Click here to switch to the map view.

The map label for this gene is pabA [H]

Identifier: 83590188

GI number: 83590188

Start: 1387055

End: 1387669

Strand: Reverse

Name: pabA [H]

Synonym: Moth_1341

Alternate gene names: 83590188

Gene position: 1387669-1387055 (Counterclockwise)

Preceding gene: 83590189

Following gene: 83590187

Centisome position: 52.79

GC content: 55.61

Gene sequence:

>615_bases
GTGCTGCTAATGATTGATAACTATGATTCCTTTACCTATAACCTGGTGCAGTACTTCCTGGAACTGGGGCAGGAGGTGGT
GGTACGGCGTAATGACGCCATAACCCTGGAGGAGATTGCTGAACTAAACCCCGATTACCTGGTCCTTTCCCCCGGCCCTT
GCACGCCCAATGAAGCCGGTATCTCCTTGGCGGCCATCACCGCCTTTGCCGGCAAGATACCCATCCTGGGCGTCTGCCTG
GGCCACCAGAGCATTGCCCAGGCCTTCGGCGGTCGGATAGTGCGGGCCGGACGGCTCATGCATGGCAAGACTTCTACCAT
TACCCATGATGGTAAAACAATTTACCGGGACCTGCCCAACCCCTTTACAGCTACCCGCTATCATTCCTTAATCGTCGATG
AGGAGACCCTGCCGGATTGCCTGGAGGTGACGGCCCGGAGCGAAACCGGCGAGCTAATGGGCCTGCGCCACCGCCAGTTA
CCAGTTGAAGGTGTCCAATTTCACCCCGAGTCCATCCTGACAACGGTGGGCAAGCAACTGCTAAGGAATTTTTTGGCCAT
TGGCCCCTTCGCGAGGACCAGAAGTAAAGAAAATGGAGTCAGCCTGGATAAATAA

Upstream 100 bases:

>100_bases
GGCATTGTCGCCGACTCCGACCCGGAAGCCGAATATGAAGAGACCCTGAACAAAGCCCGGGCGCTGTTGCAGGTATTAAA
AAAGCCGGAGGTGGGCACCC

Downstream 100 bases:

>100_bases
TTACTGTATTTTTGAGAGGAGTTGAGCTTAGTGTTGAAAGCCCAGATTAGCAAAGTAGTAGCCGGCCAGCACTTGAGCGA
AGCCGAGGCCGCAGAAGCCA

Product: anthranilate synthase, component II

Products: NA

Alternate protein names: Para-aminobenzoate synthase glutamine amidotransferase component II; ADC synthase; Anthranilate synthase component II [H]

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MLLMIDNYDSFTYNLVQYFLELGQEVVVRRNDAITLEEIAELNPDYLVLSPGPCTPNEAGISLAAITAFAGKIPILGVCL
GHQSIAQAFGGRIVRAGRLMHGKTSTITHDGKTIYRDLPNPFTATRYHSLIVDEETLPDCLEVTARSETGELMGLRHRQL
PVEGVQFHPESILTTVGKQLLRNFLAIGPFARTRSKENGVSLDK

Sequences:

>Translated_204_residues
MLLMIDNYDSFTYNLVQYFLELGQEVVVRRNDAITLEEIAELNPDYLVLSPGPCTPNEAGISLAAITAFAGKIPILGVCL
GHQSIAQAFGGRIVRAGRLMHGKTSTITHDGKTIYRDLPNPFTATRYHSLIVDEETLPDCLEVTARSETGELMGLRHRQL
PVEGVQFHPESILTTVGKQLLRNFLAIGPFARTRSKENGVSLDK
>Mature_204_residues
MLLMIDNYDSFTYNLVQYFLELGQEVVVRRNDAITLEEIAELNPDYLVLSPGPCTPNEAGISLAAITAFAGKIPILGVCL
GHQSIAQAFGGRIVRAGRLMHGKTSTITHDGKTIYRDLPNPFTATRYHSLIVDEETLPDCLEVTARSETGELMGLRHRQL
PVEGVQFHPESILTTVGKQLLRNFLAIGPFARTRSKENGVSLDK

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine and also involved in the synthesis of anthranilate [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=65.4054054054054, Blast_Score=270, Evalue=7e-74,
Organism=Escherichia coli, GI1787517, Length=188, Percent_Identity=46.2765957446808, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI1786215, Length=139, Percent_Identity=33.0935251798561, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1788854, Length=190, Percent_Identity=25.7894736842105, Blast_Score=61, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322638, Length=206, Percent_Identity=49.0291262135922, Blast_Score=213, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6324361, Length=215, Percent_Identity=31.6279069767442, Blast_Score=78, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6323873, Length=151, Percent_Identity=29.1390728476821, Blast_Score=66, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322331, Length=168, Percent_Identity=32.1428571428571, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85; =4.1.3.27 [H]

Molecular weight: Translated: 22508; Mature: 22508

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLMIDNYDSFTYNLVQYFLELGQEVVVRRNDAITLEEIAELNPDYLVLSPGPCTPNEAG
CEEEEECCCCHHHHHHHHHHHHCHHHEECCCCCCCHHHHHHCCCCEEEECCCCCCCCCCC
ISLAAITAFAGKIPILGVCLGHQSIAQAFGGRIVRAGRLMHGKTSTITHDGKTIYRDLPN
CHHHHHHHHHCCCCEEEEECCHHHHHHHHCCEEEECCEEECCCCCEEEECCCHHHHCCCC
PFTATRYHSLIVDEETLPDCLEVTARSETGELMGLRHRQLPVEGVQFHPESILTTVGKQL
CCCHHHHHHEEECCCCCHHHHHHHCCCCCCHHHCCHHHCCCCCCCEECHHHHHHHHHHHH
LRNFLAIGPFARTRSKENGVSLDK
HHHHHHHCCHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLLMIDNYDSFTYNLVQYFLELGQEVVVRRNDAITLEEIAELNPDYLVLSPGPCTPNEAG
CEEEEECCCCHHHHHHHHHHHHCHHHEECCCCCCCHHHHHHCCCCEEEECCCCCCCCCCC
ISLAAITAFAGKIPILGVCLGHQSIAQAFGGRIVRAGRLMHGKTSTITHDGKTIYRDLPN
CHHHHHHHHHCCCCEEEEECCHHHHHHHHCCEEEECCEEECCCCCEEEECCCHHHHCCCC
PFTATRYHSLIVDEETLPDCLEVTARSETGELMGLRHRQLPVEGVQFHPESILTTVGKQL
CCCHHHHHHEEECCCCCHHHHHHHCCCCCCHHHCCHHHCCCCCCCEECHHHHHHHHHHHH
LRNFLAIGPFARTRSKENGVSLDK
HHHHHHHCCHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]