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The map label for this gene is hypB [H]

Identifier: 82702790

GI number: 82702790

Start: 1903661

End: 1904467

Strand: Direct

Name: hypB [H]

Synonym: Nmul_A1666

Alternate gene names: 82702790

Gene position: 1903661-1904467 (Clockwise)

Preceding gene: 82702789

Following gene: 82702791

Centisome position: 59.78

GC content: 55.27

Gene sequence:

>807_bases
ATGTGCAACACGTGTGGTTGCAACATCACACCCGGTAACCGGGAATTTGCTTATAAGCCGGTAAACGGCATGACCCCGGT
TTCGGTCCTGAAGAACCTGCTGGCCAAAAATAATGACCAAGCGGAACACAACCGCCGGCATTTCGACAGGCATCGGCTGC
TGACAGTAAACCTGATGTCATCCCCTGGCGCCGGCAAGACGGCCTTGCTGGAAGCGTCCATTGATGCTTTGCGTGACAAG
TACCGTATCGGTGTGATCGAGGGTGATCTGGAAACCGAAAACGATGCGGTGCGCATCCGCGCCAGAGGAGCGCCGGCATA
CCAGATCACTACAGGATCGGCGTGCCATCTCGATGCCCACATGGTGCACGACGCATTGCATGAATTTCCGCTGGAGGAAC
TGGATATCCTGTTTATCGAGAACGTAGGCAACCTCGTGTGCCCGGCAAGCTTTGATCTGGGCCAGCATAGGAATGTCACT
CTGCTCTCTGTCACGGAAGGCGATGATAAGCCCGCAAAATACCCCGTGATGTTCCGCGCCGCGGATGCGGTAATTCTCAC
CAAAAGCGACCTATTGCCAGTGCTGGATGACTTTGATCCGGCTCGAGCAGAACTCAGTCTTCGCAACCTGGGTAGCCGAG
CACCGGTAATCAGGCTTTCCGCCCGGAAGAATCTGAACCTCGGTGATTGGCTTGATTGGCTTATCGGCGAACTGGTGCAG
AAACGGGGGAAATTAGCTGCGGACGTTCTGGCACAACCTGTGGCAGACCCGCAATCGATATTGTCCAATACGGGAATGGG
CGGATGA

Upstream 100 bases:

>100_bases
CCGCATGTGTGGGAGTTGTCTGATCAGAGTTGTGAGTGGCGAGGAATTGACGCTCATGAGTGTTGAATTGATCACCACTT
GAAGTCTCGGGAGGTCTGGA

Downstream 100 bases:

>100_bases
CACTTACCGCTCAGGAGTGGCTAAAAAAAATCCATGAGCTGCCACTCGATCGCCCTGTACGTATCATGAACGTATGCGGA
GGCCATGAGCGTTCGATTAC

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MCNTCGCNITPGNREFAYKPVNGMTPVSVLKNLLAKNNDQAEHNRRHFDRHRLLTVNLMSSPGAGKTALLEASIDALRDK
YRIGVIEGDLETENDAVRIRARGAPAYQITTGSACHLDAHMVHDALHEFPLEELDILFIENVGNLVCPASFDLGQHRNVT
LLSVTEGDDKPAKYPVMFRAADAVILTKSDLLPVLDDFDPARAELSLRNLGSRAPVIRLSARKNLNLGDWLDWLIGELVQ
KRGKLAADVLAQPVADPQSILSNTGMGG

Sequences:

>Translated_268_residues
MCNTCGCNITPGNREFAYKPVNGMTPVSVLKNLLAKNNDQAEHNRRHFDRHRLLTVNLMSSPGAGKTALLEASIDALRDK
YRIGVIEGDLETENDAVRIRARGAPAYQITTGSACHLDAHMVHDALHEFPLEELDILFIENVGNLVCPASFDLGQHRNVT
LLSVTEGDDKPAKYPVMFRAADAVILTKSDLLPVLDDFDPARAELSLRNLGSRAPVIRLSARKNLNLGDWLDWLIGELVQ
KRGKLAADVLAQPVADPQSILSNTGMGG
>Mature_268_residues
MCNTCGCNITPGNREFAYKPVNGMTPVSVLKNLLAKNNDQAEHNRRHFDRHRLLTVNLMSSPGAGKTALLEASIDALRDK
YRIGVIEGDLETENDAVRIRARGAPAYQITTGSACHLDAHMVHDALHEFPLEELDILFIENVGNLVCPASFDLGQHRNVT
LLSVTEGDDKPAKYPVMFRAADAVILTKSDLLPVLDDFDPARAELSLRNLGSRAPVIRLSARKNLNLGDWLDWLIGELVQ
KRGKLAADVLAQPVADPQSILSNTGMGG

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=203, Percent_Identity=51.7241379310345, Blast_Score=203, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 29310; Mature: 29310

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCNTCGCNITPGNREFAYKPVNGMTPVSVLKNLLAKNNDQAEHNRRHFDRHRLLTVNLMS
CCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHEEEEEEEEC
SPGAGKTALLEASIDALRDKYRIGVIEGDLETENDAVRIRARGAPAYQITTGSACHLDAH
CCCCCCEEEHHHHHHHHHHHEEEEEEECCCCCCCCEEEEEECCCCEEEEECCCEEEHHHH
MVHDALHEFPLEELDILFIENVGNLVCPASFDLGQHRNVTLLSVTEGDDKPAKYPVMFRA
HHHHHHHHCCHHHHCEEEEECCCCEECCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEE
ADAVILTKSDLLPVLDDFDPARAELSLRNLGSRAPVIRLSARKNLNLGDWLDWLIGELVQ
CCEEEEECCCCCHHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHH
KRGKLAADVLAQPVADPQSILSNTGMGG
HHCCHHHHHHHCCCCCHHHHHHCCCCCC
>Mature Secondary Structure
MCNTCGCNITPGNREFAYKPVNGMTPVSVLKNLLAKNNDQAEHNRRHFDRHRLLTVNLMS
CCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHEEEEEEEEC
SPGAGKTALLEASIDALRDKYRIGVIEGDLETENDAVRIRARGAPAYQITTGSACHLDAH
CCCCCCEEEHHHHHHHHHHHEEEEEEECCCCCCCCEEEEEECCCCEEEEECCCEEEHHHH
MVHDALHEFPLEELDILFIENVGNLVCPASFDLGQHRNVTLLSVTEGDDKPAKYPVMFRA
HHHHHHHHCCHHHHCEEEEECCCCEECCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEE
ADAVILTKSDLLPVLDDFDPARAELSLRNLGSRAPVIRLSARKNLNLGDWLDWLIGELVQ
CCEEEEECCCCCHHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHH
KRGKLAADVLAQPVADPQSILSNTGMGG
HHCCHHHHHHHCCCCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]