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The map label for this gene is tagO [H]

Identifier: 82701765

GI number: 82701765

Start: 719489

End: 720547

Strand: Reverse

Name: tagO [H]

Synonym: Nmul_A0632

Alternate gene names: 82701765

Gene position: 720547-719489 (Counterclockwise)

Preceding gene: 82701769

Following gene: 82701764

Centisome position: 22.63

GC content: 53.73

Gene sequence:

>1059_bases
ATGGACTGGCATGGGCTGAAGTATGCATGCATGCGCCTCATAAGTCATCAAGGCTATAATCCGATCATGAATTCCGGCTC
CCCGATTTTATATCTGATCCCGCCATTCATAGCGTTTGCCGTGTCGCTAGGAACGATTTCGTGTCTGATCAAAGGGAATA
TTCTCAAAATCCTGGACCAGCCGAATTCCCGATCGCTGCATACTCGTCCCGTTCCCCGCACGGGAGGCCTGGGGCTGATG
TCGGGGATTTTCGTCTCATGGACGTTTCTGCCGGTAAAACCGCCGGTGTCGATATGGGTTGCGATTGTGCTGCTGGTAAC
GATATCTTTCGCCGATGATGTACGCAGCCTGCCGGTATGGCCAAGGCTCGTCATTTACACAGGACTTGGAATCTGGTTTT
CTGCCGTAACCCTTGCTGCCACCTACGGCTGGCTTGTCGCCGTAGCAGCCGCACTCTGCATTACCTGGATGCTCAACCTC
TATAATTTCATGGACGGTTCGGATGGACTGGCAGGCGGCATGACACTGATCGGTTTCAGTTGCTACGGAGCGACAGCATG
GATTTCCGGAAACGAGGCCTTTGCAATCGCCAACTTCTGTATTGCCGCAGCAGCAGGAGCTTTTCTGTTGTTTAATTTTC
ATCCCGCACGCATTTTCATGGGAGACGCGGGCTCGATTCCGCTCGGGTTCCTTGCTGCAGCATTAGGTATGATGGGATGG
ATAAATGGCTGCTGGCCTCCATGGTTTCCCTTGCTCGTATTTTCGCCGTTTATCGTCGATGCTTCCGTCACCTTGATAAA
ACGCGGACTGCGAGGCGAAAAAATCTGGCGAGCGCATCGCGAGCATTATTACCAGCGCCTAGTGCGAAGCGGTCTGGGTC
ATCGCAATACGGCTCTGATCGGCTACGTTCTGATGTCAGCCACAGCCATCAGCGCCCTCTGGGCGACTCAGCAGCACACG
AACGTTCAGTTCGGAATGGTGACCGCGTGGATCGGAATTTATCTGGTCATGATATGCCTTTGCGATCGCCGTCTGCGGCA
TGCCCCGGATAGTCCATAG

Upstream 100 bases:

>100_bases
TCGAACCTGATCTGGGACTGGAAGCGGGCTGTGCAGGGCAGATAAGGTGCTGGCGGGGGGAGATCGAAAATCGGTATTAT
TTACCTCATTCTCCCGCGCA

Downstream 100 bases:

>100_bases
CATGCCCGCGCCCAAACTCAACATAAGGACGGTTATTGCATTCGGGCATGATGTTGTAGCTGCCGCCATCGCCTGGTCCC
TGGCTTATCTGTTCCGCTTC

Product: glycosyl transferase family protein

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MDWHGLKYACMRLISHQGYNPIMNSGSPILYLIPPFIAFAVSLGTISCLIKGNILKILDQPNSRSLHTRPVPRTGGLGLM
SGIFVSWTFLPVKPPVSIWVAIVLLVTISFADDVRSLPVWPRLVIYTGLGIWFSAVTLAATYGWLVAVAAALCITWMLNL
YNFMDGSDGLAGGMTLIGFSCYGATAWISGNEAFAIANFCIAAAAGAFLLFNFHPARIFMGDAGSIPLGFLAAALGMMGW
INGCWPPWFPLLVFSPFIVDASVTLIKRGLRGEKIWRAHREHYYQRLVRSGLGHRNTALIGYVLMSATAISALWATQQHT
NVQFGMVTAWIGIYLVMICLCDRRLRHAPDSP

Sequences:

>Translated_352_residues
MDWHGLKYACMRLISHQGYNPIMNSGSPILYLIPPFIAFAVSLGTISCLIKGNILKILDQPNSRSLHTRPVPRTGGLGLM
SGIFVSWTFLPVKPPVSIWVAIVLLVTISFADDVRSLPVWPRLVIYTGLGIWFSAVTLAATYGWLVAVAAALCITWMLNL
YNFMDGSDGLAGGMTLIGFSCYGATAWISGNEAFAIANFCIAAAAGAFLLFNFHPARIFMGDAGSIPLGFLAAALGMMGW
INGCWPPWFPLLVFSPFIVDASVTLIKRGLRGEKIWRAHREHYYQRLVRSGLGHRNTALIGYVLMSATAISALWATQQHT
NVQFGMVTAWIGIYLVMICLCDRRLRHAPDSP
>Mature_352_residues
MDWHGLKYACMRLISHQGYNPIMNSGSPILYLIPPFIAFAVSLGTISCLIKGNILKILDQPNSRSLHTRPVPRTGGLGLM
SGIFVSWTFLPVKPPVSIWVAIVLLVTISFADDVRSLPVWPRLVIYTGLGIWFSAVTLAATYGWLVAVAAALCITWMLNL
YNFMDGSDGLAGGMTLIGFSCYGATAWISGNEAFAIANFCIAAAAGAFLLFNFHPARIFMGDAGSIPLGFLAAALGMMGW
INGCWPPWFPLLVFSPFIVDASVTLIKRGLRGEKIWRAHREHYYQRLVRSGLGHRNTALIGYVLMSATAISALWATQQHT
NVQFGMVTAWIGIYLVMICLCDRRLRHAPDSP

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=266, Percent_Identity=25.5639097744361, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 38587; Mature: 38587

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWHGLKYACMRLISHQGYNPIMNSGSPILYLIPPFIAFAVSLGTISCLIKGNILKILDQ
CCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCEEEEECC
PNSRSLHTRPVPRTGGLGLMSGIFVSWTFLPVKPPVSIWVAIVLLVTISFADDVRSLPVW
CCCCCCCCCCCCCCCCCHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCC
PRLVIYTGLGIWFSAVTLAATYGWLVAVAAALCITWMLNLYNFMDGSDGLAGGMTLIGFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHEEEE
CYGATAWISGNEAFAIANFCIAAAAGAFLLFNFHPARIFMGDAGSIPLGFLAAALGMMGW
ECCCEEEECCCCHHHHHHHHHHHHHHHHEEEECCCCEEEECCCCCCCHHHHHHHHHHHHH
INGCWPPWFPLLVFSPFIVDASVTLIKRGLRGEKIWRAHREHYYQRLVRSGLGHRNTALI
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
GYVLMSATAISALWATQQHTNVQFGMVTAWIGIYLVMICLCDRRLRHAPDSP
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDWHGLKYACMRLISHQGYNPIMNSGSPILYLIPPFIAFAVSLGTISCLIKGNILKILDQ
CCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCEEEEECC
PNSRSLHTRPVPRTGGLGLMSGIFVSWTFLPVKPPVSIWVAIVLLVTISFADDVRSLPVW
CCCCCCCCCCCCCCCCCHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCC
PRLVIYTGLGIWFSAVTLAATYGWLVAVAAALCITWMLNLYNFMDGSDGLAGGMTLIGFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHEEEE
CYGATAWISGNEAFAIANFCIAAAAGAFLLFNFHPARIFMGDAGSIPLGFLAAALGMMGW
ECCCEEEECCCCHHHHHHHHHHHHHHHHEEEECCCCEEEECCCCCCCHHHHHHHHHHHHH
INGCWPPWFPLLVFSPFIVDASVTLIKRGLRGEKIWRAHREHYYQRLVRSGLGHRNTALI
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
GYVLMSATAISALWATQQHTNVQFGMVTAWIGIYLVMICLCDRRLRHAPDSP
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]