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The map label for this gene is fabG [H]

Identifier: 78779735

GI number: 78779735

Start: 1266400

End: 1267161

Strand: Direct

Name: fabG [H]

Synonym: PMT9312_1351

Alternate gene names: 78779735

Gene position: 1266400-1267161 (Clockwise)

Preceding gene: 78779734

Following gene: 78779736

Centisome position: 74.09

GC content: 29.27

Gene sequence:

>762_bases
ATGAATTTAGATTTAAAAGATAAATTTATAATAATAGCTGGAGGACTTGGGGGTATTGGTCTAGAAACTGTAAAAGACTT
AATTTCTGAAGGTGCAGAAATTTCAATATTAACTCAAAATGAATCAAAATATATTGAATATTCAAAATACTTTGATGTAC
ATTTATTGGATTACGAATCAGAAGATTCTATTAAAGCCACCTTTGAATTTTTAATGAAAAACAGAAAGCCATCAGGGTTT
ATATCTTTTGTTGGTACTGGTAGATCGTCTAATAATGCTTTTCAAAATAAAGATGATGTTATCAAGATGTGGCAAGTTAA
CTATTTTGCCAACAGATTATTGGCAAAAATTTTTGTAGAGTCTACACGAAAAATTTTTGGAGATCCAAAAAATTCGGATT
ACTTTATTACTCTAACTGCATCAATAGCATCTAACCTTTTTATTAATTGCCCAACTGAATATTCAGTTTCAAAAATTGCA
TTAGTGAGATTATGCAAAGATTTATCTTGGAAATTAGCCCCTTACTATAGAGTAAATTGCATTTCTCCAGGTAATATTTT
CTTTAAAGGTGGTACGTGGGACAGAATACAAAAAGAAGGTAAAATTGATATTGATGAACTATTAAAAACAAAAGTTCCAT
CCAGAAGATTTGGAACCCCATCTGATATATCTAAATTTGCAGTATTTTTATCATCTCCCTTAGCATCATTTATAAATGGT
TCATGTATTAAAATTGATGGTGGCCAATCAACTTATACTTAG

Upstream 100 bases:

>100_bases
AAGATGTAATAGGACCAGTAATTTTTTTATTATCTAATGAAAGTAGCTATATCACTGGAACAGGTATAAATGTTGATGGT
GGGTGGTTATCAAAAGGATT

Downstream 100 bases:

>100_bases
AAATTGAAAAATTTTGATTTAAAAGAAGGTTACTATATTGTTACCGGCGGTCTTGGATTACTGGGGAAACAACATTGTGA
AGCTATAAGTAAATTCGGTG

Product: dehydrogenase with different specificities

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MNLDLKDKFIIIAGGLGGIGLETVKDLISEGAEISILTQNESKYIEYSKYFDVHLLDYESEDSIKATFEFLMKNRKPSGF
ISFVGTGRSSNNAFQNKDDVIKMWQVNYFANRLLAKIFVESTRKIFGDPKNSDYFITLTASIASNLFINCPTEYSVSKIA
LVRLCKDLSWKLAPYYRVNCISPGNIFFKGGTWDRIQKEGKIDIDELLKTKVPSRRFGTPSDISKFAVFLSSPLASFING
SCIKIDGGQSTYT

Sequences:

>Translated_253_residues
MNLDLKDKFIIIAGGLGGIGLETVKDLISEGAEISILTQNESKYIEYSKYFDVHLLDYESEDSIKATFEFLMKNRKPSGF
ISFVGTGRSSNNAFQNKDDVIKMWQVNYFANRLLAKIFVESTRKIFGDPKNSDYFITLTASIASNLFINCPTEYSVSKIA
LVRLCKDLSWKLAPYYRVNCISPGNIFFKGGTWDRIQKEGKIDIDELLKTKVPSRRFGTPSDISKFAVFLSSPLASFING
SCIKIDGGQSTYT
>Mature_253_residues
MNLDLKDKFIIIAGGLGGIGLETVKDLISEGAEISILTQNESKYIEYSKYFDVHLLDYESEDSIKATFEFLMKNRKPSGF
ISFVGTGRSSNNAFQNKDDVIKMWQVNYFANRLLAKIFVESTRKIFGDPKNSDYFITLTASIASNLFINCPTEYSVSKIA
LVRLCKDLSWKLAPYYRVNCISPGNIFFKGGTWDRIQKEGKIDIDELLKTKVPSRRFGTPSDISKFAVFLSSPLASFING
SCIKIDGGQSTYT

Specific function: 7-Alpha-Dehydroxylation Of Cholic Acid, Yielding Deoxycholic Acid And Lithocholic Acid, Respectively. Highest Affinity With Taurochenodeoxycholic Acid. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17536025, Length=268, Percent_Identity=26.4925373134328, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355319, Length=257, Percent_Identity=29.5719844357977, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 28428; Mature: 28428

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLDLKDKFIIIAGGLGGIGLETVKDLISEGAEISILTQNESKYIEYSKYFDVHLLDYES
CCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCEEEEEEEEEEEEECCCC
EDSIKATFEFLMKNRKPSGFISFVGTGRSSNNAFQNKDDVIKMWQVNYFANRLLAKIFVE
CCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
STRKIFGDPKNSDYFITLTASIASNLFINCPTEYSVSKIALVRLCKDLSWKLAPYYRVNC
HHHHHHCCCCCCCEEEEEEEHHHCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEE
ISPGNIFFKGGTWDRIQKEGKIDIDELLKTKVPSRRFGTPSDISKFAVFLSSPLASFING
ECCCCEEEECCCHHHHHCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
SCIKIDGGQSTYT
CEEEEECCCCCCC
>Mature Secondary Structure
MNLDLKDKFIIIAGGLGGIGLETVKDLISEGAEISILTQNESKYIEYSKYFDVHLLDYES
CCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCEEEEEEEEEEEEECCCC
EDSIKATFEFLMKNRKPSGFISFVGTGRSSNNAFQNKDDVIKMWQVNYFANRLLAKIFVE
CCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHH
STRKIFGDPKNSDYFITLTASIASNLFINCPTEYSVSKIALVRLCKDLSWKLAPYYRVNC
HHHHHHCCCCCCCEEEEEEEHHHCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEE
ISPGNIFFKGGTWDRIQKEGKIDIDELLKTKVPSRRFGTPSDISKFAVFLSSPLASFING
ECCCCEEEECCCHHHHHCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
SCIKIDGGQSTYT
CEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]