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The map label for this gene is pucG [H]

Identifier: 82703653

GI number: 82703653

Start: 2906048

End: 2907289

Strand: Direct

Name: pucG [H]

Synonym: Nmul_A2538

Alternate gene names: 82703653

Gene position: 2906048-2907289 (Clockwise)

Preceding gene: 82703652

Following gene: 82703657

Centisome position: 91.26

GC content: 56.28

Gene sequence:

>1242_bases
ATGACAAGACATTTTGGCCCAACTAAAAACATTGGCACCTTCTATCCACCCCAGCGCGTCCTGATGGGTCCGGGACCTTC
CGACACGCATCCCCGGGTTCTCGCGGCAATGGCTCGTCCCACGCTGGGTCATCTCGACCCGGTATTCACGGACATGATGG
AAGAATTGAAAAGCTTGCTGCGGTATGCCTTTCAGACTTCCAATCTCCTGACCTTCCCGGTTTCAGGCCCGGGCTCGGTA
GGCATGGAAATGTGCTTCGTCAATATGGTGAACCCTGGCGACAAGGTAATCGTGTGCCGCAATGGGGTATTTGGGGGACG
CATGATCGAGAACGTTCAGCGTTGCGGAGGCACCGCCGTGGTGGTGGAAGACAAGTGGGGCGCCCCGGTCGATCCGCAAA
AGGTGGAAGATGCCCTGAAGCAGAATCCCGACGCAAAGATTGTCGCTTTCGTTCACGCGGAGACTTCCACCGGGGCTCTG
TCGGATGCCAGAACGCTTTGCGAAATCGCCCATCGCCATAACTGCCTCACTATCGTCGACACGGTCACCTCCCTCGGCGG
CTCTCCGCTAAAGGTGGACGAGTGGAAGATCGATGCCATCTACTCCGGCAGCCAGAAATGCCTGTCATGTCCCCCCGGCC
TGTCGCCCATCAGTTTCTCGGAACGAGTGGTTGATCTCGTCAAAAGCCGCAAAACCAAGGTGCAAAGCTGGTTCATGGAC
CTGAACCTTCTGTTCGGCTACTGGGGAAGCACGCGTACTTACCACCATACCGCTCCTACCAATGCGCTCTATGCCTTGCA
CGAATCACTGCTGATGTTGTATGAGGAAGGATTGGAGCATTCCTGGGCCCGTCATCAGCGTAACCATGAAGCACTCAAGG
CTGGATTTGAAACACTCGGGATGGAGTATCTCGTGGAGGAGAACTCTCGCCTGCCGCAGCTTAATTCGGTCCACGTGCCG
CAGGGAATCGATGAGAAAGAGGTGCGCCGCAGATTGCTCGTTGACTACAGTCTCGAAATCGGCGCGGGCCTCGGGGATTT
TGCGGGCAAGATCTGGCGTTTCGGCCTCATGGGTTACTCAAGCCGGATGGAAAATGTCATGCTGTGCCTGGGTGCTTTGG
AAGCGGTATTATCCGATATGGGTATGAAAATCGAACAGGGCACAGCGGAAGCAGCAGCACATCAGGCCTACGCCGCTCAT
CCGTTGCCGGTGGAAAGTAAAAAGACCGCCAAGGCAGCGTGA

Upstream 100 bases:

>100_bases
TACAGGAAGAATTCGCGGATAGCCAAACCCCTGCTCCCTTGATAAAATCGGATTCTTCCCACGCATAATCCACAGATCAT
CATCAAACTCAGGAACAACC

Downstream 100 bases:

>100_bases
TTGCAGGATAAGTGAAGAGAAGCGCGGGTTCCTCCCGGATGGAGAGGCCCGCGCCAGGTTTTCATCAGTGCTCCTACCCA
ATTTATCCCATTTCCGGATC

Product: Serine--pyruvate transaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MTRHFGPTKNIGTFYPPQRVLMGPGPSDTHPRVLAAMARPTLGHLDPVFTDMMEELKSLLRYAFQTSNLLTFPVSGPGSV
GMEMCFVNMVNPGDKVIVCRNGVFGGRMIENVQRCGGTAVVVEDKWGAPVDPQKVEDALKQNPDAKIVAFVHAETSTGAL
SDARTLCEIAHRHNCLTIVDTVTSLGGSPLKVDEWKIDAIYSGSQKCLSCPPGLSPISFSERVVDLVKSRKTKVQSWFMD
LNLLFGYWGSTRTYHHTAPTNALYALHESLLMLYEEGLEHSWARHQRNHEALKAGFETLGMEYLVEENSRLPQLNSVHVP
QGIDEKEVRRRLLVDYSLEIGAGLGDFAGKIWRFGLMGYSSRMENVMLCLGALEAVLSDMGMKIEQGTAEAAAHQAYAAH
PLPVESKKTAKAA

Sequences:

>Translated_413_residues
MTRHFGPTKNIGTFYPPQRVLMGPGPSDTHPRVLAAMARPTLGHLDPVFTDMMEELKSLLRYAFQTSNLLTFPVSGPGSV
GMEMCFVNMVNPGDKVIVCRNGVFGGRMIENVQRCGGTAVVVEDKWGAPVDPQKVEDALKQNPDAKIVAFVHAETSTGAL
SDARTLCEIAHRHNCLTIVDTVTSLGGSPLKVDEWKIDAIYSGSQKCLSCPPGLSPISFSERVVDLVKSRKTKVQSWFMD
LNLLFGYWGSTRTYHHTAPTNALYALHESLLMLYEEGLEHSWARHQRNHEALKAGFETLGMEYLVEENSRLPQLNSVHVP
QGIDEKEVRRRLLVDYSLEIGAGLGDFAGKIWRFGLMGYSSRMENVMLCLGALEAVLSDMGMKIEQGTAEAAAHQAYAAH
PLPVESKKTAKAA
>Mature_412_residues
TRHFGPTKNIGTFYPPQRVLMGPGPSDTHPRVLAAMARPTLGHLDPVFTDMMEELKSLLRYAFQTSNLLTFPVSGPGSVG
MEMCFVNMVNPGDKVIVCRNGVFGGRMIENVQRCGGTAVVVEDKWGAPVDPQKVEDALKQNPDAKIVAFVHAETSTGALS
DARTLCEIAHRHNCLTIVDTVTSLGGSPLKVDEWKIDAIYSGSQKCLSCPPGLSPISFSERVVDLVKSRKTKVQSWFMDL
NLLFGYWGSTRTYHHTAPTNALYALHESLLMLYEEGLEHSWARHQRNHEALKAGFETLGMEYLVEENSRLPQLNSVHVPQ
GIDEKEVRRRLLVDYSLEIGAGLGDFAGKIWRFGLMGYSSRMENVMLCLGALEAVLSDMGMKIEQGTAEAAAHQAYAAHP
LPVESKKTAKAA

Specific function: Could encode ureidoglycolase or L-alanine:glyoxylate aminotransferase, or perhaps both activities [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=365, Percent_Identity=38.6301369863014, Blast_Score=265, Evalue=7e-71,
Organism=Caenorhabditis elegans, GI17536281, Length=363, Percent_Identity=39.3939393939394, Blast_Score=259, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6321079, Length=365, Percent_Identity=26.8493150684932, Blast_Score=105, Evalue=9e-24,
Organism=Drosophila melanogaster, GI17530823, Length=379, Percent_Identity=38.5224274406332, Blast_Score=266, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 45459; Mature: 45328

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRHFGPTKNIGTFYPPQRVLMGPGPSDTHPRVLAAMARPTLGHLDPVFTDMMEELKSLL
CCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
RYAFQTSNLLTFPVSGPGSVGMEMCFVNMVNPGDKVIVCRNGVFGGRMIENVQRCGGTAV
HHHHHCCCEEEEECCCCCCCCHHHHEEEECCCCCEEEEECCCCCCHHHHHHHHHCCCEEE
VVEDKWGAPVDPQKVEDALKQNPDAKIVAFVHAETSTGALSDARTLCEIAHRHNCLTIVD
EEECCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHH
TVTSLGGSPLKVDEWKIDAIYSGSQKCLSCPPGLSPISFSERVVDLVKSRKTKVQSWFMD
HHHHCCCCCEEECCEEEEEEECCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LNLLFGYWGSTRTYHHTAPTNALYALHESLLMLYEEGLEHSWARHQRNHEALKAGFETLG
HHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MEYLVEENSRLPQLNSVHVPQGIDEKEVRRRLLVDYSLEIGAGLGDFAGKIWRFGLMGYS
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHH
SRMENVMLCLGALEAVLSDMGMKIEQGTAEAAAHQAYAAHPLPVESKKTAKAA
HHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TRHFGPTKNIGTFYPPQRVLMGPGPSDTHPRVLAAMARPTLGHLDPVFTDMMEELKSLL
CCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
RYAFQTSNLLTFPVSGPGSVGMEMCFVNMVNPGDKVIVCRNGVFGGRMIENVQRCGGTAV
HHHHHCCCEEEEECCCCCCCCHHHHEEEECCCCCEEEEECCCCCCHHHHHHHHHCCCEEE
VVEDKWGAPVDPQKVEDALKQNPDAKIVAFVHAETSTGALSDARTLCEIAHRHNCLTIVD
EEECCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHH
TVTSLGGSPLKVDEWKIDAIYSGSQKCLSCPPGLSPISFSERVVDLVKSRKTKVQSWFMD
HHHHCCCCCEEECCEEEEEEECCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LNLLFGYWGSTRTYHHTAPTNALYALHESLLMLYEEGLEHSWARHQRNHEALKAGFETLG
HHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MEYLVEENSRLPQLNSVHVPQGIDEKEVRRRLLVDYSLEIGAGLGDFAGKIWRFGLMGYS
HHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHH
SRMENVMLCLGALEAVLSDMGMKIEQGTAEAAAHQAYAAHPLPVESKKTAKAA
HHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11344136 [H]