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The map label for this gene is siaP [H]

Identifier: 78356591

GI number: 78356591

Start: 1566944

End: 1567981

Strand: Direct

Name: siaP [H]

Synonym: Dde_1548

Alternate gene names: 78356591

Gene position: 1566944-1567981 (Clockwise)

Preceding gene: 78356590

Following gene: 78356592

Centisome position: 42.01

GC content: 55.3

Gene sequence:

>1038_bases
ATGAAACCATCGGGACATTTTTTCAGAGGCATGAAGCGTTTTATGGCCGCCGCACTGGTCGTGCTGGCTGTTCCGGCGCT
GGCTGCGGCCGCCATGACGGTCAAGATGAGTTACAACGGGCCGCCCAGTCTGGAAGACAACGCCGTGCATGCTTTTGCCA
CCACTTTCAAGGAACTGGTTGAAAAAGAGTCCGGAGGCGGCATTGTCATCGACCTGTATCCCAACAGTCAGCTGGGTAAT
GAGCAGCAGCGCATGGAACAGGTGATGACCGGTCCCATGATCAATGTGGCTTCTTTCGGCGGTATGGAGACCGTGTTTCC
TGAAATGTTCGCCACCAACGTACCCTTCATGTTTGAAAGCTACGCTGCGGCACATGAATTTTTCGACAACAGCTCTTTTA
TGGATAAAGCCGGAAAAGAGCTGCGTTCGCGCACCGGCATCGAGCTGCTGGCCGTGGTGGAAGAGGGGGGCTTCATTGCC
TTTACTTCCAAAAAGCCCGTCAGGTCTCCGGCTGATTTCAAGGGTATGAAATTCCGCGCCATGGATGCCAGCCAGGTAGC
CATGTACGAAGCCTTCGGAGCTTCCGGAACTCCTATTCCGTGGACCGAGGTGTATCTTGCGCTTAAAACCGGCGTGGCAG
ACGGCCAGATGAACCCCCCTACCTATATCATCATCGGCAGCCTGTACGAGGTGCAGGACCATCTCACCCTTGCCAACGTC
CAGTATTCCGATCAGTTCCTGTTGATCAACGGTGAACTGCTTGACTCTCTTCCCGACAGCCAGCGTCAGGTAATCCGTAA
GGCGGCGCACGAGGCAAACGTCAAGACCCGCCAGTTTGTGGAGTCTCAGGTGGACGAGCGTGTGAAGTTTCTGGCCAGCA
AGGGCATGACCGTTTACACCCCCACCGCGGAAGAGCTGGCGCAGTTCAAGGAACTTGGCAGTCCTTCCTACATCAAGTGG
CTCAGCGGACAGATTGACACGGCATGGATAGACCATGCCATGGAAGACGCCCGCAAGGCCAATGAGGCAGTGAAATAG

Upstream 100 bases:

>100_bases
GCTTGCGCCGGGCGGCGCCGCGGGATTGGTGCTTCCCCTGTCCGTACGGCAGTGCGCCGCAGACGGGGCGGTTCAACCTT
ATTCCTATCGGAGGATGTCT

Downstream 100 bases:

>100_bases
ATGGGCCGTGTGGCGGACGTCTGTCATAAGGCTTCCGACCTGCTGGAGCGCCTCTGCCTTATGGGGGCGGGGGCTCTCCT
CGTGGTCAACCTGCTGTCGG

Product: TRAP dicarboxylate transporter subunit DctP

Products: NA

Alternate protein names: Extracytoplasmic solute receptor protein siaP; N-acetylneuraminic-binding protein; Neu5Ac-binding protein [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MKPSGHFFRGMKRFMAAALVVLAVPALAAAAMTVKMSYNGPPSLEDNAVHAFATTFKELVEKESGGGIVIDLYPNSQLGN
EQQRMEQVMTGPMINVASFGGMETVFPEMFATNVPFMFESYAAAHEFFDNSSFMDKAGKELRSRTGIELLAVVEEGGFIA
FTSKKPVRSPADFKGMKFRAMDASQVAMYEAFGASGTPIPWTEVYLALKTGVADGQMNPPTYIIIGSLYEVQDHLTLANV
QYSDQFLLINGELLDSLPDSQRQVIRKAAHEANVKTRQFVESQVDERVKFLASKGMTVYTPTAEELAQFKELGSPSYIKW
LSGQIDTAWIDHAMEDARKANEAVK

Sequences:

>Translated_345_residues
MKPSGHFFRGMKRFMAAALVVLAVPALAAAAMTVKMSYNGPPSLEDNAVHAFATTFKELVEKESGGGIVIDLYPNSQLGN
EQQRMEQVMTGPMINVASFGGMETVFPEMFATNVPFMFESYAAAHEFFDNSSFMDKAGKELRSRTGIELLAVVEEGGFIA
FTSKKPVRSPADFKGMKFRAMDASQVAMYEAFGASGTPIPWTEVYLALKTGVADGQMNPPTYIIIGSLYEVQDHLTLANV
QYSDQFLLINGELLDSLPDSQRQVIRKAAHEANVKTRQFVESQVDERVKFLASKGMTVYTPTAEELAQFKELGSPSYIKW
LSGQIDTAWIDHAMEDARKANEAVK
>Mature_345_residues
MKPSGHFFRGMKRFMAAALVVLAVPALAAAAMTVKMSYNGPPSLEDNAVHAFATTFKELVEKESGGGIVIDLYPNSQLGN
EQQRMEQVMTGPMINVASFGGMETVFPEMFATNVPFMFESYAAAHEFFDNSSFMDKAGKELRSRTGIELLAVVEEGGFIA
FTSKKPVRSPADFKGMKFRAMDASQVAMYEAFGASGTPIPWTEVYLALKTGVADGQMNPPTYIIIGSLYEVQDHLTLANV
QYSDQFLLINGELLDSLPDSQRQVIRKAAHEANVKTRQFVESQVDERVKFLASKGMTVYTPTAEELAQFKELGSPSYIKW
LSGQIDTAWIDHAMEDARKANEAVK

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid. This protein specifically binds sialic acid [H]

COG id: COG1638

COG function: function code G; TRAP-type C4-dicarboxylate transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 7 family [H]

Homologues:

Organism=Escherichia coli, GI1790004, Length=296, Percent_Identity=28.3783783783784, Blast_Score=124, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018389
- InterPro:   IPR004682 [H]

Pfam domain/function: PF03480 SBP_bac_7 [H]

EC number: NA

Molecular weight: Translated: 38007; Mature: 38007

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPSGHFFRGMKRFMAAALVVLAVPALAAAAMTVKMSYNGPPSLEDNAVHAFATTFKELV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHH
EKESGGGIVIDLYPNSQLGNEQQRMEQVMTGPMINVASFGGMETVFPEMFATNVPFMFES
HCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCEEHHHCCCHHHHHHHHHHCCCCHHHHH
YAAAHEFFDNSSFMDKAGKELRSRTGIELLAVVEEGGFIAFTSKKPVRSPADFKGMKFRA
HHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEECCCEEEEECCCCCCCCCCCCCCEEEE
MDASQVAMYEAFGASGTPIPWTEVYLALKTGVADGQMNPPTYIIIGSLYEVQDHLTLANV
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECHHHHHHCEEEEEE
QYSDQFLLINGELLDSLPDSQRQVIRKAAHEANVKTRQFVESQVDERVKFLASKGMTVYT
EECCEEEEEECHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEC
PTAEELAQFKELGSPSYIKWLSGQIDTAWIDHAMEDARKANEAVK
CCHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKPSGHFFRGMKRFMAAALVVLAVPALAAAAMTVKMSYNGPPSLEDNAVHAFATTFKELV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHH
EKESGGGIVIDLYPNSQLGNEQQRMEQVMTGPMINVASFGGMETVFPEMFATNVPFMFES
HCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCEEHHHCCCHHHHHHHHHHCCCCHHHHH
YAAAHEFFDNSSFMDKAGKELRSRTGIELLAVVEEGGFIAFTSKKPVRSPADFKGMKFRA
HHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEECCCEEEEECCCCCCCCCCCCCCEEEE
MDASQVAMYEAFGASGTPIPWTEVYLALKTGVADGQMNPPTYIIIGSLYEVQDHLTLANV
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECHHHHHHCEEEEEE
QYSDQFLLINGELLDSLPDSQRQVIRKAAHEANVKTRQFVESQVDERVKFLASKGMTVYT
EECCEEEEEECHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEC
PTAEELAQFKELGSPSYIKWLSGQIDTAWIDHAMEDARKANEAVK
CCHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA