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The map label for this gene is alr [H]

Identifier: 78356590

GI number: 78356590

Start: 1565671

End: 1566837

Strand: Direct

Name: alr [H]

Synonym: Dde_1547

Alternate gene names: 78356590

Gene position: 1565671-1566837 (Clockwise)

Preceding gene: 78356588

Following gene: 78356591

Centisome position: 41.97

GC content: 62.38

Gene sequence:

>1167_bases
GTGGGATATGAAGCATTTCCCGAGCCGTTGTGGGCGGAGATAGATCTCTGCGCCCTGCGGCACAATTTTTCCGCTGTACG
GTCGCACGTCGGAAAGGGTGTACGCATTATGGCAGTGGTCAAGGCCGACGCTTACGGTCACGGGGCTGTGGCCGTGGCAC
ACGAACTGTTGCGTCAGGGGGCTGATGCCTTCGGAGTGGCCAGACTGGATGAGGCAGTGGAACTGCGCGAGAACGGTATC
ACCCAGCCTGTGCTCATTTTCGGGCCCACCCCGCCGCAGAAGGCTCCGCTGCTTGCCCGCTACGGCATCATACAGACCGT
GCATTCCGATACCTATGCAGAGGCGCTGCAGGCGGCGTTGCTGGCCCAGCAGCCCCGCAGGCGGGTACAGGTGCACATAA
AGGTGGACACCGGCATGGGGCGTCTTGGGTATATCGCCACGGGAAACGGCGGTGATGTTCCGCTGGGGCAGGTGTTTGCC
GGTTTTTCTTCCCGCACCATGCTGGATGTGTGCGGTGTGTTCACCCACTTTGCCGCCAGCGATGCCGCCGACCCTGTCAC
GGCGCGCAGGCAGCTGGCCGTGTTTGAACAGGCACTGTCAGAGCTGCCTGCCGGTATGCGCGACAGGCTGTGTGTGCATG
CGGCCAACAGCGCGGCAACCATGGTCATGCCCGGTGCCCGTTTTGACATGGTGCGCCCGGGCATCATCCTGTACGGGCTC
CGCCCCTCGGCAGAGATGGACACCGCCGGTTTCGATCTGCGTCCGGTGATGAGCCTCAAAGGCCGTATAGCCAGCGTCAA
ACGTGTTCCTGCCGGATTTACGGTAAGCTACGGGCATACCCACGTGACGGCCGCCGGAACTGTCATTGCGGCAGTGCCTG
CAGGGTACGCGGACGGGTACAGCCGCCTGCTTTCGTCCTGCGGCACCATGCTGGTTCACGGCCGCCCGGCCGCAGTAACC
GGCAGGGTGTGTATGGACCAGACCATGATTGACGTGGGGCACATTGACGGAGTGCAGGAGGGGGACGAGGTTGTCCTGCT
GGGCAGGCAGGGCGCCGAAAGCGTGACGGCAGACGATCACGCCCGTCTGACTTCCACTATTAATTATGAGGTTGTCTCCC
GCATACTTGCCCGTGTGCCGCGGGTTTATGTGGAAAACGCAGAGTAA

Upstream 100 bases:

>100_bases
TTGATGTTGTTGTTGACAGTGCAACTGCAATATGTACAATTGTATTATGATAAAAAGTATTGCATTGCAATACTGTTTTG
CAGAATCAGGAGCTGTCGCT

Downstream 100 bases:

>100_bases
TGACCCGCTTGCGCCGGGCGGCGCCGCGGGATTGGTGCTTCCCCTGTCCGTACGGCAGTGCGCCGCAGACGGGGCGGTTC
AACCTTATTCCTATCGGAGG

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MGYEAFPEPLWAEIDLCALRHNFSAVRSHVGKGVRIMAVVKADAYGHGAVAVAHELLRQGADAFGVARLDEAVELRENGI
TQPVLIFGPTPPQKAPLLARYGIIQTVHSDTYAEALQAALLAQQPRRRVQVHIKVDTGMGRLGYIATGNGGDVPLGQVFA
GFSSRTMLDVCGVFTHFAASDAADPVTARRQLAVFEQALSELPAGMRDRLCVHAANSAATMVMPGARFDMVRPGIILYGL
RPSAEMDTAGFDLRPVMSLKGRIASVKRVPAGFTVSYGHTHVTAAGTVIAAVPAGYADGYSRLLSSCGTMLVHGRPAAVT
GRVCMDQTMIDVGHIDGVQEGDEVVLLGRQGAESVTADDHARLTSTINYEVVSRILARVPRVYVENAE

Sequences:

>Translated_388_residues
MGYEAFPEPLWAEIDLCALRHNFSAVRSHVGKGVRIMAVVKADAYGHGAVAVAHELLRQGADAFGVARLDEAVELRENGI
TQPVLIFGPTPPQKAPLLARYGIIQTVHSDTYAEALQAALLAQQPRRRVQVHIKVDTGMGRLGYIATGNGGDVPLGQVFA
GFSSRTMLDVCGVFTHFAASDAADPVTARRQLAVFEQALSELPAGMRDRLCVHAANSAATMVMPGARFDMVRPGIILYGL
RPSAEMDTAGFDLRPVMSLKGRIASVKRVPAGFTVSYGHTHVTAAGTVIAAVPAGYADGYSRLLSSCGTMLVHGRPAAVT
GRVCMDQTMIDVGHIDGVQEGDEVVLLGRQGAESVTADDHARLTSTINYEVVSRILARVPRVYVENAE
>Mature_387_residues
GYEAFPEPLWAEIDLCALRHNFSAVRSHVGKGVRIMAVVKADAYGHGAVAVAHELLRQGADAFGVARLDEAVELRENGIT
QPVLIFGPTPPQKAPLLARYGIIQTVHSDTYAEALQAALLAQQPRRRVQVHIKVDTGMGRLGYIATGNGGDVPLGQVFAG
FSSRTMLDVCGVFTHFAASDAADPVTARRQLAVFEQALSELPAGMRDRLCVHAANSAATMVMPGARFDMVRPGIILYGLR
PSAEMDTAGFDLRPVMSLKGRIASVKRVPAGFTVSYGHTHVTAAGTVIAAVPAGYADGYSRLLSSCGTMLVHGRPAAVTG
RVCMDQTMIDVGHIDGVQEGDEVVLLGRQGAESVTADDHARLTSTINYEVVSRILARVPRVYVENAE

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=378, Percent_Identity=35.978835978836, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1787439, Length=380, Percent_Identity=34.2105263157895, Blast_Score=164, Evalue=6e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 41367; Mature: 41236

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYEAFPEPLWAEIDLCALRHNFSAVRSHVGKGVRIMAVVKADAYGHGAVAVAHELLRQG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHCC
ADAFGVARLDEAVELRENGITQPVLIFGPTPPQKAPLLARYGIIQTVHSDTYAEALQAAL
CCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHH
LAQQPRRRVQVHIKVDTGMGRLGYIATGNGGDVPLGQVFAGFSSRTMLDVCGVFTHFAAS
HHHCCCCEEEEEEEEECCCCCEEEEEECCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCC
DAADPVTARRQLAVFEQALSELPAGMRDRLCVHAANSAATMVMPGARFDMVRPGIILYGL
CCCCCHHHHHHHHHHHHHHHHCCCCCHHCEEEEECCCCEEEEECCCCCCCCCCCEEEEEC
RPSAEMDTAGFDLRPVMSLKGRIASVKRVPAGFTVSYGHTHVTAAGTVIAAVPAGYADGY
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCEEEEECCCCCHHHH
SRLLSSCGTMLVHGRPAAVTGRVCMDQTMIDVGHIDGVQEGDEVVLLGRQGAESVTADDH
HHHHHHCCCEEECCCCCCEECHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCH
ARLTSTINYEVVSRILARVPRVYVENAE
HHHHHHCCHHHHHHHHHHCCCCEECCCC
>Mature Secondary Structure 
GYEAFPEPLWAEIDLCALRHNFSAVRSHVGKGVRIMAVVKADAYGHGAVAVAHELLRQG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHCC
ADAFGVARLDEAVELRENGITQPVLIFGPTPPQKAPLLARYGIIQTVHSDTYAEALQAAL
CCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHH
LAQQPRRRVQVHIKVDTGMGRLGYIATGNGGDVPLGQVFAGFSSRTMLDVCGVFTHFAAS
HHHCCCCEEEEEEEEECCCCCEEEEEECCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCC
DAADPVTARRQLAVFEQALSELPAGMRDRLCVHAANSAATMVMPGARFDMVRPGIILYGL
CCCCCHHHHHHHHHHHHHHHHCCCCCHHCEEEEECCCCEEEEECCCCCCCCCCCEEEEEC
RPSAEMDTAGFDLRPVMSLKGRIASVKRVPAGFTVSYGHTHVTAAGTVIAAVPAGYADGY
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCEEEEECCCCCHHHH
SRLLSSCGTMLVHGRPAAVTGRVCMDQTMIDVGHIDGVQEGDEVVLLGRQGAESVTADDH
HHHHHHCCCEEECCCCCCEECHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCH
ARLTSTINYEVVSRILARVPRVYVENAE
HHHHHHCCHHHHHHHHHHCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA