Click here to switch to the map view.

The map label for this gene is eamA [H]

Identifier: 83309959

GI number: 83309959

Start: 918907

End: 919812

Strand: Reverse

Name: eamA [H]

Synonym: amb0860

Alternate gene names: 83309959

Gene position: 919812-918907 (Counterclockwise)

Preceding gene: 83309960

Following gene: 83309958

Centisome position: 18.52

GC content: 69.65

Gene sequence:

>906_bases
ATGGCCATGACCGCCCCCTCGCGCCTCACGCCCCTGGAATGGGCCTCGGCCACCCTGGTGGTCACCCTGTGGGGCCTCAA
TTTCGTGGCGGTGAAGACGGCCTTGGGCACCTTGCCGCCCTTCCTGCTGACCGCCTTGCGCTTCGCCTGCACCGCGCTGA
TCCTGGCGCCGTTCTTCCGCCCCAGCCGCGCCCAGTTGCCCGGCATCCTCCTGCTGGCCCTGTTGCTGGGGGTCGGGCAT
TTCGGCCTGATGTTCTTCGGTGTCGCCGGCATGGACGCCGCCACCGCCGCCATCGTCATCGAGCTGTCCATTCCCTTCTC
CGCCATCCTGGCCTGGGCCTTCTTCGGCGAGGTGCTGGGAGTCTGGCGCAGCCTGGGGCTGGCGGTGTCGTTCATCGGCG
TCGCCCTGCTGGCCGGCGAGCCCCACCTGCCCCGCCTCACGCCGTTCATCGCCGTGGTGGCCTCGGGCTTCGCCTGGGCC
TTGGCCAATGTGGTGATCAAGCGCTTAGGCGCCATCAATCCCCTGGCGCTGAACGGTTGGATGGCCATGCTGGCCTCGCC
CTTGCTGCTGGGCCTGTCGCTGGCGACGGAAAGCGGGCAGATGGAGGCGCTGGCCGCCACCGGGATCAAGGGCTGGAGCG
GCGTGGCCTACACCATCGTCGGCTCGACCCTGATCGCCTATACTCTGTGGTATCGCCTGATCGCCCGTCACCCCATGAAC
CGGGTGGTGCCCTTCACCCTGCTGGGGCCGGTGGTGGGGCTGGCCGGTGGCGTGCTGCTGCTGGGCGAGCCGCTGACCTG
GCACAAGCTGGTGGGCGGCGCCCTGACCGTGCTGGGCGTCGCCGTGGTGGAACTGCTGCCCGGCCGCGCCATCCACCGTG
CGGAAGAACCGGAGCCCGGAACATGA

Upstream 100 bases:

>100_bases
CGAAGCTCGTGCCTGAAAGATCCTTCGCCTATGGCTCAGGATGACATGGAGAGGTGCGCTCCATGACCCCCTCCTTCCGG
AGCGCGGGCGTCCCGCCCGC

Downstream 100 bases:

>100_bases
CCATCATTTCCCGCCCCTCGCCCAATTTCGAGCCGCGCCCGGCCGGGGCCATCGTCGACACCCTGGTGCTGCACTATACC
GGCATGGAATCGGGCGAGGC

Product: DMT family permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MAMTAPSRLTPLEWASATLVVTLWGLNFVAVKTALGTLPPFLLTALRFACTALILAPFFRPSRAQLPGILLLALLLGVGH
FGLMFFGVAGMDAATAAIVIELSIPFSAILAWAFFGEVLGVWRSLGLAVSFIGVALLAGEPHLPRLTPFIAVVASGFAWA
LANVVIKRLGAINPLALNGWMAMLASPLLLGLSLATESGQMEALAATGIKGWSGVAYTIVGSTLIAYTLWYRLIARHPMN
RVVPFTLLGPVVGLAGGVLLLGEPLTWHKLVGGALTVLGVAVVELLPGRAIHRAEEPEPGT

Sequences:

>Translated_301_residues
MAMTAPSRLTPLEWASATLVVTLWGLNFVAVKTALGTLPPFLLTALRFACTALILAPFFRPSRAQLPGILLLALLLGVGH
FGLMFFGVAGMDAATAAIVIELSIPFSAILAWAFFGEVLGVWRSLGLAVSFIGVALLAGEPHLPRLTPFIAVVASGFAWA
LANVVIKRLGAINPLALNGWMAMLASPLLLGLSLATESGQMEALAATGIKGWSGVAYTIVGSTLIAYTLWYRLIARHPMN
RVVPFTLLGPVVGLAGGVLLLGEPLTWHKLVGGALTVLGVAVVELLPGRAIHRAEEPEPGT
>Mature_300_residues
AMTAPSRLTPLEWASATLVVTLWGLNFVAVKTALGTLPPFLLTALRFACTALILAPFFRPSRAQLPGILLLALLLGVGHF
GLMFFGVAGMDAATAAIVIELSIPFSAILAWAFFGEVLGVWRSLGLAVSFIGVALLAGEPHLPRLTPFIAVVASGFAWAL
ANVVIKRLGAINPLALNGWMAMLASPLLLGLSLATESGQMEALAATGIKGWSGVAYTIVGSTLIAYTLWYRLIARHPMNR
VVPFTLLGPVVGLAGGVLLLGEPLTWHKLVGGALTVLGVAVVELLPGRAIHRAEEPEPGT

Specific function: May be an export pump for cysteine and other metabolites of the cysteine pathway (such as N-acetyl-L-serine (NAS) and O- acetyl-L-serine (OAS)), and for other amino acids and their metabolites [H]

COG id: COG0697

COG function: function code GER; Permeases of the drug/metabolite transporter (DMT) superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DUF6 domains [H]

Homologues:

Organism=Escherichia coli, GI87081929, Length=276, Percent_Identity=30.4347826086957, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000620 [H]

Pfam domain/function: PF00892 DUF6 [H]

EC number: NA

Molecular weight: Translated: 31525; Mature: 31394

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMTAPSRLTPLEWASATLVVTLWGLNFVAVKTALGTLPPFLLTALRFACTALILAPFFR
CCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
PSRAQLPGILLLALLLGVGHFGLMFFGVAGMDAATAAIVIELSIPFSAILAWAFFGEVLG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEEECCCHHHHHHHHHHHHHHH
VWRSLGLAVSFIGVALLAGEPHLPRLTPFIAVVASGFAWALANVVIKRLGAINPLALNGW
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
MAMLASPLLLGLSLATESGQMEALAATGIKGWSGVAYTIVGSTLIAYTLWYRLIARHPMN
HHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHH
RVVPFTLLGPVVGLAGGVLLLGEPLTWHKLVGGALTVLGVAVVELLPGRAIHRAEEPEPG
HCCHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCC
T
C
>Mature Secondary Structure 
AMTAPSRLTPLEWASATLVVTLWGLNFVAVKTALGTLPPFLLTALRFACTALILAPFFR
CCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
PSRAQLPGILLLALLLGVGHFGLMFFGVAGMDAATAAIVIELSIPFSAILAWAFFGEVLG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEEECCCHHHHHHHHHHHHHHH
VWRSLGLAVSFIGVALLAGEPHLPRLTPFIAVVASGFAWALANVVIKRLGAINPLALNGW
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
MAMLASPLLLGLSLATESGQMEALAATGIKGWSGVAYTIVGSTLIAYTLWYRLIARHPMN
HHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHH
RVVPFTLLGPVVGLAGGVLLLGEPLTWHKLVGGALTVLGVAVVELLPGRAIHRAEEPEPG
HCCHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCC
T
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8383113; 9097039; 9278503; 10844694 [H]