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The map label for this gene is oppF2 [H]

Identifier: 78356372

GI number: 78356372

Start: 1345263

End: 1345865

Strand: Reverse

Name: oppF2 [H]

Synonym: Dde_1325

Alternate gene names: 78356372

Gene position: 1345865-1345263 (Counterclockwise)

Preceding gene: 78356373

Following gene: 78356371

Centisome position: 36.08

GC content: 61.69

Gene sequence:

>603_bases
ATGCTTGAAGGCCGCGGATTGGGCTTCCGCTACAACCGCCGCGAAAACTGGCTTTTCCGCGGGCTGGACATAACCGTCGC
CGCTGGAGAAAGAGTGGGGCTGCCCGGACCGAGCGGGCGCGGCAAGTCCACACTGGCCAGAGTTCTGAGCAGTTACCTGA
CACCGCAGGAAGGCTCGGTTTCCGTTGACGGAGAAAGGTACGTCCGCGGGAACTTCAATCCCGTCCAGCTGCTTTTCCAG
CATCCGGAACTGGCTGTGAATCCCCGCTGGCAGATACGTGACATTCTGGCCGAGGCAGGCCCCCCCCAGCCCCGCCTGCT
TGAAAGGCTGGGCATAGCCGGTGCGTGGCTTGCCCGGTATCCGCATGAACTTTCCGGCGGCGAACTGCAACGGGTCTGCC
TTGCACGGGCGCTGGACAGGCGTACACGCTATCTGCTGTGCGATGAAATGACATCCATGCTGGATGCCCTGACGCAGGCA
ACCATCTGGAAAAGCGTGCTGGAAACAGCCGCAGAGCGGAATATCGGCATGCTGGTCATCAGCCACGATGCCGCGCTGCT
GGACAGAATCTGCAGCCGCACCGTCAATGCTTTCAGCGCCTAG

Upstream 100 bases:

>100_bases
GGTTGCCCTTTCAGCGGGGCATGCCTGCGCAGCAACGGCAGCTGCCGCGAAACCCTGCCGGAACTGACGCCGCTGTCCGG
CGGTAAAGTGAGGTGCTGGA

Downstream 100 bases:

>100_bases
CAGCCCCACCGGCGCTGCGCCTTTGCACCGGATGCATCTGCTCTATTCCAAAACAACGCAGGGTGTGGCACCATGGCACA
CGACGTACGGCTCCGGACGG

Product: ATPase

Products: Ni2; [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MLEGRGLGFRYNRRENWLFRGLDITVAAGERVGLPGPSGRGKSTLARVLSSYLTPQEGSVSVDGERYVRGNFNPVQLLFQ
HPELAVNPRWQIRDILAEAGPPQPRLLERLGIAGAWLARYPHELSGGELQRVCLARALDRRTRYLLCDEMTSMLDALTQA
TIWKSVLETAAERNIGMLVISHDAALLDRICSRTVNAFSA

Sequences:

>Translated_200_residues
MLEGRGLGFRYNRRENWLFRGLDITVAAGERVGLPGPSGRGKSTLARVLSSYLTPQEGSVSVDGERYVRGNFNPVQLLFQ
HPELAVNPRWQIRDILAEAGPPQPRLLERLGIAGAWLARYPHELSGGELQRVCLARALDRRTRYLLCDEMTSMLDALTQA
TIWKSVLETAAERNIGMLVISHDAALLDRICSRTVNAFSA
>Mature_200_residues
MLEGRGLGFRYNRRENWLFRGLDITVAAGERVGLPGPSGRGKSTLARVLSSYLTPQEGSVSVDGERYVRGNFNPVQLLFQ
HPELAVNPRWQIRDILAEAGPPQPRLLERLGIAGAWLARYPHELSGGELQRVCLARALDRRTRYLLCDEMTSMLDALTQA
TIWKSVLETAAERNIGMLVISHDAALLDRICSRTVNAFSA

Specific function: Part of a transport system that may be involved in oligopeptide uptake. Probably responsible for energy coupling to the transport system. Important for S.aureus growth and survival during the infection process [H]

COG id: COG1124

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI42741659, Length=207, Percent_Identity=31.4009661835749, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1789891, Length=207, Percent_Identity=34.2995169082126, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788506, Length=225, Percent_Identity=33.7777777777778, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI145693107, Length=187, Percent_Identity=34.2245989304813, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1787500, Length=198, Percent_Identity=30.3030303030303, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1787758, Length=220, Percent_Identity=30.4545454545455, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1786253, Length=198, Percent_Identity=33.3333333333333, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1787547, Length=218, Percent_Identity=26.605504587156, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786398, Length=206, Percent_Identity=31.0679611650485, Blast_Score=84, Evalue=5e-18,
Organism=Escherichia coli, GI1787029, Length=196, Percent_Identity=32.1428571428571, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1789672, Length=197, Percent_Identity=31.9796954314721, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1789962, Length=197, Percent_Identity=26.3959390862944, Blast_Score=80, Evalue=6e-17,
Organism=Escherichia coli, GI48994883, Length=203, Percent_Identity=30.0492610837438, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI1788225, Length=206, Percent_Identity=30.0970873786408, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787370, Length=185, Percent_Identity=31.8918918918919, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786698, Length=184, Percent_Identity=31.5217391304348, Blast_Score=79, Evalue=1e-16,
Organism=Escherichia coli, GI87081709, Length=180, Percent_Identity=28.8888888888889, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1789963, Length=214, Percent_Identity=30.3738317757009, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1787089, Length=198, Percent_Identity=33.8383838383838, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1787759, Length=201, Percent_Identity=30.3482587064677, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87081791, Length=193, Percent_Identity=29.5336787564767, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1786703, Length=203, Percent_Identity=33.4975369458128, Blast_Score=74, Evalue=5e-15,
Organism=Escherichia coli, GI1786872, Length=176, Percent_Identity=30.6818181818182, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1788165, Length=173, Percent_Identity=33.5260115606936, Blast_Score=71, Evalue=4e-14,
Organism=Escherichia coli, GI1787164, Length=197, Percent_Identity=30.9644670050761, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1786563, Length=173, Percent_Identity=32.3699421965318, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787112, Length=193, Percent_Identity=29.5336787564767, Blast_Score=68, Evalue=3e-13,
Organism=Escherichia coli, GI1787548, Length=238, Percent_Identity=26.890756302521, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI87081782, Length=189, Percent_Identity=32.2751322751323, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1789032, Length=190, Percent_Identity=31.5789473684211, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788761, Length=190, Percent_Identity=29.4736842105263, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786345, Length=209, Percent_Identity=30.1435406698565, Blast_Score=64, Evalue=5e-12,
Organism=Escherichia coli, GI1790534, Length=191, Percent_Identity=32.4607329842932, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI87082267, Length=182, Percent_Identity=31.3186813186813, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1787105, Length=183, Percent_Identity=27.8688524590164, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1789890, Length=190, Percent_Identity=28.4210526315789, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1788644, Length=213, Percent_Identity=28.169014084507, Blast_Score=60, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI115533592, Length=196, Percent_Identity=29.0816326530612, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324985, Length=210, Percent_Identity=26.6666666666667, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323217, Length=200, Percent_Identity=31, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17136662, Length=217, Percent_Identity=29.4930875576037, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641565, Length=187, Percent_Identity=30.4812834224599, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24666836, Length=202, Percent_Identity=27.7227722772277, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 22271; Mature: 22271

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEGRGLGFRYNRRENWLFRGLDITVAAGERVGLPGPSGRGKSTLARVLSSYLTPQEGSV
CCCCCCCCEEECCCCCCEEECCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCE
SVDGERYVRGNFNPVQLLFQHPELAVNPRWQIRDILAEAGPPQPRLLERLGIAGAWLARY
EECCCEEECCCCCHHHHEEECCCCCCCCCHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHC
PHELSGGELQRVCLARALDRRTRYLLCDEMTSMLDALTQATIWKSVLETAAERNIGMLVI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
SHDAALLDRICSRTVNAFSA
ECCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLEGRGLGFRYNRRENWLFRGLDITVAAGERVGLPGPSGRGKSTLARVLSSYLTPQEGSV
CCCCCCCCEEECCCCCCEEECCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCE
SVDGERYVRGNFNPVQLLFQHPELAVNPRWQIRDILAEAGPPQPRLLERLGIAGAWLARY
EECCCEEECCCCCHHHHEEECCCCCCCCCHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHC
PHELSGGELQRVCLARALDRRTRYLLCDEMTSMLDALTQATIWKSVLETAAERNIGMLVI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
SHDAALLDRICSRTVNAFSA
ECCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; ATP; H2O [C]

Specific reaction: Ni2+ [Periplasm] + ATP + H2O = Ni2+ [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA