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The map label for this gene is glmM

Identifier: 78356562

GI number: 78356562

Start: 1536655

End: 1538007

Strand: Direct

Name: glmM

Synonym: Dde_1517

Alternate gene names: 78356562

Gene position: 1536655-1538007 (Clockwise)

Preceding gene: 78356561

Following gene: 78356563

Centisome position: 41.19

GC content: 57.8

Gene sequence:

>1353_bases
ATGACGACACGTCTTTTCGGAACTGACGGCCTGCGCGGGCAGGTAAATATATATCCCATGGTGCCGGACATGGCTCTTCG
TCTGGGGCTGGCGGCCGGTACTTTTTTTCGCAACGGCAATAAGCGGCATCGGGTTGTTATCGGCAAAGACACGCGTCTTT
CCGGCTATGTATTTGAAATGGCGCTCACATCAGGTCTGTGCGCTGCCGGTATGGACGTTTTTCTGGTGGGCCCCCTGCCT
ACGCCCGCCGTGGCGTTTCTTACCCGCAACATGCGGGCTGACCTCGGTGTTGTTATCTCGGCATCGCACAATCCCTTCCA
TGACAACGGCATAAAATTTTTTGATAAAGACGGATTCAAGCTGCCGGATTCGCAGGAAGATGCCATAACTGAAATGGTTC
TGAACCAGAACCACCGCTGGGACTACCCGGAGCCGGAACGTGTGGGCAGAGCCCATAAGATTCAGGACGCACCCGGCCGG
TACATAGTGTACCTGAAGAACAGCTTTCCCAGCACATTGACTCTGGACGGCATGAAGGTGGTGCTTGACTGCGCCAACGG
CGCCAACTACCGCGTGGCTCCTCTGGCTCTGGAAGAGCTGGGTGCCGAAGTCATCAGAATAGGCACCAGTCCTGACGGGC
TGAACATCAACCACAAATGCGGCTCGCTGTACCCCGAACTTGCCGCGCAGCGCGTGCGTGAAACGGGTGCGGATATCGGC
CTTGCCCTTGATGGTGACGCGGACAGGCTGATTGTGGTGGATGAAAAAGGCACCGTGCTGGACGGTGACCAGATTATGGC
CATATGTGCCATGGATATGATGGAAAAAGGCCGCCTGCCGGAAAACAGACTGGTGGCCACCGTCATGAGCAATATGGCGC
TTGAGGTGTTTATGAAAGAGCGCGGTGGTTCGTTGCTGCGCACTCCCGTGGGCGACCGGCATGTGGTGGAAGCCATGCGC
CGGACAGGTGCCGCCATGGGCGGTGAACAGTCCGGACACCTTGTTTTTATGGAATACGGAACCACCGGCGACGGCCTTTT
GGCCGCCTTGCAGCTGCTCAGAATCATGCGCGAAAAGAACAGGCCGCTTTCAGAGCTTGCGGGGCTGCTTACACCGTTTC
CGCAACAGCTCATCAACGTCCACGTCCAGCGCAAGATTCCCTTTGAACAGTGCCCCGAAATCGGCAGGGCCGTTGAGCAG
GCCGAAAAAGAACTTGCCGGCCGCGGCCGGGTGTTGCTGCGCTATTCGGGTACCGAATCTGTGGCGCGGGTGATGGTGGA
AGGTGAAGATGATGCTCTGGTGGGCAGACTGGCCGCCGGTCTGGCGGAAACCCTTCAGCAGCATCTGCGCTGA

Upstream 100 bases:

>100_bases
TATCAGCATAAGCGGCAGGTAGCGCTCTTCAGCGCGGCTTGTCTGCTTTTTCATGCGTGTCCGCATGTTGCGGAGCACCC
ACAATGAGGAGTCGTACAGT

Downstream 100 bases:

>100_bases
CCGGTTGAAGGATGCAAGTCTAAGGAGACTGTCATGCTGATACGCAAAGTAGTCATTCCCGTTGCCGGCTGGGGCACGCG
TTCGCTGCCTGCCACTAAAA

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MTTRLFGTDGLRGQVNIYPMVPDMALRLGLAAGTFFRNGNKRHRVVIGKDTRLSGYVFEMALTSGLCAAGMDVFLVGPLP
TPAVAFLTRNMRADLGVVISASHNPFHDNGIKFFDKDGFKLPDSQEDAITEMVLNQNHRWDYPEPERVGRAHKIQDAPGR
YIVYLKNSFPSTLTLDGMKVVLDCANGANYRVAPLALEELGAEVIRIGTSPDGLNINHKCGSLYPELAAQRVRETGADIG
LALDGDADRLIVVDEKGTVLDGDQIMAICAMDMMEKGRLPENRLVATVMSNMALEVFMKERGGSLLRTPVGDRHVVEAMR
RTGAAMGGEQSGHLVFMEYGTTGDGLLAALQLLRIMREKNRPLSELAGLLTPFPQQLINVHVQRKIPFEQCPEIGRAVEQ
AEKELAGRGRVLLRYSGTESVARVMVEGEDDALVGRLAAGLAETLQQHLR

Sequences:

>Translated_450_residues
MTTRLFGTDGLRGQVNIYPMVPDMALRLGLAAGTFFRNGNKRHRVVIGKDTRLSGYVFEMALTSGLCAAGMDVFLVGPLP
TPAVAFLTRNMRADLGVVISASHNPFHDNGIKFFDKDGFKLPDSQEDAITEMVLNQNHRWDYPEPERVGRAHKIQDAPGR
YIVYLKNSFPSTLTLDGMKVVLDCANGANYRVAPLALEELGAEVIRIGTSPDGLNINHKCGSLYPELAAQRVRETGADIG
LALDGDADRLIVVDEKGTVLDGDQIMAICAMDMMEKGRLPENRLVATVMSNMALEVFMKERGGSLLRTPVGDRHVVEAMR
RTGAAMGGEQSGHLVFMEYGTTGDGLLAALQLLRIMREKNRPLSELAGLLTPFPQQLINVHVQRKIPFEQCPEIGRAVEQ
AEKELAGRGRVLLRYSGTESVARVMVEGEDDALVGRLAAGLAETLQQHLR
>Mature_449_residues
TTRLFGTDGLRGQVNIYPMVPDMALRLGLAAGTFFRNGNKRHRVVIGKDTRLSGYVFEMALTSGLCAAGMDVFLVGPLPT
PAVAFLTRNMRADLGVVISASHNPFHDNGIKFFDKDGFKLPDSQEDAITEMVLNQNHRWDYPEPERVGRAHKIQDAPGRY
IVYLKNSFPSTLTLDGMKVVLDCANGANYRVAPLALEELGAEVIRIGTSPDGLNINHKCGSLYPELAAQRVRETGADIGL
ALDGDADRLIVVDEKGTVLDGDQIMAICAMDMMEKGRLPENRLVATVMSNMALEVFMKERGGSLLRTPVGDRHVVEAMRR
TGAAMGGEQSGHLVFMEYGTTGDGLLAALQLLRIMREKNRPLSELAGLLTPFPQQLINVHVQRKIPFEQCPEIGRAVEQA
EKELAGRGRVLLRYSGTESVARVMVEGEDDALVGRLAAGLAETLQQHLR

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=446, Percent_Identity=47.3094170403587, Blast_Score=374, Evalue=1e-104,
Organism=Escherichia coli, GI1788361, Length=435, Percent_Identity=29.1954022988506, Blast_Score=126, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17535441, Length=375, Percent_Identity=25.3333333333333, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_DESDG (Q311T0)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_388011.1
- ProteinModelPortal:   Q311T0
- SMR:   Q311T0
- STRING:   Q311T0
- GeneID:   3756033
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_1517
- NMPDR:   fig|207559.3.peg.724
- eggNOG:   COG1109
- HOGENOM:   HBG644964
- OMA:   VHDRYIE
- ProtClustDB:   PRK14314
- BioCyc:   DDES207559:DDE_1517-MONOMER
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 49250; Mature: 49118

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 102-102

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRLFGTDGLRGQVNIYPMVPDMALRLGLAAGTFFRNGNKRHRVVIGKDTRLSGYVFEM
CCEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHH
ALTSGLCAAGMDVFLVGPLPTPAVAFLTRNMRADLGVVISASHNPFHDNGIKFFDKDGFK
HHHCCHHHCCCCEEEECCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEECCCCCC
LPDSQEDAITEMVLNQNHRWDYPEPERVGRAHKIQDAPGRYIVYLKNSFPSTLTLDGMKV
CCCCHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCEEEEEECCCCCEEEECCEEE
VLDCANGANYRVAPLALEELGAEVIRIGTSPDGLNINHKCGSLYPELAAQRVRETGADIG
EEECCCCCCEEEHHHHHHHCCCEEEEECCCCCCCCCCCHHCCCCHHHHHHHHHHCCCCEE
LALDGDADRLIVVDEKGTVLDGDQIMAICAMDMMEKGRLPENRLVATVMSNMALEVFMKE
EEECCCCCEEEEECCCCCEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
RGGSLLRTPVGDRHVVEAMRRTGAAMGGEQSGHLVFMEYGTTGDGLLAALQLLRIMREKN
CCCCEEECCCCCHHHHHHHHHHCHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCC
RPLSELAGLLTPFPQQLINVHVQRKIPFEQCPEIGRAVEQAEKELAGRGRVLLRYSGTES
CCHHHHHHHHCCCHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHH
VARVMVEGEDDALVGRLAAGLAETLQQHLR
HEEEEEECCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTRLFGTDGLRGQVNIYPMVPDMALRLGLAAGTFFRNGNKRHRVVIGKDTRLSGYVFEM
CEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHH
ALTSGLCAAGMDVFLVGPLPTPAVAFLTRNMRADLGVVISASHNPFHDNGIKFFDKDGFK
HHHCCHHHCCCCEEEECCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEECCCCCC
LPDSQEDAITEMVLNQNHRWDYPEPERVGRAHKIQDAPGRYIVYLKNSFPSTLTLDGMKV
CCCCHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCEEEEEECCCCCEEEECCEEE
VLDCANGANYRVAPLALEELGAEVIRIGTSPDGLNINHKCGSLYPELAAQRVRETGADIG
EEECCCCCCEEEHHHHHHHCCCEEEEECCCCCCCCCCCHHCCCCHHHHHHHHHHCCCCEE
LALDGDADRLIVVDEKGTVLDGDQIMAICAMDMMEKGRLPENRLVATVMSNMALEVFMKE
EEECCCCCEEEEECCCCCEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
RGGSLLRTPVGDRHVVEAMRRTGAAMGGEQSGHLVFMEYGTTGDGLLAALQLLRIMREKN
CCCCEEECCCCCHHHHHHHHHHCHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCC
RPLSELAGLLTPFPQQLINVHVQRKIPFEQCPEIGRAVEQAEKELAGRGRVLLRYSGTES
CCHHHHHHHHCCCHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHH
VARVMVEGEDDALVGRLAAGLAETLQQHLR
HEEEEEECCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA