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The map label for this gene is serB [H]

Identifier: 82701769

GI number: 82701769

Start: 726339

End: 727169

Strand: Reverse

Name: serB [H]

Synonym: Nmul_A0636

Alternate gene names: 82701769

Gene position: 727169-726339 (Counterclockwise)

Preceding gene: 82701771

Following gene: 82701765

Centisome position: 22.84

GC content: 53.19

Gene sequence:

>831_bases
ATGAACCTCATCATACAAGGACTCGAAATCCAGAACAGCGATTTAAGGGAACTGGCGAAACTGGTCGACGCAAACCATAT
CGAACGTATCACGGGGCAAGCCTTCCGGCTTGAAAATGCAGCCCGGCGGGAAGAGGTGGCCGCATATTGTGCTGAAGCGG
ACCTTGATTTTGCTTTTGTCGACCCATCGGCGCGGCTATCAGATTTTGGTCTGGTTGCGATGGATATGGATTCGACCCTC
CTCGCGATCGAATCCATTGATGAGATCGCGGATATGCAGGGCGTAAAGGCGCAGGTGGCGGAAATCACGCAGAGGGCCAT
GCGTGGGGAAATCGTCTTTGCAGAAAGCCTGCGGCTCCGAACCGCCTTGCTGGAGGGACTGGATGAAGACGCCCTGCAGC
GGGTATATGACGAACGGGTTCGGTTGAGTCCCGGAGCGGAAAAGATGCTGCAACGCATGAAATCCGCCGGTCTCAAAACC
ATGGTCATTTCCGGTGGCTTCACTTTTTTTACTGACAGAGTAAAAGCCAGACTGGATCTCGATTATGCTGCCGCCAATCG
CTTTGAAGTCTCAAACGGCAAACTGACAGGGAAGGTGTTGGGAGATATCATCGGAGCGACCGGAAAAGGGGAAGTGCTGA
AAAAAGTGCGCGAAGAACTGGGACTGAAGCGGGAACAGGTCATTGCTATCGGCGATGGAGCCAATGACCTCAAGATGATG
GAAGAGGCAGGGGTCAGCATTGCTTATCATGCAAAACCGGTGGTACAGGCGAAAGCTACTTATGCACTCAACCATGTCGG
ACTCGATGGCGTAGTCAACCTGTTCCGGTGA

Upstream 100 bases:

>100_bases
CTCCACGCCCATTCGCAGGAAACGCTACTGCCGAACGGAGTTCCTTCGGCTTTTCTTGCACGGCTGTCGCACATTCTTGA
CAATAATTGGAACAACAAAC

Downstream 100 bases:

>100_bases
ATGATGTCTGGAGTAGCCGGAACCGGTCCACTTCCAGCCGACCTCCCTAATAGCTGAACGCCGCCTCAACCAAGTAGGTG
CGTTGCGGATAGGGGTGAAA

Product: phosphoserine phosphatase SerB

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MNLIIQGLEIQNSDLRELAKLVDANHIERITGQAFRLENAARREEVAAYCAEADLDFAFVDPSARLSDFGLVAMDMDSTL
LAIESIDEIADMQGVKAQVAEITQRAMRGEIVFAESLRLRTALLEGLDEDALQRVYDERVRLSPGAEKMLQRMKSAGLKT
MVISGGFTFFTDRVKARLDLDYAAANRFEVSNGKLTGKVLGDIIGATGKGEVLKKVREELGLKREQVIAIGDGANDLKMM
EEAGVSIAYHAKPVVQAKATYALNHVGLDGVVNLFR

Sequences:

>Translated_276_residues
MNLIIQGLEIQNSDLRELAKLVDANHIERITGQAFRLENAARREEVAAYCAEADLDFAFVDPSARLSDFGLVAMDMDSTL
LAIESIDEIADMQGVKAQVAEITQRAMRGEIVFAESLRLRTALLEGLDEDALQRVYDERVRLSPGAEKMLQRMKSAGLKT
MVISGGFTFFTDRVKARLDLDYAAANRFEVSNGKLTGKVLGDIIGATGKGEVLKKVREELGLKREQVIAIGDGANDLKMM
EEAGVSIAYHAKPVVQAKATYALNHVGLDGVVNLFR
>Mature_276_residues
MNLIIQGLEIQNSDLRELAKLVDANHIERITGQAFRLENAARREEVAAYCAEADLDFAFVDPSARLSDFGLVAMDMDSTL
LAIESIDEIADMQGVKAQVAEITQRAMRGEIVFAESLRLRTALLEGLDEDALQRVYDERVRLSPGAEKMLQRMKSAGLKT
MVISGGFTFFTDRVKARLDLDYAAANRFEVSNGKLTGKVLGDIIGATGKGEVLKKVREELGLKREQVIAIGDGANDLKMM
EEAGVSIAYHAKPVVQAKATYALNHVGLDGVVNLFR

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=182, Percent_Identity=31.8681318681319, Blast_Score=92, Evalue=4e-19,
Organism=Escherichia coli, GI1790849, Length=224, Percent_Identity=45.0892857142857, Blast_Score=189, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6321647, Length=195, Percent_Identity=42.0512820512821, Blast_Score=142, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24661601, Length=203, Percent_Identity=27.5862068965517, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 30261; Mature: 30261

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLIIQGLEIQNSDLRELAKLVDANHIERITGQAFRLENAARREEVAAYCAEADLDFAFV
CCEEEECCCCCCCHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCEEEE
DPSARLSDFGLVAMDMDSTLLAIESIDEIADMQGVKAQVAEITQRAMRGEIVFAESLRLR
CCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEHHHHHHH
TALLEGLDEDALQRVYDERVRLSPGAEKMLQRMKSAGLKTMVISGGFTFFTDRVKARLDL
HHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCC
DYAAANRFEVSNGKLTGKVLGDIIGATGKGEVLKKVREELGLKREQVIAIGDGANDLKMM
HHHHCCCEECCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHEEEEECCCCHHHHHH
EEAGVSIAYHAKPVVQAKATYALNHVGLDGVVNLFR
HHCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHCC
>Mature Secondary Structure
MNLIIQGLEIQNSDLRELAKLVDANHIERITGQAFRLENAARREEVAAYCAEADLDFAFV
CCEEEECCCCCCCHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCEEEE
DPSARLSDFGLVAMDMDSTLLAIESIDEIADMQGVKAQVAEITQRAMRGEIVFAESLRLR
CCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEHHHHHHH
TALLEGLDEDALQRVYDERVRLSPGAEKMLQRMKSAGLKTMVISGGFTFFTDRVKARLDL
HHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCC
DYAAANRFEVSNGKLTGKVLGDIIGATGKGEVLKKVREELGLKREQVIAIGDGANDLKMM
HHHHCCCEECCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHEEEEECCCCHHHHHH
EEAGVSIAYHAKPVVQAKATYALNHVGLDGVVNLFR
HHCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]