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The map label for this gene is hyfC [H]

Identifier: 83591657

GI number: 83591657

Start: 387380

End: 388282

Strand: Direct

Name: hyfC [H]

Synonym: Rru_A0317

Alternate gene names: 83591657

Gene position: 387380-388282 (Clockwise)

Preceding gene: 83591656

Following gene: 83591658

Centisome position: 8.9

GC content: 61.13

Gene sequence:

>903_bases
GTGGAAAACGTCGGACTCGCGATCTTCAACGTTCTTTTGGTGGTCTGCGCCGCGCCGCTGCTTGATGGCGTTCTGCGTCA
GGTCAAGGCCCGCATCCATTCCCGCCAGGGGCCGCCGATTCTGCAGACCTACTTCGATCTGGCCAAGCTGCTGGTCAAGG
AGGACCAGCGCGGCGTCAATCAGCTGTTGTTCGCCTGGGCCCCGGTGGTCTGCATGGCCTCGGTCATCCTCTCGGCGCTG
TTCGTGCCGATGGCCGGTCTCTCGCCGCTGGGCTTCTCGGGCGACGCCATCGTCTTCTTGTATGTGCTGACCATGGCGCC
GCTGTGCATGTGCTTAGGCGGCATGGCCTCGGGCAGCCCCTATGCCTATGCCGGGGCCAACCGCGAGATCATGACCCTAA
TGGCGGTCGAGCCGGTGGTGGCGATCTGCCTGATCACCTCGGGGATCCGCGCCCATTCGCTCAATCTCGCCGATTGCGTC
AACGCCTATGCCGCCGGCGCCCCGGCGCTGTCGATGATCATCGCCACCATCGCCTTCTTCCTGATCCTGCCCGCCGAGCT
GTCGAAGGTTCCCTTCGATCAGGCGGAGGCCGAGACCGAGATCATGGAAGGGCCGCTGATCGAATATTCGGGCCGCAAGC
TGGCGCTGTTCAAATGGTCGTTTTACGCCAAGCAAATCGTGCTGATCACCCTGTTCGTCGAATGGTTCCTGCCGTGGCCG
CACATGAATTTCGTGCCGCTCGACATCCTTGCCACCCTGATCAAGGTCGTGATCGTCGCCGTTATTATTGAAGTCATCGC
CCAGATCTTTCCCCGTTTCAAAATCCATCAAAGCATCCGCTATTTCTACGCGGTGGTCGCTTTCTCGGTCGGGGGTCTGG
TCTTGGCGGTCATGGGTCTGTAG

Upstream 100 bases:

>100_bases
CCGAACGCGTGCTCACGGTCGATACGAAAAGCAAAGCCATCCGCACCTACACCGAAAAAGACCTGCTGGCGCTGACCCGT
CGGGCGGGGGGCAGGTAATC

Downstream 100 bases:

>100_bases
GGGGCATCATGCTGAGCAAAATCAAAGAAGCCCTGATCTGCCTGCGGGCCGGGCGCGTCACCCTTCCTTATCCCTTCGTG
CCGCTGAAGGCCCCGCCGCG

Product: respiratory-chain NADH dehydrogenase, subunit 1

Products: H2; oxidized ferredoxin [C]

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MENVGLAIFNVLLVVCAAPLLDGVLRQVKARIHSRQGPPILQTYFDLAKLLVKEDQRGVNQLLFAWAPVVCMASVILSAL
FVPMAGLSPLGFSGDAIVFLYVLTMAPLCMCLGGMASGSPYAYAGANREIMTLMAVEPVVAICLITSGIRAHSLNLADCV
NAYAAGAPALSMIIATIAFFLILPAELSKVPFDQAEAETEIMEGPLIEYSGRKLALFKWSFYAKQIVLITLFVEWFLPWP
HMNFVPLDILATLIKVVIVAVIIEVIAQIFPRFKIHQSIRYFYAVVAFSVGGLVLAVMGL

Sequences:

>Translated_300_residues
MENVGLAIFNVLLVVCAAPLLDGVLRQVKARIHSRQGPPILQTYFDLAKLLVKEDQRGVNQLLFAWAPVVCMASVILSAL
FVPMAGLSPLGFSGDAIVFLYVLTMAPLCMCLGGMASGSPYAYAGANREIMTLMAVEPVVAICLITSGIRAHSLNLADCV
NAYAAGAPALSMIIATIAFFLILPAELSKVPFDQAEAETEIMEGPLIEYSGRKLALFKWSFYAKQIVLITLFVEWFLPWP
HMNFVPLDILATLIKVVIVAVIIEVIAQIFPRFKIHQSIRYFYAVVAFSVGGLVLAVMGL
>Mature_300_residues
MENVGLAIFNVLLVVCAAPLLDGVLRQVKARIHSRQGPPILQTYFDLAKLLVKEDQRGVNQLLFAWAPVVCMASVILSAL
FVPMAGLSPLGFSGDAIVFLYVLTMAPLCMCLGGMASGSPYAYAGANREIMTLMAVEPVVAICLITSGIRAHSLNLADCV
NAYAAGAPALSMIIATIAFFLILPAELSKVPFDQAEAETEIMEGPLIEYSGRKLALFKWSFYAKQIVLITLFVEWFLPWP
HMNFVPLDILATLIKVVIVAVIIEVIAQIFPRFKIHQSIRYFYAVVAFSVGGLVLAVMGL

Specific function: Unknown

COG id: COG0650

COG function: function code C; Formate hydrogenlyase subunit 4

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=261, Percent_Identity=26.0536398467433, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI87082115, Length=235, Percent_Identity=37.0212765957447, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789077, Length=291, Percent_Identity=30.5841924398625, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1788618, Length=237, Percent_Identity=29.1139240506329, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 32624; Mature: 32624

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENVGLAIFNVLLVVCAAPLLDGVLRQVKARIHSRQGPPILQTYFDLAKLLVKEDQRGVN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
QLLFAWAPVVCMASVILSALFVPMAGLSPLGFSGDAIVFLYVLTMAPLCMCLGGMASGSP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
YAYAGANREIMTLMAVEPVVAICLITSGIRAHSLNLADCVNAYAAGAPALSMIIATIAFF
CEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHH
LILPAELSKVPFDQAEAETEIMEGPLIEYSGRKLALFKWSFYAKQIVLITLFVEWFLPWP
HHHHHHHHCCCCCHHHHHHHHHCCCCEEECCCEEEEEEHHHHHHHHHHHHHHHHHHCCCC
HMNFVPLDILATLIKVVIVAVIIEVIAQIFPRFKIHQSIRYFYAVVAFSVGGLVLAVMGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MENVGLAIFNVLLVVCAAPLLDGVLRQVKARIHSRQGPPILQTYFDLAKLLVKEDQRGVN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
QLLFAWAPVVCMASVILSALFVPMAGLSPLGFSGDAIVFLYVLTMAPLCMCLGGMASGSP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
YAYAGANREIMTLMAVEPVVAICLITSGIRAHSLNLADCVNAYAAGAPALSMIIATIAFF
CEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHH
LILPAELSKVPFDQAEAETEIMEGPLIEYSGRKLALFKWSFYAKQIVLITLFVEWFLPWP
HHHHHHHHCCCCCHHHHHHHHHCCCCEEECCCEEEEEEHHHHHHHHHHHHHHHHHHCCCC
HMNFVPLDILATLIKVVIVAVIIEVIAQIFPRFKIHQSIRYFYAVVAFSVGGLVLAVMGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton; reduced ferredoxin [C]

Specific reaction: Proton + reduced ferredoxin = H2 + oxidized ferredoxin [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]