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The map label for this gene is hslV

Identifier: 78357167

GI number: 78357167

Start: 2173613

End: 2174155

Strand: Direct

Name: hslV

Synonym: Dde_2124

Alternate gene names: 78357167

Gene position: 2173613-2174155 (Clockwise)

Preceding gene: 78357166

Following gene: 78357168

Centisome position: 58.27

GC content: 57.09

Gene sequence:

>543_bases
ATGGATCTGAAAGGAACGACTATTCTGGCGGTAAAAGATGACGAAGGTGTTTCCATGGCCGGTGACGGACAGGTTACGCT
CGGTCAGGCCATTGTAATGAAACATGGAGCCCGCAAAGTCAGACGCATATATAAAGATAGAATCATCGCCGGATTCGCAG
GGTCAACGGCCGATGCGTTCACGTTGTTTGAACGCTTTGAAGCCAAGCTGGAAGAATTCGGCGGCAACCTGCTGCGCGCC
AGCGTTGAGATGGCGAAAGACTGGAGAAAAGACAAGTTTCTGCGGAGACTTGAGGCCATGTTGCTCGTTTCGGACGGCAC
CACCCTGCTTATGCTGAGCGGCACCGGCGACGTCATTGAACCGGACGACGGCGTGGCAGCCATCGGCAGCGGCGGCCCTT
ATGCTCTGGCCGCGGCACGGGCACTGCAACGCCACACGGCCCTGAGCGCTCAGGAAATTGTGACCAAAGCCATGGCCATT
GCGGGCGAGCTGTGTGTTTTCACCAATGACCACCTGACCGTGGAAAACGCGCGGCGGGCATAA

Upstream 100 bases:

>100_bases
CCCCGCAAAAATAACCTTCGTGCTGCATACGGCACAAATGTACACAATCTGGTTGAAAGCTGCGCAAGATGCGGCGCCAG
ACCTGTAAAGCGAGAGACAT

Downstream 100 bases:

>100_bases
ATGCTTACCGTTCCGCAACAGACCATCCGCTCGGGGTGCAAGATAAACCTGTTTCTGGAGATAACGGGAGTGCGGCCTGA
CGGCTACCACGAACTGGTCA

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MDLKGTTILAVKDDEGVSMAGDGQVTLGQAIVMKHGARKVRRIYKDRIIAGFAGSTADAFTLFERFEAKLEEFGGNLLRA
SVEMAKDWRKDKFLRRLEAMLLVSDGTTLLMLSGTGDVIEPDDGVAAIGSGGPYALAAARALQRHTALSAQEIVTKAMAI
AGELCVFTNDHLTVENARRA

Sequences:

>Translated_180_residues
MDLKGTTILAVKDDEGVSMAGDGQVTLGQAIVMKHGARKVRRIYKDRIIAGFAGSTADAFTLFERFEAKLEEFGGNLLRA
SVEMAKDWRKDKFLRRLEAMLLVSDGTTLLMLSGTGDVIEPDDGVAAIGSGGPYALAAARALQRHTALSAQEIVTKAMAI
AGELCVFTNDHLTVENARRA
>Mature_180_residues
MDLKGTTILAVKDDEGVSMAGDGQVTLGQAIVMKHGARKVRRIYKDRIIAGFAGSTADAFTLFERFEAKLEEFGGNLLRA
SVEMAKDWRKDKFLRRLEAMLLVSDGTTLLMLSGTGDVIEPDDGVAAIGSGGPYALAAARALQRHTALSAQEIVTKAMAI
AGELCVFTNDHLTVENARRA

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily

Homologues:

Organism=Escherichia coli, GI1790367, Length=170, Percent_Identity=58.2352941176471, Blast_Score=202, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLV_DESDG (Q30ZH5)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_388616.1
- ProteinModelPortal:   Q30ZH5
- SMR:   Q30ZH5
- STRING:   Q30ZH5
- MEROPS:   T01.007
- GeneID:   3757132
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_2124
- NMPDR:   fig|207559.3.peg.2084
- eggNOG:   COG5405
- HOGENOM:   HBG288822
- OMA:   AADICVY
- ProtClustDB:   PRK05456
- BioCyc:   DDES207559:DDE_2124-MONOMER
- HAMAP:   MF_00248
- InterPro:   IPR022281
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03692

Pfam domain/function: PF00227 Proteasome

EC number: 3.4.25.-

Molecular weight: Translated: 19328; Mature: 19328

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: ACT_SITE 6-6

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLKGTTILAVKDDEGVSMAGDGQVTLGQAIVMKHGARKVRRIYKDRIIAGFAGSTADAF
CCCCCCEEEEEECCCCCEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
TLFERFEAKLEEFGGNLLRASVEMAKDWRKDKFLRRLEAMLLVSDGTTLLMLSGTGDVIE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEECCCCEEC
PDDGVAAIGSGGPYALAAARALQRHTALSAQEIVTKAMAIAGELCVFTNDHLTVENARRA
CCCCEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEECCCEEECCCCCC
>Mature Secondary Structure
MDLKGTTILAVKDDEGVSMAGDGQVTLGQAIVMKHGARKVRRIYKDRIIAGFAGSTADAF
CCCCCCEEEEEECCCCCEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
TLFERFEAKLEEFGGNLLRASVEMAKDWRKDKFLRRLEAMLLVSDGTTLLMLSGTGDVIE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEECCCCEEC
PDDGVAAIGSGGPYALAAARALQRHTALSAQEIVTKAMAIAGELCVFTNDHLTVENARRA
CCCCEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEECCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA