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The map label for this gene is yeiR [H]

Identifier: 78484801

GI number: 78484801

Start: 513241

End: 514317

Strand: Reverse

Name: yeiR [H]

Synonym: Tcr_0456

Alternate gene names: 78484801

Gene position: 514317-513241 (Counterclockwise)

Preceding gene: 78484802

Following gene: 78484796

Centisome position: 21.19

GC content: 46.24

Gene sequence:

>1077_bases
ATGACGTCAAAGACCGCACTCAATATTATTTCTGGTCAACTAGGGGCCGGGAAAACCACCCTGCTCCAACAGTTACTCCG
ACAACGTCCCACACATGAAACGTGGGTTTTACTGGTCAATGAATTTGGTGCAGTGGGGATTGATGGGCCCATTTTAAGCA
GCCAAAATGACCACACCTTAGTCAAGCAGCTTCCCGGTGGTTGTATTTGCTGTACAGCACAAGGAGAACTTGAAGCCGCT
GTCTTAGACATTATTCAAACACAGCAACCGGACCGCATTCTGATTGAGCCGACAGGGCTTGGAGAACCTGAAAGCTTAGT
TGACTTATTCAAACAAGCCAAACTGCAAAGTCTGTGTGAGGTTCATTCACTTTTTTCGGTGCTTGATATGGCGCACACTC
AGTTAGAAGAACTTCAGACGTTATCGATTTTACAAAGCATGTTAACGATGGCAGACGTCATTGTGCTCAATAAAGTGGAC
TTAGTCTCTCCTGAACAAATCAGGTTATTCAAAGACTATATTGACACGCTGTACCCGCCTAAAAAAGCCGTCATCGTGAC
AGAACAAGCCGACGTGTCGTCCAGTTACTTGAATCATCCGCACTTTCACACGCCGGCTTATGTTGCTGCCCCCAGCTCTT
CTCATACGCTAGCACGACACAGTCAGCCGATGACGTCTATAAGCACTCAAGAGCCGTCTTACACACCTATCGAGTTGCCA
GGCCTTTTAGAAAGACGCTTCCAAACACACCTTAAAACAGAATCGATTGGTTGGGTGTTTAATGATGACGTTTGTTTTGA
GTGGTCTAAACTGTTGGCACTTTTTGAAAACTTGTCAGCAGGCACTTTTACACATCAGTCAAACATCATCGCGACGCCCA
TCAAACGTGCCAAGGGCATTTTCCGCGTCGGACACACCGCTCGAATGCTGTTTCAACTCGTTCACAACACCCTTACACGA
GAACTGATTGCCTACCGCAAGGACAGTCGCTTAGAGCTTTTGTTAGACATTAGCGCTGACTTTGACTATGAAGCATTTGA
GAAAGCATTACTCGATTGCATACAACGCCCTTCCTAA

Upstream 100 bases:

>100_bases
CTTTACGCGAGCAGATAAATGCCTTTACATGGCTAAATCAAATGGCCGAAATCGAGTGTATGGTGAAGCCGAATTATAAC
GCCTAGCTGACAGCTTTCAA

Downstream 100 bases:

>100_bases
CGATATTGACATCAGTCAGGCATAAAAAAACCGCCAGGCCTGGCGGTTTTTTATTATCACGTCGTTTAAACACTATGGCT
TAATTTGATTGCCTTCGGTG

Product: cobalamin synthesis protein/P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MTSKTALNIISGQLGAGKTTLLQQLLRQRPTHETWVLLVNEFGAVGIDGPILSSQNDHTLVKQLPGGCICCTAQGELEAA
VLDIIQTQQPDRILIEPTGLGEPESLVDLFKQAKLQSLCEVHSLFSVLDMAHTQLEELQTLSILQSMLTMADVIVLNKVD
LVSPEQIRLFKDYIDTLYPPKKAVIVTEQADVSSSYLNHPHFHTPAYVAAPSSSHTLARHSQPMTSISTQEPSYTPIELP
GLLERRFQTHLKTESIGWVFNDDVCFEWSKLLALFENLSAGTFTHQSNIIATPIKRAKGIFRVGHTARMLFQLVHNTLTR
ELIAYRKDSRLELLLDISADFDYEAFEKALLDCIQRPS

Sequences:

>Translated_358_residues
MTSKTALNIISGQLGAGKTTLLQQLLRQRPTHETWVLLVNEFGAVGIDGPILSSQNDHTLVKQLPGGCICCTAQGELEAA
VLDIIQTQQPDRILIEPTGLGEPESLVDLFKQAKLQSLCEVHSLFSVLDMAHTQLEELQTLSILQSMLTMADVIVLNKVD
LVSPEQIRLFKDYIDTLYPPKKAVIVTEQADVSSSYLNHPHFHTPAYVAAPSSSHTLARHSQPMTSISTQEPSYTPIELP
GLLERRFQTHLKTESIGWVFNDDVCFEWSKLLALFENLSAGTFTHQSNIIATPIKRAKGIFRVGHTARMLFQLVHNTLTR
ELIAYRKDSRLELLLDISADFDYEAFEKALLDCIQRPS
>Mature_357_residues
TSKTALNIISGQLGAGKTTLLQQLLRQRPTHETWVLLVNEFGAVGIDGPILSSQNDHTLVKQLPGGCICCTAQGELEAAV
LDIIQTQQPDRILIEPTGLGEPESLVDLFKQAKLQSLCEVHSLFSVLDMAHTQLEELQTLSILQSMLTMADVIVLNKVDL
VSPEQIRLFKDYIDTLYPPKKAVIVTEQADVSSSYLNHPHFHTPAYVAAPSSSHTLARHSQPMTSISTQEPSYTPIELPG
LLERRFQTHLKTESIGWVFNDDVCFEWSKLLALFENLSAGTFTHQSNIIATPIKRAKGIFRVGHTARMLFQLVHNTLTRE
LIAYRKDSRLELLLDISADFDYEAFEKALLDCIQRPS

Specific function: Unknown

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=187, Percent_Identity=28.8770053475936, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI126722884, Length=187, Percent_Identity=28.8770053475936, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI223941779, Length=187, Percent_Identity=28.8770053475936, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI148727351, Length=187, Percent_Identity=28.3422459893048, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI146231952, Length=181, Percent_Identity=28.7292817679558, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1788499, Length=355, Percent_Identity=27.3239436619718, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI87082430, Length=166, Percent_Identity=33.7349397590361, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324356, Length=192, Percent_Identity=28.125, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 39956; Mature: 39825

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSKTALNIISGQLGAGKTTLLQQLLRQRPTHETWVLLVNEFGAVGIDGPILSSQNDHTL
CCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHH
VKQLPGGCICCTAQGELEAAVLDIIQTQQPDRILIEPTGLGEPESLVDLFKQAKLQSLCE
HHHCCCCEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHH
VHSLFSVLDMAHTQLEELQTLSILQSMLTMADVIVLNKVDLVSPEQIRLFKDYIDTLYPP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
KKAVIVTEQADVSSSYLNHPHFHTPAYVAAPSSSHTLARHSQPMTSISTQEPSYTPIELP
CCEEEEEECCCCHHHHCCCCCCCCCCEEECCCCCCHHHHCCCCCCCCCCCCCCCCCCCCC
GLLERRFQTHLKTESIGWVFNDDVCFEWSKLLALFENLSAGTFTHQSNIIATPIKRAKGI
HHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCEECCCCEEECCHHHHCCH
FRVGHTARMLFQLVHNTLTRELIAYRKDSRLELLLDISADFDYEAFEKALLDCIQRPS
HHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TSKTALNIISGQLGAGKTTLLQQLLRQRPTHETWVLLVNEFGAVGIDGPILSSQNDHTL
CCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHH
VKQLPGGCICCTAQGELEAAVLDIIQTQQPDRILIEPTGLGEPESLVDLFKQAKLQSLCE
HHHCCCCEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHH
VHSLFSVLDMAHTQLEELQTLSILQSMLTMADVIVLNKVDLVSPEQIRLFKDYIDTLYPP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
KKAVIVTEQADVSSSYLNHPHFHTPAYVAAPSSSHTLARHSQPMTSISTQEPSYTPIELP
CCEEEEEECCCCHHHHCCCCCCCCCCEEECCCCCCHHHHCCCCCCCCCCCCCCCCCCCCC
GLLERRFQTHLKTESIGWVFNDDVCFEWSKLLALFENLSAGTFTHQSNIIATPIKRAKGI
HHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCEECCCCEEECCHHHHCCH
FRVGHTARMLFQLVHNTLTRELIAYRKDSRLELLLDISADFDYEAFEKALLDCIQRPS
HHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]