Click here to switch to the map view.

The map label for this gene is icaC

Identifier: 82752247

GI number: 82752247

Start: 2699714

End: 2700766

Strand: Direct

Name: icaC

Synonym: SAB2544

Alternate gene names: 82752247

Gene position: 2699714-2700766 (Clockwise)

Preceding gene: 82752246

Following gene: 82752265

Centisome position: 98.44

GC content: 26.97

Gene sequence:

>1053_bases
ATGAAAAAGATTAGACTTGAACTCGTATATTTACGTGCTATTATATGTGCAATTATTATTATCACACATTTACTTACACA
AATTACTTTAAAACATGAAAATTTGGAGGGAGGATCCTTAGTATTACAATTTTACATTCGTAATATTGTGATTTTTGGTA
CACCTTGCTTTATTATCTTGTCACAGTTACTGACAACCTTGAATTACCAAAAAGTCACCTATAGATACTTAACTACACGC
GTAAAATATATACTTATTCCTTACATATTAATGGGATTGTTTTACAGTTATAGTGAATCATTATTAACAGATTCAAGTTT
CAATAAACAATTCATTGAAAATGTCCTATTAGGTCAATGGTATGGCTATTTTATCGTTGTTATCATGCAATTCTTTATTT
TGAGTTATATCATTTTTAAAATTAACTATAACCTATTCAATAGTAAAATATTATTATTGTTATCTTTTATTTTACAGCAA
TCTTTTTTATATTACTTTACGAATAACACAGCGTTTCACGATACCGTGCTACACTATTATCCATTAAGTGAAAACACTAT
AATATTCGGATGGATTTTTTATTTCTTTTTAGGTGCATATATGGGTTATAACTACGAACGTGTATTAAATTTCTTAGAAC
GTTATTTAGTTATTATGATTGTATTAGCTGTAGCTACTTATTTTGTGTTTATTGCGTTAGCAAATGGAGACTATTGGAAC
GTTACCAGCTTTTCATATTCATTAACACCATATAATAGTATTATGTTTATTGTTATCTTGGGTATTTGCACGCATTTTAA
AACAATGTTATTTAATACGATTCAAATGATTAGTGCTTTCTCATTCTTTATTTATTTATTACATCCAATCATTCTAGACT
CATTGTTTGCATATACAAATATATTTGAGGATAATACAATGGTCTTTCTAGCGATATCACTACTATTCATTTTAGGGTTA
TGTATAGGTGTCGGTATGATATTGCGTGAATTCTATATCTTTAGGTTTATTATTGGAAAACAACCATATAAATTGAACAT
TAATGCTTATTAA

Upstream 100 bases:

>100_bases
GAAAAAGCAGTCACTCCGAACTCCAATGATTATTACATCCCTAGAATATTAATTAGTGATGATGCTTTTGAGCATTTAAT
TAAGAGATGGGACGGATTCC

Downstream 100 bases:

>100_bases
TTATTAAGCTATGTTAAAAACACGCGGTGGGCGAAATCAGTTTGAATTGACTGACTTCGTTTGACCGCGTGTTTAATATT
GTTATACATATATTCTAAAT

Product: intercellular adhesion protein C

Products: NA

Alternate protein names: PGA export protein; Poly-beta-1,6-GlcNAc export protein; Biofilm polysaccharide intercellular adhesin export protein; Biofilm PIA export protein; Intercellular adhesion protein C [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MKKIRLELVYLRAIICAIIIITHLLTQITLKHENLEGGSLVLQFYIRNIVIFGTPCFIILSQLLTTLNYQKVTYRYLTTR
VKYILIPYILMGLFYSYSESLLTDSSFNKQFIENVLLGQWYGYFIVVIMQFFILSYIIFKINYNLFNSKILLLLSFILQQ
SFLYYFTNNTAFHDTVLHYYPLSENTIIFGWIFYFFLGAYMGYNYERVLNFLERYLVIMIVLAVATYFVFIALANGDYWN
VTSFSYSLTPYNSIMFIVILGICTHFKTMLFNTIQMISAFSFFIYLLHPIILDSLFAYTNIFEDNTMVFLAISLLFILGL
CIGVGMILREFYIFRFIIGKQPYKLNINAY

Sequences:

>Translated_350_residues
MKKIRLELVYLRAIICAIIIITHLLTQITLKHENLEGGSLVLQFYIRNIVIFGTPCFIILSQLLTTLNYQKVTYRYLTTR
VKYILIPYILMGLFYSYSESLLTDSSFNKQFIENVLLGQWYGYFIVVIMQFFILSYIIFKINYNLFNSKILLLLSFILQQ
SFLYYFTNNTAFHDTVLHYYPLSENTIIFGWIFYFFLGAYMGYNYERVLNFLERYLVIMIVLAVATYFVFIALANGDYWN
VTSFSYSLTPYNSIMFIVILGICTHFKTMLFNTIQMISAFSFFIYLLHPIILDSLFAYTNIFEDNTMVFLAISLLFILGL
CIGVGMILREFYIFRFIIGKQPYKLNINAY
>Mature_350_residues
MKKIRLELVYLRAIICAIIIITHLLTQITLKHENLEGGSLVLQFYIRNIVIFGTPCFIILSQLLTTLNYQKVTYRYLTTR
VKYILIPYILMGLFYSYSESLLTDSSFNKQFIENVLLGQWYGYFIVVIMQFFILSYIIFKINYNLFNSKILLLLSFILQQ
SFLYYFTNNTAFHDTVLHYYPLSENTIIFGWIFYFFLGAYMGYNYERVLNFLERYLVIMIVLAVATYFVFIALANGDYWN
VTSFSYSLTPYNSIMFIVILGICTHFKTMLFNTIQMISAFSFFIYLLHPIILDSLFAYTNIFEDNTMVFLAISLLFILGL
CIGVGMILREFYIFRFIIGKQPYKLNINAY

Specific function: Presumably involved in the export of the biofilm adhesin polysaccharide poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA) across the cell membrane [H]

COG id: COG3936

COG function: function code G; Protein involved in polysaccharide intercellular adhesin (PIA) synthesis/biofilm formation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyltransferase 3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002656 [H]

Pfam domain/function: PF01757 Acyl_transf_3 [H]

EC number: NA

Molecular weight: Translated: 41327; Mature: 41327

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS00284 SERPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIRLELVYLRAIICAIIIITHLLTQITLKHENLEGGSLVLQFYIRNIVIFGTPCFIIL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHH
SQLLTTLNYQKVTYRYLTTRVKYILIPYILMGLFYSYSESLLTDSSFNKQFIENVLLGQW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
YGYFIVVIMQFFILSYIIFKINYNLFNSKILLLLSFILQQSFLYYFTNNTAFHDTVLHYY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHEEEE
PLSENTIIFGWIFYFFLGAYMGYNYERVLNFLERYLVIMIVLAVATYFVFIALANGDYWN
ECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VTSFSYSLTPYNSIMFIVILGICTHFKTMLFNTIQMISAFSFFIYLLHPIILDSLFAYTN
EEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFEDNTMVFLAISLLFILGLCIGVGMILREFYIFRFIIGKQPYKLNINAY
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
>Mature Secondary Structure
MKKIRLELVYLRAIICAIIIITHLLTQITLKHENLEGGSLVLQFYIRNIVIFGTPCFIIL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHH
SQLLTTLNYQKVTYRYLTTRVKYILIPYILMGLFYSYSESLLTDSSFNKQFIENVLLGQW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
YGYFIVVIMQFFILSYIIFKINYNLFNSKILLLLSFILQQSFLYYFTNNTAFHDTVLHYY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHEEEE
PLSENTIIFGWIFYFFLGAYMGYNYERVLNFLERYLVIMIVLAVATYFVFIALANGDYWN
ECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VTSFSYSLTPYNSIMFIVILGICTHFKTMLFNTIQMISAFSFFIYLLHPIILDSLFAYTN
EEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFEDNTMVFLAISLLFILGLCIGVGMILREFYIFRFIIGKQPYKLNINAY
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10496925 [H]