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The map label for this gene is hypA

Identifier: 82702789

GI number: 82702789

Start: 1903295

End: 1903642

Strand: Direct

Name: hypA

Synonym: Nmul_A1665

Alternate gene names: 82702789

Gene position: 1903295-1903642 (Clockwise)

Preceding gene: 82702788

Following gene: 82702790

Centisome position: 59.77

GC content: 51.44

Gene sequence:

>348_bases
ATGCATGAATTCTCTATCTGCCAAGCTTTGATCACACAGGTCGAGCAGATTGCGATCAGCCACGGAGCGTTGAAGGTGCA
ATCGGTAAAGCTCCGGATCGGTTCCCTCTCTGGCGTGGAACTGCCGCTGCTTGAGCATGCGTATCCTTTTGCCAGCGCGG
GTACCCTGGTAGAGGGTTCTACGCTTGAAATAGAGCGTGCTCCACTCAAAGTAAATTGCGAAGCATGCGGCCTCGAATCA
GAGGTTAAGGCAAATTTGCTCACATGCCGCATGTGTGGGAGTTGTCTGATCAGAGTTGTGAGTGGCGAGGAATTGACGCT
CATGAGTGTTGAATTGATCACCACTTGA

Upstream 100 bases:

>100_bases
GTCATGGTGCACGTGGGATACGCCATCCAGAAAATAAACGAAAGCGAGGCGCGCTCAGCCTGGGAGCTTCACGACGAGTT
GCTTGCTGCCGGGGCGGACG

Downstream 100 bases:

>100_bases
AGTCTCGGGAGGTCTGGAATGTGCAACACGTGTGGTTGCAACATCACACCCGGTAACCGGGAATTTGCTTATAAGCCGGT
AAACGGCATGACCCCGGTTT

Product: hydrogenase expression/synthesis, HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 115; Mature: 115

Protein sequence:

>115_residues
MHEFSICQALITQVEQIAISHGALKVQSVKLRIGSLSGVELPLLEHAYPFASAGTLVEGSTLEIERAPLKVNCEACGLES
EVKANLLTCRMCGSCLIRVVSGEELTLMSVELITT

Sequences:

>Translated_115_residues
MHEFSICQALITQVEQIAISHGALKVQSVKLRIGSLSGVELPLLEHAYPFASAGTLVEGSTLEIERAPLKVNCEACGLES
EVKANLLTCRMCGSCLIRVVSGEELTLMSVELITT
>Mature_115_residues
MHEFSICQALITQVEQIAISHGALKVQSVKLRIGSLSGVELPLLEHAYPFASAGTLVEGSTLEIERAPLKVNCEACGLES
EVKANLLTCRMCGSCLIRVVSGEELTLMSVELITT

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family

Homologues:

Organism=Escherichia coli, GI1789365, Length=112, Percent_Identity=30.3571428571429, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1789081, Length=117, Percent_Identity=30.7692307692308, Blast_Score=59, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPA_NITMU (Q2Y8F8)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_412355.1
- STRING:   Q2Y8F8
- GeneID:   3785652
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A1665
- eggNOG:   COG0375
- HOGENOM:   HBG688671
- OMA:   CRAPIAR
- PhylomeDB:   Q2Y8F8
- BioCyc:   NMUL323848:NMUL_A1665-MONOMER
- HAMAP:   MF_00213
- InterPro:   IPR000688

Pfam domain/function: PF01155 HypA

EC number: NA

Molecular weight: Translated: 12330; Mature: 12330

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEFSICQALITQVEQIAISHGALKVQSVKLRIGSLSGVELPLLEHAYPFASAGTLVEGS
CCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCHHHCCCCCCCCCCEECCC
TLEIERAPLKVNCEACGLESEVKANLLTCRMCGSCLIRVVSGEELTLMSVELITT
EEEEECCCEEEEHHCCCCCCHHHHHHHHHHHHHHHHEEEECCCEEEEEEEEEEEC
>Mature Secondary Structure
MHEFSICQALITQVEQIAISHGALKVQSVKLRIGSLSGVELPLLEHAYPFASAGTLVEGS
CCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCHHHCCCCCCCCCCEECCC
TLEIERAPLKVNCEACGLESEVKANLLTCRMCGSCLIRVVSGEELTLMSVELITT
EEEEECCCEEEEHHCCCCCCHHHHHHHHHHHHHHHHEEEECCCEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA