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The map label for this gene is clpP [H]

Identifier: 83311891

GI number: 83311891

Start: 2981186

End: 2981920

Strand: Reverse

Name: clpP [H]

Synonym: amb2792

Alternate gene names: 83311891

Gene position: 2981920-2981186 (Counterclockwise)

Preceding gene: 83311892

Following gene: 83311890

Centisome position: 60.03

GC content: 61.63

Gene sequence:

>735_bases
GTGCAAAGCCCGCGACATTCACCATATGAATGTCGCGGGCGGTCAACATCTTCGGCGTCCGCCCCCGCCGTTGCCATTGC
CAAAGGACGGAACATGCGCGAAAGAGACCCGATCGACCTCTACATGAACACCCTGGTTCCCATGGTGGTCGAGCAGACCA
ACCGGGGCGAGCGGTCCTACGACATCTATTCGCGCCTGCTGAAGGAGCGGATCATCTTCCTCACCGGACAGGTCTATGAC
GAAGTCGCCAGCCTGATCTGCGCCCAGCTGTTGTTCCTGGAATCCGAGAATCCCAGCAAGGACATCGCCTTCTACATCAA
TTCGCCGGGCGGCGTGGTGACCTCGGGTCTGGCCATCTACGACACCATGCAGTACATCCGCCCCAAGGTCTCCACCGTGT
GCATCGGCCAGGCGGCGTCCATGGGCTCGCTGCTGATGACCGCCGGCGAGAAGGGCAAGCGCTTTTCGCTGCCCAATTCC
CGCATCATGGTGCACCAGCCCTCGGGCGGGGCCCAGGGGCAGGCCACGGATATCGAAATCCAGGCCCGCGAGATCCTTGC
GCTGCGCGCCCGGCTCAACAATATCTACGTGGAGCACACCGGCCAGCCGCTGGATGTGATCGAAAAGGTGATGGAGCGCG
ACAAGTTCATGACCGCCGATGAAGCCAAGGAATTCGGCCTGATCGACGAGGTTGTGAACAAGCGTCCCGCCGTCGAGGAC
GATTCCGCCTCCTGA

Upstream 100 bases:

>100_bases
GACCCCGACGAGGCTTCCGCCGACGGCGAGGCCGCCCCGGCCAAGCCGAAGAAGAAGGCCGCCGCCAAGAAGAAGGCGGC
CGAATAGGTCCCGGTTTCAT

Downstream 100 bases:

>100_bases
GCCTGATCGGTTTCCGCGGCCGGGCCGGTCCCCCCAAGGGGACTTGCCCGGCCGTTTCCTTGTGCGGTCATGACAGAATT
GTCGTTGTCTGGCGTGGCGG

Product: protease subunit of ATP-dependent Clp protease

Products: NA

Alternate protein names: Endopeptidase Clp [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MQSPRHSPYECRGRSTSSASAPAVAIAKGRNMRERDPIDLYMNTLVPMVVEQTNRGERSYDIYSRLLKERIIFLTGQVYD
EVASLICAQLLFLESENPSKDIAFYINSPGGVVTSGLAIYDTMQYIRPKVSTVCIGQAASMGSLLMTAGEKGKRFSLPNS
RIMVHQPSGGAQGQATDIEIQAREILALRARLNNIYVEHTGQPLDVIEKVMERDKFMTADEAKEFGLIDEVVNKRPAVED
DSAS

Sequences:

>Translated_244_residues
MQSPRHSPYECRGRSTSSASAPAVAIAKGRNMRERDPIDLYMNTLVPMVVEQTNRGERSYDIYSRLLKERIIFLTGQVYD
EVASLICAQLLFLESENPSKDIAFYINSPGGVVTSGLAIYDTMQYIRPKVSTVCIGQAASMGSLLMTAGEKGKRFSLPNS
RIMVHQPSGGAQGQATDIEIQAREILALRARLNNIYVEHTGQPLDVIEKVMERDKFMTADEAKEFGLIDEVVNKRPAVED
DSAS
>Mature_244_residues
MQSPRHSPYECRGRSTSSASAPAVAIAKGRNMRERDPIDLYMNTLVPMVVEQTNRGERSYDIYSRLLKERIIFLTGQVYD
EVASLICAQLLFLESENPSKDIAFYINSPGGVVTSGLAIYDTMQYIRPKVSTVCIGQAASMGSLLMTAGEKGKRFSLPNS
RIMVHQPSGGAQGQATDIEIQAREILALRARLNNIYVEHTGQPLDVIEKVMERDKFMTADEAKEFGLIDEVVNKRPAVED
DSAS

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=197, Percent_Identity=64.4670050761421, Blast_Score=265, Evalue=4e-71,
Organism=Escherichia coli, GI1786641, Length=202, Percent_Identity=66.3366336633663, Blast_Score=291, Evalue=3e-80,
Organism=Caenorhabditis elegans, GI17538017, Length=196, Percent_Identity=59.1836734693878, Blast_Score=238, Evalue=3e-63,
Organism=Drosophila melanogaster, GI20129427, Length=192, Percent_Identity=63.0208333333333, Blast_Score=262, Evalue=2e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 27023; Mature: 27023

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00381 CLP_PROTEASE_SER ; PS00382 CLP_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSPRHSPYECRGRSTSSASAPAVAIAKGRNMRERDPIDLYMNTLVPMVVEQTNRGERSY
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHH
DIYSRLLKERIIFLTGQVYDEVASLICAQLLFLESENPSKDIAFYINSPGGVVTSGLAIY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHCCHHHH
DTMQYIRPKVSTVCIGQAASMGSLLMTAGEKGKRFSLPNSRIMVHQPSGGAQGQATDIEI
HHHHHHCCCHHEEEECCHHHHHHHHHHCCCCCCEECCCCCEEEEECCCCCCCCCCCEEEH
QAREILALRARLNNIYVEHTGQPLDVIEKVMERDKFMTADEAKEFGLIDEVVNKRPAVED
HHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHCCCCHHHHHHCCHHHHHHCCCCCCCC
DSAS
CCCC
>Mature Secondary Structure
MQSPRHSPYECRGRSTSSASAPAVAIAKGRNMRERDPIDLYMNTLVPMVVEQTNRGERSY
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHH
DIYSRLLKERIIFLTGQVYDEVASLICAQLLFLESENPSKDIAFYINSPGGVVTSGLAIY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHCCHHHH
DTMQYIRPKVSTVCIGQAASMGSLLMTAGEKGKRFSLPNSRIMVHQPSGGAQGQATDIEI
HHHHHHCCCHHEEEECCHHHHHHHHHHCCCCCCEECCCCCEEEEECCCCCCCCCCCEEEH
QAREILALRARLNNIYVEHTGQPLDVIEKVMERDKFMTADEAKEFGLIDEVVNKRPAVED
HHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHCCCCHHHHHHCCHHHHHHCCCCCCCC
DSAS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA