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The map label for this gene is icaD

Identifier: 82752245

GI number: 82752245

Start: 2698541

End: 2698858

Strand: Direct

Name: icaD

Synonym: SAB2542

Alternate gene names: 82752245

Gene position: 2698541-2698858 (Clockwise)

Preceding gene: 82752244

Following gene: 82752246

Centisome position: 98.4

GC content: 32.7

Gene sequence:

>318_bases
GTGGTTACGCAACATGGTCAAGCCCAGACAGAGGGAATACCCAACGCTAAAATCATCGCTAAATATGTAAGAGAAACAGC
ACTTATCGCTATATCGTGTGTCTTTTGGATATATTGTTTAGTTGTTCTACTCGTTTATATTGGTACTATATTTGAAATTC
ATGACGAAAGTATCAATACAATACGTGTTGCTTTAAACATTGAAAATACTGAAATTTTAGATATATTTGAAACTATGGGC
ATTTTCGCGATTATCATTTTTGTATTTTTTACAATTAGCATATTGATTCAAAAATGGCAGAGAGGAAGAGAATCGTGA

Upstream 100 bases:

>100_bases
GCTGGACTCATATTTGTAAGTTGGTATCCGACAGTATACTGGATTATTAACGCAGCAGTAGTTCTTGTCGCATTTCCAAA
AGCATTAAAACGTAAGAAAG

Downstream 100 bases:

>100_bases
AGTATAGAAAATTAATAATTTTAGTGCTGAGTATCTTGATCATATTGCCTGTAAGCACACTGGATGGTCATCATATTGCA
AATGCAGATGACGATCCACC

Product: intercellular adhesion protein D

Products: NA

Alternate protein names: PGA synthesis protein IcaD; Poly-beta-1,6-GlcNAc synthesis protein IcaD; Biofilm polysaccharide intercellular adhesin synthesis protein IcaD; Biofilm PIA synthesis protein IcaD; Intercellular adhesion protein D [H]

Number of amino acids: Translated: 105; Mature: 105

Protein sequence:

>105_residues
MVTQHGQAQTEGIPNAKIIAKYVRETALIAISCVFWIYCLVVLLVYIGTIFEIHDESINTIRVALNIENTEILDIFETMG
IFAIIIFVFFTISILIQKWQRGRES

Sequences:

>Translated_105_residues
MVTQHGQAQTEGIPNAKIIAKYVRETALIAISCVFWIYCLVVLLVYIGTIFEIHDESINTIRVALNIENTEILDIFETMG
IFAIIIFVFFTISILIQKWQRGRES
>Mature_105_residues
MVTQHGQAQTEGIPNAKIIAKYVRETALIAISCVFWIYCLVVLLVYIGTIFEIHDESINTIRVALNIENTEILDIFETMG
IFAIIIFVFFTISILIQKWQRGRES

Specific function: Necessary for the synthesis of poly-beta-1,6-N-acetyl-D- glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. Is required for full IcaA N- acetylglucosaminyltransferase activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IcaD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020510
- ProDom:   PD068114 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 12021; Mature: 12021

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTQHGQAQTEGIPNAKIIAKYVRETALIAISCVFWIYCLVVLLVYIGTIFEIHDESINT
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
IRVALNIENTEILDIFETMGIFAIIIFVFFTISILIQKWQRGRES
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVTQHGQAQTEGIPNAKIIAKYVRETALIAISCVFWIYCLVVLLVYIGTIFEIHDESINT
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
IRVALNIENTEILDIFETMGIFAIIIFVFFTISILIQKWQRGRES
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10496925 [H]