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The map label for this gene is sasA [H]

Identifier: 78779471

GI number: 78779471

Start: 999602

End: 1000720

Strand: Reverse

Name: sasA [H]

Synonym: PMT9312_1088

Alternate gene names: 78779471

Gene position: 1000720-999602 (Counterclockwise)

Preceding gene: 78779474

Following gene: 78779469

Centisome position: 58.55

GC content: 35.48

Gene sequence:

>1119_bases
TTGAATGATAAAAAAGAGCTTAAATTAATACTTGTAGCAGCTAGAAATCAACTTTCTAGTAGTGATATCAAATCTCTGAT
AGCTTATTTAGAATCAGATGATTGTAATTTTGAGATATCTCTTCAGATTTCCGAGCCCACAGAACAGCCTGAATTACTTG
AATTACATAGATTAGTTGCTATTCCCGCTCTCATAAAGGTTTCTCCAGCTCCAAAGCAAATATTTGCTGGAAGTAATATT
TTCTCACAGTTGCAGAAATGGTTGCCAAGGTGGAACCAGGAAGGCTTAACAAAAAATCTAGGGATTAATTTGCAACCATC
CAAAATTGATTCCATAAGAACTCAAAAAGAATACCTTCTGGAGGACGAACTTCTCGTTTTAAGACAAGAAAATGAGACTT
TAACAAAAAGAATAGAATCTCAGGAAAGATTATTAAGAATGGTCGCGCATGAATTAAGAACTCCCTTGACTGCTGCAACT
TTGGCTGTTCAAAGTCAAAAACTTGGACAAATAGACATTGCGAAATTGCAAGAGGTTATTAAAAGACGTTTAGAAGAGAT
TGAACTCTTATCTCAGGATCTTTTAGAGGTTGGAACAACAAAATGGGAAGCGTTGTTTAATCCTCAGAAAATTGACTTAG
GTAACATTAGTGCTGAAGCAATACTCGAATTAGAAAAATTCTGGAGATTGAGGGATATTGAAATTGATACTGATATTCCA
TCTGATCTGCCAAGTGTATTTGCGGATCAAAGAAGAATGAGGCAGGTATTTTTAAATTTAATTGAAAATGCTATTAAATT
TTCTAAAGACTATGGATCAATAAAAATTACAATGATTCATAAGACAAATCAATGGGTAGAAATAACAATTTGTGACAAAG
GTGCAGGTATTCCTTTGAACGAACAGAAAAGAATTTTTCTCGATAGAGTTAGGCTGCCACAGACTTCTGAAGGAACCTCA
GGATTTGGTATTGGGTTGTCTGTATGCAGGAGAATAGTACAAGTCCATGGAGGAAGAATATGGGTTGTATCTGAAATTGG
TGTAGGTTCTTGCTTCCATTTTACGGTTCCCGTGTGGCAAGGACAAAATAAAGAGCAACACTACTTGACGAAAGGCTAG

Upstream 100 bases:

>100_bases
ATAAGACCTATTTATTTCATAGCTTATCTGTAGAATAAAATTAAATATCTTAATGTGTTTATAAGGATTAACAGCTTTTC
AACACTTCAGGGGTAATCAT

Downstream 100 bases:

>100_bases
CCTTACTCTTAATTTTAATAAGCTGTTATGCTAATTTCCTGGCCCCATCGTCTAGAGGCCTAGGACACCTCCCTTTCACG
GAGGCGACAGGGGTTCGAAT

Product: adaptive-response sensory kinase

Products: NA

Alternate protein names: Synechococcus adaptive sensor protein A [H]

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MNDKKELKLILVAARNQLSSSDIKSLIAYLESDDCNFEISLQISEPTEQPELLELHRLVAIPALIKVSPAPKQIFAGSNI
FSQLQKWLPRWNQEGLTKNLGINLQPSKIDSIRTQKEYLLEDELLVLRQENETLTKRIESQERLLRMVAHELRTPLTAAT
LAVQSQKLGQIDIAKLQEVIKRRLEEIELLSQDLLEVGTTKWEALFNPQKIDLGNISAEAILELEKFWRLRDIEIDTDIP
SDLPSVFADQRRMRQVFLNLIENAIKFSKDYGSIKITMIHKTNQWVEITICDKGAGIPLNEQKRIFLDRVRLPQTSEGTS
GFGIGLSVCRRIVQVHGGRIWVVSEIGVGSCFHFTVPVWQGQNKEQHYLTKG

Sequences:

>Translated_372_residues
MNDKKELKLILVAARNQLSSSDIKSLIAYLESDDCNFEISLQISEPTEQPELLELHRLVAIPALIKVSPAPKQIFAGSNI
FSQLQKWLPRWNQEGLTKNLGINLQPSKIDSIRTQKEYLLEDELLVLRQENETLTKRIESQERLLRMVAHELRTPLTAAT
LAVQSQKLGQIDIAKLQEVIKRRLEEIELLSQDLLEVGTTKWEALFNPQKIDLGNISAEAILELEKFWRLRDIEIDTDIP
SDLPSVFADQRRMRQVFLNLIENAIKFSKDYGSIKITMIHKTNQWVEITICDKGAGIPLNEQKRIFLDRVRLPQTSEGTS
GFGIGLSVCRRIVQVHGGRIWVVSEIGVGSCFHFTVPVWQGQNKEQHYLTKG
>Mature_372_residues
MNDKKELKLILVAARNQLSSSDIKSLIAYLESDDCNFEISLQISEPTEQPELLELHRLVAIPALIKVSPAPKQIFAGSNI
FSQLQKWLPRWNQEGLTKNLGINLQPSKIDSIRTQKEYLLEDELLVLRQENETLTKRIESQERLLRMVAHELRTPLTAAT
LAVQSQKLGQIDIAKLQEVIKRRLEEIELLSQDLLEVGTTKWEALFNPQKIDLGNISAEAILELEKFWRLRDIEIDTDIP
SDLPSVFADQRRMRQVFLNLIENAIKFSKDYGSIKITMIHKTNQWVEITICDKGAGIPLNEQKRIFLDRVRLPQTSEGTS
GFGIGLSVCRRIVQVHGGRIWVVSEIGVGSCFHFTVPVWQGQNKEQHYLTKG

Specific function: May be involved in signal transduction. Participates in the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with kaiC. Required for robustness of the circadian rhythm of gene expression an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=248, Percent_Identity=29.0322580645161, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1788549, Length=243, Percent_Identity=29.6296296296296, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1786912, Length=232, Percent_Identity=28.8793103448276, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI48994928, Length=238, Percent_Identity=28.9915966386555, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI145693157, Length=251, Percent_Identity=28.2868525896414, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87081816, Length=245, Percent_Identity=30.2040816326531, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788393, Length=231, Percent_Identity=25.974025974026, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788713, Length=254, Percent_Identity=25.9842519685039, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789149, Length=233, Percent_Identity=30.0429184549356, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1788279, Length=238, Percent_Identity=29.8319327731092, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011649
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF07689 KaiB [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 42481; Mature: 42481

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDKKELKLILVAARNQLSSSDIKSLIAYLESDDCNFEISLQISEPTEQPELLELHRLVA
CCCHHHEEEEEEEHHCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHH
IPALIKVSPAPKQIFAGSNIFSQLQKWLPRWNQEGLTKNLGINLQPSKIDSIRTQKEYLL
HHHHEECCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCEECCHHHHHHHHHHHHHH
EDELLVLRQENETLTKRIESQERLLRMVAHELRTPLTAATLAVQSQKLGQIDIAKLQEVI
HCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHH
KRRLEEIELLSQDLLEVGTTKWEALFNPQKIDLGNISAEAILELEKFWRLRDIEIDTDIP
HHHHHHHHHHHHHHHHHCCCHHHHHCCCCEECCCCCCHHHHHHHHHHHHHCCEEECCCCC
SDLPSVFADQRRMRQVFLNLIENAIKFSKDYGSIKITMIHKTNQWVEITICDKGAGIPLN
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEEEECCCCCCCCC
EQKRIFLDRVRLPQTSEGTSGFGIGLSVCRRIVQVHGGRIWVVSEIGVGSCFHFTVPVWQ
CCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEEEEEC
GQNKEQHYLTKG
CCCCCCCCCCCC
>Mature Secondary Structure
MNDKKELKLILVAARNQLSSSDIKSLIAYLESDDCNFEISLQISEPTEQPELLELHRLVA
CCCHHHEEEEEEEHHCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHH
IPALIKVSPAPKQIFAGSNIFSQLQKWLPRWNQEGLTKNLGINLQPSKIDSIRTQKEYLL
HHHHEECCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCEECCHHHHHHHHHHHHHH
EDELLVLRQENETLTKRIESQERLLRMVAHELRTPLTAATLAVQSQKLGQIDIAKLQEVI
HCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHH
KRRLEEIELLSQDLLEVGTTKWEALFNPQKIDLGNISAEAILELEKFWRLRDIEIDTDIP
HHHHHHHHHHHHHHHHHCCCHHHHHCCCCEECCCCCCHHHHHHHHHHHHHCCEEECCCCC
SDLPSVFADQRRMRQVFLNLIENAIKFSKDYGSIKITMIHKTNQWVEITICDKGAGIPLN
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEEEECCCCCCCCC
EQKRIFLDRVRLPQTSEGTSGFGIGLSVCRRIVQVHGGRIWVVSEIGVGSCFHFTVPVWQ
CCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEEEEEC
GQNKEQHYLTKG
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA