Click here to switch to the map view.

The map label for this gene is thiL [H]

Identifier: 83590005

GI number: 83590005

Start: 1189739

End: 1190752

Strand: Reverse

Name: thiL [H]

Synonym: Moth_1157

Alternate gene names: 83590005

Gene position: 1190752-1189739 (Counterclockwise)

Preceding gene: 83590006

Following gene: 83590004

Centisome position: 45.3

GC content: 60.26

Gene sequence:

>1014_bases
TTGGAACTTAAAGAAGTAGGGGAATTTGGACTTATAGAACGCTTAAAGGCCGGGGCCATAGTGGACCCGGCCAGGGTAGT
TATGGGGATCGGTGATGACGCCGCCGTATTAAAGGGAGAACCTGGTTTCCTGACCCTGGCTTCGACGGATATGCTGGTGG
AGGATATCCACTTTACCTTGGCCACAGCTACCCCCCGGGAAATAGGTTATAAAACCATGGCTGTTAATGTCAGCGATATT
GCCGCCATGGGGGGGATACCAGAACAGGCCCTGGTATCCCTGGCTTTAAGGCCGGAGCAGCAGGTCGAGTTTGTGGACGA
GCTCTACGCCGGCCTGCGGGAATGTGGCCAGCGTTTTGGAGTAAATATAATTGGTGGCGACACGGTCTCTTCCCCCAGGG
CCATGGTAATCAACCTGGCCATATTGGGACGGGTGGAAAATGATGCCTGTCTCTACCGCCACGGTGCCCAGCCCGGGGAT
ATTCTGCTAGTAACCGGCGACCTGGGGGGCTCTGCCGCAGGTCTGGATACCCTGCTCAGTCCCCGCCCGGCCCCGGCGGA
GGTCATCGCCTGGGCCCGGGCACGCCACTTCCGGCCTACCCCGCGGGTAGTGGAAATCCGTGCCGCCCTGAAGGCCGGTG
GGCTCACGGCGGCCGATGACATCAGCGACGGCCTGGTAGCGGAGGTCTATACCCTGGCGACGGCTTCCAGGGTGGGAATA
GTCCTGGAGGCCGGGGCCATCCCCATCGCTCCGGCCACCCGGCAATTGGCGGCTATATACCATAAGGAGCCCCTGGATTA
CGCCCTTTATGGCGGCGAAGACTTTGAGCTCCTGCTGGCCTGCCGGCCGGATAAAGTAGACGCCGTTCGGGAAGCTGTGA
ACCGGGCCTGCAGGACGCCGGTGACGGTCATCGGCAGGGTCGTCCCGGCAGAAGAGGGTATTACCATAAACCACAGCGGC
CGAGTGCTACCCTTGACGCCAGGGGGTTATAACCACTTCCAGCTGGATAGATAA

Upstream 100 bases:

>100_bases
GAGAATACTTGTTCCTGCCGGCCGGTGTTAAAAACCTTGCACCGGCCCTTTACTTATGGCAAGATGGTAATAGCCTGGAA
AAGGAGTTGAGTAGCAAGCC

Downstream 100 bases:

>100_bases
CCCTGGGGCCCCTGATCTTTATCCGGGGGCGCTATGGCTGTAAGCAGTCAGCTGCGCAAGAATGAAAACTCCCGCTCGGT
TTCGTTTGCAGCCGGGACCA

Product: thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MELKEVGEFGLIERLKAGAIVDPARVVMGIGDDAAVLKGEPGFLTLASTDMLVEDIHFTLATATPREIGYKTMAVNVSDI
AAMGGIPEQALVSLALRPEQQVEFVDELYAGLRECGQRFGVNIIGGDTVSSPRAMVINLAILGRVENDACLYRHGAQPGD
ILLVTGDLGGSAAGLDTLLSPRPAPAEVIAWARARHFRPTPRVVEIRAALKAGGLTAADDISDGLVAEVYTLATASRVGI
VLEAGAIPIAPATRQLAAIYHKEPLDYALYGGEDFELLLACRPDKVDAVREAVNRACRTPVTVIGRVVPAEEGITINHSG
RVLPLTPGGYNHFQLDR

Sequences:

>Translated_337_residues
MELKEVGEFGLIERLKAGAIVDPARVVMGIGDDAAVLKGEPGFLTLASTDMLVEDIHFTLATATPREIGYKTMAVNVSDI
AAMGGIPEQALVSLALRPEQQVEFVDELYAGLRECGQRFGVNIIGGDTVSSPRAMVINLAILGRVENDACLYRHGAQPGD
ILLVTGDLGGSAAGLDTLLSPRPAPAEVIAWARARHFRPTPRVVEIRAALKAGGLTAADDISDGLVAEVYTLATASRVGI
VLEAGAIPIAPATRQLAAIYHKEPLDYALYGGEDFELLLACRPDKVDAVREAVNRACRTPVTVIGRVVPAEEGITINHSG
RVLPLTPGGYNHFQLDR
>Mature_337_residues
MELKEVGEFGLIERLKAGAIVDPARVVMGIGDDAAVLKGEPGFLTLASTDMLVEDIHFTLATATPREIGYKTMAVNVSDI
AAMGGIPEQALVSLALRPEQQVEFVDELYAGLRECGQRFGVNIIGGDTVSSPRAMVINLAILGRVENDACLYRHGAQPGD
ILLVTGDLGGSAAGLDTLLSPRPAPAEVIAWARARHFRPTPRVVEIRAALKAGGLTAADDISDGLVAEVYTLATASRVGI
VLEAGAIPIAPATRQLAAIYHKEPLDYALYGGEDFELLLACRPDKVDAVREAVNRACRTPVTVIGRVVPAEEGITINHSG
RVLPLTPGGYNHFQLDR

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=333, Percent_Identity=35.1351351351351, Blast_Score=143, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 35731; Mature: 35731

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKEVGEFGLIERLKAGAIVDPARVVMGIGDDAAVLKGEPGFLTLASTDMLVEDIHFTL
CCHHHHCCHHHHHHHHCCCCCCCCCEEEECCCCCEEEECCCCEEEEECCHHHHHHHEEEE
ATATPREIGYKTMAVNVSDIAAMGGIPEQALVSLALRPEQQVEFVDELYAGLRECGQRFG
EECCHHHHCCEEEEEEHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
VNIIGGDTVSSPRAMVINLAILGRVENDACLYRHGAQPGDILLVTGDLGGSAAGLDTLLS
CEEECCCCCCCCCEEEEEEEEEEEECCCEEEEECCCCCCCEEEEECCCCCCCCCHHHHCC
PRPAPAEVIAWARARHFRPTPRVVEIRAALKAGGLTAADDISDGLVAEVYTLATASRVGI
CCCCHHHHHHHHHHHCCCCCCCEEEEEEHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCEE
VLEAGAIPIAPATRQLAAIYHKEPLDYALYGGEDFELLLACRPDKVDAVREAVNRACRTP
EEECCCCCCCCCHHHHHHHHHCCCCCEEEECCCCEEEEEEECCCHHHHHHHHHHHHHCCC
VTVIGRVVPAEEGITINHSGRVLPLTPGGYNHFQLDR
HHHHHEEECCCCCEEECCCCEEEEECCCCCCCEEECC
>Mature Secondary Structure
MELKEVGEFGLIERLKAGAIVDPARVVMGIGDDAAVLKGEPGFLTLASTDMLVEDIHFTL
CCHHHHCCHHHHHHHHCCCCCCCCCEEEECCCCCEEEECCCCEEEEECCHHHHHHHEEEE
ATATPREIGYKTMAVNVSDIAAMGGIPEQALVSLALRPEQQVEFVDELYAGLRECGQRFG
EECCHHHHCCEEEEEEHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
VNIIGGDTVSSPRAMVINLAILGRVENDACLYRHGAQPGDILLVTGDLGGSAAGLDTLLS
CEEECCCCCCCCCEEEEEEEEEEEECCCEEEEECCCCCCCEEEEECCCCCCCCCHHHHCC
PRPAPAEVIAWARARHFRPTPRVVEIRAALKAGGLTAADDISDGLVAEVYTLATASRVGI
CCCCHHHHHHHHHHHCCCCCCCEEEEEEHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCEE
VLEAGAIPIAPATRQLAAIYHKEPLDYALYGGEDFELLLACRPDKVDAVREAVNRACRTP
EEECCCCCCCCCHHHHHHHHHCCCCCEEEECCCCEEEEEEECCCHHHHHHHHHHHHHCCC
VTVIGRVVPAEEGITINHSGRVLPLTPGGYNHFQLDR
HHHHHEEECCCCCEEECCCCEEEEECCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377; 8419296 [H]