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The map label for this gene is nuoN

Identifier: 82702154

GI number: 82702154

Start: 1187035

End: 1188558

Strand: Direct

Name: nuoN

Synonym: Nmul_A1025

Alternate gene names: 82702154

Gene position: 1187035-1188558 (Clockwise)

Preceding gene: 82702153

Following gene: 82702159

Centisome position: 37.28

GC content: 55.77

Gene sequence:

>1524_bases
ATGAATCCGATGCCCTCTGCACTACCCTCCGATTTTCTGCACGTGGACCTCGTGACCCTGTCGCCGCTCATTCTCCTTGC
CGCAGCAGCGGTAGTGGTGATGCTGACCGCAGCCTTTTACCGTCATCCCCGACCGGTCATGATATTGACGCTCGCCGGAC
TGGTTCTGTCATTTATGGCATTGTTCCTGTCCCAAGGCACGGCGTCTTCTCAGGTCACAACTCTGCTGATACTGGATCAG
TATGCATTGTTTTTTATCGGACTCATCGTTGTCGCGACCTTTGTCGTCGCGATATTGTGTTACCGCTACTTCGGCGGAGG
CGAAAGCCGGCATGAAGCGCTTTACATCCTGTTACTGCTGGCTGCCCTTGGTGGAGGGGTTCTCGTGGCAAGCAGCCATT
TTGCCTCGTTTCTCCTGGGTCTGGAACTGCTCAGCATTTCGCTGTTTGCATTGATCGCCTATCCACGGTTCACAGAGCAT
CCCCTCGAAGCAGGAATCAAGTACCTGATCCTCGCCGGATTCTCATCCGGGTTGCTCCTGTTCGGAATGGCGCTGGTTTA
TGCGCAGCTCGGGACGATGCAGTTTGTGAAAATCGGGACAATGCTTGCTGCGCCCGGCGCGGCGCTGGAACTCTATGGGT
TGGCGGGGCTTGCGCTGATTGTAACCGGTGTCGGATTCAAACTGGCGCTGGTGCCCTTCCACATGTGGACTCCGGATGTA
TATGAAGGTGCGCCTGTGCCGATTACCGCGTTCATCGCCACTGCTTCAAAGGGCGCCATGCTTGTCCTGCTGCTGCGCTA
TTTCCTCATGGCAGGGGCGCACCAGTCGCATTCGATCACATTCGCATTGAGCCTGATTGCCGTCGCGACGATCCTGGTTG
GCAATCTGCTCGCACTGTTACAGAATAACATCAAGCGGATTCTTGCCTATTCCTCGATTGCACAGCTTGGCTATCTGCTG
GTCGGGTTTCTGGCCTTTGACCAGCTGGCAATCGAGGCGGTAGCTTATTTTCTGACAGCCTATTTCGTCACCATGCTGGG
CGCCTTCGGTGTGGTAACGGTATTGTCCGAGGGGTTCAATGGCGGATCCGCTGGGGAATTCCATGATGCAGGGGAAAAGG
ATAGTGACAGGCTGGCAGATTATGCGGGTCTGTTCTGGCACAGACCGTGGCTGGCGGGAGTGTTTACCGCCATGCTGCTG
TCGTTGGCCGGAATTCCCCTGACAATGGGTTTTATCGGGAAGTTCTATATAGTGACGGCCGGGGTGGAAGCCTCGTTATG
GATGCCCGTGATTACCCTGGTTATCGGCAGCATCATCGGGCTGTTCTATTATATGCGCATTATCGCTGTGATGTATGGGT
GGGGCCCTGAGGCAGCCGGTGAAGCAATCATGCTGCGCGCTGCTTCGCCCTCCTTTGCGGAAAGCGCGACGCTGGCAGCG
CTGGCGTTATTGCTTATATGGCTTGGCATCTTTCCGGCTCAGCTTATCGGTGTGCTTGAAGGAGCGGGAGGAGGCTTGAC
CTGA

Upstream 100 bases:

>100_bases
TATGGCTGGGCCTGTATCCCCAGCCGGTCCTGAATGCCGCGCCAAACCCCGCAAACAGTCCGCCTGCGATTGCTGTTGCC
CACCATGAGGTCAATGTGGA

Downstream 100 bases:

>100_bases
TTGCCGGTACTTCGTCTATTTGTCCCCATCTTGCTGTCTGCTTCACTGTCTGTCCTGTCGCCTGCCCTCTTTTTTGTCAT
TGAATGGCTGCGCAGGCATC

Product: proton-translocating NADH-quinone oxidoreductase, chain N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N

Number of amino acids: Translated: 507; Mature: 507

Protein sequence:

>507_residues
MNPMPSALPSDFLHVDLVTLSPLILLAAAAVVVMLTAAFYRHPRPVMILTLAGLVLSFMALFLSQGTASSQVTTLLILDQ
YALFFIGLIVVATFVVAILCYRYFGGGESRHEALYILLLLAALGGGVLVASSHFASFLLGLELLSISLFALIAYPRFTEH
PLEAGIKYLILAGFSSGLLLFGMALVYAQLGTMQFVKIGTMLAAPGAALELYGLAGLALIVTGVGFKLALVPFHMWTPDV
YEGAPVPITAFIATASKGAMLVLLLRYFLMAGAHQSHSITFALSLIAVATILVGNLLALLQNNIKRILAYSSIAQLGYLL
VGFLAFDQLAIEAVAYFLTAYFVTMLGAFGVVTVLSEGFNGGSAGEFHDAGEKDSDRLADYAGLFWHRPWLAGVFTAMLL
SLAGIPLTMGFIGKFYIVTAGVEASLWMPVITLVIGSIIGLFYYMRIIAVMYGWGPEAAGEAIMLRAASPSFAESATLAA
LALLLIWLGIFPAQLIGVLEGAGGGLT

Sequences:

>Translated_507_residues
MNPMPSALPSDFLHVDLVTLSPLILLAAAAVVVMLTAAFYRHPRPVMILTLAGLVLSFMALFLSQGTASSQVTTLLILDQ
YALFFIGLIVVATFVVAILCYRYFGGGESRHEALYILLLLAALGGGVLVASSHFASFLLGLELLSISLFALIAYPRFTEH
PLEAGIKYLILAGFSSGLLLFGMALVYAQLGTMQFVKIGTMLAAPGAALELYGLAGLALIVTGVGFKLALVPFHMWTPDV
YEGAPVPITAFIATASKGAMLVLLLRYFLMAGAHQSHSITFALSLIAVATILVGNLLALLQNNIKRILAYSSIAQLGYLL
VGFLAFDQLAIEAVAYFLTAYFVTMLGAFGVVTVLSEGFNGGSAGEFHDAGEKDSDRLADYAGLFWHRPWLAGVFTAMLL
SLAGIPLTMGFIGKFYIVTAGVEASLWMPVITLVIGSIIGLFYYMRIIAVMYGWGPEAAGEAIMLRAASPSFAESATLAA
LALLLIWLGIFPAQLIGVLEGAGGGLT
>Mature_507_residues
MNPMPSALPSDFLHVDLVTLSPLILLAAAAVVVMLTAAFYRHPRPVMILTLAGLVLSFMALFLSQGTASSQVTTLLILDQ
YALFFIGLIVVATFVVAILCYRYFGGGESRHEALYILLLLAALGGGVLVASSHFASFLLGLELLSISLFALIAYPRFTEH
PLEAGIKYLILAGFSSGLLLFGMALVYAQLGTMQFVKIGTMLAAPGAALELYGLAGLALIVTGVGFKLALVPFHMWTPDV
YEGAPVPITAFIATASKGAMLVLLLRYFLMAGAHQSHSITFALSLIAVATILVGNLLALLQNNIKRILAYSSIAQLGYLL
VGFLAFDQLAIEAVAYFLTAYFVTMLGAFGVVTVLSEGFNGGSAGEFHDAGEKDSDRLADYAGLFWHRPWLAGVFTAMLL
SLAGIPLTMGFIGKFYIVTAGVEASLWMPVITLVIGSIIGLFYYMRIIAVMYGWGPEAAGEAIMLRAASPSFAESATLAA
LALLLIWLGIFPAQLIGVLEGAGGGLT

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family

Homologues:

Organism=Escherichia coli, GI145693160, Length=490, Percent_Identity=43.469387755102, Blast_Score=364, Evalue=1e-102,
Organism=Escherichia coli, GI1788829, Length=458, Percent_Identity=29.4759825327511, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788831, Length=288, Percent_Identity=25.6944444444444, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788614, Length=275, Percent_Identity=26.9090909090909, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUON_NITMU (Q2YA93)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411720.1
- STRING:   Q2YA93
- GeneID:   3786550
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A1025
- HOGENOM:   HBG747830
- OMA:   FENTIIL
- PhylomeDB:   Q2YA93
- ProtClustDB:   CLSK744124
- BioCyc:   NMUL323848:NMUL_A1025-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00445
- InterPro:   IPR010096
- InterPro:   IPR001750
- TIGRFAMs:   TIGR01770

Pfam domain/function: PF00361 Oxidored_q1

EC number: =1.6.99.5

Molecular weight: Translated: 53747; Mature: 53747

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12bda5e8)-; HASH(0x12501944)-; HASH(0x122be5b0)-; HASH(0x12d3421c)-; HASH(0x10c33d48)-; HASH(0x12eeeb28)-; HASH(0x1278a294)-; HASH(0x128a1728)-; HASH(0x11ecfa60)-; HASH(0x109cb474)-; HASH(0x12d6cf40)-; HASH(0x11ca5304)-; HASH(0x12c3dfc8)-; HASH(0x12a38914)-; HASH(0x10a146d8)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPMPSALPSDFLHVDLVTLSPLILLAAAAVVVMLTAAFYRHPRPVMILTLAGLVLSFMA
CCCCCCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LFLSQGTASSQVTTLLILDQYALFFIGLIVVATFVVAILCYRYFGGGESRHEALYILLLL
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
AALGGGVLVASSHFASFLLGLELLSISLFALIAYPRFTEHPLEAGIKYLILAGFSSGLLL
HHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCHHHHHHHCCCCHHHH
FGMALVYAQLGTMQFVKIGTMLAAPGAALELYGLAGLALIVTGVGFKLALVPFHMWTPDV
HHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHEEEHCCCCCCC
YEGAPVPITAFIATASKGAMLVLLLRYFLMAGAHQSHSITFALSLIAVATILVGNLLALL
CCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QNNIKRILAYSSIAQLGYLLVGFLAFDQLAIEAVAYFLTAYFVTMLGAFGVVTVLSEGFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GGSAGEFHDAGEKDSDRLADYAGLFWHRPWLAGVFTAMLLSLAGIPLTMGFIGKFYIVTA
CCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEE
GVEASLWMPVITLVIGSIIGLFYYMRIIAVMYGWGPEAAGEAIMLRAASPSFAESATLAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHH
LALLLIWLGIFPAQLIGVLEGAGGGLT
HHHHHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure
MNPMPSALPSDFLHVDLVTLSPLILLAAAAVVVMLTAAFYRHPRPVMILTLAGLVLSFMA
CCCCCCCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LFLSQGTASSQVTTLLILDQYALFFIGLIVVATFVVAILCYRYFGGGESRHEALYILLLL
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
AALGGGVLVASSHFASFLLGLELLSISLFALIAYPRFTEHPLEAGIKYLILAGFSSGLLL
HHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCHHHHHHHCCCCHHHH
FGMALVYAQLGTMQFVKIGTMLAAPGAALELYGLAGLALIVTGVGFKLALVPFHMWTPDV
HHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHEEEHCCCCCCC
YEGAPVPITAFIATASKGAMLVLLLRYFLMAGAHQSHSITFALSLIAVATILVGNLLALL
CCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QNNIKRILAYSSIAQLGYLLVGFLAFDQLAIEAVAYFLTAYFVTMLGAFGVVTVLSEGFN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GGSAGEFHDAGEKDSDRLADYAGLFWHRPWLAGVFTAMLLSLAGIPLTMGFIGKFYIVTA
CCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEE
GVEASLWMPVITLVIGSIIGLFYYMRIIAVMYGWGPEAAGEAIMLRAASPSFAESATLAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHH
LALLLIWLGIFPAQLIGVLEGAGGGLT
HHHHHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA