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The map label for this gene is selA [H]

Identifier: 78358099

GI number: 78358099

Start: 3050093

End: 3051544

Strand: Direct

Name: selA [H]

Synonym: Dde_3059

Alternate gene names: 78358099

Gene position: 3050093-3051544 (Clockwise)

Preceding gene: 78358098

Following gene: 78358100

Centisome position: 81.77

GC content: 62.19

Gene sequence:

>1452_bases
GTGAACCAGCTTTTCCGCTCTCTGCCCTCTGTTGATGCCGTGCTGCACGCGCTGGCGGCCCGGCCGCAGGAAGCCGCTTC
CGGTTCCCGCAGCCGGAAAGATACCCCACCCACCGGCAATGACGCAGCCAGCATGCCGCGCGCCATGCTGCGCGAGCATA
TCAACGCATTTCTGGATATCTGCCGCGAAGAAATCCGCGCCGGAGTGCACTCCAGTCCCGAAGCGCTTTCGCTGGATGCG
CTGCTGCCGCGCCTGACCGCATATGTCGCAGCCAAAAGCAGGCCGCGTTTCAGGCGGGTTCTCAACGGCACGGGCGTGGT
GGTGCACACCAATCTGGGCCGTTCGCTGCTGGCGGCAGAAGCCACACGCGCCGTCAGTCAGGCATGCGCCCACTACTCCA
ACCTTGAGTTCGACCTTGCCACCGGTGAACGCGGCAGCCGCTACAGCCATGTGGAAGAAATACTGAAAAGCGTGACAGGC
GCAGAAGCCGGTCTGGTGGTCAACAACAATGCCGCCGCCGTACTGCTGGTGCTGGACACTCTGTGCAAAGGCAGAGAGGT
CATCGTCTCACGCGGGCAGCTGGTAGAAATAGGCGGCAGTTTCCGCATTCCCGATGTGATGACCCGCAGCGGTGCCATAC
TGCGCGAGGTGGGCGCCACCAACCGCACGCATCTCAAAGACTATGCCGGGGCCATCAACGAAAACACGGCGGCGCTGCTC
AAGGTGCATACCTCCAATTACCGCATCACGGGATTCCACAAAGAGGTGCCGCTGGAAGAACTGTGCAGTCTGGGCAGACA
GCACCGGCTTCCGGTCATTGAAGATCTGGGCAGCGGTGTGTTTTATGATTTTTCCGGCCTGGGCATGGGGCACGAACCCA
CAGTGCAACAGGTGGTGGCTGACGGTGCCGACGTGGTCACTTTTTCGGGAGACAAAGTGCTGGGCGGCCCGCAGGCAGGC
ATTATAGTGGGGCGGCGTGAAATAATAGAACGCATCAAGAAAAACCCCATGAACCGCGCCCTGCGCATTGATAAAATGAC
ACTCGCCGCGCTGGAAGCCACTTTGCGGCTGTATACAGACATGGACCGCGCCAGACGCGAAATTCCCACGCTTGCCATGA
TTCTGGCCACCCCGGACGAACTGGCCCGCCGCGCACGACGGCTTGCCGCCCGCCTGCGCAGAACACTGGAAGACCGCGCC
ACGGTAACCCTGCGCAAGGGCGCTTCACGCGTGGGCGGGGGCTCTTTTCCCGAACGCGACCTGCCCACCACACTGGCCTG
CGTGCATCCGGCATCCGTTTCCGCCACCGAACTGAAAAACCGCCTGCTGGACACCGACCCGCCGCTGGCCGGCATGCTGC
TGGAAGACGCTTTCTGCCTTGACCCCAGAACCCTGACCGACGAAGAATTCAAACTGGCAGCGGGCGCGCTGGCACAGGCC
CTGAACGTCTGA

Upstream 100 bases:

>100_bases
ACGCGGCGACCGGCTGAACCCGGACCATGCTGCGCCGTACTCCGGTAGCACAAGGCATCGCCCACCGTCGTCATGCCACC
AATCAGCCAAGGAAGCGCCT

Downstream 100 bases:

>100_bases
ATATCCCCGACGGCCATCAAACGGAGAACTGCATGCAACAGGGAGAATTCAAAAATCTTGCCCGCAAGCGCATTCTGGTA
ACCGGCGGGGCGGGCTTCAT

Product: selenocysteine synthase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase [H]

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MNQLFRSLPSVDAVLHALAARPQEAASGSRSRKDTPPTGNDAASMPRAMLREHINAFLDICREEIRAGVHSSPEALSLDA
LLPRLTAYVAAKSRPRFRRVLNGTGVVVHTNLGRSLLAAEATRAVSQACAHYSNLEFDLATGERGSRYSHVEEILKSVTG
AEAGLVVNNNAAAVLLVLDTLCKGREVIVSRGQLVEIGGSFRIPDVMTRSGAILREVGATNRTHLKDYAGAINENTAALL
KVHTSNYRITGFHKEVPLEELCSLGRQHRLPVIEDLGSGVFYDFSGLGMGHEPTVQQVVADGADVVTFSGDKVLGGPQAG
IIVGRREIIERIKKNPMNRALRIDKMTLAALEATLRLYTDMDRARREIPTLAMILATPDELARRARRLAARLRRTLEDRA
TVTLRKGASRVGGGSFPERDLPTTLACVHPASVSATELKNRLLDTDPPLAGMLLEDAFCLDPRTLTDEEFKLAAGALAQA
LNV

Sequences:

>Translated_483_residues
MNQLFRSLPSVDAVLHALAARPQEAASGSRSRKDTPPTGNDAASMPRAMLREHINAFLDICREEIRAGVHSSPEALSLDA
LLPRLTAYVAAKSRPRFRRVLNGTGVVVHTNLGRSLLAAEATRAVSQACAHYSNLEFDLATGERGSRYSHVEEILKSVTG
AEAGLVVNNNAAAVLLVLDTLCKGREVIVSRGQLVEIGGSFRIPDVMTRSGAILREVGATNRTHLKDYAGAINENTAALL
KVHTSNYRITGFHKEVPLEELCSLGRQHRLPVIEDLGSGVFYDFSGLGMGHEPTVQQVVADGADVVTFSGDKVLGGPQAG
IIVGRREIIERIKKNPMNRALRIDKMTLAALEATLRLYTDMDRARREIPTLAMILATPDELARRARRLAARLRRTLEDRA
TVTLRKGASRVGGGSFPERDLPTTLACVHPASVSATELKNRLLDTDPPLAGMLLEDAFCLDPRTLTDEEFKLAAGALAQA
LNV
>Mature_483_residues
MNQLFRSLPSVDAVLHALAARPQEAASGSRSRKDTPPTGNDAASMPRAMLREHINAFLDICREEIRAGVHSSPEALSLDA
LLPRLTAYVAAKSRPRFRRVLNGTGVVVHTNLGRSLLAAEATRAVSQACAHYSNLEFDLATGERGSRYSHVEEILKSVTG
AEAGLVVNNNAAAVLLVLDTLCKGREVIVSRGQLVEIGGSFRIPDVMTRSGAILREVGATNRTHLKDYAGAINENTAALL
KVHTSNYRITGFHKEVPLEELCSLGRQHRLPVIEDLGSGVFYDFSGLGMGHEPTVQQVVADGADVVTFSGDKVLGGPQAG
IIVGRREIIERIKKNPMNRALRIDKMTLAALEATLRLYTDMDRARREIPTLAMILATPDELARRARRLAARLRRTLEDRA
TVTLRKGASRVGGGSFPERDLPTTLACVHPASVSATELKNRLLDTDPPLAGMLLEDAFCLDPRTLTDEEFKLAAGALAQA
LNV

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis [H]

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family [H]

Homologues:

Organism=Escherichia coli, GI2367248, Length=426, Percent_Identity=45.5399061032864, Blast_Score=304, Evalue=8e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534 [H]

Pfam domain/function: PF03841 SelA [H]

EC number: =2.9.1.1 [H]

Molecular weight: Translated: 52304; Mature: 52304

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQLFRSLPSVDAVLHALAARPQEAASGSRSRKDTPPTGNDAASMPRAMLREHINAFLDI
CCHHHHHCCHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
CREEIRAGVHSSPEALSLDALLPRLTAYVAAKSRPRFRRVLNGTGVVVHTNLGRSLLAAE
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEECCCCHHHHHHH
ATRAVSQACAHYSNLEFDLATGERGSRYSHVEEILKSVTGAEAGLVVNNNAAAVLLVLDT
HHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHH
LCKGREVIVSRGQLVEIGGSFRIPDVMTRSGAILREVGATNRTHLKDYAGAINENTAALL
HHCCCHHHHCCCCEEEECCCCCCCHHHHHCCHHHHHHCCCCCHHHHHHHCCCCCCCEEEE
KVHTSNYRITGFHKEVPLEELCSLGRQHRLPVIEDLGSGVFYDFSGLGMGHEPTVQQVVA
EEECCCEEEEECCCCCCHHHHHHCHHHCCCCHHHHCCCCCEEECCCCCCCCCHHHHHHHH
DGADVVTFSGDKVLGGPQAGIIVGRREIIERIKKNPMNRALRIDKMTLAALEATLRLYTD
CCCCEEEECCCEEECCCCCCEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
MDRARREIPTLAMILATPDELARRARRLAARLRRTLEDRATVTLRKGASRVGGGSFPERD
HHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCC
LPTTLACVHPASVSATELKNRLLDTDPPLAGMLLEDAFCLDPRTLTDEEFKLAAGALAQA
CCCEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
LNV
HCC
>Mature Secondary Structure
MNQLFRSLPSVDAVLHALAARPQEAASGSRSRKDTPPTGNDAASMPRAMLREHINAFLDI
CCHHHHHCCHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
CREEIRAGVHSSPEALSLDALLPRLTAYVAAKSRPRFRRVLNGTGVVVHTNLGRSLLAAE
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEECCCCHHHHHHH
ATRAVSQACAHYSNLEFDLATGERGSRYSHVEEILKSVTGAEAGLVVNNNAAAVLLVLDT
HHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHH
LCKGREVIVSRGQLVEIGGSFRIPDVMTRSGAILREVGATNRTHLKDYAGAINENTAALL
HHCCCHHHHCCCCEEEECCCCCCCHHHHHCCHHHHHHCCCCCHHHHHHHCCCCCCCEEEE
KVHTSNYRITGFHKEVPLEELCSLGRQHRLPVIEDLGSGVFYDFSGLGMGHEPTVQQVVA
EEECCCEEEEECCCCCCHHHHHHCHHHCCCCHHHHCCCCCEEECCCCCCCCCHHHHHHHH
DGADVVTFSGDKVLGGPQAGIIVGRREIIERIKKNPMNRALRIDKMTLAALEATLRLYTD
CCCCEEEECCCEEECCCCCCEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
MDRARREIPTLAMILATPDELARRARRLAARLRRTLEDRATVTLRKGASRVGGGSFPERD
HHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCC
LPTTLACVHPASVSATELKNRLLDTDPPLAGMLLEDAFCLDPRTLTDEEFKLAAGALAQA
CCCEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
LNV
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA