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The map label for this gene is icaB

Identifier: 82752246

GI number: 82752246

Start: 2698855

End: 2699727

Strand: Direct

Name: icaB

Synonym: SAB2543

Alternate gene names: 82752246

Gene position: 2698855-2699727 (Clockwise)

Preceding gene: 82752245

Following gene: 82752247

Centisome position: 98.41

GC content: 29.32

Gene sequence:

>873_bases
GTGAAGTATAGAAAATTAATAATTTTAGTGCTGAGTATCTTGATCATATTGCCTGTAAGCACACTGGATGGTCATCATAT
TGCAAATGCAGATGACGATCCACCTAAAAAACTGAAATATAAAGAAAATAGTGCTCTGGCATTAAATTATCACCGTGTAA
GAAAAGCGAATTTTCTGAATAATTTTCTTTACTTCTTTTCTAGTAGTAAAGAAATTAAAAATTATAGTGTTAGTCAATCA
CAATTTGAATCTCAAATAAAATGGCTAAAATCACATGATGCTAAATTTTTAACCTTGAAAGAATTTTTATATTACAAGAA
AAAAGGTAAGTTTCCAAAACGAAGTGTATGGATTAACTTTGATGATATGGATGAAACTATTTATGAAAATGCTTATCCAA
TCTTAAAAAAATATAAAATACCGGCAACTGGGTTTATTATCACAGGTCATGTTGGGGAAGAAAACTTTCACAACCTCGAT
ATGATTAGTAAAAAAGAACTAAAAGAAATGTATAAAACTGGTTTATGGGAATTTGAAACACATACCCACGATTTGCATAA
CTTATCTAAAAATAATAAGTCAAAATTAATGAAAGCTTCTGAAGCTACAATCATAAAAGATTTAAACAAAAGTGAAAAAT
ATCTAACTAAAAACTTTAAAAAGTCGCAGAAAACTATAGCCTATCCTTATGGCTTGATGAATGACGATAAATTACCGGTA
ATCAAAAAAGCTGGGTTAAAATACGGTTTTTCATTAGAGGAAAAAGCAGTCACTCCGAACTCCAATGATTATTACATCCC
TAGAATATTAATTAGTGATGATGCTTTTGAGCATTTAATTAAGAGATGGGACGGATTCCATGAAAAAGATTAG

Upstream 100 bases:

>100_bases
TTTTAGATATATTTGAAACTATGGGCATTTTCGCGATTATCATTTTTGTATTTTTTACAATTAGCATATTGATTCAAAAA
TGGCAGAGAGGAAGAGAATC

Downstream 100 bases:

>100_bases
ACTTGAACTCGTATATTTACGTGCTATTATATGTGCAATTATTATTATCACACATTTACTTACACAAATTACTTTAAAAC
ATGAAAATTTGGAGGGAGGA

Product: intercellular adhesion protein B

Products: NA

Alternate protein names: PNAG N-deacetylase; Poly-beta-1,6-GlcNAc N-deacetylase; Biofilm polysaccharide intercellular adhesin deacetylase; Biofilm PIA deacetylase; Intercellular adhesion protein B [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MKYRKLIILVLSILIILPVSTLDGHHIANADDDPPKKLKYKENSALALNYHRVRKANFLNNFLYFFSSSKEIKNYSVSQS
QFESQIKWLKSHDAKFLTLKEFLYYKKKGKFPKRSVWINFDDMDETIYENAYPILKKYKIPATGFIITGHVGEENFHNLD
MISKKELKEMYKTGLWEFETHTHDLHNLSKNNKSKLMKASEATIIKDLNKSEKYLTKNFKKSQKTIAYPYGLMNDDKLPV
IKKAGLKYGFSLEEKAVTPNSNDYYIPRILISDDAFEHLIKRWDGFHEKD

Sequences:

>Translated_290_residues
MKYRKLIILVLSILIILPVSTLDGHHIANADDDPPKKLKYKENSALALNYHRVRKANFLNNFLYFFSSSKEIKNYSVSQS
QFESQIKWLKSHDAKFLTLKEFLYYKKKGKFPKRSVWINFDDMDETIYENAYPILKKYKIPATGFIITGHVGEENFHNLD
MISKKELKEMYKTGLWEFETHTHDLHNLSKNNKSKLMKASEATIIKDLNKSEKYLTKNFKKSQKTIAYPYGLMNDDKLPV
IKKAGLKYGFSLEEKAVTPNSNDYYIPRILISDDAFEHLIKRWDGFHEKD
>Mature_290_residues
MKYRKLIILVLSILIILPVSTLDGHHIANADDDPPKKLKYKENSALALNYHRVRKANFLNNFLYFFSSSKEIKNYSVSQS
QFESQIKWLKSHDAKFLTLKEFLYYKKKGKFPKRSVWINFDDMDETIYENAYPILKKYKIPATGFIITGHVGEENFHNLD
MISKKELKEMYKTGLWEFETHTHDLHNLSKNNKSKLMKASEATIIKDLNKSEKYLTKNFKKSQKTIAYPYGLMNDDKLPV
IKKAGLKYGFSLEEKAVTPNSNDYYIPRILISDDAFEHLIKRWDGFHEKD

Specific function: Catalyzes the N-deacetylation of poly-beta-1,6-N-acetyl- D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. N-deacetylation is crucial for attachment of the polysaccharide to the bacterial cell surface; it leads to the introd

COG id: COG0726

COG function: function code G; Predicted xylanase/chitin deacetylase

Gene ontology:

Cell location: Secreted, cell wall. Note=Attached to the cell surface [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polysaccharide deacetylase family [H]

Homologues:

Organism=Escherichia coli, GI1786322, Length=212, Percent_Identity=28.7735849056604, Blast_Score=95, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011330
- InterPro:   IPR002509 [H]

Pfam domain/function: PF01522 Polysacc_deac_1 [H]

EC number: NA

Molecular weight: Translated: 34082; Mature: 34082

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYRKLIILVLSILIILPVSTLDGHHIANADDDPPKKLKYKENSALALNYHRVRKANFLN
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCEECCCCEEEEEHHHHHHHHHHH
NFLYFFSSSKEIKNYSVSQSQFESQIKWLKSHDAKFLTLKEFLYYKKKGKFPKRSVWINF
HHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCEEEEEE
DDMDETIYENAYPILKKYKIPATGFIITGHVGEENFHNLDMISKKELKEMYKTGLWEFET
CCHHHHHHHCCCHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCEEECC
HTHDLHNLSKNNKSKLMKASEATIIKDLNKSEKYLTKNFKKSQKTIAYPYGLMNDDKLPV
CHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCH
IKKAGLKYGFSLEEKAVTPNSNDYYIPRILISDDAFEHLIKRWDGFHEKD
HHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKYRKLIILVLSILIILPVSTLDGHHIANADDDPPKKLKYKENSALALNYHRVRKANFLN
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCEECCCCEEEEEHHHHHHHHHHH
NFLYFFSSSKEIKNYSVSQSQFESQIKWLKSHDAKFLTLKEFLYYKKKGKFPKRSVWINF
HHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCEEEEEE
DDMDETIYENAYPILKKYKIPATGFIITGHVGEENFHNLDMISKKELKEMYKTGLWEFET
CCHHHHHHHCCCHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCEEECC
HTHDLHNLSKNNKSKLMKASEATIIKDLNKSEKYLTKNFKKSQKTIAYPYGLMNDDKLPV
CHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCH
IKKAGLKYGFSLEEKAVTPNSNDYYIPRILISDDAFEHLIKRWDGFHEKD
HHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA