Click here to switch to the map view.

The map label for this gene is clpX

Identifier: 83311890

GI number: 83311890

Start: 2979762

End: 2981027

Strand: Reverse

Name: clpX

Synonym: amb2791

Alternate gene names: 83311890

Gene position: 2981027-2979762 (Counterclockwise)

Preceding gene: 83311891

Following gene: 83311889

Centisome position: 60.01

GC content: 63.67

Gene sequence:

>1266_bases
ATGACCAAGTCCACTAGCGGCGATTCCAAGAACACTCTGTACTGCTCGTTCTGCGGAAAGAGCCAGCACGAGGTGAGGAA
GCTCATCGCCGGGCCGACCGTGTTCATTTGCGATGAATGCGTCGAGCTGTGCATGGACATCATCCGCGAAGAGCACAAGA
CGCATCTGGTGCGTTCGCGCGATGGCGTGCCGACCCCCAAGGACATCTGCCAGGTGCTCGATGACTATGTCATCGGCCAG
AGCCATGCCAAGAAGGTGCTGTCGGTCGCCGTCCACAACCACTACAAGCGCCTGCAACACGGCGGCAAGAACAACGAAGT
GGAACTGGCCAAGTCCAACATCCTGCTGATCGGCCCCACCGGCTGCGGCAAGACCCTGCTGGCCCAGACCCTGGCCCGCA
TCCTGGACGTGCCGTTCACCATGGCCGACGCCACCACGCTGACCGAGGCCGGCTATGTGGGCGAGGATGTGGAGAACATC
ATCCTCAAGCTGCTGCAGGCTGCCGAATACAACGTGGAACGTGCCCAGCGCGGCATCGTCTACATCGACGAAGTGGACAA
GATCAGCCGCAAGTCCGACAACCCGTCCATCACCCGCGACGTGTCGGGCGAGGGTGTGCAGCAGGCCCTGCTGAAGATCA
TGGAAGGCACCGTCGCCTCGGTGCCGCCCCAGGGCGGACGCAAGCATCCCCAGCAGGAATTCCTGCAGGTGGATACCACC
AACATCCTGTTCATCTGCGGCGGCGCCTTCGCCGGGCTGGAAAAGATCATCGGCTCTCGCGGCCGGGGCACCTCCATCGG
CTTTGGCGCCGATGTGCGCGGCCCGGACGAGCGCCGCACGGGTGAAATCCTGCGCGAGGTCGAGCCCGAGGACCTGCTGA
AGTTCGGCCTGATCCCCGAATTCGTCGGCCGCCTGCCGGTGCTGGCGACGCTGGAGGATCTGGACGTGGATGCCCTGATC
GACATCCTGTCCAAGCCCAAGAACGCCCTGGTGAAGCAGTATCAGCGCCTGTTCGAGATGGAGGACACCCGTCTGGCCTT
CTCCGACGACGCGCTGAAGGCTATCGCCGAGAAGGCCATCGCCCGCAAGACCGGCGCGCGCGGCCTGCGCTCCATCATGG
AGACCATCCTGCTCGACACCATGTTCGACCTGCCCGGCCTCGACGCCGTGGACGAGGTGGTGATCAATAAGGAAGTGGTC
GAGGGCCGCGCCAAGCCGCTCTATATCTACGCCGAGCGCCGCGAGGACGTGGGGTCCAGCGCTTAA

Upstream 100 bases:

>100_bases
CTTGTGCGGTCATGACAGAATTGTCGTTGTCTGGCGTGGCGGGCTGTGTCTAACATGATTTCGCGGGTGCGGTGCGGCCC
CCTGATCCAATGGAGTTTCG

Downstream 100 bases:

>100_bases
GGTCCGCGGACACTTGGACAAGGCGGGGCGGGCTTCGGAAACGGGGTCCGCCTTTCGCTTTTCCTACAATTCCTAGTAGT
TCGCATGGCGTGGGGGGCAA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MTKSTSGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREEHKTHLVRSRDGVPTPKDICQVLDDYVIGQ
SHAKKVLSVAVHNHYKRLQHGGKNNEVELAKSNILLIGPTGCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENI
ILKLLQAAEYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
NILFICGGAFAGLEKIIGSRGRGTSIGFGADVRGPDERRTGEILREVEPEDLLKFGLIPEFVGRLPVLATLEDLDVDALI
DILSKPKNALVKQYQRLFEMEDTRLAFSDDALKAIAEKAIARKTGARGLRSIMETILLDTMFDLPGLDAVDEVVINKEVV
EGRAKPLYIYAERREDVGSSA

Sequences:

>Translated_421_residues
MTKSTSGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREEHKTHLVRSRDGVPTPKDICQVLDDYVIGQ
SHAKKVLSVAVHNHYKRLQHGGKNNEVELAKSNILLIGPTGCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENI
ILKLLQAAEYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
NILFICGGAFAGLEKIIGSRGRGTSIGFGADVRGPDERRTGEILREVEPEDLLKFGLIPEFVGRLPVLATLEDLDVDALI
DILSKPKNALVKQYQRLFEMEDTRLAFSDDALKAIAEKAIARKTGARGLRSIMETILLDTMFDLPGLDAVDEVVINKEVV
EGRAKPLYIYAERREDVGSSA
>Mature_420_residues
TKSTSGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREEHKTHLVRSRDGVPTPKDICQVLDDYVIGQS
HAKKVLSVAVHNHYKRLQHGGKNNEVELAKSNILLIGPTGCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENII
LKLLQAAEYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTN
ILFICGGAFAGLEKIIGSRGRGTSIGFGADVRGPDERRTGEILREVEPEDLLKFGLIPEFVGRLPVLATLEDLDVDALID
ILSKPKNALVKQYQRLFEMEDTRLAFSDDALKAIAEKAIARKTGARGLRSIMETILLDTMFDLPGLDAVDEVVINKEVVE
GRAKPLYIYAERREDVGSSA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=336, Percent_Identity=53.5714285714286, Blast_Score=326, Evalue=3e-89,
Organism=Escherichia coli, GI1786642, Length=417, Percent_Identity=70.9832134292566, Blast_Score=592, Evalue=1e-170,
Organism=Escherichia coli, GI1790366, Length=106, Percent_Identity=44.3396226415094, Blast_Score=96, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71982908, Length=328, Percent_Identity=46.3414634146341, Blast_Score=283, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI71982905, Length=328, Percent_Identity=46.3414634146341, Blast_Score=282, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI71988663, Length=393, Percent_Identity=37.9134860050891, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI71988660, Length=247, Percent_Identity=39.6761133603239, Blast_Score=167, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6319704, Length=418, Percent_Identity=39.2344497607655, Blast_Score=264, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24648289, Length=323, Percent_Identity=49.8452012383901, Blast_Score=305, Evalue=4e-83,
Organism=Drosophila melanogaster, GI24648291, Length=323, Percent_Identity=49.8452012383901, Blast_Score=305, Evalue=5e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_MAGSA (Q2W3I0)

Other databases:

- EMBL:   AP007255
- RefSeq:   YP_422154.1
- ProteinModelPortal:   Q2W3I0
- STRING:   Q2W3I0
- GeneID:   3803999
- GenomeReviews:   AP007255_GR
- KEGG:   mag:amb2791
- NMPDR:   fig|342108.5.peg.2478
- eggNOG:   COG1219
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- PhylomeDB:   Q2W3I0
- ProtClustDB:   PRK05342
- BioCyc:   MMAG342108:AMB2791-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 46260; Mature: 46128

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKSTSGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREEHKTHLVRSR
CCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DGVPTPKDICQVLDDYVIGQSHAKKVLSVAVHNHYKRLQHGGKNNEVELAKSNILLIGPT
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEEECC
GCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQAAEYNVERAQRGIV
CCCHHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCE
YIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
EEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHCCC
NILFICGGAFAGLEKIIGSRGRGTSIGFGADVRGPDERRTGEILREVEPEDLLKFGLIPE
CEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHCCCHH
FVGRLPVLATLEDLDVDALIDILSKPKNALVKQYQRLFEMEDTRLAFSDDALKAIAEKAI
HHCCCCHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHH
ARKTGARGLRSIMETILLDTMFDLPGLDAVDEVVINKEVVEGRAKPLYIYAERREDVGSS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCC
A
C
>Mature Secondary Structure 
TKSTSGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREEHKTHLVRSR
CCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DGVPTPKDICQVLDDYVIGQSHAKKVLSVAVHNHYKRLQHGGKNNEVELAKSNILLIGPT
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEEECC
GCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQAAEYNVERAQRGIV
CCCHHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCE
YIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
EEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHCCC
NILFICGGAFAGLEKIIGSRGRGTSIGFGADVRGPDERRTGEILREVEPEDLLKFGLIPE
CEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHCCCHH
FVGRLPVLATLEDLDVDALIDILSKPKNALVKQYQRLFEMEDTRLAFSDDALKAIAEKAI
HHCCCCHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHH
ARKTGARGLRSIMETILLDTMFDLPGLDAVDEVVINKEVVEGRAKPLYIYAERREDVGSS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA