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The map label for this gene is xseA [H]

Identifier: 82702159

GI number: 82702159

Start: 1191375

End: 1192718

Strand: Direct

Name: xseA [H]

Synonym: Nmul_A1030

Alternate gene names: 82702159

Gene position: 1191375-1192718 (Clockwise)

Preceding gene: 82702154

Following gene: 82702160

Centisome position: 37.41

GC content: 57.22

Gene sequence:

>1344_bases
ATGAATCACGTTCTGGAAATGGGTTTCGAGCGGGCGGTCATGAGCGTAAGCGAATTGAACCGCAATGCCAAGGAGTTGCT
GGAGCAGGCTTTTCCATTATCCTGGGTGGCTGGCGAGATCTCCAATATCAAGTGCTATGGCTCCGGCCACTGGTATTTTT
CCCTGAAGGATGAGATTGCTCAGGTGCGCTGTGTCATGTTCCGGGAAAAAAACCAGTATCTTGATTGGCAGCCTCGGGAT
GGCATGCGGGTGGAAGTGCGCGCCCTGGTAACGCTATATCATGCGCGCGGCGATTTCCAACTGAACATCGAGACTATCCG
CCACGCCGGACTCGGTTCGCTGTTTGAAGCTTTCGAGCAACTCAAGGCGAGGCTTGGAAAAGAGGGGTTGTTCGATTCTG
AGCGCAAGAAACCATTGCCAGAGTTTCCAAAGCAGATCGGGATCATCACTTCTCCTGCCGCCGCGGCGCTGCATGATGTG
CTGTCCACCTTGCAGCGGCGTATGCCTTCCGTGCCCATAATCGTTTATCCAACGATTGTTCAGGGCGCTGGCGCTTCAGT
AAGGATCGCGGGCGCCATTCAAACCGCTGCAAGCCGGGCTGAGTGCGATGTACTGATACTGTGCCGCGGGGGTGGCTCTC
TGGAAGATCTGTGGGCTTTCAACGAGGAGGTTGTGGCACGCGCAATCGCGGCTTGTTCCATTCCCATTGTCAGTGGAGTG
GGTCACGAAACCGATTTTACCATTGCGGATTTTGTTGCGGATGTCCGCGCGCCCACGCCGACTGGCGCATCCCAGCTCGT
GTGCCCGGATCGCGCAGAAGTGGCGAGATGCGGAGAAATTCTTCGTGGACGCATGTACCGCGCGATGCAACGGCGCATCG
AAAGCCGGATGCAGCATACGGATATGCTGGGGTGCCGTCTGGTACATCCGGGAAAGCGCATCGAAGCACAACTGGCGCAG
CTTGCGCGTTTGCGCGAACGCCTGGAAAGCGCATGGCTACGTCACGCGAAAGAGAGGCACTGGCGCTTGCGCGAGCTCCA
GCAGCGCATGAAGATTGCCCGGCCCGACATCCCACGGCTGGAAGGGCGCCAGCAGCAACTCGGTCTACGCCTTCAGCGGG
CGATCGCATCCCGGATTGAAACTCTCGGCATGCACTTGCAGCGCAGGGAAGCAAATCTTTCCCATCTGAATCCGGATTCC
GTTCTGGCGCGAGGCTACAGTATTGCTTATACCTCCGATGGCACGGTATTGAGAAGAAATGATCAGGTCGATGTTGGCGA
TGTCATCCGCGTGACGTTTGCGAAAGGATGGAGCAAGGCGTCCGTGATGGAGAAGGGCGAGTAG

Upstream 100 bases:

>100_bases
TTTTAAAACATGGGGTTATGTCATATCCGGATTTCATGCGGGTTGGCGCCGCATAATATGCTATTTTCGTGACAAGTGTG
GATTATTGTAAAATGTCAAG

Downstream 100 bases:

>100_bases
CGGGAATGCGCCTGCAGGATCGCACTCCATGACCTTCCGCCGAGTCTGGACATTCAGCCAAGGGTGGTGCAGACTTGACC
GTTGGCGGGATTGGATTGTG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MNHVLEMGFERAVMSVSELNRNAKELLEQAFPLSWVAGEISNIKCYGSGHWYFSLKDEIAQVRCVMFREKNQYLDWQPRD
GMRVEVRALVTLYHARGDFQLNIETIRHAGLGSLFEAFEQLKARLGKEGLFDSERKKPLPEFPKQIGIITSPAAAALHDV
LSTLQRRMPSVPIIVYPTIVQGAGASVRIAGAIQTAASRAECDVLILCRGGGSLEDLWAFNEEVVARAIAACSIPIVSGV
GHETDFTIADFVADVRAPTPTGASQLVCPDRAEVARCGEILRGRMYRAMQRRIESRMQHTDMLGCRLVHPGKRIEAQLAQ
LARLRERLESAWLRHAKERHWRLRELQQRMKIARPDIPRLEGRQQQLGLRLQRAIASRIETLGMHLQRREANLSHLNPDS
VLARGYSIAYTSDGTVLRRNDQVDVGDVIRVTFAKGWSKASVMEKGE

Sequences:

>Translated_447_residues
MNHVLEMGFERAVMSVSELNRNAKELLEQAFPLSWVAGEISNIKCYGSGHWYFSLKDEIAQVRCVMFREKNQYLDWQPRD
GMRVEVRALVTLYHARGDFQLNIETIRHAGLGSLFEAFEQLKARLGKEGLFDSERKKPLPEFPKQIGIITSPAAAALHDV
LSTLQRRMPSVPIIVYPTIVQGAGASVRIAGAIQTAASRAECDVLILCRGGGSLEDLWAFNEEVVARAIAACSIPIVSGV
GHETDFTIADFVADVRAPTPTGASQLVCPDRAEVARCGEILRGRMYRAMQRRIESRMQHTDMLGCRLVHPGKRIEAQLAQ
LARLRERLESAWLRHAKERHWRLRELQQRMKIARPDIPRLEGRQQQLGLRLQRAIASRIETLGMHLQRREANLSHLNPDS
VLARGYSIAYTSDGTVLRRNDQVDVGDVIRVTFAKGWSKASVMEKGE
>Mature_447_residues
MNHVLEMGFERAVMSVSELNRNAKELLEQAFPLSWVAGEISNIKCYGSGHWYFSLKDEIAQVRCVMFREKNQYLDWQPRD
GMRVEVRALVTLYHARGDFQLNIETIRHAGLGSLFEAFEQLKARLGKEGLFDSERKKPLPEFPKQIGIITSPAAAALHDV
LSTLQRRMPSVPIIVYPTIVQGAGASVRIAGAIQTAASRAECDVLILCRGGGSLEDLWAFNEEVVARAIAACSIPIVSGV
GHETDFTIADFVADVRAPTPTGASQLVCPDRAEVARCGEILRGRMYRAMQRRIESRMQHTDMLGCRLVHPGKRIEAQLAQ
LARLRERLESAWLRHAKERHWRLRELQQRMKIARPDIPRLEGRQQQLGLRLQRAIASRIETLGMHLQRREANLSHLNPDS
VLARGYSIAYTSDGTVLRRNDQVDVGDVIRVTFAKGWSKASVMEKGE

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=435, Percent_Identity=43.6781609195402, Blast_Score=356, Evalue=2e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 50307; Mature: 50307

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHVLEMGFERAVMSVSELNRNAKELLEQAFPLSWVAGEISNIKCYGSGHWYFSLKDEIA
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHECCCCCCEEEEECCEEEEEEHHHHH
QVRCVMFREKNQYLDWQPRDGMRVEVRALVTLYHARGDFQLNIETIRHAGLGSLFEAFEQ
HHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCEEEEHHHHHHCCHHHHHHHHHH
LKARLGKEGLFDSERKKPLPEFPKQIGIITSPAAAALHDVLSTLQRRMPSVPIIVYPTIV
HHHHHCCCCCCCCHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCC
QGAGASVRIAGAIQTAASRAECDVLILCRGGGSLEDLWAFNEEVVARAIAACSIPIVSGV
CCCCCCEEEEHHHHHHHCCCCCCEEEEECCCCCHHHHHHCCHHHHHHHHHHHCCHHHCCC
GHETDFTIADFVADVRAPTPTGASQLVCPDRAEVARCGEILRGRMYRAMQRRIESRMQHT
CCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DMLGCRLVHPGKRIEAQLAQLARLRERLESAWLRHAKERHWRLRELQQRMKIARPDIPRL
HHHCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EGRQQQLGLRLQRAIASRIETLGMHLQRREANLSHLNPDSVLARGYSIAYTSDGTVLRRN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCEEEEEECCCEEEECC
DQVDVGDVIRVTFAKGWSKASVMEKGE
CCCCCCHHHEEHHHCCCCHHCCCCCCC
>Mature Secondary Structure
MNHVLEMGFERAVMSVSELNRNAKELLEQAFPLSWVAGEISNIKCYGSGHWYFSLKDEIA
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHECCCCCCEEEEECCEEEEEEHHHHH
QVRCVMFREKNQYLDWQPRDGMRVEVRALVTLYHARGDFQLNIETIRHAGLGSLFEAFEQ
HHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCEEEEHHHHHHCCHHHHHHHHHH
LKARLGKEGLFDSERKKPLPEFPKQIGIITSPAAAALHDVLSTLQRRMPSVPIIVYPTIV
HHHHHCCCCCCCCHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCC
QGAGASVRIAGAIQTAASRAECDVLILCRGGGSLEDLWAFNEEVVARAIAACSIPIVSGV
CCCCCCEEEEHHHHHHHCCCCCCEEEEECCCCCHHHHHHCCHHHHHHHHHHHCCHHHCCC
GHETDFTIADFVADVRAPTPTGASQLVCPDRAEVARCGEILRGRMYRAMQRRIESRMQHT
CCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DMLGCRLVHPGKRIEAQLAQLARLRERLESAWLRHAKERHWRLRELQQRMKIARPDIPRL
HHHCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EGRQQQLGLRLQRAIASRIETLGMHLQRREANLSHLNPDSVLARGYSIAYTSDGTVLRRN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCEEEEEECCCEEEECC
DQVDVGDVIRVTFAKGWSKASVMEKGE
CCCCCCHHHEEHHHCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]