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The map label for this gene is hemE [H]

Identifier: 83591164

GI number: 83591164

Start: 2464683

End: 2465741

Strand: Reverse

Name: hemE [H]

Synonym: Moth_2344

Alternate gene names: 83591164

Gene position: 2465741-2464683 (Counterclockwise)

Preceding gene: 83591165

Following gene: 83591163

Centisome position: 93.8

GC content: 44.0

Gene sequence:

>1059_bases
ATGTTAAATTACCATGAGATTTTAGCAACAGCAATGTTCAGACCCATAAATCCCCATGTTCCCGTTGTATTATGGGCTAT
AGGGCAGACTTATGCCCCCTTTGCTAAAATACCGGATAATGAGTACTATGCCGATCCGGCGAAAATGCTGGAAGCCCAGG
TGAAGTTTTACGAACGTTTCCCTGATGTATTAACCATTCCCGGAATTTGGCCGGATCTTGGTCTGATGGCGGAACTGGGG
GCTTTAGGAGCAGAGTTAGAGTTTCCGGATGATGCCCCTCCTCAGTCCAGGGGTGGGGCCTTTGAAGATATCAGGGAAGT
AGAAAATTGGGAAGTCCCCGATCCTAAAAAGGCGGATTATACCTCTCAGACGCTAGATTACCTTAAGTATTTCTGTAAGC
ATTTACCGGAAGAACCCAGGAAGAAGTGGGGATTCTTAGATGGGCACATTTTCTGCGGTGGACCTGGTGAGATCTCAGGG
TTATTACTCGGGTATGATAAATTTTCTTATGCAATGTATGATTATCCGCAGCTCGTGCATATTCTGCTGCGTAAGGTAAC
TGATTTTATTAAAAGCTATATTGATGCCCAAATAGAAATAGTTGGGGAACCTAAAAGGGTAATCATATGGGATCATATTC
CCGGTATGTTGTCAAGAGAGCTTTTTGATGAATTTATCCATCCTTATATGAAAGAGGTGTTTACCCATGTAGAAAAGGCG
ACCCTGAGGATATACCATAACGAGAATAATTACCCCCATCTCCTTGATTTAATGCGGGATATCCCGGCCAACGTCTGCCA
TATCGGCCCCAAACACGATCTGGTCGAGAGCAAAAGGGTTTTAAAAAAATGTGTAATGGGAAACGTTCATCCTATCCAGG
AATTATTGCTGGGTACAAATGAGGAAATTGAAGCAAAGTGTAAAACCATAATTGAAACTGCAGGAAGAGGTGGCGGTTTA
TGGCTTTCAACCGGAGGCGGTATGGCCCCGGAAACACCGGTGGAGAAAATGCAGGTCCTCATTGACTGTACTAAAAAATA
TCTGCCACCTTCGCTGTAA

Upstream 100 bases:

>100_bases
CATTTTGCAAGAATCCGATAGTAAAATTGTCACCTCGATCTATAATTATTTGGTTTTATTACGTTGTTAAAAGACCTTAA
AAAATTCAAGAGGGATAATT

Downstream 100 bases:

>100_bases
TGCTAAAGTATAAAAACCGGTGGTGGCGCAATACAGCCACCCCGGCTTTTTTTGAGTAGGTCCTGGCATATTCAATAGGT
TAGGTTTATAGAGTGCAGTT

Product: uroporphyrinogen decarboxylase

Products: NA

Alternate protein names: UPD; URO-D [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MLNYHEILATAMFRPINPHVPVVLWAIGQTYAPFAKIPDNEYYADPAKMLEAQVKFYERFPDVLTIPGIWPDLGLMAELG
ALGAELEFPDDAPPQSRGGAFEDIREVENWEVPDPKKADYTSQTLDYLKYFCKHLPEEPRKKWGFLDGHIFCGGPGEISG
LLLGYDKFSYAMYDYPQLVHILLRKVTDFIKSYIDAQIEIVGEPKRVIIWDHIPGMLSRELFDEFIHPYMKEVFTHVEKA
TLRIYHNENNYPHLLDLMRDIPANVCHIGPKHDLVESKRVLKKCVMGNVHPIQELLLGTNEEIEAKCKTIIETAGRGGGL
WLSTGGGMAPETPVEKMQVLIDCTKKYLPPSL

Sequences:

>Translated_352_residues
MLNYHEILATAMFRPINPHVPVVLWAIGQTYAPFAKIPDNEYYADPAKMLEAQVKFYERFPDVLTIPGIWPDLGLMAELG
ALGAELEFPDDAPPQSRGGAFEDIREVENWEVPDPKKADYTSQTLDYLKYFCKHLPEEPRKKWGFLDGHIFCGGPGEISG
LLLGYDKFSYAMYDYPQLVHILLRKVTDFIKSYIDAQIEIVGEPKRVIIWDHIPGMLSRELFDEFIHPYMKEVFTHVEKA
TLRIYHNENNYPHLLDLMRDIPANVCHIGPKHDLVESKRVLKKCVMGNVHPIQELLLGTNEEIEAKCKTIIETAGRGGGL
WLSTGGGMAPETPVEKMQVLIDCTKKYLPPSL
>Mature_352_residues
MLNYHEILATAMFRPINPHVPVVLWAIGQTYAPFAKIPDNEYYADPAKMLEAQVKFYERFPDVLTIPGIWPDLGLMAELG
ALGAELEFPDDAPPQSRGGAFEDIREVENWEVPDPKKADYTSQTLDYLKYFCKHLPEEPRKKWGFLDGHIFCGGPGEISG
LLLGYDKFSYAMYDYPQLVHILLRKVTDFIKSYIDAQIEIVGEPKRVIIWDHIPGMLSRELFDEFIHPYMKEVFTHVEKA
TLRIYHNENNYPHLLDLMRDIPANVCHIGPKHDLVESKRVLKKCVMGNVHPIQELLLGTNEEIEAKCKTIIETAGRGGGL
WLSTGGGMAPETPVEKMQVLIDCTKKYLPPSL

Specific function: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III [H]

COG id: COG0407

COG function: function code H; Uroporphyrinogen-III decarboxylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uroporphyrinogen decarboxylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006361
- InterPro:   IPR000257 [H]

Pfam domain/function: PF01208 URO-D [H]

EC number: =4.1.1.37 [H]

Molecular weight: Translated: 40083; Mature: 40083

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNYHEILATAMFRPINPHVPVVLWAIGQTYAPFAKIPDNEYYADPAKMLEAQVKFYERF
CCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHC
PDVLTIPGIWPDLGLMAELGALGAELEFPDDAPPQSRGGAFEDIREVENWEVPDPKKADY
CCCEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCH
TSQTLDYLKYFCKHLPEEPRKKWGFLDGHIFCGGPGEISGLLLGYDKFSYAMYDYPQLVH
HHHHHHHHHHHHHHCCCCHHHHCCCCCCEEEECCCCCCCEEEEECHHHHHHHHHHHHHHH
ILLRKVTDFIKSYIDAQIEIVGEPKRVIIWDHIPGMLSRELFDEFIHPYMKEVFTHVEKA
HHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TLRIYHNENNYPHLLDLMRDIPANVCHIGPKHDLVESKRVLKKCVMGNVHPIQELLLGTN
HEEEEECCCCCHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCC
EEIEAKCKTIIETAGRGGGLWLSTGGGMAPETPVEKMQVLIDCTKKYLPPSL
HHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLNYHEILATAMFRPINPHVPVVLWAIGQTYAPFAKIPDNEYYADPAKMLEAQVKFYERF
CCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHC
PDVLTIPGIWPDLGLMAELGALGAELEFPDDAPPQSRGGAFEDIREVENWEVPDPKKADY
CCCEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCH
TSQTLDYLKYFCKHLPEEPRKKWGFLDGHIFCGGPGEISGLLLGYDKFSYAMYDYPQLVH
HHHHHHHHHHHHHHCCCCHHHHCCCCCCEEEECCCCCCCEEEEECHHHHHHHHHHHHHHH
ILLRKVTDFIKSYIDAQIEIVGEPKRVIIWDHIPGMLSRELFDEFIHPYMKEVFTHVEKA
HHHHHHHHHHHHHHCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TLRIYHNENNYPHLLDLMRDIPANVCHIGPKHDLVESKRVLKKCVMGNVHPIQELLLGTN
HEEEEECCCCCHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCC
EEIEAKCKTIIETAGRGGGLWLSTGGGMAPETPVEKMQVLIDCTKKYLPPSL
HHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA