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The map label for this gene is mcpA [H]

Identifier: 78484706

GI number: 78484706

Start: 409051

End: 410856

Strand: Reverse

Name: mcpA [H]

Synonym: Tcr_0361

Alternate gene names: 78484706

Gene position: 410856-409051 (Counterclockwise)

Preceding gene: 78484707

Following gene: 78484698

Centisome position: 16.92

GC content: 43.52

Gene sequence:

>1806_bases
ATGAAAAAGCCAACGCTTTGGAGCCGAACCAAAATCTCGACCTTAAGTAATTTATTACTCATTATGATGGCGGGTGCGGG
CATTTTTTTTACCTCTGCTTTTAGCTTACTTCACCATGAAATCTTTTTGGTTCAACAAGACTGGCAAACGTTACACCCCT
TGTTATTAAACAGTTCAGCACAATCAACCTCTTCTGAAGTCGTTCGGCTTTCACACCACCTGACAGAAGGTTTAGCTTGG
ATGAGCCAACTCACGCTTATTTTTATTATTGCGGTTCTGATTGCGGTGGGTGCTTTTTTTATTTTGATGTACAACACCCT
GATGAATAAAATTGTACGGCCGCTGAGAACCTTGGAAAAAGGGATTTTAGAAATTACCTCGTCCAATGATTTTTCAAAAA
CCATTTCAATCAAATACCAGGATGAAGTTGGGCAGGTCTCACAAAGTTTTAATCAACTGTCGCATAACCTAAAAAGTATT
TTTGACCAAATTAATGATCGGCTGGCTGAAGTGGCTGATGGTAAATTTAATATTCGGTGTGATGTTGAAGTATATGGAGA
TTTAGAGGTTCTTAAAAACAATGTCAATGCATCGATTGGCAGCATTGAACTGACAATGAACTCTTTAGAATCGATCTCAC
AAGCCATTGCACAAGGAGATTTTTCTATTCGAATGGATCAAAATGTCAAAGGCAGCCTGAGAAAAAATGTCGATTTTGCA
ATGCAACAGATGGATCAAATCATCGACCAAATCAACCAGGTGATGCGCAAGGTCAACCACGCCGACTACAGCCAACGCGT
GAACATCGAAACACAAGGACGATTAACGGAACTGAAAACATTCATTAACCAAACCGTGGATACCGTTTCAATCAGCATTC
AGGCACTTAACCAAGCGGTAGACTCTCTTCACCAAGGCAATCTAACGCATCAAATTGAAACCTCGTTTAAAGGTGAACTT
AACCTGCTTAAAGAAAACCTAAACGGCACCACTTCGTATCTGAATGATACCATCATTCAGGTGATGGACGGCTCAACAGA
CGTCAACGCTGGCATTGAACAGATTGCGCAAGGCAATCAAGACCTGTCTCACCGAACACAAGGGCAAGCCGCCTCTTTAG
AAGAAATTGCAGCTGCAGTGGAACAAATGACATCGGCCATCACACAAACGGCCGACAATGGACAAAAAGCACAGACGTTC
AGTGCAGACACACTCGCATTAACGGATAAAGCCCATCATGTCATGGGTGAATCGATCGACTCAATGGCTAAGATTAAAGC
CGCCAGCGAACGCATCAGTACGTTCATTGAATTGATAGACAGCATTGCTTTCCAAACCAATCTTCTGGCTCTAAATGCCG
CGGTTGAAGCGGCCAGAGCAGGTGAGCAAGGAAGAGGCTTTGCTGTTGTAGCAGGCGAAGTTCGAAGCCTTGCTTCCAAG
TCCTCAGGTGCTTCAACTGAAATTCGAACGTTGATTGAACAAGTCGTTACCCAGGTGCAGCAAGGGTCAAGTAAACTCGA
TGAAACCAATTCCGAATTTGAACGCGTAACGCAAGGCATTCAGTCGGTTAATGATTTAATCACCGAGATTTCGCACAGCG
CGCAGGAACAAGCGAAAGGCCTGTCCCAAATCAACCAAGCGATTTCCGAACTTGATCAGGGCGTTCAACAAAACGCCGCA
TTGGTTGAACAAACTTCAGACAGTGCTCAAAATTTAACGGAATTGTCCCAGTCTCTCATGAGGTCGGTTTCACAATTCAA
AACCAGTGCACACGCTGCCTTGCCAAAGAAACTTATCGGTCAATGA

Upstream 100 bases:

>100_bases
GCCGAATAAAATCTTTTGATATAAAAGGCTCTAAAAATCATTAGAATGACTTCCTCAAGTAAATATAAATAATAATTTTT
TGCACTTAGGAACTTTTTGA

Downstream 100 bases:

>100_bases
CAAGTCAGGCTATTTAAACCATGCCGGCTGGGTGGCCGACTTTTCAAAGGTCGCCGAAATCATCACCTGAACGCGCCTGT
TTTTGGCTTTGCCCTCACGG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 601; Mature: 601

Protein sequence:

>601_residues
MKKPTLWSRTKISTLSNLLLIMMAGAGIFFTSAFSLLHHEIFLVQQDWQTLHPLLLNSSAQSTSSEVVRLSHHLTEGLAW
MSQLTLIFIIAVLIAVGAFFILMYNTLMNKIVRPLRTLEKGILEITSSNDFSKTISIKYQDEVGQVSQSFNQLSHNLKSI
FDQINDRLAEVADGKFNIRCDVEVYGDLEVLKNNVNASIGSIELTMNSLESISQAIAQGDFSIRMDQNVKGSLRKNVDFA
MQQMDQIIDQINQVMRKVNHADYSQRVNIETQGRLTELKTFINQTVDTVSISIQALNQAVDSLHQGNLTHQIETSFKGEL
NLLKENLNGTTSYLNDTIIQVMDGSTDVNAGIEQIAQGNQDLSHRTQGQAASLEEIAAAVEQMTSAITQTADNGQKAQTF
SADTLALTDKAHHVMGESIDSMAKIKAASERISTFIELIDSIAFQTNLLALNAAVEAARAGEQGRGFAVVAGEVRSLASK
SSGASTEIRTLIEQVVTQVQQGSSKLDETNSEFERVTQGIQSVNDLITEISHSAQEQAKGLSQINQAISELDQGVQQNAA
LVEQTSDSAQNLTELSQSLMRSVSQFKTSAHAALPKKLIGQ

Sequences:

>Translated_601_residues
MKKPTLWSRTKISTLSNLLLIMMAGAGIFFTSAFSLLHHEIFLVQQDWQTLHPLLLNSSAQSTSSEVVRLSHHLTEGLAW
MSQLTLIFIIAVLIAVGAFFILMYNTLMNKIVRPLRTLEKGILEITSSNDFSKTISIKYQDEVGQVSQSFNQLSHNLKSI
FDQINDRLAEVADGKFNIRCDVEVYGDLEVLKNNVNASIGSIELTMNSLESISQAIAQGDFSIRMDQNVKGSLRKNVDFA
MQQMDQIIDQINQVMRKVNHADYSQRVNIETQGRLTELKTFINQTVDTVSISIQALNQAVDSLHQGNLTHQIETSFKGEL
NLLKENLNGTTSYLNDTIIQVMDGSTDVNAGIEQIAQGNQDLSHRTQGQAASLEEIAAAVEQMTSAITQTADNGQKAQTF
SADTLALTDKAHHVMGESIDSMAKIKAASERISTFIELIDSIAFQTNLLALNAAVEAARAGEQGRGFAVVAGEVRSLASK
SSGASTEIRTLIEQVVTQVQQGSSKLDETNSEFERVTQGIQSVNDLITEISHSAQEQAKGLSQINQAISELDQGVQQNAA
LVEQTSDSAQNLTELSQSLMRSVSQFKTSAHAALPKKLIGQ
>Mature_601_residues
MKKPTLWSRTKISTLSNLLLIMMAGAGIFFTSAFSLLHHEIFLVQQDWQTLHPLLLNSSAQSTSSEVVRLSHHLTEGLAW
MSQLTLIFIIAVLIAVGAFFILMYNTLMNKIVRPLRTLEKGILEITSSNDFSKTISIKYQDEVGQVSQSFNQLSHNLKSI
FDQINDRLAEVADGKFNIRCDVEVYGDLEVLKNNVNASIGSIELTMNSLESISQAIAQGDFSIRMDQNVKGSLRKNVDFA
MQQMDQIIDQINQVMRKVNHADYSQRVNIETQGRLTELKTFINQTVDTVSISIQALNQAVDSLHQGNLTHQIETSFKGEL
NLLKENLNGTTSYLNDTIIQVMDGSTDVNAGIEQIAQGNQDLSHRTQGQAASLEEIAAAVEQMTSAITQTADNGQKAQTF
SADTLALTDKAHHVMGESIDSMAKIKAASERISTFIELIDSIAFQTNLLALNAAVEAARAGEQGRGFAVVAGEVRSLASK
SSGASTEIRTLIEQVVTQVQQGSSKLDETNSEFERVTQGIQSVNDLITEISHSAQEQAKGLSQINQAISELDQGVQQNAA
LVEQTSDSAQNLTELSQSLMRSVSQFKTSAHAALPKKLIGQ

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=292, Percent_Identity=42.8082191780822, Blast_Score=212, Evalue=7e-56,
Organism=Escherichia coli, GI1788195, Length=288, Percent_Identity=42.0138888888889, Blast_Score=208, Evalue=8e-55,
Organism=Escherichia coli, GI1787690, Length=308, Percent_Identity=39.2857142857143, Blast_Score=203, Evalue=3e-53,
Organism=Escherichia coli, GI2367378, Length=392, Percent_Identity=34.4387755102041, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI1789453, Length=254, Percent_Identity=40.5511811023622, Blast_Score=160, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 65818; Mature: 65818

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKPTLWSRTKISTLSNLLLIMMAGAGIFFTSAFSLLHHEIFLVQQDWQTLHPLLLNSSA
CCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QSTSSEVVRLSHHLTEGLAWMSQLTLIFIIAVLIAVGAFFILMYNTLMNKIVRPLRTLEK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GILEITSSNDFSKTISIKYQDEVGQVSQSFNQLSHNLKSIFDQINDRLAEVADGKFNIRC
HHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
DVEVYGDLEVLKNNVNASIGSIELTMNSLESISQAIAQGDFSIRMDQNVKGSLRKNVDFA
EEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHH
MQQMDQIIDQINQVMRKVNHADYSQRVNIETQGRLTELKTFINQTVDTVSISIQALNQAV
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSLHQGNLTHQIETSFKGELNLLKENLNGTTSYLNDTIIQVMDGSTDVNAGIEQIAQGNQ
HHHHCCCCCHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
DLSHRTQGQAASLEEIAAAVEQMTSAITQTADNGQKAQTFSADTLALTDKAHHVMGESID
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
SMAKIKAASERISTFIELIDSIAFQTNLLALNAAVEAARAGEQGRGFAVVAGEVRSLASK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHC
SSGASTEIRTLIEQVVTQVQQGSSKLDETNSEFERVTQGIQSVNDLITEISHSAQEQAKG
CCCCHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSQINQAISELDQGVQQNAALVEQTSDSAQNLTELSQSLMRSVSQFKTSAHAALPKKLIG
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHC
Q
C
>Mature Secondary Structure
MKKPTLWSRTKISTLSNLLLIMMAGAGIFFTSAFSLLHHEIFLVQQDWQTLHPLLLNSSA
CCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QSTSSEVVRLSHHLTEGLAWMSQLTLIFIIAVLIAVGAFFILMYNTLMNKIVRPLRTLEK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GILEITSSNDFSKTISIKYQDEVGQVSQSFNQLSHNLKSIFDQINDRLAEVADGKFNIRC
HHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
DVEVYGDLEVLKNNVNASIGSIELTMNSLESISQAIAQGDFSIRMDQNVKGSLRKNVDFA
EEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHH
MQQMDQIIDQINQVMRKVNHADYSQRVNIETQGRLTELKTFINQTVDTVSISIQALNQAV
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSLHQGNLTHQIETSFKGELNLLKENLNGTTSYLNDTIIQVMDGSTDVNAGIEQIAQGNQ
HHHHCCCCCHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
DLSHRTQGQAASLEEIAAAVEQMTSAITQTADNGQKAQTFSADTLALTDKAHHVMGESID
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
SMAKIKAASERISTFIELIDSIAFQTNLLALNAAVEAARAGEQGRGFAVVAGEVRSLASK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHC
SSGASTEIRTLIEQVVTQVQQGSSKLDETNSEFERVTQGIQSVNDLITEISHSAQEQAKG
CCCCHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSQINQAISELDQGVQQNAALVEQTSDSAQNLTELSQSLMRSVSQFKTSAHAALPKKLIG
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]