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The map label for this gene is hisS

Identifier: 83592087

GI number: 83592087

Start: 876421

End: 877668

Strand: Direct

Name: hisS

Synonym: Rru_A0748

Alternate gene names: 83592087

Gene position: 876421-877668 (Clockwise)

Preceding gene: 83592086

Following gene: 83592088

Centisome position: 20.13

GC content: 67.71

Gene sequence:

>1248_bases
GTGGCCGCCTTGCAGCCTGTTCGAGGGACGCACGACTACCTTCCCGATGAAGCCCGTTCGCACCGCCATGTGGAGGAAAC
CGCCCGCACGGTGGCCGAGCGTTTCGGCTTCGGCGAGATCATCACCCCGATCTTCGAGTTCACCGATGTCTTCGCCCGCA
CCCTGGGCGATACCTCCGATGTCGTGACCAAGGAGATGTACACCTTCACCGATCGCTCGGGCGACAGCCTGACCCTGCGG
CCGGAAAACACCGCCGGGGTGGCTCGCGCCTTCATTTCGGGCGGTCTGGCGCAAAATGTGCCGGTGAAGCTGTTCTATCG
CGGGCCGATGTTCCGCCACGAGCGCCCGCAGAAGGGCCGCCTGCGCCAGTTCCACCAGGTCGGCGTCGAGTTGATCGGCG
CCGAGAACCCCTTGGCCGATGTCGAGGTCATCGCCCTGGGCAGCCAGTTGCTGGGCGCCCTGGGCGTTGGCGGGCGCACC
ATCTTGCATCTCAACAGCCTGGGCGATCCCGAAAGCCGCGAGGCCTATCGGGCGGCGCTGGTGTCTTATCTGTCGGGGCA
CCGCGACAGCCTGTCGCGCGACAGCCTGGAGCGCCTGGAGCGCAACCCGCTGCGCGTGCTTGATTCCAAGGACGAGGGCG
ACCGCGCCGTGGTCGCCGGGGCGCCGCGCCTGATCGACCACCTGAACGAGGCCAGCCGGGCTTTCTTCGCCGGGGTGACC
GGCGGCTTGGAAGCCCTGGGGATCCCCTTCGAGATCGATCCCTTGCTGGTGCGCGGTCTGGACTATTACGGCCATACCGC
CTTTGAATTCGTCACCACCGATCTGGGGGCCCAGGGCACGGTGATGGCCGGCGGGCGCTATGACGGTCTGATCCGCCAGA
TGGGCGGATCGCAGACGCCGGGCGTGGGCTGGGCGGCGGGCGTCGAGCGGCTGTCCATGCTGATGGCCGCCGATCGGGTG
GGCGCGCCGCGACCGCTGGCGATGATCCCCGCCGGTCCCGATGACGAGGTCGAGGCGCTGAAGCTGGCCCATGCCCTGCG
TCAGGGCGGGCTGTTCGTCGATTTCGGCTATTCGGGCAATCTCGGCAAGCGCATGAAGCGGGCCAACCGCATCAACGCCC
GGGCCGCCATCATCCTTGGCGGCGAGGAGCGCGCCAATGGAACGGTCGTCGTGCGCGATCTTGACAGCGGCGAGCAGGAA
ACCATCGGCCTTGCTGTGCTGGAGGAGTTCCTGGCCCGGTTCCTCTAG

Upstream 100 bases:

>100_bases
CGGGGCCGCCTTTGCGTTCCTAGACAGCGGCCCCTTGGGGATGGTATCGCAGAGCGGCCAACCGGGCCTTCCTGGGCCCC
GTGATATGAGGACGTTGACC

Downstream 100 bases:

>100_bases
CTTATCGGAGGGGAGAGCGGGTGGCGCAGGAGCGGACGGCGGGATGCGGGGTGGACGGCTACGTGATGGTGGGGGTGAAC
CACCAGACCACGCCGATGGC

Product: histidyl-tRNA synthetase

Products: NA

Alternate protein names: Histidine--tRNA ligase; HisRS

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MAALQPVRGTHDYLPDEARSHRHVEETARTVAERFGFGEIITPIFEFTDVFARTLGDTSDVVTKEMYTFTDRSGDSLTLR
PENTAGVARAFISGGLAQNVPVKLFYRGPMFRHERPQKGRLRQFHQVGVELIGAENPLADVEVIALGSQLLGALGVGGRT
ILHLNSLGDPESREAYRAALVSYLSGHRDSLSRDSLERLERNPLRVLDSKDEGDRAVVAGAPRLIDHLNEASRAFFAGVT
GGLEALGIPFEIDPLLVRGLDYYGHTAFEFVTTDLGAQGTVMAGGRYDGLIRQMGGSQTPGVGWAAGVERLSMLMAADRV
GAPRPLAMIPAGPDDEVEALKLAHALRQGGLFVDFGYSGNLGKRMKRANRINARAAIILGGEERANGTVVVRDLDSGEQE
TIGLAVLEEFLARFL

Sequences:

>Translated_415_residues
MAALQPVRGTHDYLPDEARSHRHVEETARTVAERFGFGEIITPIFEFTDVFARTLGDTSDVVTKEMYTFTDRSGDSLTLR
PENTAGVARAFISGGLAQNVPVKLFYRGPMFRHERPQKGRLRQFHQVGVELIGAENPLADVEVIALGSQLLGALGVGGRT
ILHLNSLGDPESREAYRAALVSYLSGHRDSLSRDSLERLERNPLRVLDSKDEGDRAVVAGAPRLIDHLNEASRAFFAGVT
GGLEALGIPFEIDPLLVRGLDYYGHTAFEFVTTDLGAQGTVMAGGRYDGLIRQMGGSQTPGVGWAAGVERLSMLMAADRV
GAPRPLAMIPAGPDDEVEALKLAHALRQGGLFVDFGYSGNLGKRMKRANRINARAAIILGGEERANGTVVVRDLDSGEQE
TIGLAVLEEFLARFL
>Mature_414_residues
AALQPVRGTHDYLPDEARSHRHVEETARTVAERFGFGEIITPIFEFTDVFARTLGDTSDVVTKEMYTFTDRSGDSLTLRP
ENTAGVARAFISGGLAQNVPVKLFYRGPMFRHERPQKGRLRQFHQVGVELIGAENPLADVEVIALGSQLLGALGVGGRTI
LHLNSLGDPESREAYRAALVSYLSGHRDSLSRDSLERLERNPLRVLDSKDEGDRAVVAGAPRLIDHLNEASRAFFAGVTG
GLEALGIPFEIDPLLVRGLDYYGHTAFEFVTTDLGAQGTVMAGGRYDGLIRQMGGSQTPGVGWAAGVERLSMLMAADRVG
APRPLAMIPAGPDDEVEALKLAHALRQGGLFVDFGYSGNLGKRMKRANRINARAAIILGGEERANGTVVVRDLDSGEQET
IGLAVLEEFLARFL

Specific function: Unknown

COG id: COG0124

COG function: function code J; Histidyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Escherichia coli, GI1788861, Length=407, Percent_Identity=48.1572481572482, Blast_Score=368, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24643061, Length=467, Percent_Identity=25.6959314775161, Blast_Score=92, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYH_RHORT (Q2RWE3)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_425839.1
- ProteinModelPortal:   Q2RWE3
- SMR:   Q2RWE3
- STRING:   Q2RWE3
- GeneID:   3834157
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A0748
- NMPDR:   fig|1085.1.peg.1597
- eggNOG:   COG0124
- HOGENOM:   HBG616575
- OMA:   VFEWVTT
- PhylomeDB:   Q2RWE3
- ProtClustDB:   PRK00037
- BioCyc:   RRUB269796:RRU_A0748-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00127
- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR015807
- InterPro:   IPR004516
- Gene3D:   G3DSA:3.40.50.800
- PANTHER:   PTHR11476
- PIRSF:   PIRSF001549
- TIGRFAMs:   TIGR00442

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b; SSF52954 Anticodon_bd

EC number: =6.1.1.21

Molecular weight: Translated: 44963; Mature: 44831

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALQPVRGTHDYLPDEARSHRHVEETARTVAERFGFGEIITPIFEFTDVFARTLGDTSD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHH
VVTKEMYTFTDRSGDSLTLRPENTAGVARAFISGGLAQNVPVKLFYRGPMFRHERPQKGR
HHHHHHHHEECCCCCEEEECCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCHHH
LRQFHQVGVELIGAENPLADVEVIALGSQLLGALGVGGRTILHLNSLGDPESREAYRAAL
HHHHHHHCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHH
VSYLSGHRDSLSRDSLERLERNPLRVLDSKDEGDRAVVAGAPRLIDHLNEASRAFFAGVT
HHHHHCCCCCCCHHHHHHHHCCCCEEECCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHC
GGLEALGIPFEIDPLLVRGLDYYGHTAFEFVTTDLGAQGTVMAGGRYDGLIRQMGGSQTP
CCHHHCCCCEECCHHHHHCCHHCCCHHHHHHHHCCCCCCEEEECCCHHHHHHHCCCCCCC
GVGWAAGVERLSMLMAADRVGAPRPLAMIPAGPDDEVEALKLAHALRQGGLFVDFGYSGN
CCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCEEEEECCCCC
LGKRMKRANRINARAAIILGGEERANGTVVVRDLDSGEQETIGLAVLEEFLARFL
HHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
AALQPVRGTHDYLPDEARSHRHVEETARTVAERFGFGEIITPIFEFTDVFARTLGDTSD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHH
VVTKEMYTFTDRSGDSLTLRPENTAGVARAFISGGLAQNVPVKLFYRGPMFRHERPQKGR
HHHHHHHHEECCCCCEEEECCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCHHH
LRQFHQVGVELIGAENPLADVEVIALGSQLLGALGVGGRTILHLNSLGDPESREAYRAAL
HHHHHHHCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHH
VSYLSGHRDSLSRDSLERLERNPLRVLDSKDEGDRAVVAGAPRLIDHLNEASRAFFAGVT
HHHHHCCCCCCCHHHHHHHHCCCCEEECCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHC
GGLEALGIPFEIDPLLVRGLDYYGHTAFEFVTTDLGAQGTVMAGGRYDGLIRQMGGSQTP
CCHHHCCCCEECCHHHHHCCHHCCCHHHHHHHHCCCCCCEEEECCCHHHHHHHCCCCCCC
GVGWAAGVERLSMLMAADRVGAPRPLAMIPAGPDDEVEALKLAHALRQGGLFVDFGYSGN
CCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCEEEEECCCCC
LGKRMKRANRINARAAIILGGEERANGTVVVRDLDSGEQETIGLAVLEEFLARFL
HHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA