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The map label for this gene is uppP

Identifier: 82703404

GI number: 82703404

Start: 2601912

End: 2602733

Strand: Direct

Name: uppP

Synonym: Nmul_A2286

Alternate gene names: 82703404

Gene position: 2601912-2602733 (Clockwise)

Preceding gene: 82703403

Following gene: 82703406

Centisome position: 81.71

GC content: 54.38

Gene sequence:

>822_bases
ATGGACTGGTTTCTTCTCCTCAAGGGGCTCATCCTTGGCATAGTCGAAGGTCTGACGGAATTTCTCCCGATTTCGTCCAC
GGGCCACCTGATTCTGGTCAGCGACCTGCTCAACTTCAATGACGAAAAGGGCAAGGTATTTACCATCGTCATTCAGCTTG
GCGCGATTCTGGCGGTATGCTGGGAATATCGCGTCAAGCTGCGCCATGTAGTGACGGACATCGGATCCCGCCAGGACGCA
AACCGCTTTGTGTTGAATCTCTTGATCGCGTTTCTGCCCGCCGCAATTCTGGGTTTGCTGTTCATCAAAACCATCAAGCA
ATACCTGTTTCATCCGGTACCGGTCGCGCTGGCATTCATAGTCGGCGGCCTTCTAATTCTTTGGGCCGAGCGCCGGCCAC
ATGTGGTGGACGTGGAACGGGTCGAAGACATGGACTGGAAGCATGCCTTGAAGGTGGGATTGGCTCAGTGCCTGGCGCTC
ATACCCGGCACTTCGCGCTCGGGCGCCACCATCATTGGCGGCCTCTTCTTCGGCCTGTCGCGCAAAGCCGCTACTGAATT
TTCATTTTTCCTCGCGATTCCGGTTATGTTCGCGGCGACTTTTTATGATCTTTACAAGAATCGCGATATCCTTCATCTGG
ATGATGCGAGCGTGTTCGCGATCGGGTTCGTGGCATCCTTTATCAGCGCTCTCCTGGCGGTACGAGGTTTACTCCGCTTT
GTCAGCCAGCATGATTTCTCCGTTTTTGCCTGGTATCGCATCGGGTTCGGGATTATCGTCCTGATTACGGCCTACTCCGG
GATGGTTCAGTGGTCGGGGTAA

Upstream 100 bases:

>100_bases
TACTGGATATCCATTGCCTGTATTCCTTGGTAACACCATGGTTCATCCCCGTTCGTTCCCGGTTCCCCGCGGTCTCCCGG
CTTCTGCCGGATAATCTGGA

Downstream 100 bases:

>100_bases
GAAGCATTCCTTTCCAATGAGTTTTGCTCATGCACTGACGCTCTCCATTATTTTCCAGGTTATTGTCACCGCGATAAGCA
CGTTCTGAACTTCTCTAGGG

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MDWFLLLKGLILGIVEGLTEFLPISSTGHLILVSDLLNFNDEKGKVFTIVIQLGAILAVCWEYRVKLRHVVTDIGSRQDA
NRFVLNLLIAFLPAAILGLLFIKTIKQYLFHPVPVALAFIVGGLLILWAERRPHVVDVERVEDMDWKHALKVGLAQCLAL
IPGTSRSGATIIGGLFFGLSRKAATEFSFFLAIPVMFAATFYDLYKNRDILHLDDASVFAIGFVASFISALLAVRGLLRF
VSQHDFSVFAWYRIGFGIIVLITAYSGMVQWSG

Sequences:

>Translated_273_residues
MDWFLLLKGLILGIVEGLTEFLPISSTGHLILVSDLLNFNDEKGKVFTIVIQLGAILAVCWEYRVKLRHVVTDIGSRQDA
NRFVLNLLIAFLPAAILGLLFIKTIKQYLFHPVPVALAFIVGGLLILWAERRPHVVDVERVEDMDWKHALKVGLAQCLAL
IPGTSRSGATIIGGLFFGLSRKAATEFSFFLAIPVMFAATFYDLYKNRDILHLDDASVFAIGFVASFISALLAVRGLLRF
VSQHDFSVFAWYRIGFGIIVLITAYSGMVQWSG
>Mature_273_residues
MDWFLLLKGLILGIVEGLTEFLPISSTGHLILVSDLLNFNDEKGKVFTIVIQLGAILAVCWEYRVKLRHVVTDIGSRQDA
NRFVLNLLIAFLPAAILGLLFIKTIKQYLFHPVPVALAFIVGGLLILWAERRPHVVDVERVEDMDWKHALKVGLAQCLAL
IPGTSRSGATIIGGLFFGLSRKAATEFSFFLAIPVMFAATFYDLYKNRDILHLDDASVFAIGFVASFISALLAVRGLLRF
VSQHDFSVFAWYRIGFGIIVLITAYSGMVQWSG

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=260, Percent_Identity=45.7692307692308, Blast_Score=204, Evalue=6e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_NITMU (Q2Y6P3)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_412970.1
- STRING:   Q2Y6P3
- GeneID:   3785102
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A2286
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   LVQCLAM
- PhylomeDB:   Q2Y6P3
- ProtClustDB:   PRK00281
- BioCyc:   NMUL323848:NMUL_A2286-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 30347; Mature: 30347

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x14e7afd4)-; HASH(0x15246100)-; HASH(0x141f7474)-; HASH(0x151cede8)-; HASH(0x14983b7c)-; HASH(0x14ef43c0)-; HASH(0x14e9b964)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWFLLLKGLILGIVEGLTEFLPISSTGHLILVSDLLNFNDEKGKVFTIVIQLGAILAVC
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHCCCCCCCHHHHHHHHHHHHHHHH
WEYRVKLRHVVTDIGSRQDANRFVLNLLIAFLPAAILGLLFIKTIKQYLFHPVPVALAFI
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VGGLLILWAERRPHVVDVERVEDMDWKHALKVGLAQCLALIPGTSRSGATIIGGLFFGLS
HHHHHHHHHCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
RKAATEFSFFLAIPVMFAATFYDLYKNRDILHLDDASVFAIGFVASFISALLAVRGLLRF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
VSQHDFSVFAWYRIGFGIIVLITAYSGMVQWSG
HHHCCCHHHHHHHHHHHHHHHHHHHCCCEEECH
>Mature Secondary Structure
MDWFLLLKGLILGIVEGLTEFLPISSTGHLILVSDLLNFNDEKGKVFTIVIQLGAILAVC
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHCCCCCCCHHHHHHHHHHHHHHHH
WEYRVKLRHVVTDIGSRQDANRFVLNLLIAFLPAAILGLLFIKTIKQYLFHPVPVALAFI
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VGGLLILWAERRPHVVDVERVEDMDWKHALKVGLAQCLALIPGTSRSGATIIGGLFFGLS
HHHHHHHHHCCCCCEEEHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
RKAATEFSFFLAIPVMFAATFYDLYKNRDILHLDDASVFAIGFVASFISALLAVRGLLRF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
VSQHDFSVFAWYRIGFGIIVLITAYSGMVQWSG
HHHCCCHHHHHHHHHHHHHHHHHHHCCCEEECH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA