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The map label for this gene is uup [H]

Identifier: 83309960

GI number: 83309960

Start: 919966

End: 921480

Strand: Reverse

Name: uup [H]

Synonym: amb0861

Alternate gene names: 83309960

Gene position: 921480-919966 (Counterclockwise)

Preceding gene: 83309964

Following gene: 83309959

Centisome position: 18.55

GC content: 69.57

Gene sequence:

>1515_bases
ATGTATCGGGTCGACGCGGTACTGGATGCCGTGGGCATCGACGGCGCCCGCGACCCCGTGGCGCTGTCGGGTGGCGAGGG
ACGCCGGGCCGCCCTGGCCCGCGCCCTGGTGGGCCAGCCCGACGCCCTGCTGCTGGACGAGCCCACCAACCATCTGGACC
TGCCCACCATCTTGTGGCTGGAGGAATGGCTGTCGTCCTATGGCGGCGCCCTGGTGATGATCAGCCACGACCGCCGCTTC
CTGGAGACGGTGTCGAAACAGACCCTGTGGCTGGAGCGGGGCGTGGTGCGCCGCGCCGAGTTCGGCTTCGAGAAGTTCCC
CGCCTGGCAGGACGAGGTCTTCGCCGCCGAGGAGGCGGAGCTGGCCCGCATGAATACCCGCATGCGCCAGGAGATGCACT
GGCTGGCACGCGGCGTCACGGCGCGCCGCAAGCGCAACATGGGCCGCCTCAGGGCCTTGCAGGGCCTGCGCAGCGAGCGG
GCCGAGCGCAAGTCCCAGGTGCTGGCCGCCGGCCGTCAGGTCAATCTGGCCACGGATTCCGGCGACCTGTCCGGCCGCCT
GGTGATCGAGGCGGAAAACGTCACCAAGGCGTTCGGCGACAAGCGCATCTGCCAGGATTTCTCCACCCGCATCCTGCGCG
GCGACCGGGTGGGGCTGATCGGCCCCAACGGCGCCGGCAAGACCACGCTGCTGCGCATGCTGACCGGGGAACTGGCCCCC
GATGGCGGCGTGGTGCGCCTAGGGACCAATCTGGAGACCGCCTATTTTGACCAGCGCCGCGCCGCGCTCGACCCCGACAA
GAGCGTCTGGGACACCCTGACCGACGGCCGCGGCGACAATGTCTGGGTGCGGGGCACCCCCCAGCACGTGGTCGGCTACA
TGAAAGACTTCCTGTTCTCCGAGGCCCAGGCCCGCACCCCGGTCCGCGCCCTGTCGGGCGGCGAGCGCAACCGCCTGCTG
CTGGCAAAGCTGCTGGCCAAGCCCTCCAACCTGCTGATCCTGGACGAGCCGACCAACGATCTCGACATGGAGACCCTGGA
CCTGCTGGAAGAGGTGCTGGCCGATTACGACGGCACCCTGCTGGTGGTCAGCCACGACCGCGACTTCCTCGACCGTCTGG
TGACCAGCGTCATCGCCGTGGAGGGCGACGCAGAGGTCTCGGAATATGTGGGCGGCTATTCGGACTATCTGCGCCAGCGG
CCCGCCAAGCCGGCCAATGCCGCGCCCAAGCCGCCTTCCAAGCCCCAGGCCCAGCCTAAGCCCCAAAGCGCCCGCACCCG
CCTGTCCTACAACGAGCAGCGGGAACTGGACCAGCTTCCCAGCCGCATCGATAAACTGACGGCGGAGATCGCCAAGCTGG
AGACCGACCTGGCCGATCCCGCCCTCTATGCCAAGGATGCCGCCCGCTTCCAGACGCTGGCCGCCCGCGCCGAGGCGGCC
CGCGCCGAGCTGGATGACGCCGAGGTACGCTGGCTGGAGCTGGAGGCCAAGCGGGAAGAGGCGGGGGGGAAGTGA

Upstream 100 bases:

>100_bases
CGGCGCCTCCATCGCCGTGCTGCCCCAGGACCCCATCATCCTGGCCCCCACCATCGCCGACTATGTGGCGCAAGGATTGC
CGCCCGCCGAGCGCGACCAG

Downstream 100 bases:

>100_bases
CCGTGCAAGATGTCATGCTGAGCGCCAGCGAAGCATCTTTCACCCGTGATGCCCGAAGCTCGTGCCTGAAAGATCCTTCG
CCTATGGCTCAGGATGACAT

Product: ABC transporter ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MYRVDAVLDAVGIDGARDPVALSGGEGRRAALARALVGQPDALLLDEPTNHLDLPTILWLEEWLSSYGGALVMISHDRRF
LETVSKQTLWLERGVVRRAEFGFEKFPAWQDEVFAAEEAELARMNTRMRQEMHWLARGVTARRKRNMGRLRALQGLRSER
AERKSQVLAAGRQVNLATDSGDLSGRLVIEAENVTKAFGDKRICQDFSTRILRGDRVGLIGPNGAGKTTLLRMLTGELAP
DGGVVRLGTNLETAYFDQRRAALDPDKSVWDTLTDGRGDNVWVRGTPQHVVGYMKDFLFSEAQARTPVRALSGGERNRLL
LAKLLAKPSNLLILDEPTNDLDMETLDLLEEVLADYDGTLLVVSHDRDFLDRLVTSVIAVEGDAEVSEYVGGYSDYLRQR
PAKPANAAPKPPSKPQAQPKPQSARTRLSYNEQRELDQLPSRIDKLTAEIAKLETDLADPALYAKDAARFQTLAARAEAA
RAELDDAEVRWLELEAKREEAGGK

Sequences:

>Translated_504_residues
MYRVDAVLDAVGIDGARDPVALSGGEGRRAALARALVGQPDALLLDEPTNHLDLPTILWLEEWLSSYGGALVMISHDRRF
LETVSKQTLWLERGVVRRAEFGFEKFPAWQDEVFAAEEAELARMNTRMRQEMHWLARGVTARRKRNMGRLRALQGLRSER
AERKSQVLAAGRQVNLATDSGDLSGRLVIEAENVTKAFGDKRICQDFSTRILRGDRVGLIGPNGAGKTTLLRMLTGELAP
DGGVVRLGTNLETAYFDQRRAALDPDKSVWDTLTDGRGDNVWVRGTPQHVVGYMKDFLFSEAQARTPVRALSGGERNRLL
LAKLLAKPSNLLILDEPTNDLDMETLDLLEEVLADYDGTLLVVSHDRDFLDRLVTSVIAVEGDAEVSEYVGGYSDYLRQR
PAKPANAAPKPPSKPQAQPKPQSARTRLSYNEQRELDQLPSRIDKLTAEIAKLETDLADPALYAKDAARFQTLAARAEAA
RAELDDAEVRWLELEAKREEAGGK
>Mature_504_residues
MYRVDAVLDAVGIDGARDPVALSGGEGRRAALARALVGQPDALLLDEPTNHLDLPTILWLEEWLSSYGGALVMISHDRRF
LETVSKQTLWLERGVVRRAEFGFEKFPAWQDEVFAAEEAELARMNTRMRQEMHWLARGVTARRKRNMGRLRALQGLRSER
AERKSQVLAAGRQVNLATDSGDLSGRLVIEAENVTKAFGDKRICQDFSTRILRGDRVGLIGPNGAGKTTLLRMLTGELAP
DGGVVRLGTNLETAYFDQRRAALDPDKSVWDTLTDGRGDNVWVRGTPQHVVGYMKDFLFSEAQARTPVRALSGGERNRLL
LAKLLAKPSNLLILDEPTNDLDMETLDLLEEVLADYDGTLLVVSHDRDFLDRLVTSVIAVEGDAEVSEYVGGYSDYLRQR
PAKPANAAPKPPSKPQAQPKPQSARTRLSYNEQRELDQLPSRIDKLTAEIAKLETDLADPALYAKDAARFQTLAARAEAA
RAELDDAEVRWLELEAKREEAGGK

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=386, Percent_Identity=31.6062176165803, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI10947137, Length=393, Percent_Identity=29.7709923664122, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI27881506, Length=393, Percent_Identity=29.7709923664122, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI10947135, Length=409, Percent_Identity=28.8508557457213, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI69354671, Length=409, Percent_Identity=28.8508557457213, Blast_Score=137, Evalue=3e-32,
Organism=Escherichia coli, GI1787182, Length=498, Percent_Identity=45.7831325301205, Blast_Score=401, Evalue=1e-113,
Organism=Escherichia coli, GI2367384, Length=375, Percent_Identity=38.9333333333333, Blast_Score=261, Evalue=8e-71,
Organism=Escherichia coli, GI1789751, Length=524, Percent_Identity=31.4885496183206, Blast_Score=216, Evalue=4e-57,
Organism=Escherichia coli, GI1787041, Length=385, Percent_Identity=32.987012987013, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1788165, Length=189, Percent_Identity=34.9206349206349, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87081791, Length=197, Percent_Identity=31.4720812182741, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1790739, Length=210, Percent_Identity=30.4761904761905, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788225, Length=207, Percent_Identity=27.536231884058, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788761, Length=199, Percent_Identity=29.1457286432161, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787758, Length=208, Percent_Identity=27.8846153846154, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1786253, Length=192, Percent_Identity=32.2916666666667, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787712, Length=199, Percent_Identity=29.1457286432161, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789672, Length=205, Percent_Identity=27.3170731707317, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87081709, Length=206, Percent_Identity=28.1553398058252, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87081782, Length=204, Percent_Identity=29.9019607843137, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787164, Length=178, Percent_Identity=30.8988764044944, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790467, Length=167, Percent_Identity=29.3413173652695, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI48994943, Length=284, Percent_Identity=26.7605633802817, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17555318, Length=366, Percent_Identity=30.327868852459, Blast_Score=144, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI17559834, Length=401, Percent_Identity=26.4339152119701, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17553372, Length=405, Percent_Identity=28.3950617283951, Blast_Score=132, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6321121, Length=400, Percent_Identity=30, Blast_Score=150, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6320874, Length=381, Percent_Identity=26.7716535433071, Blast_Score=140, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6324314, Length=207, Percent_Identity=35.2657004830918, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6323278, Length=211, Percent_Identity=30.8056872037915, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6325030, Length=262, Percent_Identity=30.1526717557252, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24642252, Length=413, Percent_Identity=32.2033898305085, Blast_Score=179, Evalue=6e-45,
Organism=Drosophila melanogaster, GI18859989, Length=413, Percent_Identity=32.2033898305085, Blast_Score=179, Evalue=6e-45,
Organism=Drosophila melanogaster, GI24666836, Length=409, Percent_Identity=30.0733496332518, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24641342, Length=413, Percent_Identity=29.0556900726392, Blast_Score=160, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 55932; Mature: 55932

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRVDAVLDAVGIDGARDPVALSGGEGRRAALARALVGQPDALLLDEPTNHLDLPTILWL
CEEHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHH
EEWLSSYGGALVMISHDRRFLETVSKQTLWLERGVVRRAEFGFEKFPAWQDEVFAAEEAE
HHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHH
LARMNTRMRQEMHWLARGVTARRKRNMGRLRALQGLRSERAERKSQVLAAGRQVNLATDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
GDLSGRLVIEAENVTKAFGDKRICQDFSTRILRGDRVGLIGPNGAGKTTLLRMLTGELAP
CCCCCEEEEEECHHHHHHCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCC
DGGVVRLGTNLETAYFDQRRAALDPDKSVWDTLTDGRGDNVWVRGTPQHVVGYMKDFLFS
CCCEEEECCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHH
EAQARTPVRALSGGERNRLLLAKLLAKPSNLLILDEPTNDLDMETLDLLEEVLADYDGTL
HHHHCCCHHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEE
LVVSHDRDFLDRLVTSVIAVEGDAEVSEYVGGYSDYLRQRPAKPANAAPKPPSKPQAQPK
EEEECCHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCC
PQSARTRLSYNEQRELDQLPSRIDKLTAEIAKLETDLADPALYAKDAARFQTLAARAEAA
CHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
RAELDDAEVRWLELEAKREEAGGK
HHCCCCCCEEEEEEEHHHHCCCCC
>Mature Secondary Structure
MYRVDAVLDAVGIDGARDPVALSGGEGRRAALARALVGQPDALLLDEPTNHLDLPTILWL
CEEHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHH
EEWLSSYGGALVMISHDRRFLETVSKQTLWLERGVVRRAEFGFEKFPAWQDEVFAAEEAE
HHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHH
LARMNTRMRQEMHWLARGVTARRKRNMGRLRALQGLRSERAERKSQVLAAGRQVNLATDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
GDLSGRLVIEAENVTKAFGDKRICQDFSTRILRGDRVGLIGPNGAGKTTLLRMLTGELAP
CCCCCEEEEEECHHHHHHCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCC
DGGVVRLGTNLETAYFDQRRAALDPDKSVWDTLTDGRGDNVWVRGTPQHVVGYMKDFLFS
CCCEEEECCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHH
EAQARTPVRALSGGERNRLLLAKLLAKPSNLLILDEPTNDLDMETLDLLEEVLADYDGTL
HHHHCCCHHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEE
LVVSHDRDFLDRLVTSVIAVEGDAEVSEYVGGYSDYLRQRPAKPANAAPKPPSKPQAQPK
EEEECCHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCC
PQSARTRLSYNEQRELDQLPSRIDKLTAEIAKLETDLADPALYAKDAARFQTLAARAEAA
CHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
RAELDDAEVRWLELEAKREEAGGK
HHCCCCCCEEEEEEEHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 9139905; 7751275 [H]