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The map label for this gene is nuoC

Identifier: 83311884

GI number: 83311884

Start: 2972025

End: 2972624

Strand: Reverse

Name: nuoC

Synonym: amb2785

Alternate gene names: 83311884

Gene position: 2972624-2972025 (Counterclockwise)

Preceding gene: 83311885

Following gene: 83311883

Centisome position: 59.85

GC content: 64.17

Gene sequence:

>600_bases
ATGACGCAAGCGCTGAAGGATCTGGGTGAGTACATCGCCCAAGCCCTGCCCCAGGACGTGCTGGGAACCGAAGTGAACCG
CTGCGGCGAGCTGTCGCTCACCGTCAAGGCGGCCTCCATCGTCAAGGTGATGACCTACCTCAAGGACGACGCCGGCTGTC
TGTTCAAGCAGCTGGTGGATGTGTGCGGCGTGGACTGGCCCGGGCGCGAGCAGCGCTTCGACGTGGTCTACCACCTGCTG
TCCATGAAGCATAACCAGCGGGTCCGCGTGAAGGTGGCCACCGACGAGGAGACCGCCGTTCCCTCCGTCACCGGCGTGTT
CAGCTCGGCCGGCTGGTTCGAGCGTGAAGTGTGGGACATGTACGGCGTGCTGTTCTCGGACCATCCCGACCTGCGCCGCA
TCCTCACCGATTACGGTTTCGAGGGGCACCCGCTGCGCAAGGACTTCCCGCTGACCGGCTATGTGGAGATGCGCTACGAC
GACGAGACCAAGCGCGTGGTCTACGAGCCGGTGAAGCTGACCCAGGATTTCCGCAGCTTTGACTTCCTGTCGCCCTGGGA
AGGGCCGGGGATGCTGCCCGGCGATGAGAAGGCGAACTGA

Upstream 100 bases:

>100_bases
CCCTCGGCGGAAGCGCTGATGTACGGCATCCTGCAGCTGCAGAAGAAGATCCGCCGCACCGGCTCCATCCTCCGATAGCG
CCGAAGAGGGATTCTCGAAG

Downstream 100 bases:

>100_bases
CATGGCCGAATCCCAGATCCAGAGCTACACCATCAACTTCGGGCCGCAGCATCCGGCGGCCCACGGCGTGCTGCGCCTGA
TCCTCGAGATGTCGGGCGAG

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MTQALKDLGEYIAQALPQDVLGTEVNRCGELSLTVKAASIVKVMTYLKDDAGCLFKQLVDVCGVDWPGREQRFDVVYHLL
SMKHNQRVRVKVATDEETAVPSVTGVFSSAGWFEREVWDMYGVLFSDHPDLRRILTDYGFEGHPLRKDFPLTGYVEMRYD
DETKRVVYEPVKLTQDFRSFDFLSPWEGPGMLPGDEKAN

Sequences:

>Translated_199_residues
MTQALKDLGEYIAQALPQDVLGTEVNRCGELSLTVKAASIVKVMTYLKDDAGCLFKQLVDVCGVDWPGREQRFDVVYHLL
SMKHNQRVRVKVATDEETAVPSVTGVFSSAGWFEREVWDMYGVLFSDHPDLRRILTDYGFEGHPLRKDFPLTGYVEMRYD
DETKRVVYEPVKLTQDFRSFDFLSPWEGPGMLPGDEKAN
>Mature_198_residues
TQALKDLGEYIAQALPQDVLGTEVNRCGELSLTVKAASIVKVMTYLKDDAGCLFKQLVDVCGVDWPGREQRFDVVYHLLS
MKHNQRVRVKVATDEETAVPSVTGVFSSAGWFEREVWDMYGVLFSDHPDLRRILTDYGFEGHPLRKDFPLTGYVEMRYDD
ETKRVVYEPVKLTQDFRSFDFLSPWEGPGMLPGDEKAN

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=186, Percent_Identity=55.3763440860215, Blast_Score=231, Evalue=3e-61,
Organism=Escherichia coli, GI145693162, Length=140, Percent_Identity=36.4285714285714, Blast_Score=95, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71990788, Length=185, Percent_Identity=51.3513513513513, Blast_Score=206, Evalue=7e-54,
Organism=Caenorhabditis elegans, GI32563621, Length=185, Percent_Identity=51.3513513513513, Blast_Score=206, Evalue=8e-54,
Organism=Drosophila melanogaster, GI24656494, Length=195, Percent_Identity=53.3333333333333, Blast_Score=224, Evalue=3e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_MAGSA (Q2W3I6)

Other databases:

- EMBL:   AP007255
- RefSeq:   YP_422148.1
- ProteinModelPortal:   Q2W3I6
- SMR:   Q2W3I6
- STRING:   Q2W3I6
- GeneID:   3803875
- GenomeReviews:   AP007255_GR
- KEGG:   mag:amb2785
- NMPDR:   fig|342108.5.peg.2472
- eggNOG:   COG0852
- HOGENOM:   HBG727675
- OMA:   VVYEPVR
- ProtClustDB:   PRK06074
- BioCyc:   MMAG342108:AMB2785-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 22692; Mature: 22561

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQALKDLGEYIAQALPQDVLGTEVNRCGELSLTVKAASIVKVMTYLKDDAGCLFKQLVD
CCHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHH
VCGVDWPGREQRFDVVYHLLSMKHNQRVRVKVATDEETAVPSVTGVFSSAGWFEREVWDM
HHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHH
YGVLFSDHPDLRRILTDYGFEGHPLRKDFPLTGYVEMRYDDETKRVVYEPVKLTQDFRSF
HHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHC
DFLSPWEGPGMLPGDEKAN
CCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TQALKDLGEYIAQALPQDVLGTEVNRCGELSLTVKAASIVKVMTYLKDDAGCLFKQLVD
CHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHH
VCGVDWPGREQRFDVVYHLLSMKHNQRVRVKVATDEETAVPSVTGVFSSAGWFEREVWDM
HHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHH
YGVLFSDHPDLRRILTDYGFEGHPLRKDFPLTGYVEMRYDDETKRVVYEPVKLTQDFRSF
HHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHC
DFLSPWEGPGMLPGDEKAN
CCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA