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The map label for this gene is cmoA

Identifier: 78484425

GI number: 78484425

Start: 100812

End: 101567

Strand: Reverse

Name: cmoA

Synonym: Tcr_0079

Alternate gene names: 78484425

Gene position: 101567-100812 (Counterclockwise)

Preceding gene: 78484426

Following gene: 78484424

Centisome position: 4.18

GC content: 46.16

Gene sequence:

>756_bases
ATGTTGATCTCGCGTTACACAGGAATTCCCATTTTGAAAGACACTCTGTATGCACACCCTTATGAAGCGGTTGGCGAATT
TCAATTCGACGACTCGGTCGTCGCAGTCTTTCCGGACATGATTCAACGCTCCGTACCCGGTTATCAAACGATTTTGACGG
GCATCGGTGAACTGACTGCAAAATATGCACAACCGAACAGCCAACTGTACGACTTGGGCTGTTCTTTAGGCGCCGCCACC
TTAACCATGCGTCGCAAAGCGCCTCAAGGAAGTCAGATCATTGCCGTCGACACCTCACAACCGATGATCGAGCGCGCCAA
AGAGCATATCGAGGGGTTTCATTCGGATATTCCGGTGCGTTTACTGTGTGACGACATGACCCAGATTCCAATTGAAAATG
CTTCTGTCGTCGTCATTAATTTTACCTTGCAGTTTATAGAACCTTCAGCACGACAAGTATTGCTCGACAAAATTTATCAA
GGCTTGAAGCCTGGCGGCATTTTGATTTTATCGGAAAAAATTCATTTTGAATCGGCCGAACTTCAGGAGGCCATTGAGCA
TTTACAACTGCAATTCAAACGTGCTAATGGGTACTCAGAGCTTGAAATCAGCCAAAAACGCGCGTCACTTGAAAACGTCT
TAATCAGTGACTCGGAAGCGACGCATCTCAACCGGTTGCAACAGTCCGGATTTAAAGCCGCTAACATTTGGTTTCAAGCC
TATAATTTCGCTTCCTTTCTGGCCATTAAAGCTTAA

Upstream 100 bases:

>100_bases
TGAGGTTTCCTCAGAAAGCATGATTATCCCGAACAGATATTTTATAATACCTTTCATATTGACCCTTTAAAGCCATGCTG
GCACTTTGTGCTCAGTGATT

Downstream 100 bases:

>100_bases
AACGATACACTCATAAGGTTCCATGTGAAACATTATCACCAACACTATTCTTCTTTTTGGCCCAAACTGGAAGAAGCTCG
CCTCGGACACTGGCAAAATG

Product: methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MLISRYTGIPILKDTLYAHPYEAVGEFQFDDSVVAVFPDMIQRSVPGYQTILTGIGELTAKYAQPNSQLYDLGCSLGAAT
LTMRRKAPQGSQIIAVDTSQPMIERAKEHIEGFHSDIPVRLLCDDMTQIPIENASVVVINFTLQFIEPSARQVLLDKIYQ
GLKPGGILILSEKIHFESAELQEAIEHLQLQFKRANGYSELEISQKRASLENVLISDSEATHLNRLQQSGFKAANIWFQA
YNFASFLAIKA

Sequences:

>Translated_251_residues
MLISRYTGIPILKDTLYAHPYEAVGEFQFDDSVVAVFPDMIQRSVPGYQTILTGIGELTAKYAQPNSQLYDLGCSLGAAT
LTMRRKAPQGSQIIAVDTSQPMIERAKEHIEGFHSDIPVRLLCDDMTQIPIENASVVVINFTLQFIEPSARQVLLDKIYQ
GLKPGGILILSEKIHFESAELQEAIEHLQLQFKRANGYSELEISQKRASLENVLISDSEATHLNRLQQSGFKAANIWFQA
YNFASFLAIKA
>Mature_251_residues
MLISRYTGIPILKDTLYAHPYEAVGEFQFDDSVVAVFPDMIQRSVPGYQTILTGIGELTAKYAQPNSQLYDLGCSLGAAT
LTMRRKAPQGSQIIAVDTSQPMIERAKEHIEGFHSDIPVRLLCDDMTQIPIENASVVVINFTLQFIEPSARQVLLDKIYQ
GLKPGGILILSEKIHFESAELQEAIEHLQLQFKRANGYSELEISQKRASLENVLISDSEATHLNRLQQSGFKAANIWFQA
YNFASFLAIKA

Specific function: Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U)

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. CmoA family

Homologues:

Organism=Escherichia coli, GI1788177, Length=240, Percent_Identity=55.4166666666667, Blast_Score=285, Evalue=3e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CMOA_THICR (Q31JJ7)

Other databases:

- EMBL:   CP000109
- RefSeq:   YP_390350.1
- ProteinModelPortal:   Q31JJ7
- SMR:   Q31JJ7
- STRING:   Q31JJ7
- GeneID:   3761464
- GenomeReviews:   CP000109_GR
- KEGG:   tcx:Tcr_0079
- NMPDR:   fig|317025.3.peg.232
- eggNOG:   COG0500
- HOGENOM:   HBG296860
- OMA:   YSELEVS
- PhylomeDB:   Q31JJ7
- BioCyc:   TCRU317025:TCR_0079-MONOMER
- HAMAP:   MF_01589
- InterPro:   IPR013216
- InterPro:   IPR005271
- PIRSF:   PIRSF006325
- TIGRFAMs:   TIGR00740

Pfam domain/function: PF08241 Methyltransf_11

EC number: NA

Molecular weight: Translated: 28020; Mature: 28020

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: BINDING 48-48 BINDING 97-97 BINDING 140-140 BINDING 207-207

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLISRYTGIPILKDTLYAHPYEAVGEFQFDDSVVAVFPDMIQRSVPGYQTILTGIGELTA
CEECCCCCCCHHHHHHHCCCHHHHCCCCCCCCHHHCCHHHHHHCCCCHHHHHHHHHHHHH
KYAQPNSQLYDLGCSLGAATLTMRRKAPQGSQIIAVDTSQPMIERAKEHIEGFHSDIPVR
HHCCCCCHHHHHCCCCCHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCEE
LLCDDMTQIPIENASVVVINFTLQFIEPSARQVLLDKIYQGLKPGGILILSEKIHFESAE
EEECCHHHCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHH
LQEAIEHLQLQFKRANGYSELEISQKRASLENVLISDSEATHLNRLQQSGFKAANIWFQA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHCCCCCHHHHHHH
YNFASFLAIKA
HCHHHEEEECC
>Mature Secondary Structure
MLISRYTGIPILKDTLYAHPYEAVGEFQFDDSVVAVFPDMIQRSVPGYQTILTGIGELTA
CEECCCCCCCHHHHHHHCCCHHHHCCCCCCCCHHHCCHHHHHHCCCCHHHHHHHHHHHHH
KYAQPNSQLYDLGCSLGAATLTMRRKAPQGSQIIAVDTSQPMIERAKEHIEGFHSDIPVR
HHCCCCCHHHHHCCCCCHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCEE
LLCDDMTQIPIENASVVVINFTLQFIEPSARQVLLDKIYQGLKPGGILILSEKIHFESAE
EEECCHHHCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHH
LQEAIEHLQLQFKRANGYSELEISQKRASLENVLISDSEATHLNRLQQSGFKAANIWFQA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHCCCCCHHHHHHH
YNFASFLAIKA
HCHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA