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The map label for this gene is ymdB [H]

Identifier: 78357166

GI number: 78357166

Start: 2173049

End: 2173600

Strand: Direct

Name: ymdB [H]

Synonym: Dde_2123

Alternate gene names: 78357166

Gene position: 2173049-2173600 (Clockwise)

Preceding gene: 78357165

Following gene: 78357167

Centisome position: 58.26

GC content: 62.14

Gene sequence:

>552_bases
ATGCAATGGTCTTCAGCAACAGGCTGTCTGGAAATACTGCAGGGCGATCTGACCCTTTTCAAAGCCGACGCCGTTGTCAA
TGCGGCCAACAGCCGTCTGGCCGGAGGCGGGGGTGTTGACGGAGCCTTACATGCAGCCGCAGGCCCCGCGCTGCTGGCTG
ACTGCTCGCGTTGGGTGGCCCGCCACGGACTACTGCCCGCAGGCAAGGCCATGGTCACCCCTGCCCACAGACTGCCGGCC
CGCCATGTCATTCATACTGTCGGCCCCGTGTGGCGCGGCGGTAAAAACAATGAAGAGACAACCCTGCGACAGGCGTACGA
ATCCTGCTTCACCCTGTGCCGCAGCAACGGTTTCGCCCATGTGGCTTTTCCGGCCATAAGCTGCGGAACATACGGGTATC
CGGCATCGCCGGCCGCCCGGGTGGCACTGGCGTGTGCCGCACAGGCTCTGGCCTGTCAGGGCGCCCCCGCAAAAATAACC
TTCGTGCTGCATACGGCACAAATGTACACAATCTGGTTGAAAGCTGCGCAAGATGCGGCGCCAGACCTGTAA

Upstream 100 bases:

>100_bases
AGGCGGAAACACTTGCCCGCACAGAGGATGACAAGGCCGAACTGGAACGGTTTGACACCCGTCATGCAGAACGTGCGGAG
TTCTGGTAGAGGGCTGCGGC

Downstream 100 bases:

>100_bases
AGCGAGAGACATATGGATCTGAAAGGAACGACTATTCTGGCGGTAAAAGATGACGAAGGTGTTTCCATGGCCGGTGACGG
ACAGGTTACGCTCGGTCAGG

Product: Appr-1-p processing

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MQWSSATGCLEILQGDLTLFKADAVVNAANSRLAGGGGVDGALHAAAGPALLADCSRWVARHGLLPAGKAMVTPAHRLPA
RHVIHTVGPVWRGGKNNEETTLRQAYESCFTLCRSNGFAHVAFPAISCGTYGYPASPAARVALACAAQALACQGAPAKIT
FVLHTAQMYTIWLKAAQDAAPDL

Sequences:

>Translated_183_residues
MQWSSATGCLEILQGDLTLFKADAVVNAANSRLAGGGGVDGALHAAAGPALLADCSRWVARHGLLPAGKAMVTPAHRLPA
RHVIHTVGPVWRGGKNNEETTLRQAYESCFTLCRSNGFAHVAFPAISCGTYGYPASPAARVALACAAQALACQGAPAKIT
FVLHTAQMYTIWLKAAQDAAPDL
>Mature_183_residues
MQWSSATGCLEILQGDLTLFKADAVVNAANSRLAGGGGVDGALHAAAGPALLADCSRWVARHGLLPAGKAMVTPAHRLPA
RHVIHTVGPVWRGGKNNEETTLRQAYESCFTLCRSNGFAHVAFPAISCGTYGYPASPAARVALACAAQALACQGAPAKIT
FVLHTAQMYTIWLKAAQDAAPDL

Specific function: Unknown

COG id: COG2110

COG function: function code R; Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Macro domain [H]

Homologues:

Organism=Homo sapiens, GI117968621, Length=176, Percent_Identity=40.9090909090909, Blast_Score=125, Evalue=2e-29,
Organism=Homo sapiens, GI13569840, Length=136, Percent_Identity=44.8529411764706, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI154813199, Length=126, Percent_Identity=42.8571428571429, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI226371718, Length=150, Percent_Identity=35.3333333333333, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI226371716, Length=150, Percent_Identity=35.3333333333333, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI226371714, Length=150, Percent_Identity=35.3333333333333, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI226371712, Length=150, Percent_Identity=35.3333333333333, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI226371710, Length=150, Percent_Identity=35.3333333333333, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI226371706, Length=150, Percent_Identity=35.3333333333333, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI20336746, Length=167, Percent_Identity=28.7425149700599, Blast_Score=78, Evalue=3e-15,
Organism=Homo sapiens, GI207450721, Length=160, Percent_Identity=27.5, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI8923143, Length=160, Percent_Identity=27.5, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1787283, Length=172, Percent_Identity=44.7674418604651, Blast_Score=152, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI17538214, Length=158, Percent_Identity=36.7088607594937, Blast_Score=96, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002589
- InterPro:   IPR022942 [H]

Pfam domain/function: PF01661 Macro [H]

EC number: NA

Molecular weight: Translated: 19021; Mature: 19021

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS51154 MACRO

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQWSSATGCLEILQGDLTLFKADAVVNAANSRLAGGGGVDGALHAAAGPALLADCSRWVA
CCCCCHHHHHHHHHCCHHEEEHHHHHHHCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHH
RHGLLPAGKAMVTPAHRLPARHVIHTVGPVWRGGKNNEETTLRQAYESCFTLCRSNGFAH
HCCCCCCCCEEECCHHHCCHHHHHHHHCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEE
VAFPAISCGTYGYPASPAARVALACAAQALACQGAPAKITFVLHTAQMYTIWLKAAQDAA
EEECEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHCC
PDL
CCC
>Mature Secondary Structure
MQWSSATGCLEILQGDLTLFKADAVVNAANSRLAGGGGVDGALHAAAGPALLADCSRWVA
CCCCCHHHHHHHHHCCHHEEEHHHHHHHCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHH
RHGLLPAGKAMVTPAHRLPARHVIHTVGPVWRGGKNNEETTLRQAYESCFTLCRSNGFAH
HCCCCCCCCEEECCHHHCCHHHHHHHHCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEE
VAFPAISCGTYGYPASPAARVALACAAQALACQGAPAKITFVLHTAQMYTIWLKAAQDAA
EEECEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHCC
PDL
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]