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The map label for this gene is can [H]

Identifier: 83313340

GI number: 83313340

Start: 4648039

End: 4648698

Strand: Reverse

Name: can [H]

Synonym: amb4241

Alternate gene names: 83313340

Gene position: 4648698-4648039 (Counterclockwise)

Preceding gene: 83313341

Following gene: 83313339

Centisome position: 93.59

GC content: 64.55

Gene sequence:

>660_bases
ATGAGCAAAGTCCCGGGGATCGACCGCCTGCTGGCCAATAACAAGGCCTGGGCCGAGGAGACGGAGCGTACCAAGCCCGG
CTTCTTCGCCCATCTGGCAGAGCAGCAGACCCCGGGATATCTTTGGATCGGTTGCGCCGATTCCCGGGTTCCGGCCAACG
AGATCGTCGGCCTGGAACCCGGCGAGGTTTTCGTCCACCGCAACGTGGCCAATCAGGTCCACCATGCGGATATGAACTGT
CTGGCGGTGTTGCAATACGCCATCGACGTGCTCAAGGTGGAGCACATCATCGTCTGCGGCCATTACGGCTGCGGCGGGGT
GCGGGCGGCGTTGCAGGACGCCCGCCTGGGCGTCACCGAGTATTGGATCCGCCCGGTGCGCGACATCTGCGAATGCCACC
GCCACGAGTTGGACATGCTGCCCAACGAGGCGGCCCAGGTGGACCGGCTGTGCGAGCTGAACGTCATGCAGCAGGTGCGC
AACCTGTGCCGCTCGCCGGTGATCCAGGACGCCTGGCAGCGCGGCCAGCAACTGGAAGTGCATTCCTGGGTCTACGGCCT
GACCGACGGTCTGGTGCGGACCCTGGGCCCCACGGTGGCGGGGTTGAAGTCGCTGGATGAATTTGGCGCGTCCTATCTTA
TGCGTGGCGCGGCGTTTTAA

Upstream 100 bases:

>100_bases
AAAACATCCTGAAGGCCGAGCGCGACGCCACGGTCGCCAAGACCCATGCGGCCTCCGGTGATTCCCTGGCGGTGGACCAG
AAGATCATCGAGTTCGCCTC

Downstream 100 bases:

>100_bases
AAAACAGAAGGGAGAGGGACCATGAGCGAGTTCCCGAAGAAGAGCGTTTCCGATTGGGAAGCCCTGGCGTCGAAGGACCT
CAAGGGCGCCTCGCCCTCGA

Product: carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MSKVPGIDRLLANNKAWAEETERTKPGFFAHLAEQQTPGYLWIGCADSRVPANEIVGLEPGEVFVHRNVANQVHHADMNC
LAVLQYAIDVLKVEHIIVCGHYGCGGVRAALQDARLGVTEYWIRPVRDICECHRHELDMLPNEAAQVDRLCELNVMQQVR
NLCRSPVIQDAWQRGQQLEVHSWVYGLTDGLVRTLGPTVAGLKSLDEFGASYLMRGAAF

Sequences:

>Translated_219_residues
MSKVPGIDRLLANNKAWAEETERTKPGFFAHLAEQQTPGYLWIGCADSRVPANEIVGLEPGEVFVHRNVANQVHHADMNC
LAVLQYAIDVLKVEHIIVCGHYGCGGVRAALQDARLGVTEYWIRPVRDICECHRHELDMLPNEAAQVDRLCELNVMQQVR
NLCRSPVIQDAWQRGQQLEVHSWVYGLTDGLVRTLGPTVAGLKSLDEFGASYLMRGAAF
>Mature_218_residues
SKVPGIDRLLANNKAWAEETERTKPGFFAHLAEQQTPGYLWIGCADSRVPANEIVGLEPGEVFVHRNVANQVHHADMNCL
AVLQYAIDVLKVEHIIVCGHYGCGGVRAALQDARLGVTEYWIRPVRDICECHRHELDMLPNEAAQVDRLCELNVMQQVRN
LCRSPVIQDAWQRGQQLEVHSWVYGLTDGLVRTLGPTVAGLKSLDEFGASYLMRGAAF

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=201, Percent_Identity=53.7313432835821, Blast_Score=235, Evalue=2e-63,
Organism=Escherichia coli, GI1786534, Length=185, Percent_Identity=30.8108108108108, Blast_Score=84, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6324292, Length=204, Percent_Identity=33.8235294117647, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 24443; Mature: 24312

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVPGIDRLLANNKAWAEETERTKPGFFAHLAEQQTPGYLWIGCADSRVPANEIVGLEP
CCCCCCHHHHHHCCCHHHHHHHCCCCCHHHHHHHCCCCCEEEEECCCCCCCHHHCCCCCC
GEVFVHRNVANQVHHADMNCLAVLQYAIDVLKVEHIIVCGHYGCGGVRAALQDARLGVTE
CCEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHCCHHH
YWIRPVRDICECHRHELDMLPNEAAQVDRLCELNVMQQVRNLCRSPVIQDAWQRGQQLEV
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEH
HSWVYGLTDGLVRTLGPTVAGLKSLDEFGASYLMRGAAF
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKVPGIDRLLANNKAWAEETERTKPGFFAHLAEQQTPGYLWIGCADSRVPANEIVGLEP
CCCCCHHHHHHCCCHHHHHHHCCCCCHHHHHHHCCCCCEEEEECCCCCCCHHHCCCCCC
GEVFVHRNVANQVHHADMNCLAVLQYAIDVLKVEHIIVCGHYGCGGVRAALQDARLGVTE
CCEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHCCHHH
YWIRPVRDICECHRHELDMLPNEAAQVDRLCELNVMQQVRNLCRSPVIQDAWQRGQQLEV
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEH
HSWVYGLTDGLVRTLGPTVAGLKSLDEFGASYLMRGAAF
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]