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The map label for this gene is coaX

Identifier: 83311871

GI number: 83311871

Start: 2957934

End: 2958716

Strand: Reverse

Name: coaX

Synonym: amb2772

Alternate gene names: 83311871

Gene position: 2958716-2957934 (Counterclockwise)

Preceding gene: 83311872

Following gene: 83311870

Centisome position: 59.57

GC content: 65.64

Gene sequence:

>783_bases
ATGCTGTTGGCCATCGATTCGGGCAACACCAATATCGTCTTCGCGGTCTATGACGGCGACACCCTGCGCGGCGAGTGGCG
TGCCTCGACGGATTCCGAGCGGACCGCCGACGAACTGGGCGTCTGGCTCACCCAGTTGCTGACCATCGAGGGGCTGAACC
GCCTGGACATCTCGGCGGCGATCATCGCCAGCGTGGTGCCGGCCATGGTGTTCGGCCTGAAGACCCTGTGCCGCCGCTAT
TTCAAGTGCGAGCCGCTGGTGGTGGGCGACGAAGGGGTGGATCTAGGCCTGTCCATCCTGCTCGATCGTCCCGAGGAAGT
GGGCGCCGACCGCCTGGTCAATGCCGTGGCGGCCCATAAATATTACAAGGGGCCGTTGATCGTCATCGACTTCGGCACGG
CCACCACCTTCGACGTGGTGGACGCGGACGGAAATTACTGCGGCGGGGCCATCTCGCCCGGCATCAATCTGTCGCTGGAG
GCCCTGCACATGGCGGCCGCCAAGCTGCCGCGGGTGGCTATCGGGCGGCCACGGCAGGTGATCGGGCGGGCCACGGTGCC
GGCCATGCAATCGGGGATCTTCTGGGGCTATGTCGGCCTGATCGAGGGATTGGTGAAGCGGATCAAGGAAGAGTTCGGCT
CGGACATGCTGGTGCTGGCCACCGGCGGACTGGCGCCGCTGTTTGCCGAGGCGACCAAGGTGATCAACGCGCTGGACGCC
GACCTGACCCTGCGCGGCCTGCTGGAAATCCATCGCCGCAATTCGACGCCGGTGCGGGGATGA

Upstream 100 bases:

>100_bases
CGACGAGGAAGGCGGTCTGCTGCTCGATCAGGGCGAGGCCGGAATCCGGCGGGTTCTGGCTGGGGATGTGTTTTTTCCGG
GATTGTGACGGAGCTTTTCC

Downstream 100 bases:

>100_bases
GCCAGGGCGAACTCCTCTTCCTGCCCCTGGGGGGCGTCGGCGAGATCGGCATGAATCTCGCGCTGTACGGCTATGACGGC
AAGTGGCTGATGGTCGATTG

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MLLAIDSGNTNIVFAVYDGDTLRGEWRASTDSERTADELGVWLTQLLTIEGLNRLDISAAIIASVVPAMVFGLKTLCRRY
FKCEPLVVGDEGVDLGLSILLDRPEEVGADRLVNAVAAHKYYKGPLIVIDFGTATTFDVVDADGNYCGGAISPGINLSLE
ALHMAAAKLPRVAIGRPRQVIGRATVPAMQSGIFWGYVGLIEGLVKRIKEEFGSDMLVLATGGLAPLFAEATKVINALDA
DLTLRGLLEIHRRNSTPVRG

Sequences:

>Translated_260_residues
MLLAIDSGNTNIVFAVYDGDTLRGEWRASTDSERTADELGVWLTQLLTIEGLNRLDISAAIIASVVPAMVFGLKTLCRRY
FKCEPLVVGDEGVDLGLSILLDRPEEVGADRLVNAVAAHKYYKGPLIVIDFGTATTFDVVDADGNYCGGAISPGINLSLE
ALHMAAAKLPRVAIGRPRQVIGRATVPAMQSGIFWGYVGLIEGLVKRIKEEFGSDMLVLATGGLAPLFAEATKVINALDA
DLTLRGLLEIHRRNSTPVRG
>Mature_260_residues
MLLAIDSGNTNIVFAVYDGDTLRGEWRASTDSERTADELGVWLTQLLTIEGLNRLDISAAIIASVVPAMVFGLKTLCRRY
FKCEPLVVGDEGVDLGLSILLDRPEEVGADRLVNAVAAHKYYKGPLIVIDFGTATTFDVVDADGNYCGGAISPGINLSLE
ALHMAAAKLPRVAIGRPRQVIGRATVPAMQSGIFWGYVGLIEGLVKRIKEEFGSDMLVLATGGLAPLFAEATKVINALDA
DLTLRGLLEIHRRNSTPVRG

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_MAGSA (Q2W3J9)

Other databases:

- EMBL:   AP007255
- RefSeq:   YP_422135.1
- ProteinModelPortal:   Q2W3J9
- SMR:   Q2W3J9
- STRING:   Q2W3J9
- GeneID:   3803862
- GenomeReviews:   AP007255_GR
- KEGG:   mag:amb2772
- NMPDR:   fig|342108.5.peg.2459
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   PAIVVDF
- ProtClustDB:   PRK13318
- BioCyc:   MMAG342108:AMB2772-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 27880; Mature: 27880

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: ACT_SITE 110-110 BINDING 133-133 BINDING 185-185

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLAIDSGNTNIVFAVYDGDTLRGEWRASTDSERTADELGVWLTQLLTIEGLNRLDISAA
CEEEEECCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHH
IIASVVPAMVFGLKTLCRRYFKCEPLVVGDEGVDLGLSILLDRPEEVGADRLVNAVAAHK
HHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCEEEECCCHHCCHHHHHHHHHHHH
YYKGPLIVIDFGTATTFDVVDADGNYCGGAISPGINLSLEALHMAAAKLPRVAIGRPRQV
HCCCCEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHCCCCHHH
IGRATVPAMQSGIFWGYVGLIEGLVKRIKEEFGSDMLVLATGGLAPLFAEATKVINALDA
HHCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCC
DLTLRGLLEIHRRNSTPVRG
CHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLLAIDSGNTNIVFAVYDGDTLRGEWRASTDSERTADELGVWLTQLLTIEGLNRLDISAA
CEEEEECCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHH
IIASVVPAMVFGLKTLCRRYFKCEPLVVGDEGVDLGLSILLDRPEEVGADRLVNAVAAHK
HHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCEEEECCCHHCCHHHHHHHHHHHH
YYKGPLIVIDFGTATTFDVVDADGNYCGGAISPGINLSLEALHMAAAKLPRVAIGRPRQV
HCCCCEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHCCCCHHH
IGRATVPAMQSGIFWGYVGLIEGLVKRIKEEFGSDMLVLATGGLAPLFAEATKVINALDA
HHCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCC
DLTLRGLLEIHRRNSTPVRG
CHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA