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The map label for this gene is tpx [H]

Identifier: 82701345

GI number: 82701345

Start: 224579

End: 225076

Strand: Reverse

Name: tpx [H]

Synonym: Nmul_A0211

Alternate gene names: 82701345

Gene position: 225076-224579 (Counterclockwise)

Preceding gene: 82701346

Following gene: 82701344

Centisome position: 7.07

GC content: 55.02

Gene sequence:

>498_bases
ATGGTTACCCTAGCCGGCAATCCCATCAAAGTTGAAGGCACCTTCCCCAAGGTAGGCGACAAGGCACCCGATTTCTCTCT
GGTAAACAGGGATTTGAAAGATGTCACCCTGGCCGATTTTGCGGGCAAGAAAAAAGTGCTCAACATTGTTCCCAGCCTTG
ATACCCCGGTCTGCGCCATGTCCACCCGCAAGTTCAACGAGCAGGCCAGCAATATGGAAAACACGGTGGTGTTGATCATT
GCTGCCGATCTGCCCTTCGCAATGAGCCGCTTTTGCGACATGGAAGGACTCGACAAGGTGGTACCGCTTTCCACGATGCG
CGGGGCGGAATTCATGAAAAACTACGGGGTGGCGATTACGGACAGTCCTCTTGCGGGGATCACGGCCCGGGCTGTCGTGG
TCCTGGATGAAAACGACAAGGTCACCCATGCGCAACTTGTCCCGGAAATCAAGGAAGAGCCGGATTATGAGGCGGCGCTG
AAGGCACTGGAATCCTGA

Upstream 100 bases:

>100_bases
AAAATTATGTCACGCAACTGGGCGAAGTCATCAGGAATTCATAGCACCGATATCGCATTGGACGTTTAGCAGCCATCCCA
CATCTTAAAGGAGAAACAGT

Downstream 100 bases:

>100_bases
ACAGGACCGACATGTGGAATGCATCGCCTTTGGTCGATGAGGGGGTATCCGGCGCCTGCGGAATACGCGCCCTCCTACTC
GCGGCTCTGAGGCAGAGGAA

Product: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: oxidized thioredoxin; H2O [C]

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MVTLAGNPIKVEGTFPKVGDKAPDFSLVNRDLKDVTLADFAGKKKVLNIVPSLDTPVCAMSTRKFNEQASNMENTVVLII
AADLPFAMSRFCDMEGLDKVVPLSTMRGAEFMKNYGVAITDSPLAGITARAVVVLDENDKVTHAQLVPEIKEEPDYEAAL
KALES

Sequences:

>Translated_165_residues
MVTLAGNPIKVEGTFPKVGDKAPDFSLVNRDLKDVTLADFAGKKKVLNIVPSLDTPVCAMSTRKFNEQASNMENTVVLII
AADLPFAMSRFCDMEGLDKVVPLSTMRGAEFMKNYGVAITDSPLAGITARAVVVLDENDKVTHAQLVPEIKEEPDYEAAL
KALES
>Mature_165_residues
MVTLAGNPIKVEGTFPKVGDKAPDFSLVNRDLKDVTLADFAGKKKVLNIVPSLDTPVCAMSTRKFNEQASNMENTVVLII
AADLPFAMSRFCDMEGLDKVVPLSTMRGAEFMKNYGVAITDSPLAGITARAVVVLDENDKVTHAQLVPEIKEEPDYEAAL
KALES

Specific function: Has antioxidant activity. Could remove peroxides or H(2)O(2) [H]

COG id: COG2077

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1787584, Length=164, Percent_Identity=61.5853658536585, Blast_Score=211, Evalue=2e-56,

Paralogues:

None

Copy number: 2480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018219
- InterPro:   IPR002065
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: 1.11.1.- [C]

Molecular weight: Translated: 17858; Mature: 17858

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTLAGNPIKVEGTFPKVGDKAPDFSLVNRDLKDVTLADFAGKKKVLNIVPSLDTPVCAM
CEEECCCCEEEEECCCCCCCCCCCHHHHCCCCHHHHHHHHCCCCEEEEECCCCCCCCHHH
STRKFNEQASNMENTVVLIIAADLPFAMSRFCDMEGLDKVVPLSTMRGAEFMKNYGVAIT
HHHHHHHHHCCCCCEEEEEEECCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCEEEE
DSPLAGITARAVVVLDENDKVTHAQLVPEIKEEPDYEAALKALES
CCCCCCCEEEEEEEECCCCCEEHHHHCCHHHCCCCHHHHHHHHCC
>Mature Secondary Structure
MVTLAGNPIKVEGTFPKVGDKAPDFSLVNRDLKDVTLADFAGKKKVLNIVPSLDTPVCAM
CEEECCCCEEEEECCCCCCCCCCCHHHHCCCCHHHHHHHHCCCCEEEEECCCCCCCCHHH
STRKFNEQASNMENTVVLIIAADLPFAMSRFCDMEGLDKVVPLSTMRGAEFMKNYGVAIT
HHHHHHHHHCCCCCEEEEEEECCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCEEEE
DSPLAGITARAVVVLDENDKVTHAQLVPEIKEEPDYEAALKALES
CCCCCCCEEEEEEEECCCCCEEHHHHCCHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: reduced thioredoxin; H2O2 [C]

Specific reaction: reduced thioredoxin + H2O2 = oxidized thioredoxin + H2O [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]