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The map label for this gene is fabZ

Identifier: 83311586

GI number: 83311586

Start: 2664397

End: 2664882

Strand: Reverse

Name: fabZ

Synonym: amb2487

Alternate gene names: 83311586

Gene position: 2664882-2664397 (Counterclockwise)

Preceding gene: 83311587

Following gene: 83311585

Centisome position: 53.65

GC content: 59.47

Gene sequence:

>486_bases
GTGAGTATGGATACCGCCAACAACGACCAGGGCACCGACCTGGGCAAGGTTATCGACATCAGCCGGATCATCCAGATGAT
TCCGCACCGCTATCCCTTCCTCATGGTGGATCGGGTGGTACAGGTGGTGGCCAATGAAAGCGCCGTGGGCATCAAGAACG
TCACCATCAACGAGCCGTTCTTCCAGGGCCACTTTCCGTCGCGTCCGGTCTTTCCGGGGGTGTTGATCATCGAATCCATG
GCCCAGACGGCGGCCGTGCTGGTGGTCGAGACTTTGGGCGAATCGGCGGAAGGCAAGCTGGTCTACTTCATGAGCGTCGA
GAACTGCCGGTTCCGCAAACCGGTCGGTCCCGGCGATCAGCTGATGATTCACGTCTTCAAGGAACGCTCGCGCGGGAACG
TCTGGAAGTTCCGTGGCGAAGCCAAGGTCGATGGCGTCCTTGTCGCCGAAGCCACCTACGCCGCCATGATTCTGGACGAG
AAATGA

Upstream 100 bases:

>100_bases
CTGTCGGCGGCGCGCCCGCCGTGCCCATGGCGGATTGGCTGCGCCAGTCGGCCATTCTGGGCAAGATGGCGCGAAAAAAG
AGTTAGGCCAAAGGCAGGAC

Downstream 100 bases:

>100_bases
CCAATATTCACCCTTCGGCCGTTATCGATTCCAAGGCGGAGATCGCCTCTTCGGCGATCATCGGGCCTTTCTGCGTGGTT
GGACCCGACGTCAAGTTGGG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: trans-Delta2-enoyl-acyl-ACP; H2O [C]

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MSMDTANNDQGTDLGKVIDISRIIQMIPHRYPFLMVDRVVQVVANESAVGIKNVTINEPFFQGHFPSRPVFPGVLIIESM
AQTAAVLVVETLGESAEGKLVYFMSVENCRFRKPVGPGDQLMIHVFKERSRGNVWKFRGEAKVDGVLVAEATYAAMILDE
K

Sequences:

>Translated_161_residues
MSMDTANNDQGTDLGKVIDISRIIQMIPHRYPFLMVDRVVQVVANESAVGIKNVTINEPFFQGHFPSRPVFPGVLIIESM
AQTAAVLVVETLGESAEGKLVYFMSVENCRFRKPVGPGDQLMIHVFKERSRGNVWKFRGEAKVDGVLVAEATYAAMILDE
K
>Mature_160_residues
SMDTANNDQGTDLGKVIDISRIIQMIPHRYPFLMVDRVVQVVANESAVGIKNVTINEPFFQGHFPSRPVFPGVLIIESMA
QTAAVLVVETLGESAEGKLVYFMSVENCRFRKPVGPGDQLMIHVFKERSRGNVWKFRGEAKVDGVLVAEATYAAMILDEK

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=136, Percent_Identity=46.3235294117647, Blast_Score=147, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_MAGSA (Q2W4D4)

Other databases:

- EMBL:   AP007255
- RefSeq:   YP_421850.1
- ProteinModelPortal:   Q2W4D4
- SMR:   Q2W4D4
- STRING:   Q2W4D4
- GeneID:   3804692
- GenomeReviews:   AP007255_GR
- KEGG:   mag:amb2487
- NMPDR:   fig|342108.5.peg.2188
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- PhylomeDB:   Q2W4D4
- ProtClustDB:   PRK00006
- BioCyc:   MMAG342108:AMB2487-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.- [C]

Molecular weight: Translated: 17885; Mature: 17754

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: ACT_SITE 64-64

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMDTANNDQGTDLGKVIDISRIIQMIPHRYPFLMVDRVVQVVANESAVGIKNVTINEPF
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCC
FQGHFPSRPVFPGVLIIESMAQTAAVLVVETLGESAEGKLVYFMSVENCRFRKPVGPGDQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEECCCCCCCHH
LMIHVFKERSRGNVWKFRGEAKVDGVLVAEATYAAMILDEK
EEHEEEHHCCCCCEEEEECCCCCCEEEEECCEEEEEEEECC
>Mature Secondary Structure 
SMDTANNDQGTDLGKVIDISRIIQMIPHRYPFLMVDRVVQVVANESAVGIKNVTINEPF
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCC
FQGHFPSRPVFPGVLIIESMAQTAAVLVVETLGESAEGKLVYFMSVENCRFRKPVGPGDQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEECCCCCCCHH
LMIHVFKERSRGNVWKFRGEAKVDGVLVAEATYAAMILDEK
EEHEEEHHCCCCCEEEEECCCCCCEEEEECCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-3-hydroxy-acyl-ACP [C]

Specific reaction: D-3-hydroxy-acyl-ACP = trans-Delta2-enoyl-acyl-ACP + H2O [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA