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The map label for this gene is trpE [H]

Identifier: 83590189

GI number: 83590189

Start: 1387653

End: 1389152

Strand: Reverse

Name: trpE [H]

Synonym: Moth_1342

Alternate gene names: 83590189

Gene position: 1389152-1387653 (Counterclockwise)

Preceding gene: 83590190

Following gene: 83590188

Centisome position: 52.84

GC content: 59.67

Gene sequence:

>1500_bases
GTGTTTCACCCTGACCGGGCAACCTACCTGGACCTGGCCCGGAAGGCCCCTTATATTCCTGTCTGGACAGAGATTCTTGC
CGATACAGAAACTCCCATTTCCCTGTACTTAAAATTCGCCGGCGGTCCGGACAGCTTCTTACTGGAGAGTGTCGAAGGCG
GGGAAAACCTGGGCCGCTATTCCCTCATTGGCTTCGATCCCCTGCTGACCTTCACCGCCAGGAGTGGTAAGGCTTATTTA
AGCACGAATAACGCCACTGCCAGGTTGCTGGAAGAAAAACCCTTCAAGGCTTTAAACAATTTAATGGCCAGCCTGTCCCT
ACCACCTAGTGAGGGACCACGCTTTCAGGGCGGCCTGGTAGGCTACCTGGGATATGATATGGTCCGGGAACTGGAGGCTT
TGCCCCCGGGGCCCGGTAATGACCTGCAAATACCAGATACCCACCTGACCCTCCACCGTTGTTACCTGGTTTACGACCAT
ATCCTGCGGACAGTGAGGATAACCTGCCTGGGGCGAGGCGGGGAGAATGCCCTTGCCGGGTATGAAGAAGCTGTAGCCGG
GGTCAAGGGAATTCTGGAAAAACTCGGGCGATCTTCTGGCGGGTACCGGAATGGGTATCCGCCGGCAGCAGGGCAACTGG
TCCCGGAAGGGGTCTCCTGGCAGGCCAGCGTGACCCGACAGGAATTTACCGGGATGGTTACAAAAGCTAAGGAGTATATC
GCCGCCGGCGATATCTTCCAGGTGGTCCTCTCCCAGAGATTGAGCCTGCCCTTCAGGGAGGACGCCCTGGTCGTTTACCG
GCACTTGCGAGCCCTTAACCCTTCGCCGTATATGTTTTACCTTAACTTCCCGGAGGTGCAACTGGTAGGCGCATCGCCGG
AAATGCTGGTGCGGGTGGAAAGGGGAACAATCGATTATCGCCCCATCGCCGGTACCAGGCGCCGGGGACGGACTGCTGCC
GAGGACAGGGCCCTGGCCGCGGAACTCCTGGCCAGCGAGAAGGAGCGTGCCGAACACCTGATGCTCCTGGACCTGGGGCG
GAACGACGTGGGAAGGATAGCCGTCCCGGGCAGCCTGCAGGTGACCCGGCAGATGGTGGTGGAGTATTATTCCCACGTCA
TGCACCTGGTTTCCAGCATTACCGCCCGCCTGGCTCCTGGCAGGAGTGCCCTGGACGCCCTTCTGGCCTGTTTCCCCGCC
GGTACGGTGACCGGGGCTCCCAAGGTACGGGCCATGGAGATCATCACCGAACTGGAGCCGGTCAACCGGGGACCCTATGC
CGGCGCCGTAGGTTACCTGGGTCTCCATGGCAACCTGGATACCTGCATTGCCATCCGCACCATAGTTTTTGCCCGGGGTC
GGGCCTTCATCCAGGCCGGGGCGGGCATTGTCGCCGACTCCGACCCGGAAGCCGAATATGAAGAGACCCTGAACAAAGCC
CGGGCGCTGTTGCAGGTATTAAAAAAGCCGGAGGTGGGCACCCGTGCTGCTAATGATTGA

Upstream 100 bases:

>100_bases
TGGAGTTTAGCTTAGAGTTGAGCTTGATTAAGGGTAAAGTTTTACCAGGGCTCATCTTTGAGCGCTGGTTTTTATTTTGC
CCCTGGGGAGGGAGAAAGCA

Downstream 100 bases:

>100_bases
TAACTATGATTCCTTTACCTATAACCTGGTGCAGTACTTCCTGGAACTGGGGCAGGAGGTGGTGGTACGGCGTAATGACG
CCATAACCCTGGAGGAGATT

Product: anthranilate synthase, component I

Products: NA

Alternate protein names: Anthranilate synthase component I [H]

Number of amino acids: Translated: 499; Mature: 499

Protein sequence:

>499_residues
MFHPDRATYLDLARKAPYIPVWTEILADTETPISLYLKFAGGPDSFLLESVEGGENLGRYSLIGFDPLLTFTARSGKAYL
STNNATARLLEEKPFKALNNLMASLSLPPSEGPRFQGGLVGYLGYDMVRELEALPPGPGNDLQIPDTHLTLHRCYLVYDH
ILRTVRITCLGRGGENALAGYEEAVAGVKGILEKLGRSSGGYRNGYPPAAGQLVPEGVSWQASVTRQEFTGMVTKAKEYI
AAGDIFQVVLSQRLSLPFREDALVVYRHLRALNPSPYMFYLNFPEVQLVGASPEMLVRVERGTIDYRPIAGTRRRGRTAA
EDRALAAELLASEKERAEHLMLLDLGRNDVGRIAVPGSLQVTRQMVVEYYSHVMHLVSSITARLAPGRSALDALLACFPA
GTVTGAPKVRAMEIITELEPVNRGPYAGAVGYLGLHGNLDTCIAIRTIVFARGRAFIQAGAGIVADSDPEAEYEETLNKA
RALLQVLKKPEVGTRAAND

Sequences:

>Translated_499_residues
MFHPDRATYLDLARKAPYIPVWTEILADTETPISLYLKFAGGPDSFLLESVEGGENLGRYSLIGFDPLLTFTARSGKAYL
STNNATARLLEEKPFKALNNLMASLSLPPSEGPRFQGGLVGYLGYDMVRELEALPPGPGNDLQIPDTHLTLHRCYLVYDH
ILRTVRITCLGRGGENALAGYEEAVAGVKGILEKLGRSSGGYRNGYPPAAGQLVPEGVSWQASVTRQEFTGMVTKAKEYI
AAGDIFQVVLSQRLSLPFREDALVVYRHLRALNPSPYMFYLNFPEVQLVGASPEMLVRVERGTIDYRPIAGTRRRGRTAA
EDRALAAELLASEKERAEHLMLLDLGRNDVGRIAVPGSLQVTRQMVVEYYSHVMHLVSSITARLAPGRSALDALLACFPA
GTVTGAPKVRAMEIITELEPVNRGPYAGAVGYLGLHGNLDTCIAIRTIVFARGRAFIQAGAGIVADSDPEAEYEETLNKA
RALLQVLKKPEVGTRAAND
>Mature_499_residues
MFHPDRATYLDLARKAPYIPVWTEILADTETPISLYLKFAGGPDSFLLESVEGGENLGRYSLIGFDPLLTFTARSGKAYL
STNNATARLLEEKPFKALNNLMASLSLPPSEGPRFQGGLVGYLGYDMVRELEALPPGPGNDLQIPDTHLTLHRCYLVYDH
ILRTVRITCLGRGGENALAGYEEAVAGVKGILEKLGRSSGGYRNGYPPAAGQLVPEGVSWQASVTRQEFTGMVTKAKEYI
AAGDIFQVVLSQRLSLPFREDALVVYRHLRALNPSPYMFYLNFPEVQLVGASPEMLVRVERGTIDYRPIAGTRRRGRTAA
EDRALAAELLASEKERAEHLMLLDLGRNDVGRIAVPGSLQVTRQMVVEYYSHVMHLVSSITARLAPGRSALDALLACFPA
GTVTGAPKVRAMEIITELEPVNRGPYAGAVGYLGLHGNLDTCIAIRTIVFARGRAFIQAGAGIVADSDPEAEYEETLNKA
RALLQVLKKPEVGTRAAND

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=456, Percent_Identity=34.8684210526316, Blast_Score=268, Evalue=9e-73,
Organism=Escherichia coli, GI1787518, Length=413, Percent_Identity=40.4358353510896, Blast_Score=244, Evalue=7e-66,
Organism=Escherichia coli, GI1786809, Length=279, Percent_Identity=31.1827956989247, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI87082077, Length=270, Percent_Identity=29.6296296296296, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320935, Length=476, Percent_Identity=38.8655462184874, Blast_Score=308, Evalue=9e-85,
Organism=Saccharomyces cerevisiae, GI6324361, Length=412, Percent_Identity=25.7281553398058, Blast_Score=116, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR005256
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 54386; Mature: 54386

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFHPDRATYLDLARKAPYIPVWTEILADTETPISLYLKFAGGPDSFLLESVEGGENLGRY
CCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCE
SLIGFDPLLTFTARSGKAYLSTNNATARLLEEKPFKALNNLMASLSLPPSEGPRFQGGLV
EEEECCHHHEEEECCCEEEEECCCHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCEE
GYLGYDMVRELEALPPGPGNDLQIPDTHLTLHRCYLVYDHILRTVRITCLGRGGENALAG
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHH
YEEAVAGVKGILEKLGRSSGGYRNGYPPAAGQLVPEGVSWQASVTRQEFTGMVTKAKEYI
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AAGDIFQVVLSQRLSLPFREDALVVYRHLRALNPSPYMFYLNFPEVQLVGASPEMLVRVE
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCEEEECCCHHHEEEEE
RGTIDYRPIAGTRRRGRTAAEDRALAAELLASEKERAEHLMLLDLGRNDVGRIAVPGSLQ
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCEECCCHHH
VTRQMVVEYYSHVMHLVSSITARLAPGRSALDALLACFPAGTVTGAPKVRAMEIITELEP
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCC
VNRGPYAGAVGYLGLHGNLDTCIAIRTIVFARGRAFIQAGAGIVADSDPEAEYEETLNKA
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCHHEECCCCEEECCCCCHHHHHHHHHH
RALLQVLKKPEVGTRAAND
HHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MFHPDRATYLDLARKAPYIPVWTEILADTETPISLYLKFAGGPDSFLLESVEGGENLGRY
CCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCE
SLIGFDPLLTFTARSGKAYLSTNNATARLLEEKPFKALNNLMASLSLPPSEGPRFQGGLV
EEEECCHHHEEEECCCEEEEECCCHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCEE
GYLGYDMVRELEALPPGPGNDLQIPDTHLTLHRCYLVYDHILRTVRITCLGRGGENALAG
HHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHH
YEEAVAGVKGILEKLGRSSGGYRNGYPPAAGQLVPEGVSWQASVTRQEFTGMVTKAKEYI
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AAGDIFQVVLSQRLSLPFREDALVVYRHLRALNPSPYMFYLNFPEVQLVGASPEMLVRVE
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCEEEECCCHHHEEEEE
RGTIDYRPIAGTRRRGRTAAEDRALAAELLASEKERAEHLMLLDLGRNDVGRIAVPGSLQ
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCEECCCHHH
VTRQMVVEYYSHVMHLVSSITARLAPGRSALDALLACFPAGTVTGAPKVRAMEIITELEP
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCC
VNRGPYAGAVGYLGLHGNLDTCIAIRTIVFARGRAFIQAGAGIVADSDPEAEYEETLNKA
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCHHEECCCCEEECCCCCHHHHHHHHHH
RALLQVLKKPEVGTRAAND
HHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2732211 [H]