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The map label for this gene is pccB [H]

Identifier: 83590004

GI number: 83590004

Start: 1187963

End: 1189516

Strand: Reverse

Name: pccB [H]

Synonym: Moth_1156

Alternate gene names: 83590004

Gene position: 1189516-1187963 (Counterclockwise)

Preceding gene: 83590005

Following gene: 83590003

Centisome position: 45.25

GC content: 58.17

Gene sequence:

>1554_bases
ATGGAAGATATAACGGCCAGGCTGGCCGACCTGGAAGTCAGGCGCGCCAGGGTTATGGCCGGCGGTGGTGAAGAACGGGT
AGCCCGGCAGCACGCTGCCGGCAAGTTAACGGCCCGGGAACGGCTGGAGCTATTGCTGGATCCCGGCAGTTTTCTGGAAC
TGGATCAATTTGTGCGCCACCGGGCCACTGATTTCGGCATGCAGGACATAGAAACACCTGGTGAGGGTGTAGTTACCGGT
TCCGGGACCATAAATGGTCGGCCAGTCTACGTCTATGCCCAGGATTTTACCGTTATGGGCGGTTCCCTGGGGGAGATGCA
TGCTGCCAAAATCTGTAAGGTCATGGATCTAGCCCTGAAAACCGGTGTGCCGGTCATAGGTTTGAACGATTCCGGCGGGG
CCCGTATCCAGGAGGGGGTAGCGGCCCTCAATGGTTATGGGGAAATCTTCCGCCGCAACACCCATGCTTCAGGGGTTATT
CCCCAAATCGCCGCTATTATGGGCCCCTGTGCCGGGGGCGCCGTCTATTCGCCGGGGCTAATGGACTTCATTTTTATGGT
TGATAATACAGCCCAGATGTTTATTACCGGCCCCCAGGTAATCAAAGCCGTCACGGGGGAAGAAGTCAGCGCGGAAGAGC
TGGGAGGTGCCGTCACCCATGCCACCAGGAGCGGGGTGGCCCACTTCCGGACGCCAACGGAAGAAGATTGCCTGCACTTG
ATTCGCACCCTGCTGGATTATTTACCTGCCAATAACTTGGAGGACCCGCCCTTCAGGCCCAGTTCTGACCCGGCTGAGCG
CCAGAATCCCAACCTGGCGGCACTGGTGCCTGTCGATCCTAATAAACCGTATAACGTGAAGGAAATCATCTACGGAGTGG
TTGATGACGGCCTGTTCCTGGAGATTCAAGGTGAATATGCCGCCAATATGGTTATTGGCCTGGCCCGCTTGGCGGGGTAT
ACTATAGGTATTGTGGCCAACCAGCCCCAGTACCTGGCCGGTTGCCTGGATATCAACGCCGCCGATAAAGCAGCACGTTT
CGTGCGTTTTTGTGACGCCTTCAATATACCCCTCCTGACCCTGGTGGATACCCCCGGCTACCTTCCCGGGGTGGAACAGG
AACAGGGAGGCATTATCCGTCATGGGGCCAAACTGTTATATGCCTTCGCCGAGGCCACGGTACCCAAACTCACCCTCGTC
CTGCGCAAGGCGTACGGCGGTGCCTACCTGGCCATGTGCTCCCGCTCCCTGGGAGCCGATCATGTCGTTGCCTGGCCTAC
AGCGGAAATAGCCGTCATGGGTCCCGAGGGGGCTGCTAATATAATCTTCCGCCAGGAAATCAGCCAGGCAGATGACCCGG
CCCGGGTACGGCAGGAAAAAGTCGCCGCTTACCGCGATAAGTTTGCCAACCCCTATGTGGCCGCGGGCCTGGGGCTGGTT
GATGCTGTTATCGACCCGGCTCTGACCCGCCCCCATTTGATCCGGAACCTGCTGACCCTGCTCAGTAAACGGGAAAGCCG
CCCGGGTAAAAAACACGGCAACTTCCCTGTCTAG

Upstream 100 bases:

>100_bases
TGCCAAAGAAAGAACGGTTTTGAGAAGAAGGTACTTGCAAGCAACCCTTATGACCTGGTAATATAAGGAGGTAGGGAATA
AGAAAGGGGATAGTCAAACC

Downstream 100 bases:

>100_bases
GGAAAAGGAGGGAACGGATTTGTTAGCCTATCTCCAGACAGCACCCCGCCCGGCAATGATACCGGCGGAAATCGTAGCCG
CCATCACCGCCGCCGTAGCC

Product: carboxyl transferase

Products: NA

Alternate protein names: PCCase; Propanoyl-CoA:carbon dioxide ligase [H]

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MEDITARLADLEVRRARVMAGGGEERVARQHAAGKLTARERLELLLDPGSFLELDQFVRHRATDFGMQDIETPGEGVVTG
SGTINGRPVYVYAQDFTVMGGSLGEMHAAKICKVMDLALKTGVPVIGLNDSGGARIQEGVAALNGYGEIFRRNTHASGVI
PQIAAIMGPCAGGAVYSPGLMDFIFMVDNTAQMFITGPQVIKAVTGEEVSAEELGGAVTHATRSGVAHFRTPTEEDCLHL
IRTLLDYLPANNLEDPPFRPSSDPAERQNPNLAALVPVDPNKPYNVKEIIYGVVDDGLFLEIQGEYAANMVIGLARLAGY
TIGIVANQPQYLAGCLDINAADKAARFVRFCDAFNIPLLTLVDTPGYLPGVEQEQGGIIRHGAKLLYAFAEATVPKLTLV
LRKAYGGAYLAMCSRSLGADHVVAWPTAEIAVMGPEGAANIIFRQEISQADDPARVRQEKVAAYRDKFANPYVAAGLGLV
DAVIDPALTRPHLIRNLLTLLSKRESRPGKKHGNFPV

Sequences:

>Translated_517_residues
MEDITARLADLEVRRARVMAGGGEERVARQHAAGKLTARERLELLLDPGSFLELDQFVRHRATDFGMQDIETPGEGVVTG
SGTINGRPVYVYAQDFTVMGGSLGEMHAAKICKVMDLALKTGVPVIGLNDSGGARIQEGVAALNGYGEIFRRNTHASGVI
PQIAAIMGPCAGGAVYSPGLMDFIFMVDNTAQMFITGPQVIKAVTGEEVSAEELGGAVTHATRSGVAHFRTPTEEDCLHL
IRTLLDYLPANNLEDPPFRPSSDPAERQNPNLAALVPVDPNKPYNVKEIIYGVVDDGLFLEIQGEYAANMVIGLARLAGY
TIGIVANQPQYLAGCLDINAADKAARFVRFCDAFNIPLLTLVDTPGYLPGVEQEQGGIIRHGAKLLYAFAEATVPKLTLV
LRKAYGGAYLAMCSRSLGADHVVAWPTAEIAVMGPEGAANIIFRQEISQADDPARVRQEKVAAYRDKFANPYVAAGLGLV
DAVIDPALTRPHLIRNLLTLLSKRESRPGKKHGNFPV
>Mature_517_residues
MEDITARLADLEVRRARVMAGGGEERVARQHAAGKLTARERLELLLDPGSFLELDQFVRHRATDFGMQDIETPGEGVVTG
SGTINGRPVYVYAQDFTVMGGSLGEMHAAKICKVMDLALKTGVPVIGLNDSGGARIQEGVAALNGYGEIFRRNTHASGVI
PQIAAIMGPCAGGAVYSPGLMDFIFMVDNTAQMFITGPQVIKAVTGEEVSAEELGGAVTHATRSGVAHFRTPTEEDCLHL
IRTLLDYLPANNLEDPPFRPSSDPAERQNPNLAALVPVDPNKPYNVKEIIYGVVDDGLFLEIQGEYAANMVIGLARLAGY
TIGIVANQPQYLAGCLDINAADKAARFVRFCDAFNIPLLTLVDTPGYLPGVEQEQGGIIRHGAKLLYAFAEATVPKLTLV
LRKAYGGAYLAMCSRSLGADHVVAWPTAEIAVMGPEGAANIIFRQEISQADDPARVRQEKVAAYRDKFANPYVAAGLGLV
DAVIDPALTRPHLIRNLLTLLSKRESRPGKKHGNFPV

Specific function: This Protein Is A Component Of The Acetyl Coenzyme A Carboxylase Complex; First, Biotin Carboxylase Catalyzes The Carboxylation Of The Carrier Protein And Then The Transcarboxylase Transfers The Carboxyl Group To Form Malonyl-CoA. [C]

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=511, Percent_Identity=57.1428571428571, Blast_Score=585, Evalue=1e-167,
Organism=Homo sapiens, GI295821216, Length=531, Percent_Identity=54.9905838041431, Blast_Score=573, Evalue=1e-163,
Organism=Homo sapiens, GI11545863, Length=504, Percent_Identity=34.9206349206349, Blast_Score=259, Evalue=4e-69,
Organism=Homo sapiens, GI134142062, Length=391, Percent_Identity=24.2966751918159, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI38679960, Length=347, Percent_Identity=24.7838616714697, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI38679977, Length=347, Percent_Identity=24.7838616714697, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI38679967, Length=347, Percent_Identity=24.7838616714697, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI38679971, Length=343, Percent_Identity=24.7813411078717, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI38679974, Length=347, Percent_Identity=24.7838616714697, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI1788655, Length=189, Percent_Identity=27.5132275132275, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25147362, Length=503, Percent_Identity=56.6600397614314, Blast_Score=583, Evalue=1e-167,
Organism=Caenorhabditis elegans, GI25147359, Length=503, Percent_Identity=56.6600397614314, Blast_Score=583, Evalue=1e-167,
Organism=Caenorhabditis elegans, GI17552936, Length=509, Percent_Identity=34.1846758349705, Blast_Score=270, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI71997163, Length=395, Percent_Identity=21.7721518987342, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24586065, Length=520, Percent_Identity=33.2692307692308, Blast_Score=257, Evalue=2e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.3 [H]

Molecular weight: Translated: 55537; Mature: 55537

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDITARLADLEVRRARVMAGGGEERVARQHAAGKLTARERLELLLDPGSFLELDQFVRH
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHEEECCCCHHHHHHHHHH
RATDFGMQDIETPGEGVVTGSGTINGRPVYVYAQDFTVMGGSLGEMHAAKICKVMDLALK
HHHHCCCHHCCCCCCEEEECCCCCCCEEEEEEEECEEEECCCCHHHHHHHHHHHHHHHHH
TGVPVIGLNDSGGARIQEGVAALNGYGEIFRRNTHASGVIPQIAAIMGPCAGGAVYSPGL
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCH
MDFIFMVDNTAQMFITGPQVIKAVTGEEVSAEELGGAVTHATRSGVAHFRTPTEEDCLHL
HHHHHEECCCCEEEEECHHHHHHHCCCCCCHHHHCCHHHHHHHCCCHHCCCCCHHHHHHH
IRTLLDYLPANNLEDPPFRPSSDPAERQNPNLAALVPVDPNKPYNVKEIIYGVVDDGLFL
HHHHHHHCCCCCCCCCCCCCCCCCCHHCCCCEEEEEECCCCCCCCHHHHHHHHCCCCEEE
EIQGEYAANMVIGLARLAGYTIGIVANQPQYLAGCLDINAADKAARFVRFCDAFNIPLLT
EECCCHHHHHHHHHHHHCCEEEEEEECCCHHHEEEECCCCHHHHHHHHHHHHHCCCCEEE
LVDTPGYLPGVEQEQGGIIRHGAKLLYAFAEATVPKLTLVLRKAYGGAYLAMCSRSLGAD
EECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCC
HVVAWPTAEIAVMGPEGAANIIFRQEISQADDPARVRQEKVAAYRDKFANPYVAAGLGLV
CEEECCCCEEEEECCCCCCHHEEHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHH
DAVIDPALTRPHLIRNLLTLLSKRESRPGKKHGNFPV
HHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MEDITARLADLEVRRARVMAGGGEERVARQHAAGKLTARERLELLLDPGSFLELDQFVRH
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHEEECCCCHHHHHHHHHH
RATDFGMQDIETPGEGVVTGSGTINGRPVYVYAQDFTVMGGSLGEMHAAKICKVMDLALK
HHHHCCCHHCCCCCCEEEECCCCCCCEEEEEEEECEEEECCCCHHHHHHHHHHHHHHHHH
TGVPVIGLNDSGGARIQEGVAALNGYGEIFRRNTHASGVIPQIAAIMGPCAGGAVYSPGL
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCH
MDFIFMVDNTAQMFITGPQVIKAVTGEEVSAEELGGAVTHATRSGVAHFRTPTEEDCLHL
HHHHHEECCCCEEEEECHHHHHHHCCCCCCHHHHCCHHHHHHHCCCHHCCCCCHHHHHHH
IRTLLDYLPANNLEDPPFRPSSDPAERQNPNLAALVPVDPNKPYNVKEIIYGVVDDGLFL
HHHHHHHCCCCCCCCCCCCCCCCCCHHCCCCEEEEEECCCCCCCCHHHHHHHHCCCCEEE
EIQGEYAANMVIGLARLAGYTIGIVANQPQYLAGCLDINAADKAARFVRFCDAFNIPLLT
EECCCHHHHHHHHHHHHCCEEEEEEECCCHHHEEEECCCCHHHHHHHHHHHHHCCCCEEE
LVDTPGYLPGVEQEQGGIIRHGAKLLYAFAEATVPKLTLVLRKAYGGAYLAMCSRSLGAD
EECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCC
HVVAWPTAEIAVMGPEGAANIIFRQEISQADDPARVRQEKVAAYRDKFANPYVAAGLGLV
CEEECCCCEEEEECCCCCCHHEEHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHH
DAVIDPALTRPHLIRNLLTLLSKRESRPGKKHGNFPV
HHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8830278 [H]