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The map label for this gene is garP [H]

Identifier: 83591165

GI number: 83591165

Start: 2465846

End: 2467186

Strand: Reverse

Name: garP [H]

Synonym: Moth_2345

Alternate gene names: 83591165

Gene position: 2467186-2465846 (Counterclockwise)

Preceding gene: 83591166

Following gene: 83591164

Centisome position: 93.85

GC content: 42.73

Gene sequence:

>1341_bases
ATGAATAAGGAAAACAGTAACAGTAGCCTGATTACATGGTGGCGTTACCGGTACCTTATTGCGAGCATTCTATTTTTTGC
ATATAGCATCCAGTACCTGGATCGGATTAAAACAACAGCCCTTATTCCCCTGATTATGGATAGTATTCATCTTAGTCACG
CCGATGTAGGTAACGGTATTTTCTTAATGCTAATTTTTTATGGACCGTCACAATTCATTTCAGGGATTATATGCGACAAA
TACGGCGCTAAGAAAGTACTTATCTTTTCATTGATTGGCTGGAGCCTTCTAACTTTTTGGATGGCATTCTTACAATCCAG
GGACGAGTGGTACATCCGGAACGCCCTTTTTGGAATTTTTATTGGAACTGAATTTATACCTAGTGCCCGCCTTCTTTCAC
GGTGGTTCCCATCACGGCAGCGAGCACGGGCTCAAAGCAGTCTTTCCTGGGCTTGGATCCTTACACCGGCATGGGCTACT
ATTGTAGCAACACAGCTTGCTTCATTTTTTGGCAGCTGGCGTCCCGTATTTATAGTGGTTGCAATTATTGGCTTAGTTCC
CTTGGCATTAATAATCTGGCTAATTAAAGACCGTCCAGAACAGGTTAAACATCTTTCATTAGCAGAAATAAAGGAAAGTT
ACGAGGATGAGATTTCCTCGGGCGTAATCTCCAGTGATGAAATTAATAGGAGAGAAGTATCTACCCAAACTATCAAAAAG
GCACAGATCCCCCTCCGTAATATACTTACTTATCGTGGCTTTTGGGCGATAGCTTTTGTTGATATTGCCTCCCAGATGAT
GTACTGGGGAGTTGTATCTTGGTCGCCAACCTATCTTAAAGACGTATTTAAGTTTAGTATAACAGGGATGGGTTTCTGGG
CTTCTATTTATTTTGCTGCGGGTGTATTGGGTGCCTATTTGAGTTCTATTATCAGTGATAAAGTGATGAAATCAAAAAGA
AAACCCATGATTGTTATTTCCTTTTTAGGCACCCTTCCTTTTATTGTCATATTATCGCAGTTGCATTCAGGAGTCAGTCA
TGCTGTCATTTTGCTTGTGCTCTCTTGTGCGGGATTCTTTGCTAATATGGCCTGGGGCCCCTTCCTTTCCTGGCCGGCGG
ACGTTTTTTCTCCTGAGGTTTACGGTACTGCCATGGGCTTCGTAAACATGCTGGCATATATCGGAGGAGCATTTGCACCC
TTAATTATGAGCCGCCTAATCCGTGTAGGCCAGGTTGGCCCCGACTATACCTATGCTTGGATTTTTATCGCTTGTGCTGC
TTTCGTCGGATTCATTGCTTCCTGCCTTGTAAAGGATAAAAAATATAGTCAGGCTAATTAG

Upstream 100 bases:

>100_bases
AATGTGCTATTCCTTTGACAACGCCCCTTGAAAACATTTTAGCTATTACTGAAACCGCAAAAGAATATCAAATTCATAAA
AAACTAGGAGGGGAGACACA

Downstream 100 bases:

>100_bases
TTGGCATTTTGCAAGAATCCGATAGTAAAATTGTCACCTCGATCTATAATTATTTGGTTTTATTACGTTGTTAAAAGACC
TTAAAAAATTCAAGAGGGAT

Product: major facilitator transporter

Products: NA

Alternate protein names: D-galactarate permease [H]

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MNKENSNSSLITWWRYRYLIASILFFAYSIQYLDRIKTTALIPLIMDSIHLSHADVGNGIFLMLIFYGPSQFISGIICDK
YGAKKVLIFSLIGWSLLTFWMAFLQSRDEWYIRNALFGIFIGTEFIPSARLLSRWFPSRQRARAQSSLSWAWILTPAWAT
IVATQLASFFGSWRPVFIVVAIIGLVPLALIIWLIKDRPEQVKHLSLAEIKESYEDEISSGVISSDEINRREVSTQTIKK
AQIPLRNILTYRGFWAIAFVDIASQMMYWGVVSWSPTYLKDVFKFSITGMGFWASIYFAAGVLGAYLSSIISDKVMKSKR
KPMIVISFLGTLPFIVILSQLHSGVSHAVILLVLSCAGFFANMAWGPFLSWPADVFSPEVYGTAMGFVNMLAYIGGAFAP
LIMSRLIRVGQVGPDYTYAWIFIACAAFVGFIASCLVKDKKYSQAN

Sequences:

>Translated_446_residues
MNKENSNSSLITWWRYRYLIASILFFAYSIQYLDRIKTTALIPLIMDSIHLSHADVGNGIFLMLIFYGPSQFISGIICDK
YGAKKVLIFSLIGWSLLTFWMAFLQSRDEWYIRNALFGIFIGTEFIPSARLLSRWFPSRQRARAQSSLSWAWILTPAWAT
IVATQLASFFGSWRPVFIVVAIIGLVPLALIIWLIKDRPEQVKHLSLAEIKESYEDEISSGVISSDEINRREVSTQTIKK
AQIPLRNILTYRGFWAIAFVDIASQMMYWGVVSWSPTYLKDVFKFSITGMGFWASIYFAAGVLGAYLSSIISDKVMKSKR
KPMIVISFLGTLPFIVILSQLHSGVSHAVILLVLSCAGFFANMAWGPFLSWPADVFSPEVYGTAMGFVNMLAYIGGAFAP
LIMSRLIRVGQVGPDYTYAWIFIACAAFVGFIASCLVKDKKYSQAN
>Mature_446_residues
MNKENSNSSLITWWRYRYLIASILFFAYSIQYLDRIKTTALIPLIMDSIHLSHADVGNGIFLMLIFYGPSQFISGIICDK
YGAKKVLIFSLIGWSLLTFWMAFLQSRDEWYIRNALFGIFIGTEFIPSARLLSRWFPSRQRARAQSSLSWAWILTPAWAT
IVATQLASFFGSWRPVFIVVAIIGLVPLALIIWLIKDRPEQVKHLSLAEIKESYEDEISSGVISSDEINRREVSTQTIKK
AQIPLRNILTYRGFWAIAFVDIASQMMYWGVVSWSPTYLKDVFKFSITGMGFWASIYFAAGVLGAYLSSIISDKVMKSKR
KPMIVISFLGTLPFIVILSQLHSGVSHAVILLVLSCAGFFANMAWGPFLSWPADVFSPEVYGTAMGFVNMLAYIGGAFAP
LIMSRLIRVGQVGPDYTYAWIFIACAAFVGFIASCLVKDKKYSQAN

Specific function: Uptake of D-galactarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=456, Percent_Identity=24.5614035087719, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1789515, Length=438, Percent_Identity=25.7990867579909, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788573, Length=395, Percent_Identity=23.7974683544304, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI87082310, Length=401, Percent_Identity=24.4389027431421, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI87082320, Length=435, Percent_Identity=22.2988505747126, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI2367379, Length=418, Percent_Identity=20.8133971291866, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789152, Length=450, Percent_Identity=24.6666666666667, Blast_Score=79, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17560030, Length=353, Percent_Identity=21.8130311614731, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17552542, Length=370, Percent_Identity=22.4324324324324, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24654215, Length=367, Percent_Identity=23.9782016348774, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19922400, Length=367, Percent_Identity=23.9782016348774, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24648416, Length=439, Percent_Identity=24.6013667425968, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356189, Length=439, Percent_Identity=24.6013667425968, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24584153, Length=361, Percent_Identity=24.0997229916898, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20130135, Length=434, Percent_Identity=21.889400921659, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24655271, Length=419, Percent_Identity=21.9570405727924, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20130167, Length=442, Percent_Identity=21.4932126696833, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50261; Mature: 50261

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKENSNSSLITWWRYRYLIASILFFAYSIQYLDRIKTTALIPLIMDSIHLSHADVGNGI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FLMLIFYGPSQFISGIICDKYGAKKVLIFSLIGWSLLTFWMAFLQSRDEWYIRNALFGIF
EEEEEHHCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IGTEFIPSARLLSRWFPSRQRARAQSSLSWAWILTPAWATIVATQLASFFGSWRPVFIVV
HHHHHCCHHHHHHHHCCCHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCCHHHHHHH
AIIGLVPLALIIWLIKDRPEQVKHLSLAEIKESYEDEISSGVISSDEINRREVSTQTIKK
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
AQIPLRNILTYRGFWAIAFVDIASQMMYWGVVSWSPTYLKDVFKFSITGMGFWASIYFAA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
GVLGAYLSSIISDKVMKSKRKPMIVISFLGTLPFIVILSQLHSGVSHAVILLVLSCAGFF
HHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANMAWGPFLSWPADVFSPEVYGTAMGFVNMLAYIGGAFAPLIMSRLIRVGQVGPDYTYAW
HHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
IFIACAAFVGFIASCLVKDKKYSQAN
HHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNKENSNSSLITWWRYRYLIASILFFAYSIQYLDRIKTTALIPLIMDSIHLSHADVGNGI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FLMLIFYGPSQFISGIICDKYGAKKVLIFSLIGWSLLTFWMAFLQSRDEWYIRNALFGIF
EEEEEHHCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IGTEFIPSARLLSRWFPSRQRARAQSSLSWAWILTPAWATIVATQLASFFGSWRPVFIVV
HHHHHCCHHHHHHHHCCCHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCCHHHHHHH
AIIGLVPLALIIWLIKDRPEQVKHLSLAEIKESYEDEISSGVISSDEINRREVSTQTIKK
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
AQIPLRNILTYRGFWAIAFVDIASQMMYWGVVSWSPTYLKDVFKFSITGMGFWASIYFAA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
GVLGAYLSSIISDKVMKSKRKPMIVISFLGTLPFIVILSQLHSGVSHAVILLVLSCAGFF
HHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANMAWGPFLSWPADVFSPEVYGTAMGFVNMLAYIGGAFAPLIMSRLIRVGQVGPDYTYAW
HHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
IFIACAAFVGFIASCLVKDKKYSQAN
HHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]