strand: Reverse

Name: ftsW [H]

Synonym: Rru_A0951

Alternate gene names: 83592287

Gene position: 1135928-1134750 (Counterclockwise)

Preceding gene: 83592288

Following gene: 83592286

Centisome position: 26.1

GC content: 66.84

Gene sequence:

>1179_bases
ATGACCATGCGCGTCGTCACCGCCCCGGCCGAACCGCCCCAGGGGGCAAGCCATGTCGCCCCCTCGTTCACGCGGATGGA
CACCAGCGTTCTTGGGCGCTGGTGGTGGACGGTCGACCGCCCGATGCTGGGCGCCGTCGCGCTGCTGATCGCCGCCGGGG
TGTTCCTGATCCTGGCCGCCGGTCCGCCGGCCGCCGGTCGGATCGGCGCGCAGACCTATCACTTCGTCCAGCGCCAGTTC
CTGTTCGTGCCGGTGGCCGGCGTGCTGGTGATCGCCGTTTCCCTGCTGCCGGTGCTGTGGGTGCGGCGCATCGCCGTTTT
GCTGTTCGCCCTGTTCATGGTGCTTTTGCTCGGCACGCTGTTTGTCAGCAGCGACATCAAGGGCGCCTCGCGCTGGATCG
CCATCGGTCCCTTCGCCCTGCAGCCCTCGGAATTCGTCAAGCCGACCTTCGCCGTGGTCACCGCCTGGATGTTCGCCTCG
GCCCGCACCCAGGACCGTTTCCCCGGCAATCTGATCGCCATGCTTCTGATGGCGGTGGTCGGCGCCCTGCTCGTTGCCCA
GCCCGATTTCGGCATGACCATGGTCGTCGCCTGCGTCTGGGGAACCCAGTTCTTCCTGGCCGGGCTGTCGCTGGTCTGGG
TGGTGCTGTTGGCCGCCGTCGGCATGATCGGCGCCGTCATCGCCTATTTCGCCCTGCCCCATGTGCAAAGCCGCGTCGAT
CGCTTCCTTGATCCGGCCAGCGGCGACCAGTATCAGATCCGCCAGTCGATGAAGGCCTTCATGGAGGGCGGGTTGTTCGG
GCGCGGGCCCGGCGAAGGCCGGGTGAAGGAATTCCTCCCCGACGCCCATACCGACTTCATCTTCGCCGTGGCCGGCGAGG
AGTTCGGGCTGTTTTTGTGCCTGACCATCGTCGCCCTCTTCGCCTTTCTCATCATCCGCTCGGCCATCCGCCTGCGCCGC
GAACAGAACCTGTTCGTGCTGATCGCCGCCGGCGGCCTGCTGACCCAGCTTGGCTTGCAAGCCTTGATCAACATGGCCTC
CAGTCTCAGCCTGATCCCGACCAAGGGCATGACCTTGCCGTTCATCAGCTATGGCGGGTCGTCGCTGCTGTCGACCGCCG
TGGCGATGGGCATGGTTCTGGCCCTGACCCGGCGGCGAGCCCATGGGGAGCGCACGTGA

Upstream 100 bases:

>100_bases
GGGATCAGTTCTCCAGCTTCGAGCATCGCGGCGACATCTTCCGCGAACTCGTCGCCGATCTCGCCCATACCCGGGCCGCC
GCCAAGCCGGGGGGCCGCCG

Downstream 100 bases:

>100_bases
TGAACGCCTCGATGCCCCGCGACGGCGCCCTGCTGGTCAATGCGCCGCTCCATATCGCCCTGGCGGCCGGCGGAACCGGC
GGCCATGTCTTCCCGGCCGA

Product: cell cycle protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MTMRVVTAPAEPPQGASHVAPSFTRMDTSVLGRWWWTVDRPMLGAVALLIAAGVFLILAAGPPAAGRIGAQTYHFVQRQF
LFVPVAGVLVIAVSLLPVLWVRRIAVLLFALFMVLLLGTLFVSSDIKGASRWIAIGPFALQPSEFVKPTFAVVTAWMFAS
ARTQDRFPGNLIAMLLMAVVGALLVAQPDFGMTMVVACVWGTQFFLAGLSLVWVVLLAAVGMIGAVIAYFALPHVQSRVD
RFLDPASGDQYQIRQSMKAFMEGGLFGRGPGEGRVKEFLPDAHTDFIFAVAGEEFGLFLCLTIVALFAFLIIRSAIRLRR
EQNLFVLIAAGGLLTQLGLQALINMASSLSLIPTKGMTLPFISYGGSSLLSTAVAMGMVLALTRRRAHGERT

Sequences:

>Translated_392_residues
MTMRVVTAPAEPPQGASHVAPSFTRMDTSVLGRWWWTVDRPMLGAVALLIAAGVFLILAAGPPAAGRIGAQTYHFVQRQF
LFVPVAGVLVIAVSLLPVLWVRRIAVLLFALFMVLLLGTLFVSSDIKGASRWIAIGPFALQPSEFVKPTFAVVTAWMFAS
ARTQDRFPGNLIAMLLMAVVGALLVAQPDFGMTMVVACVWGTQFFLAGLSLVWVVLLAAVGMIGAVIAYFALPHVQSRVD
RFLDPASGDQYQIRQSMKAFMEGGLFGRGPGEGRVKEFLPDAHTDFIFAVAGEEFGLFLCLTIVALFAFLIIRSAIRLRR
EQNLFVLIAAGGLLTQLGLQALINMASSLSLIPTKGMTLPFISYGGSSLLSTAVAMGMVLALTRRRAHGERT
>Mature_391_residues
TMRVVTAPAEPPQGASHVAPSFTRMDTSVLGRWWWTVDRPMLGAVALLIAAGVFLILAAGPPAAGRIGAQTYHFVQRQFL
FVPVAGVLVIAVSLLPVLWVRRIAVLLFALFMVLLLGTLFVSSDIKGASRWIAIGPFALQPSEFVKPTFAVVTAWMFASA
RTQDRFPGNLIAMLLMAVVGALLVAQPDFGMTMVVACVWGTQFFLAGLSLVWVVLLAAVGMIGAVIAYFALPHVQSRVDR
FLDPASGDQYQIRQSMKAFMEGGLFGRGPGEGRVKEFLPDAHTDFIFAVAGEEFGLFLCLTIVALFAFLIIRSAIRLRRE
QNLFVLIAAGGLLTQLGLQALINMASSLSLIPTKGMTLPFISYGGSSLLSTAVAMGMVLALTRRRAHGERT

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=355, Percent_Identity=34.6478873239437, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1786853, Length=330, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=9e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 42272; Mature: 42141

Theoretical pI: Translated: 10.93; Mature: 10.93

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS00063 ALDOKETO_REDUCTASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TMRVVTAPAEPPQGASHVAPSFTRMDTSVLGRWWWTVDRPMLGAVALLIAAGVFLILAA
CEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
GPPAAGRIGAQTYHFVQRQFLFVPVAGVLVIAVSLLPVLWVRRIAVLLFALFMVLLLGTL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVSSDIKGASRWIAIGPFALQPSEFVKPTFAVVTAWMFASARTQDRFPGNLIAMLLMAVV
HHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
GALLVAQPDFGMTMVVACVWGTQFFLAGLSLVWVVLLAAVGMIGAVIAYFALPHVQSRVD
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFLDPASGDQYQIRQSMKAFMEGGLFGRGPGEGRVKEFLPDAHTDFIFAVAGEEFGLFLC
HHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCEEEEECCCCHHHHHH
LTIVALFAFLIIRSAIRLRREQNLFVLIAAGGLLTQLGLQALINMASSLSLIPTKGMTLP
HHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
FISYGGSSLLSTAVAMGMVLALTRRRAHGERT
CHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]