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The map label for this gene is nuoD

Identifier: 83311883

GI number: 83311883

Start: 2970845

End: 2972023

Strand: Reverse

Name: nuoD

Synonym: amb2784

Alternate gene names: 83311883

Gene position: 2972023-2970845 (Counterclockwise)

Preceding gene: 83311884

Following gene: 83311882

Centisome position: 59.83

GC content: 62.51

Gene sequence:

>1179_bases
ATGGCCGAATCCCAGATCCAGAGCTACACCATCAACTTCGGGCCGCAGCATCCGGCGGCCCACGGCGTGCTGCGCCTGAT
CCTCGAGATGTCGGGCGAGGTCGTCGACCGCGCCGACCCCCATGTGGGCCTGCTGCATCGCGGCACCGAGAAGCTGATCG
AGCACAAGACCTACCTGCAGGCGACGCCCTATTTCGATCGCCTCGACTATGTGGGCACCATGAACCAGGAGCATGCCTTC
GTGCTGGCCACGGAGAAGCTGCTGGGCATCGACATTCCCATCCGCGCCAAATTCATCCGGACGCTCTACGATGAAATCGG
CCGCATCCTGAACCATCTGCTCAACGTCACCGCGTTCATCTTCGACGTGGGCGGCATGACTCCGCTGCTCTACGGCTTCG
AAGAGCGCGAGAAGCTGATGGAATTCTACGAGCGCGTCTGCGGCGCCCGTCTGCACGCCAATTACTACCGTCCGGGCGGC
GTCGCCGCCGACCTGCCGGCCGGTCTGCTGGAAGACATCGCCGCCTGGTGCGAGACCTTCCCCAAGGTTCTGGACGACAT
CGAGACCCTGGCCACCGACAACCGCATCTTCAAGCAGCGCGTGGTCGATATCGGCGTGGTCAGCCCGGAGCAGGCCCTGG
ACTGGGGCTTCACCGGCCCCAACCTGCGCGCCTCCGGCATCGCCTGGGATCTGCGCAAATCTCAGCCCTACGACGTCTAC
GACCAGATGGAATTCGACATTCCGGTGGGCAAGAACGGTGACGGCTATGACCGTTATCTCGTCCGCGTGCTGGAAATGCG
CGAATCGGTCAAGATCATGAAGCAGTGCATCGCCAAGATGCCTGGCGGTCCGGTCCGGGTCGAGGACAACAAGATCACGC
CGCCCAAGCGGTCCGAGATGAAGACCTCCATGGAATCGCTGATCCATCACTTCAAGCTGTTCACCGAGGGCTTCAAGGTC
CCGGCCGGCGAAGTGTACGGGGCCATCGAGGCGCCCAAGGGCGAGTTCGCCGTCTATCTGGTTTCCGACGGCACCGGCAA
GCCCTACCGCTGCAAGATCCGTCCGCCGGGATATGTTCACCTGCAGGCGCTCGACATGATGTCCAAGGGACACATGCTGG
CCGACGTGGTGGCCAATATCGGCTCCATCGACATCGTTTTCGGCGAGATCGACCGATGA

Upstream 100 bases:

>100_bases
TACGAGCCGGTGAAGCTGACCCAGGATTTCCGCAGCTTTGACTTCCTGTCGCCCTGGGAAGGGCCGGGGATGCTGCCCGG
CGATGAGAAGGCGAACTGAC

Downstream 100 bases:

>100_bases
GCAATCATTCCTACGAACCGGAAAGCTTCGCTTTCACCCCCGAATACCTGGAGAAGGCCAAGGCCTTCGTCGCCAAGTAC
CCGGTTGGCCGCCAGCAGAG

Product: NADH dehydrogenase subunit D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit D; NDH-1 subunit D

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MAESQIQSYTINFGPQHPAAHGVLRLILEMSGEVVDRADPHVGLLHRGTEKLIEHKTYLQATPYFDRLDYVGTMNQEHAF
VLATEKLLGIDIPIRAKFIRTLYDEIGRILNHLLNVTAFIFDVGGMTPLLYGFEEREKLMEFYERVCGARLHANYYRPGG
VAADLPAGLLEDIAAWCETFPKVLDDIETLATDNRIFKQRVVDIGVVSPEQALDWGFTGPNLRASGIAWDLRKSQPYDVY
DQMEFDIPVGKNGDGYDRYLVRVLEMRESVKIMKQCIAKMPGGPVRVEDNKITPPKRSEMKTSMESLIHHFKLFTEGFKV
PAGEVYGAIEAPKGEFAVYLVSDGTGKPYRCKIRPPGYVHLQALDMMSKGHMLADVVANIGSIDIVFGEIDR

Sequences:

>Translated_392_residues
MAESQIQSYTINFGPQHPAAHGVLRLILEMSGEVVDRADPHVGLLHRGTEKLIEHKTYLQATPYFDRLDYVGTMNQEHAF
VLATEKLLGIDIPIRAKFIRTLYDEIGRILNHLLNVTAFIFDVGGMTPLLYGFEEREKLMEFYERVCGARLHANYYRPGG
VAADLPAGLLEDIAAWCETFPKVLDDIETLATDNRIFKQRVVDIGVVSPEQALDWGFTGPNLRASGIAWDLRKSQPYDVY
DQMEFDIPVGKNGDGYDRYLVRVLEMRESVKIMKQCIAKMPGGPVRVEDNKITPPKRSEMKTSMESLIHHFKLFTEGFKV
PAGEVYGAIEAPKGEFAVYLVSDGTGKPYRCKIRPPGYVHLQALDMMSKGHMLADVVANIGSIDIVFGEIDR
>Mature_391_residues
AESQIQSYTINFGPQHPAAHGVLRLILEMSGEVVDRADPHVGLLHRGTEKLIEHKTYLQATPYFDRLDYVGTMNQEHAFV
LATEKLLGIDIPIRAKFIRTLYDEIGRILNHLLNVTAFIFDVGGMTPLLYGFEEREKLMEFYERVCGARLHANYYRPGGV
AADLPAGLLEDIAAWCETFPKVLDDIETLATDNRIFKQRVVDIGVVSPEQALDWGFTGPNLRASGIAWDLRKSQPYDVYD
QMEFDIPVGKNGDGYDRYLVRVLEMRESVKIMKQCIAKMPGGPVRVEDNKITPPKRSEMKTSMESLIHHFKLFTEGFKVP
AGEVYGAIEAPKGEFAVYLVSDGTGKPYRCKIRPPGYVHLQALDMMSKGHMLADVVANIGSIDIVFGEIDR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758786, Length=390, Percent_Identity=65.1282051282051, Blast_Score=539, Evalue=1e-153,
Organism=Homo sapiens, GI260898743, Length=384, Percent_Identity=64.5833333333333, Blast_Score=525, Evalue=1e-149,
Organism=Escherichia coli, GI145693162, Length=383, Percent_Identity=39.686684073107, Blast_Score=314, Evalue=6e-87,
Organism=Escherichia coli, GI1789076, Length=387, Percent_Identity=26.3565891472868, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI1788832, Length=396, Percent_Identity=27.7777777777778, Blast_Score=112, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17568379, Length=390, Percent_Identity=62.0512820512821, Blast_Score=526, Evalue=1e-150,
Organism=Caenorhabditis elegans, GI17555284, Length=390, Percent_Identity=62.0512820512821, Blast_Score=523, Evalue=1e-149,
Organism=Drosophila melanogaster, GI24638644, Length=390, Percent_Identity=62.8205128205128, Blast_Score=540, Evalue=1e-154,
Organism=Drosophila melanogaster, GI221459469, Length=390, Percent_Identity=60.2564102564103, Blast_Score=508, Evalue=1e-144,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOD_MAGSA (Q2W3I7)

Other databases:

- EMBL:   AP007255
- RefSeq:   YP_422147.1
- HSSP:   Q56220
- ProteinModelPortal:   Q2W3I7
- SMR:   Q2W3I7
- STRING:   Q2W3I7
- GeneID:   3803874
- GenomeReviews:   AP007255_GR
- KEGG:   mag:amb2784
- NMPDR:   fig|342108.5.peg.2471
- eggNOG:   COG0649
- HOGENOM:   HBG459705
- OMA:   IFYERAC
- PhylomeDB:   Q2W3I7
- ProtClustDB:   PRK06075
- BioCyc:   MMAG342108:AMB2784-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01358
- InterPro:   IPR010219
- InterPro:   IPR001135
- InterPro:   IPR014029
- InterPro:   IPR022885
- TIGRFAMs:   TIGR01962

Pfam domain/function: PF00346 Complex1_49kDa

EC number: =1.6.99.5

Molecular weight: Translated: 44097; Mature: 43966

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS00535 COMPLEX1_49K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAESQIQSYTINFGPQHPAAHGVLRLILEMSGEVVDRADPHVGLLHRGTEKLIEHKTYLQ
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCHHHCCCCCEEHHHCCHHHHHHHHHHHC
ATPYFDRLDYVGTMNQEHAFVLATEKLLGIDIPIRAKFIRTLYDEIGRILNHLLNVTAFI
CCCCHHHHHHHCCCCCCCEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FDVGGMTPLLYGFEEREKLMEFYERVCGARLHANYYRPGGVAADLPAGLLEDIAAWCETF
HHHCCCHHHHHCHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
PKVLDDIETLATDNRIFKQRVVDIGVVSPEQALDWGFTGPNLRASGIAWDLRKSQPYDVY
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHCCCCCCCCCEECCEEEECCCCCCCCCH
DQMEFDIPVGKNGDGYDRYLVRVLEMRESVKIMKQCIAKMPGGPVRVEDNKITPPKRSEM
HCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHH
KTSMESLIHHFKLFTEGFKVPAGEVYGAIEAPKGEFAVYLVSDGTGKPYRCKIRPPGYVH
HHHHHHHHHHHHHHHHCCCCCCHHHHCCEECCCCCEEEEEEECCCCCCEEEEECCCCEEE
LQALDMMSKGHMLADVVANIGSIDIVFGEIDR
EHHHHHHHCCCHHHHHHHCCCCEEEEEECCCC
>Mature Secondary Structure 
AESQIQSYTINFGPQHPAAHGVLRLILEMSGEVVDRADPHVGLLHRGTEKLIEHKTYLQ
CCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCHHHCCCCCEEHHHCCHHHHHHHHHHHC
ATPYFDRLDYVGTMNQEHAFVLATEKLLGIDIPIRAKFIRTLYDEIGRILNHLLNVTAFI
CCCCHHHHHHHCCCCCCCEEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FDVGGMTPLLYGFEEREKLMEFYERVCGARLHANYYRPGGVAADLPAGLLEDIAAWCETF
HHHCCCHHHHHCHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
PKVLDDIETLATDNRIFKQRVVDIGVVSPEQALDWGFTGPNLRASGIAWDLRKSQPYDVY
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHCCCCCCCCCEECCEEEECCCCCCCCCH
DQMEFDIPVGKNGDGYDRYLVRVLEMRESVKIMKQCIAKMPGGPVRVEDNKITPPKRSEM
HCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHH
KTSMESLIHHFKLFTEGFKVPAGEVYGAIEAPKGEFAVYLVSDGTGKPYRCKIRPPGYVH
HHHHHHHHHHHHHHHHCCCCCCHHHHCCEECCCCCEEEEEEECCCCCCEEEEECCCCEEE
LQALDMMSKGHMLADVVANIGSIDIVFGEIDR
EHHHHHHHCCCHHHHHHHCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA