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The map label for this gene is yebQ [H]

Identifier: 78357771

GI number: 78357771

Start: 2730997

End: 2732406

Strand: Direct

Name: yebQ [H]

Synonym: Dde_2729

Alternate gene names: 78357771

Gene position: 2730997-2732406 (Clockwise)

Preceding gene: 78357756

Following gene: 78357772

Centisome position: 73.21

GC content: 63.33

Gene sequence:

>1410_bases
ATGAAACAATTTCTTTCCGGCCCCCGCGCGGGCATATCGTCAGGACTGCCGGTGCTGTACACCGTGGCCGCCACCCAGTT
CATCATGCCGTTCATGTTTTCGGGCGTGGCCGTCACCCTGCCGGTCATGGGGCAGGAGTTCGGGGCGGGCGGCACGGCGC
TGGGGCTTGTGGAATCCATATATCTTGCCGCCACGGGCGCTCTGCTGCTGCCTTTGGGCAGGCTGGCCGACATGGCGGGG
CACGCCCCGCTTTTCCGCTCGGGCGTGCTGCTGTACGCCGTTTCCACACTGCTGCTCAGTTTTACGCAGGACATGACAAC
CTTCATTCTGCTGCGTCTTGTGCAGGGCACCGGCGCTGCCATGACCATGGCGTCCAACATGGCCCTGCTGACCAAAGCCA
TTCCGCGCAGCGAACGCGGCAGGGCCATGGGCATAGCGGTGGCCAGCGTGTATCTGGGGCTTTCTGCAGGGCCGTTTCTG
GGAGGCGCCATCGCCACGCATCTGGGCTGGCGCTGGCTGTACATACTGGGAACACCGCCGCTGGCGCTGGCCTATCTGCT
GGCACGCCGCAACCTTAAAGAACGCTGGCAGCCCGTAACGGAACCATTTGACTGGGCCGGGGCCGCGCTTTCGGTCTGCG
CCGTGGGTCTGGCTGTTTTCGGCGGGCCCAGACTGGCGGCCGGCCCCGGCGGCATACTGGCACTGGCCGGCAGCATGGTC
TGCGGCGCACTTTTTCTGGTGGTAGAATCACGCACAGCCAATCCGCTGCTCGACCTTGCCCTGCTGCGGCGCAACAAAAC
GTTCAGCTTTGCCACGGCTGCCCAGTTCATCAATTATGCCGCAACATTCGGCATCACATTTCTGTTCAGTCTGTATCTGC
AGAACGCCCGCGGCATGACTGCGCAGGAGACCGGCACCGTATTGCTGGTACAGCCTCTGGTGCAGACGCTGCTTTCGCCG
TTGTGCGGACGGCTGGCAGACAGCATGCCCGCGCACCGCATAGCCACGGCGGGCATGGCATGCTGCACCGCGGGCACCCT
GATGGCGGCCATGACCGGCGCAGACACGTCCATGGCTTTCATGCTGACCATGTTTGTGGTGCTGGGGGTGGGTTTTGCCC
TGTTTGCATCGCCCAACATGAGCATCATCATGGGCAGCGTGCAGACCGGCCGCTACGGCATAGCCTCGGCCATGGCGGCC
AGCATGCGCACGCTGGGCATGGTACTCAGCATGGTTCTGGTAACCGCCGCCATGTCGCTGCATACGGGCGATGCCGTGGT
GACCGCAGAAAACGCCGACGCCTTTATTTCGGCCATGCGCTGGTCGTTTGCCGTTTTTTCGGCACTGGGAGGCTTCGGAG
TGGCACTTTCTCTTTTCGCCTCGCTTTCGCCGGATGCCCCCCGCGAATAA

Upstream 100 bases:

>100_bases
GAAACGCGCACTTTCGGCAACCGTACGGCGCAGCGTCTGTCCGGCGCTTTTTTACGGCGCGGCCGCACTCCGCAGTTCCA
CCGCAACAGCAAATTCCAGT

Downstream 100 bases:

>100_bases
AGTCCGCTTTTCACGGGCGCTGACGCAGCTTTCTTTTTGACAGCGCCATACCCTACCGCATATGGTCACGTCTTATCGTT
TTCACCTTTTTATTTCGGAG

Product: drug resistance transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MKQFLSGPRAGISSGLPVLYTVAATQFIMPFMFSGVAVTLPVMGQEFGAGGTALGLVESIYLAATGALLLPLGRLADMAG
HAPLFRSGVLLYAVSTLLLSFTQDMTTFILLRLVQGTGAAMTMASNMALLTKAIPRSERGRAMGIAVASVYLGLSAGPFL
GGAIATHLGWRWLYILGTPPLALAYLLARRNLKERWQPVTEPFDWAGAALSVCAVGLAVFGGPRLAAGPGGILALAGSMV
CGALFLVVESRTANPLLDLALLRRNKTFSFATAAQFINYAATFGITFLFSLYLQNARGMTAQETGTVLLVQPLVQTLLSP
LCGRLADSMPAHRIATAGMACCTAGTLMAAMTGADTSMAFMLTMFVVLGVGFALFASPNMSIIMGSVQTGRYGIASAMAA
SMRTLGMVLSMVLVTAAMSLHTGDAVVTAENADAFISAMRWSFAVFSALGGFGVALSLFASLSPDAPRE

Sequences:

>Translated_469_residues
MKQFLSGPRAGISSGLPVLYTVAATQFIMPFMFSGVAVTLPVMGQEFGAGGTALGLVESIYLAATGALLLPLGRLADMAG
HAPLFRSGVLLYAVSTLLLSFTQDMTTFILLRLVQGTGAAMTMASNMALLTKAIPRSERGRAMGIAVASVYLGLSAGPFL
GGAIATHLGWRWLYILGTPPLALAYLLARRNLKERWQPVTEPFDWAGAALSVCAVGLAVFGGPRLAAGPGGILALAGSMV
CGALFLVVESRTANPLLDLALLRRNKTFSFATAAQFINYAATFGITFLFSLYLQNARGMTAQETGTVLLVQPLVQTLLSP
LCGRLADSMPAHRIATAGMACCTAGTLMAAMTGADTSMAFMLTMFVVLGVGFALFASPNMSIIMGSVQTGRYGIASAMAA
SMRTLGMVLSMVLVTAAMSLHTGDAVVTAENADAFISAMRWSFAVFSALGGFGVALSLFASLSPDAPRE
>Mature_469_residues
MKQFLSGPRAGISSGLPVLYTVAATQFIMPFMFSGVAVTLPVMGQEFGAGGTALGLVESIYLAATGALLLPLGRLADMAG
HAPLFRSGVLLYAVSTLLLSFTQDMTTFILLRLVQGTGAAMTMASNMALLTKAIPRSERGRAMGIAVASVYLGLSAGPFL
GGAIATHLGWRWLYILGTPPLALAYLLARRNLKERWQPVTEPFDWAGAALSVCAVGLAVFGGPRLAAGPGGILALAGSMV
CGALFLVVESRTANPLLDLALLRRNKTFSFATAAQFINYAATFGITFLFSLYLQNARGMTAQETGTVLLVQPLVQTLLSP
LCGRLADSMPAHRIATAGMACCTAGTLMAAMTGADTSMAFMLTMFVVLGVGFALFASPNMSIIMGSVQTGRYGIASAMAA
SMRTLGMVLSMVLVTAAMSLHTGDAVVTAENADAFISAMRWSFAVFSALGGFGVALSLFASLSPDAPRE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=373, Percent_Identity=28.686327077748, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1788710, Length=386, Percent_Identity=25.3886010362694, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789042, Length=406, Percent_Identity=24.8768472906404, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790195, Length=243, Percent_Identity=27.5720164609054, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323735, Length=310, Percent_Identity=24.1935483870968, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48780; Mature: 48780

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQFLSGPRAGISSGLPVLYTVAATQFIMPFMFSGVAVTLPVMGQEFGAGGTALGLVESI
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHEEEEHHCCCCCCCCHHHHHHHHH
YLAATGALLLPLGRLADMAGHAPLFRSGVLLYAVSTLLLSFTQDMTTFILLRLVQGTGAA
HHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
MTMASNMALLTKAIPRSERGRAMGIAVASVYLGLSAGPFLGGAIATHLGWRWLYILGTPP
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEECCCH
LALAYLLARRNLKERWQPVTEPFDWAGAALSVCAVGLAVFGGPRLAAGPGGILALAGSMV
HHHHHHHHHHCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
CGALFLVVESRTANPLLDLALLRRNKTFSFATAAQFINYAATFGITFLFSLYLQNARGMT
HHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AQETGTVLLVQPLVQTLLSPLCGRLADSMPAHRIATAGMACCTAGTLMAAMTGADTSMAF
CCCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
MLTMFVVLGVGFALFASPNMSIIMGSVQTGRYGIASAMAASMRTLGMVLSMVLVTAAMSL
HHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HTGDAVVTAENADAFISAMRWSFAVFSALGGFGVALSLFASLSPDAPRE
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKQFLSGPRAGISSGLPVLYTVAATQFIMPFMFSGVAVTLPVMGQEFGAGGTALGLVESI
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHEEEEHHCCCCCCCCHHHHHHHHH
YLAATGALLLPLGRLADMAGHAPLFRSGVLLYAVSTLLLSFTQDMTTFILLRLVQGTGAA
HHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
MTMASNMALLTKAIPRSERGRAMGIAVASVYLGLSAGPFLGGAIATHLGWRWLYILGTPP
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEECCCH
LALAYLLARRNLKERWQPVTEPFDWAGAALSVCAVGLAVFGGPRLAAGPGGILALAGSMV
HHHHHHHHHHCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
CGALFLVVESRTANPLLDLALLRRNKTFSFATAAQFINYAATFGITFLFSLYLQNARGMT
HHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AQETGTVLLVQPLVQTLLSPLCGRLADSMPAHRIATAGMACCTAGTLMAAMTGADTSMAF
CCCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
MLTMFVVLGVGFALFASPNMSIIMGSVQTGRYGIASAMAASMRTLGMVLSMVLVTAAMSL
HHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HTGDAVVTAENADAFISAMRWSFAVFSALGGFGVALSLFASLSPDAPRE
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]