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The map label for this gene is frr

Identifier: 82701793

GI number: 82701793

Start: 755531

End: 756088

Strand: Direct

Name: frr

Synonym: Nmul_A0660

Alternate gene names: 82701793

Gene position: 755531-756088 (Clockwise)

Preceding gene: 82701792

Following gene: 82701794

Centisome position: 23.73

GC content: 53.23

Gene sequence:

>558_bases
ATGATTGCCGAGATAAAAAAATCCGCCGAGCAGAAAATGCAGAAAAGCCTGGAAGCATTGAAACTGGACCTGGGCAAGAT
ACGAACCGGACGCGCCCATACAGGTCTGCTGGATCACGTTACTGTGGATTATTACGGGAACCCCACCGCAATCAACCAGG
TGGCAAACATCAGCCTTGCGGATGCCCGCACCATTACCGTAGCGCCATGGGAAAAGAAGATGCTGGGGGCGATAGAAAAA
GCTATCCGCAATTCAGACCTGGGTTTGAATCCCACGACCGTAGGCGAATTGATCCGCGTACCCATGCCGCCGCTTACCGA
GGAACGGAGGCGCGATCTCACCAAGGTGGTAAAGCATGAGGGGGAAGCGGCGCGCGTGGCGATGCGAAACATTCGCCGGG
ACGCAAATGCGCACCTGAAGGACTTGCTCAAGGAAAAAAAGATTGCCGAAGATGAAGAACGCAAGGGGCAGGAGGATATC
CAGAAACTTACCGATCGCTATATTGCGGATATAGACAAGCTCCTTCAGGCCAAAGAAGCCGAACTGATGGCCGTATAA

Upstream 100 bases:

>100_bases
AGTAGGGGCCATAGCTTGGAATTGCCGTCATCGTGCCGCGGCATGGACGCCAAACAGTGACGTCCCGGGTTATATATCAT
TTACGTCATTTCTAACTATC

Downstream 100 bases:

>100_bases
TGGAGTAATATTGCGGGAAGTGACAGTACATGTCTCCGCTTGGCTGTTCTGGAAAGCCGGACCTGAAATAAAAATACCCT
TGATTTCAATTTTGAATCTC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MIAEIKKSAEQKMQKSLEALKLDLGKIRTGRAHTGLLDHVTVDYYGNPTAINQVANISLADARTITVAPWEKKMLGAIEK
AIRNSDLGLNPTTVGELIRVPMPPLTEERRRDLTKVVKHEGEAARVAMRNIRRDANAHLKDLLKEKKIAEDEERKGQEDI
QKLTDRYIADIDKLLQAKEAELMAV

Sequences:

>Translated_185_residues
MIAEIKKSAEQKMQKSLEALKLDLGKIRTGRAHTGLLDHVTVDYYGNPTAINQVANISLADARTITVAPWEKKMLGAIEK
AIRNSDLGLNPTTVGELIRVPMPPLTEERRRDLTKVVKHEGEAARVAMRNIRRDANAHLKDLLKEKKIAEDEERKGQEDI
QKLTDRYIADIDKLLQAKEAELMAV
>Mature_185_residues
MIAEIKKSAEQKMQKSLEALKLDLGKIRTGRAHTGLLDHVTVDYYGNPTAINQVANISLADARTITVAPWEKKMLGAIEK
AIRNSDLGLNPTTVGELIRVPMPPLTEERRRDLTKVVKHEGEAARVAMRNIRRDANAHLKDLLKEKKIAEDEERKGQEDI
QKLTDRYIADIDKLLQAKEAELMAV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=176, Percent_Identity=32.9545454545455, Blast_Score=84, Evalue=6e-17,
Organism=Homo sapiens, GI291042689, Length=152, Percent_Identity=33.5526315789474, Blast_Score=75, Evalue=4e-14,
Organism=Escherichia coli, GI1786368, Length=183, Percent_Identity=55.1912568306011, Blast_Score=211, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24661488, Length=179, Percent_Identity=30.1675977653631, Blast_Score=81, Evalue=4e-16,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_NITMU (Q2YBA4)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411359.1
- ProteinModelPortal:   Q2YBA4
- SMR:   Q2YBA4
- STRING:   Q2YBA4
- GeneID:   3785145
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A0660
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   Q2YBA4
- ProtClustDB:   PRK00083
- BioCyc:   NMUL323848:NMUL_A0660-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20798; Mature: 20798

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAEIKKSAEQKMQKSLEALKLDLGKIRTGRAHTGLLDHVTVDYYGNPTAINQVANISLA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHEEEEECCCCHHHHHHHCCEEC
DARTITVAPWEKKMLGAIEKAIRNSDLGLNPTTVGELIRVPMPPLTEERRRDLTKVVKHE
CCCEEEECCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
GEAARVAMRNIRRDANAHLKDLLKEKKIAEDEERKGQEDIQKLTDRYIADIDKLLQAKEA
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ELMAV
HHHCC
>Mature Secondary Structure
MIAEIKKSAEQKMQKSLEALKLDLGKIRTGRAHTGLLDHVTVDYYGNPTAINQVANISLA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHEEEEECCCCHHHHHHHCCEEC
DARTITVAPWEKKMLGAIEKAIRNSDLGLNPTTVGELIRVPMPPLTEERRRDLTKVVKHE
CCCEEEECCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
GEAARVAMRNIRRDANAHLKDLLKEKKIAEDEERKGQEDIQKLTDRYIADIDKLLQAKEA
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ELMAV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA