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The map label for this gene is frr

Identifier: 83311594

GI number: 83311594

Start: 2672799

End: 2673371

Strand: Reverse

Name: frr

Synonym: amb2495

Alternate gene names: 83311594

Gene position: 2673371-2672799 (Counterclockwise)

Preceding gene: 83311595

Following gene: 83311593

Centisome position: 53.82

GC content: 61.26

Gene sequence:

>573_bases
GTGTCCGCTCCGACCAACTGGAACGACCTCAAGAAGGACATCACCCGGCGCATGGACAGTGCCGTCGAGGTGCTGAAGAA
GGAATTCTCGGGCCTGCGCTCGGGCCGTGCCTCCATCAACCTGCTGGACCCGGTCGTGGTCGAGGCCTATGGCCAGACCA
TGCCGCTCAGCCAGTGTGGCACCGTCGGTGTTCCCGAGCCGCGCATGCTGACCGTCCAGGTGTGGGACAAGTCCCAGGTC
AAGGCCGTGGAAAAGGCTATCGCCAATGCCGGTCTCGGTCTCAATCCCCAGGCCGACGGCCAGATGATCCGCGTGCCGAT
TCCGCCGCTGAACGAGGAGCGCCGCAAGGAGCTGCAGAAGGTGGCCGGCAAGTACTCCGAACAGGCCCGCATCTCCGTGC
GCAACGTGCGCCGTGACGGCATGGACACCTTGAAGAAGATGGAAAAGGACGGCCACATCTCCGAGGACGAGATCAAGAAG
CACGAAAAAGAGATCCAGGCCATCACCGACGAGACCATCAAGAAGATCGACGAGGCCTTGGGTCACAAGGAAAAGGAAAT
CATGCAGGTTTGA

Upstream 100 bases:

>100_bases
TTCGACCTGCACCGGCCCGGCGCCTTCGCCGAAACGGTCTCGGGACGCGGCCTGTTCACCATCATCGCCAACGACTAATA
AGCCTTAAGGGGAGTCGATC

Downstream 100 bases:

>100_bases
GGAGGCGAGGACCCGGTATGGAGCCCATGCTTTCCCCCGCCGACCAGCCGCCGCCGCCGGTGCACGTGGCCATCATCATG
GATGGCAACGGGCGCTGGGC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MSAPTNWNDLKKDITRRMDSAVEVLKKEFSGLRSGRASINLLDPVVVEAYGQTMPLSQCGTVGVPEPRMLTVQVWDKSQV
KAVEKAIANAGLGLNPQADGQMIRVPIPPLNEERRKELQKVAGKYSEQARISVRNVRRDGMDTLKKMEKDGHISEDEIKK
HEKEIQAITDETIKKIDEALGHKEKEIMQV

Sequences:

>Translated_190_residues
MSAPTNWNDLKKDITRRMDSAVEVLKKEFSGLRSGRASINLLDPVVVEAYGQTMPLSQCGTVGVPEPRMLTVQVWDKSQV
KAVEKAIANAGLGLNPQADGQMIRVPIPPLNEERRKELQKVAGKYSEQARISVRNVRRDGMDTLKKMEKDGHISEDEIKK
HEKEIQAITDETIKKIDEALGHKEKEIMQV
>Mature_189_residues
SAPTNWNDLKKDITRRMDSAVEVLKKEFSGLRSGRASINLLDPVVVEAYGQTMPLSQCGTVGVPEPRMLTVQVWDKSQVK
AVEKAIANAGLGLNPQADGQMIRVPIPPLNEERRKELQKVAGKYSEQARISVRNVRRDGMDTLKKMEKDGHISEDEIKKH
EKEIQAITDETIKKIDEALGHKEKEIMQV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=177, Percent_Identity=33.8983050847458, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI291042689, Length=148, Percent_Identity=35.1351351351351, Blast_Score=88, Evalue=4e-18,
Organism=Escherichia coli, GI1786368, Length=183, Percent_Identity=50.2732240437158, Blast_Score=182, Evalue=9e-48,
Organism=Drosophila melanogaster, GI24661488, Length=176, Percent_Identity=26.7045454545455, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_MAGSA (Q2W4C6)

Other databases:

- EMBL:   AP007255
- RefSeq:   YP_421858.1
- ProteinModelPortal:   Q2W4C6
- SMR:   Q2W4C6
- STRING:   Q2W4C6
- GeneID:   3803212
- GenomeReviews:   AP007255_GR
- KEGG:   mag:amb2495
- NMPDR:   fig|342108.5.peg.2195
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   Q2W4C6
- ProtClustDB:   PRK00083
- BioCyc:   MMAG342108:AMB2495-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 21342; Mature: 21211

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPTNWNDLKKDITRRMDSAVEVLKKEFSGLRSGRASINLLDPVVVEAYGQTMPLSQCG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHCC
TVGVPEPRMLTVQVWDKSQVKAVEKAIANAGLGLNPQADGQMIRVPIPPLNEERRKELQK
CCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHH
VAGKYSEQARISVRNVRRDGMDTLKKMEKDGHISEDEIKKHEKEIQAITDETIKKIDEAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GHKEKEIMQV
CCCHHHHHCC
>Mature Secondary Structure 
SAPTNWNDLKKDITRRMDSAVEVLKKEFSGLRSGRASINLLDPVVVEAYGQTMPLSQCG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHCC
TVGVPEPRMLTVQVWDKSQVKAVEKAIANAGLGLNPQADGQMIRVPIPPLNEERRKELQK
CCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHH
VAGKYSEQARISVRNVRRDGMDTLKKMEKDGHISEDEIKKHEKEIQAITDETIKKIDEAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GHKEKEIMQV
CCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA