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The map label for this gene is flp [H]

Identifier: 82752037

GI number: 82752037

Start: 2456488

End: 2457987

Strand: Direct

Name: flp [H]

Synonym: SAB2323

Alternate gene names: 82752037

Gene position: 2456488-2457987 (Clockwise)

Preceding gene: 82752035

Following gene: 82752045

Centisome position: 89.57

GC content: 31.53

Gene sequence:

>1500_bases
ATGACTACTAAAAAACTGTATTTTCTATCCATTTCTATTATCATTTTAGTCGCCATTTCAATTGCTATATATATAACATT
AAATAGCAATACGAAGACACGGTTAACCAATGATTCGCAACAACAAATAGATACAATTATCGAACATGATTTACAAAAGG
GACATATTCCTGGAGCATCAATTTTAATAGTAAAAAATGGCAAAGTTTTTTTAAATAAAGGTTATGGTTATCAAGATGTT
GATAAAAAAGTCAAAGCTTCTCCCACAACGAAGTATGAAATTGCTTCTAATACGAAACCTTTCACAGGTCTTGCAATTTT
AAAATTAGCTCAAGAAGGTCGATTAAACTTAAATGATGCCGTATCCAAACATGTGCCCCATTTTAAAATGAACTATAATG
GTCAAAATGAAACTATTACGATTAAGCAACTTTTGGCTCAAACAAGTGGTATACCTAGTGATATTACAAGCGAAGACACC
GTAACAAACAAAAATAATCGTTTAAATGATGTAACCCGTGCAATTATGGGTGATGAATTACATCATAAGCCCGGAGAAGA
ATTTGAATACTCAAATATGAACTATGATTTATTAGGTTTAATTATCCAAAACGTTACGAAGCAATCCTATACAAAATATA
TTACAAATTCATGGCTCAAGCCTTTGCATATGACACATACATCATTCAAACAAACTAATAACAAATCAAAAAATGATGCT
ATTGGCTACGAATTACAAGGTTCGACACCTGTCGTCTCTAAACCTGAATTCAACCTTTGGGATACACCATCAGCATATAT
GATGACATCAACTGAAGATTTGGAACATTGGATAAAATTCCAACTTAATCCACCTGATAAATACAAATCATTAGTTCAAC
AATCACATAAAAATTTATCATCAACAATTGGTGAACCTAATGCCAATGCATATGCTTCCGGCTGGTTTACCAATAATGAT
GAACGTTTAGTGTTTCATTCAGGAACGCTCGATAACTTTTCATCATTTATTTTACTAAATCCAAAACAAAATTATGGAAT
TGTTGTGCTTGCAAATCTAAATTCGGAATATGTACCCAAATTGGTTGAGCATCTTAACACACAAATTGTAAATCACAAGC
GATATTCGACAGTTGCGTCTATGCTCAATCAATATAAAAATCAATTTAATATTGTTACCGTTTTGATGACAACACTTATT
TTATTAGCATTTATATTCTCAGCTTATCGTGCTTGGCAAATGCGTCACGGGAAAATCATCTTGCGCAAATCAAAACTTAC
CACATTTTTAAGTTGGCTAACTTTATGTTTATGTATCGCTATAGCACTCATATTATATGCATTACCATATCTCATTCTCG
GTAGCAATAACTGGTCTTTTGTACTGACTTGGTTGCCAATAGAAATTAAATTAACGTTAACTACAACATTTATTGCATTA
TTCAGTATGTTAATTACAATTCTGTTAGTACTACATACAACGACAATTAAGAAATCATAA

Upstream 100 bases:

>100_bases
GTAAATATACCTCTTTAATTAATTTATTCAATGGAACTGGTATAATAAAATAAATCTCATTAGGCACTTAAGTAAATTTA
ACATATAAAAAGGAACGTTT

Downstream 100 bases:

>100_bases
AAAAGACTTGTTCAATCGCACATCAATCCTCATACATATTTATGTATGAGGATTGATGTGCGATTGAACAAGTCTTCATT
ATTAACATGCTATATTCACA

Product: drug resistance-involved membrane protein

Products: NA

Alternate protein names: FmtA-like protein [H]

Number of amino acids: Translated: 499; Mature: 498

Protein sequence:

>499_residues
MTTKKLYFLSISIIILVAISIAIYITLNSNTKTRLTNDSQQQIDTIIEHDLQKGHIPGASILIVKNGKVFLNKGYGYQDV
DKKVKASPTTKYEIASNTKPFTGLAILKLAQEGRLNLNDAVSKHVPHFKMNYNGQNETITIKQLLAQTSGIPSDITSEDT
VTNKNNRLNDVTRAIMGDELHHKPGEEFEYSNMNYDLLGLIIQNVTKQSYTKYITNSWLKPLHMTHTSFKQTNNKSKNDA
IGYELQGSTPVVSKPEFNLWDTPSAYMMTSTEDLEHWIKFQLNPPDKYKSLVQQSHKNLSSTIGEPNANAYASGWFTNND
ERLVFHSGTLDNFSSFILLNPKQNYGIVVLANLNSEYVPKLVEHLNTQIVNHKRYSTVASMLNQYKNQFNIVTVLMTTLI
LLAFIFSAYRAWQMRHGKIILRKSKLTTFLSWLTLCLCIAIALILYALPYLILGSNNWSFVLTWLPIEIKLTLTTTFIAL
FSMLITILLVLHTTTIKKS

Sequences:

>Translated_499_residues
MTTKKLYFLSISIIILVAISIAIYITLNSNTKTRLTNDSQQQIDTIIEHDLQKGHIPGASILIVKNGKVFLNKGYGYQDV
DKKVKASPTTKYEIASNTKPFTGLAILKLAQEGRLNLNDAVSKHVPHFKMNYNGQNETITIKQLLAQTSGIPSDITSEDT
VTNKNNRLNDVTRAIMGDELHHKPGEEFEYSNMNYDLLGLIIQNVTKQSYTKYITNSWLKPLHMTHTSFKQTNNKSKNDA
IGYELQGSTPVVSKPEFNLWDTPSAYMMTSTEDLEHWIKFQLNPPDKYKSLVQQSHKNLSSTIGEPNANAYASGWFTNND
ERLVFHSGTLDNFSSFILLNPKQNYGIVVLANLNSEYVPKLVEHLNTQIVNHKRYSTVASMLNQYKNQFNIVTVLMTTLI
LLAFIFSAYRAWQMRHGKIILRKSKLTTFLSWLTLCLCIAIALILYALPYLILGSNNWSFVLTWLPIEIKLTLTTTFIAL
FSMLITILLVLHTTTIKKS
>Mature_498_residues
TTKKLYFLSISIIILVAISIAIYITLNSNTKTRLTNDSQQQIDTIIEHDLQKGHIPGASILIVKNGKVFLNKGYGYQDVD
KKVKASPTTKYEIASNTKPFTGLAILKLAQEGRLNLNDAVSKHVPHFKMNYNGQNETITIKQLLAQTSGIPSDITSEDTV
TNKNNRLNDVTRAIMGDELHHKPGEEFEYSNMNYDLLGLIIQNVTKQSYTKYITNSWLKPLHMTHTSFKQTNNKSKNDAI
GYELQGSTPVVSKPEFNLWDTPSAYMMTSTEDLEHWIKFQLNPPDKYKSLVQQSHKNLSSTIGEPNANAYASGWFTNNDE
RLVFHSGTLDNFSSFILLNPKQNYGIVVLANLNSEYVPKLVEHLNTQIVNHKRYSTVASMLNQYKNQFNIVTVLMTTLIL
LAFIFSAYRAWQMRHGKIILRKSKLTTFLSWLTLCLCIAIALILYALPYLILGSNNWSFVLTWLPIEIKLTLTTTFIALF
SMLITILLVLHTTTIKKS

Specific function: Its precise function is unknown. Has no penicillin- binding activity and is not involved in methicillin resistance [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87082101, Length=247, Percent_Identity=29.5546558704453, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790593, Length=360, Percent_Identity=23.3333333333333, Blast_Score=81, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115533026, Length=397, Percent_Identity=22.4181360201511, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17550934, Length=182, Percent_Identity=26.9230769230769, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17565630, Length=209, Percent_Identity=25.3588516746411, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 56613; Mature: 56482

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTKKLYFLSISIIILVAISIAIYITLNSNTKTRLTNDSQQQIDTIIEHDLQKGHIPGAS
CCCCEEEHHHHHHHHHHHHHHEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCE
ILIVKNGKVFLNKGYGYQDVDKKVKASPTTKYEIASNTKPFTGLAILKLAQEGRLNLNDA
EEEEECCEEEEECCCCCHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCHHH
VSKHVPHFKMNYNGQNETITIKQLLAQTSGIPSDITSEDTVTNKNNRLNDVTRAIMGDEL
HHHCCCCEEEEECCCCCEEHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHH
HHKPGEEFEYSNMNYDLLGLIIQNVTKQSYTKYITNSWLKPLHMTHTSFKQTNNKSKNDA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCC
IGYELQGSTPVVSKPEFNLWDTPSAYMMTSTEDLEHWIKFQLNPPDKYKSLVQQSHKNLS
CCEEECCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHEEEECCCCHHHHHHHHHHHHHHH
STIGEPNANAYASGWFTNNDERLVFHSGTLDNFSSFILLNPKQNYGIVVLANLNSEYVPK
HHCCCCCCCCEEECEEECCCCEEEEECCCCCCCCCEEEECCCCCCCEEEEECCCCHHHHH
LVEHLNTQIVNHKRYSTVASMLNQYKNQFNIVTVLMTTLILLAFIFSAYRAWQMRHGKII
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LRKSKLTTFLSWLTLCLCIAIALILYALPYLILGSNNWSFVLTWLPIEIKLTLTTTFIAL
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEEEEEEEEHHHHHHHH
FSMLITILLVLHTTTIKKS
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTKKLYFLSISIIILVAISIAIYITLNSNTKTRLTNDSQQQIDTIIEHDLQKGHIPGAS
CCCEEEHHHHHHHHHHHHHHEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCE
ILIVKNGKVFLNKGYGYQDVDKKVKASPTTKYEIASNTKPFTGLAILKLAQEGRLNLNDA
EEEEECCEEEEECCCCCHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCHHH
VSKHVPHFKMNYNGQNETITIKQLLAQTSGIPSDITSEDTVTNKNNRLNDVTRAIMGDEL
HHHCCCCEEEEECCCCCEEHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHH
HHKPGEEFEYSNMNYDLLGLIIQNVTKQSYTKYITNSWLKPLHMTHTSFKQTNNKSKNDA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCC
IGYELQGSTPVVSKPEFNLWDTPSAYMMTSTEDLEHWIKFQLNPPDKYKSLVQQSHKNLS
CCEEECCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHEEEECCCCHHHHHHHHHHHHHHH
STIGEPNANAYASGWFTNNDERLVFHSGTLDNFSSFILLNPKQNYGIVVLANLNSEYVPK
HHCCCCCCCCEEECEEECCCCEEEEECCCCCCCCCEEEECCCCCCCEEEEECCCCHHHHH
LVEHLNTQIVNHKRYSTVASMLNQYKNQFNIVTVLMTTLILLAFIFSAYRAWQMRHGKII
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LRKSKLTTFLSWLTLCLCIAIALILYALPYLILGSNNWSFVLTWLPIEIKLTLTTTFIAL
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEEEEEEEEHHHHHHHH
FSMLITILLVLHTTTIKKS
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA