Click here to switch to the map view.

The map label for this gene is nudL [H]

Identifier: 83313258

GI number: 83313258

Start: 4572785

End: 4573420

Strand: Reverse

Name: nudL [H]

Synonym: amb4159

Alternate gene names: 83313258

Gene position: 4573420-4572785 (Counterclockwise)

Preceding gene: 83313259

Following gene: 83313257

Centisome position: 92.07

GC content: 70.13

Gene sequence:

>636_bases
GTGATCGCGCGACGGCTGACCGACGGGTTCGACCCGGGCGGGCGCTCGGACTCGGCCCTGGAGGCCATGGTCCAGGGCGG
CGCCGTGCGCCCCGGCACCGCCACCACCGATGACAGCCTGACGCCGGCCGCCGTCCTGGTGCCGCTGGTGGAGCGCGCCG
AGGGCCTGACCGTGATGCTGACCAAGCGCACCGCCCATCTCGCCCACCATCCCGGCCAGATCAGCTTTCCCGGCGGGCGG
CTCGAACCCGAGGACCAGGGCGACTTCGCCACCTGCGCCTTGCGCGAAACCGAGGAGGAGACCGGCCTGTCCCGCCATCT
GGTCCGCCTGCTGGGCCGTCTGGACGACTACGCCACCGGGACCGGCTTCATCATTACGCCGCTGGTCGGCGTCATCGATC
CGCCCTTCACGCTGGCCCCCGATTCCTTCGAGGTGGCCGAGGTGTTCGAGGTGCCGCTGGCCTTCGTGCTGGACCAGGCC
AACCACCAGCTTCAAAGCCGCGAAGTCAGGGGCTTCCAGCGGCCGTTCTGGGCGCTGACCTGGGAAGACCGGCTGATCTG
GGGCGCCACCGCCGGAATCCTGGTCAACCTGTCGGAAGTGCTGGTTCCTCGCGAAACCGGCAGGACCTCGGAATGA

Upstream 100 bases:

>100_bases
GGTGGGAGGAGGACCGGGAGGGAGAAGCGGTTTACGGCCTATGGAGCAGCGGGAGCTTTTTTCCATTGGGGAGGCTGGAC
CTTCCCGACTGACGCGCGAG

Downstream 100 bases:

>100_bases
CCATGACCGTCATCCCGAGCGTAGGCGAGGGATCTCCGCTTGGCGCGCCGTTCCCGCGACGGAACCGCCGGTTCAGAATG
AGATTCCTCCTCCCGATGGT

Product: NTP pyrophosphohydrolase including oxidative damage repair enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MIARRLTDGFDPGGRSDSALEAMVQGGAVRPGTATTDDSLTPAAVLVPLVERAEGLTVMLTKRTAHLAHHPGQISFPGGR
LEPEDQGDFATCALRETEEETGLSRHLVRLLGRLDDYATGTGFIITPLVGVIDPPFTLAPDSFEVAEVFEVPLAFVLDQA
NHQLQSREVRGFQRPFWALTWEDRLIWGATAGILVNLSEVLVPRETGRTSE

Sequences:

>Translated_211_residues
MIARRLTDGFDPGGRSDSALEAMVQGGAVRPGTATTDDSLTPAAVLVPLVERAEGLTVMLTKRTAHLAHHPGQISFPGGR
LEPEDQGDFATCALRETEEETGLSRHLVRLLGRLDDYATGTGFIITPLVGVIDPPFTLAPDSFEVAEVFEVPLAFVLDQA
NHQLQSREVRGFQRPFWALTWEDRLIWGATAGILVNLSEVLVPRETGRTSE
>Mature_211_residues
MIARRLTDGFDPGGRSDSALEAMVQGGAVRPGTATTDDSLTPAAVLVPLVERAEGLTVMLTKRTAHLAHHPGQISFPGGR
LEPEDQGDFATCALRETEEETGLSRHLVRLLGRLDDYATGTGFIITPLVGVIDPPFTLAPDSFEVAEVFEVPLAFVLDQA
NHQLQSREVRGFQRPFWALTWEDRLIWGATAGILVNLSEVLVPRETGRTSE

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=171, Percent_Identity=33.9181286549708, Blast_Score=88, Evalue=5e-18,
Organism=Escherichia coli, GI1788115, Length=156, Percent_Identity=37.1794871794872, Blast_Score=80, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17536993, Length=133, Percent_Identity=36.8421052631579, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17510677, Length=122, Percent_Identity=34.4262295081967, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI18859683, Length=161, Percent_Identity=37.2670807453416, Blast_Score=83, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 22927; Mature: 22927

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIARRLTDGFDPGGRSDSALEAMVQGGAVRPGTATTDDSLTPAAVLVPLVERAEGLTVML
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEE
TKRTAHLAHHPGQISFPGGRLEPEDQGDFATCALRETEEETGLSRHLVRLLGRLDDYATG
ECCHHHHHCCCCEEECCCCCCCCCCCCCEEEEEEHHCHHHCCHHHHHHHHHHHHHCCCCC
TGFIITPLVGVIDPPFTLAPDSFEVAEVFEVPLAFVLDQANHQLQSREVRGFQRPFWALT
CCHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
WEDRLIWGATAGILVNLSEVLVPRETGRTSE
ECCEEEECCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MIARRLTDGFDPGGRSDSALEAMVQGGAVRPGTATTDDSLTPAAVLVPLVERAEGLTVML
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEE
TKRTAHLAHHPGQISFPGGRLEPEDQGDFATCALRETEEETGLSRHLVRLLGRLDDYATG
ECCHHHHHCCCCEEECCCCCCCCCCCCCEEEEEEHHCHHHCCHHHHHHHHHHHHHCCCCC
TGFIITPLVGVIDPPFTLAPDSFEVAEVFEVPLAFVLDQANHQLQSREVRGFQRPFWALT
CCHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
WEDRLIWGATAGILVNLSEVLVPRETGRTSE
ECCEEEECCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]