Click here to switch to the map view.

The map label for this gene is murG

Identifier: 83592286

GI number: 83592286

Start: 1133587

End: 1134750

Strand: Reverse

Name: murG

Synonym: Rru_A0950

Alternate gene names: 83592286

Gene position: 1134750-1133587 (Counterclockwise)

Preceding gene: 83592287

Following gene: 83592285

Centisome position: 26.07

GC content: 72.42

Gene sequence:

>1164_bases
ATGAACGCCTCGATGCCCCGCGACGGCGCCCTGCTGGTCAATGCGCCGCTCCATATCGCCCTGGCGGCCGGCGGAACCGG
CGGCCATGTCTTCCCGGCCGAGGCCCTGGCCGGGGAATTGATCCGCCGCGGCCATAAGCTGACGCTGATCACCGACAAGC
GCGGCCATGTCTATGGCGGCACCCTGGGTCTGCTCGACACCAAGCGCATCCTGGCCGGTGGCGTCGCCGGGCGGGGCGTG
ATCGGCCGCCTGCGCGGCATGATCGAACTGGCGATGGGCAGCCTTCAAGCCTATGGCCTGCTGCGCCGGCTGCGCCCCGA
TGTCGTCGTCGGCTTTGGCGGCTATGCCTCGGTGCCGACCATGCTGGCGGCGATCCGCCTGAAACTGCCCACCGTCGTCC
ACGAGCAAAACGCCGTGCCCGGCCGGGCCAACCGCCTGCTCGCCGCCCGCGTCAGCCGCTATGCGGTGTCCTTCGCCCGG
GCCGAGCGGCCGCGCGGCGCCCGGCCGGTGGTCGTCGGCATGCCGGTGCGGCCCTCGGTTCTGGCCTTGCGCGGCGAAGG
CTATGACGCGCCGCGCCCGGGCCTGGACTTCCGCCTGCTGATCACCGGCGGCAGCCAGGGCGCCCGGGTCTTCGCCACCC
TGGTTCCCCAGGCCCTGGCCCTGTTGTCGCCCGCCCACCGCGCCCGGTTGCGCGTGACCCAGCAATGCCGGCCCGAGGAC
ATCGAGGCGGTGCGCGCGACCTATGAGGCGCAAGGCATCGACGCCCTGCTCTCGGCCTTCTTCTCCGATCTGCCCGAACG
CCTGCGCGACGCCCATCTGGTGATTTGCCGCTCGGGCGCCTCGACGGTCGGCGAACTGGCCGCCCTGGGACGCCCGGCGA
TCCTGGTGCCCTTTCCCCATGCCATCGACGACCACCAGACCGCCAATGCCCGCGGCCTGGACGAGGTTGGCGGCGGCTGG
CTGATGCCCCAAGCGGCCCTGACCCCGCAAGCCCTGGCCGAACGCCTGGGCGAATTGATGGACGATCCCGACGTGCTGGT
CCGCGCCGCGCAGTGCGCCCGGGGCGCGGGCGTGCCCGATGCCGCGGTGCGGCTGGCCGATCTGGTGAGCGCGACCGCAG
ACCATCGGGTGCCCGAGATGCCCCCCAAGGAGATTTCCGCATGA

Upstream 100 bases:

>100_bases
CGTTCATCAGCTATGGCGGGTCGTCGCTGCTGTCGACCGCCGTGGCGATGGGCATGGTTCTGGCCCTGACCCGGCGGCGA
GCCCATGGGGAGCGCACGTG

Downstream 100 bases:

>100_bases
GAGCCCTGCCCCTCGATATCGGCCCCTTGCACTTCGTGGGCATCGGCGGCATCGGCATGAGCGGCATCGCCGAGGTCCTG
CATAACCTGGGCTACCGGGT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MNASMPRDGALLVNAPLHIALAAGGTGGHVFPAEALAGELIRRGHKLTLITDKRGHVYGGTLGLLDTKRILAGGVAGRGV
IGRLRGMIELAMGSLQAYGLLRRLRPDVVVGFGGYASVPTMLAAIRLKLPTVVHEQNAVPGRANRLLAARVSRYAVSFAR
AERPRGARPVVVGMPVRPSVLALRGEGYDAPRPGLDFRLLITGGSQGARVFATLVPQALALLSPAHRARLRVTQQCRPED
IEAVRATYEAQGIDALLSAFFSDLPERLRDAHLVICRSGASTVGELAALGRPAILVPFPHAIDDHQTANARGLDEVGGGW
LMPQAALTPQALAERLGELMDDPDVLVRAAQCARGAGVPDAAVRLADLVSATADHRVPEMPPKEISA

Sequences:

>Translated_387_residues
MNASMPRDGALLVNAPLHIALAAGGTGGHVFPAEALAGELIRRGHKLTLITDKRGHVYGGTLGLLDTKRILAGGVAGRGV
IGRLRGMIELAMGSLQAYGLLRRLRPDVVVGFGGYASVPTMLAAIRLKLPTVVHEQNAVPGRANRLLAARVSRYAVSFAR
AERPRGARPVVVGMPVRPSVLALRGEGYDAPRPGLDFRLLITGGSQGARVFATLVPQALALLSPAHRARLRVTQQCRPED
IEAVRATYEAQGIDALLSAFFSDLPERLRDAHLVICRSGASTVGELAALGRPAILVPFPHAIDDHQTANARGLDEVGGGW
LMPQAALTPQALAERLGELMDDPDVLVRAAQCARGAGVPDAAVRLADLVSATADHRVPEMPPKEISA
>Mature_387_residues
MNASMPRDGALLVNAPLHIALAAGGTGGHVFPAEALAGELIRRGHKLTLITDKRGHVYGGTLGLLDTKRILAGGVAGRGV
IGRLRGMIELAMGSLQAYGLLRRLRPDVVVGFGGYASVPTMLAAIRLKLPTVVHEQNAVPGRANRLLAARVSRYAVSFAR
AERPRGARPVVVGMPVRPSVLALRGEGYDAPRPGLDFRLLITGGSQGARVFATLVPQALALLSPAHRARLRVTQQCRPED
IEAVRATYEAQGIDALLSAFFSDLPERLRDAHLVICRSGASTVGELAALGRPAILVPFPHAIDDHQTANARGLDEVGGGW
LMPQAALTPQALAERLGELMDDPDVLVRAAQCARGAGVPDAAVRLADLVSATADHRVPEMPPKEISA

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=360, Percent_Identity=35, Blast_Score=159, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_RHORT (Q2RVU4)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_426038.1
- ProteinModelPortal:   Q2RVU4
- SMR:   Q2RVU4
- STRING:   Q2RVU4
- GeneID:   3833623
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A0950
- NMPDR:   fig|1085.1.peg.3422
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   Q2RVU4
- ProtClustDB:   PRK00726
- BioCyc:   RRUB269796:RRU_A0950-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 40805; Mature: 40805

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNASMPRDGALLVNAPLHIALAAGGTGGHVFPAEALAGELIRRGHKLTLITDKRGHVYGG
CCCCCCCCCEEEEECCEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCEEECC
TLGLLDTKRILAGGVAGRGVIGRLRGMIELAMGSLQAYGLLRRLRPDVVVGFGGYASVPT
EEECHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHH
MLAAIRLKLPTVVHEQNAVPGRANRLLAARVSRYAVSFARAERPRGARPVVVGMPVRPSV
HHHHHHHHCCHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCE
LALRGEGYDAPRPGLDFRLLITGGSQGARVFATLVPQALALLSPAHRARLRVTQQCRPED
EEEECCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHH
IEAVRATYEAQGIDALLSAFFSDLPERLRDAHLVICRSGASTVGELAALGRPAILVPFPH
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCEEEEECCC
AIDDHQTANARGLDEVGGGWLMPQAALTPQALAERLGELMDDPDVLVRAAQCARGAGVPD
CCCCCCCCCCCCCHHCCCCEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCH
AAVRLADLVSATADHRVPEMPPKEISA
HHHHHHHHHHHHHHCCCCCCCCHHCCC
>Mature Secondary Structure
MNASMPRDGALLVNAPLHIALAAGGTGGHVFPAEALAGELIRRGHKLTLITDKRGHVYGG
CCCCCCCCCEEEEECCEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCEEECC
TLGLLDTKRILAGGVAGRGVIGRLRGMIELAMGSLQAYGLLRRLRPDVVVGFGGYASVPT
EEECHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHH
MLAAIRLKLPTVVHEQNAVPGRANRLLAARVSRYAVSFARAERPRGARPVVVGMPVRPSV
HHHHHHHHCCHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCE
LALRGEGYDAPRPGLDFRLLITGGSQGARVFATLVPQALALLSPAHRARLRVTQQCRPED
EEEECCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHH
IEAVRATYEAQGIDALLSAFFSDLPERLRDAHLVICRSGASTVGELAALGRPAILVPFPH
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCEEEEECCC
AIDDHQTANARGLDEVGGGWLMPQAALTPQALAERLGELMDDPDVLVRAAQCARGAGVPD
CCCCCCCCCCCCCHHCCCCEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCH
AAVRLADLVSATADHRVPEMPPKEISA
HHHHHHHHHHHHHHCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA