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The map label for this gene is hupB [H]

Identifier: 82703454

GI number: 82703454

Start: 2662757

End: 2663029

Strand: Reverse

Name: hupB [H]

Synonym: Nmul_A2337

Alternate gene names: 82703454

Gene position: 2663029-2662757 (Counterclockwise)

Preceding gene: 82703455

Following gene: 82703453

Centisome position: 83.63

GC content: 53.85

Gene sequence:

>273_bases
GTGAATAAAGCTGAACTCATCGATGCCATCGCGAAATCATCGGACATTTCCAAAGCTTCGGCGGGAAATGCGCTGGACGG
TGCGCTGGAAGCGATCAAAGCCGCTCTCAAGAAAGGGCAAAGTGTAACACTGGTGGGATTTGGAACGTTCAAGGTAGGCA
CACGTGCCGCCCGCACCGGCCGCAACCCCCGTACAGGCGCTGCTATCACCATCGAATCTACCAAGGTTCCTAAATTCATT
GCTGGCAAGGCGCTCAAGGATGCAGTAAACTAG

Upstream 100 bases:

>100_bases
AGTGGAAATATTTTGACAATGGCTTGACCAGGCACAAGCCGCTTGATATAAAACGTTTGCAGGGTTTTTACTCTCTTAAC
AATAATGAAAGGGGAATCAC

Downstream 100 bases:

>100_bases
CGGCTTATCGGCGGGGGTGCTTAGCTCAGTTGGTAGAGCGTCGCCCTTACAAGGCGAATGTCGGCGGTTCGACCCCGTCA
GCACCCACCAGTTAGATTTA

Product: histone-like DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 90; Mature: 90

Protein sequence:

>90_residues
MNKAELIDAIAKSSDISKASAGNALDGALEAIKAALKKGQSVTLVGFGTFKVGTRAARTGRNPRTGAAITIESTKVPKFI
AGKALKDAVN

Sequences:

>Translated_90_residues
MNKAELIDAIAKSSDISKASAGNALDGALEAIKAALKKGQSVTLVGFGTFKVGTRAARTGRNPRTGAAITIESTKVPKFI
AGKALKDAVN
>Mature_90_residues
MNKAELIDAIAKSSDISKASAGNALDGALEAIKAALKKGQSVTLVGFGTFKVGTRAARTGRNPRTGAAITIESTKVPKFI
AGKALKDAVN

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=64.4444444444444, Blast_Score=113, Evalue=3e-27,
Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=58.4269662921348, Blast_Score=104, Evalue=1e-24,
Organism=Escherichia coli, GI1787141, Length=91, Percent_Identity=39.5604395604396, Blast_Score=76, Evalue=5e-16,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9171; Mature: 9171

Theoretical pI: Translated: 11.02; Mature: 11.02

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKAELIDAIAKSSDISKASAGNALDGALEAIKAALKKGQSVTLVGFGTFKVGTRAARTG
CCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHCC
RNPRTGAAITIESTKVPKFIAGKALKDAVN
CCCCCCEEEEEECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNKAELIDAIAKSSDISKASAGNALDGALEAIKAALKKGQSVTLVGFGTFKVGTRAARTG
CCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHCC
RNPRTGAAITIESTKVPKFIAGKALKDAVN
CCCCCCEEEEEECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7867950; 10984043; 6793399 [H]