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The map label for this gene is siaT [H]

Identifier: 78356321

GI number: 78356321

Start: 1292279

End: 1294186

Strand: Reverse

Name: siaT [H]

Synonym: Dde_1274

Alternate gene names: 78356321

Gene position: 1294186-1292279 (Counterclockwise)

Preceding gene: 78356322

Following gene: 78356320

Centisome position: 34.69

GC content: 58.65

Gene sequence:

>1908_bases
ATGTCAGATCCCAACGTCACAGCCACCATCATGAACGCTCAGGGCGAATGCTCCAGCGGCTCTCTGGAAAGCCGCCCCGG
AATACTGGGCTGGCTTGATGCCAACTTTGAAAAGCCGTTTCTGGTTGCAGGCATGCTGGCCATCATCTTCATCATCACCT
TCCAGACCCTGTACCGCTACATCGGCGTCTACCTGCACGAAGGCGCCGCAGCCGCCGTCTGGACAGAAGAAATGGCACGT
TTCATCTTCATCTGGATATCGTATCTGGCTGTGCCTGTGGCCATTAAAAACCGCTCAAGCATCCGCGTCGACATTATTTT
CGACAGGCTGCCCGTCAGGTTTCAGAATATATCGTGGATCATCGTGGACGTGTGTTTTCTCACACTGGCAGCCACCGTGC
TCTGGCAGTCGCTTGATCTCATCAAAATGCAGCTGACCTATCCGCAGACATCTCCCGCTCTGCAGCTGCCCTACTATATT
CCGTACCTTGTGCTGCCTGTCAGCTTCGGGCTGATGGCCGTGCGGCTGCTGCAGGACCTTGCCGGACAGGTACGCATCTG
CGGTGCGGCGGATACCGTTATCGGCCTTATCCTGTGTGCGGTACTGGCCGCCCCCCTGTTCATCGCCGACTACATCGACC
CGCTGCCGGTACTTTTCGGCTACTTTGCCCTGTTTCTGGTGGTGGGCGTGCCCATTGCCATAGGTCTGGGGCTGGCTGCG
CTGGCCACCATCGTGGCCGCAGGCAGCCTGCCCATAGACTATGTGGCCCAGATTGCCTTCACGTCCATAGACAGCTTTCC
CATCATGGCCATTCCGTTCTTCATCGCCGCGGGAGTGTTCATGGGTGCCGGCGGGCTTTCGCGCCGTCTGCTGAACCTTG
CCGATGAAATGCTGGGCGCATTGCCCGGCGGCATGGCTCTGGCCACCATCGGCACATGCATGTTCTTTGCCGCCATCAGC
GGTTCCGGCCCCGCCACCGTTGCCGCCATCGGCTCGCTGACTATTCCCGCCATGGTGGAACGCGGCTACTGCAAATACTT
TTCTGCAGCCATTGTGGCCGCCGCCGGAGCCATCGGCGTCATGATTCCTCCCAGCAACCCGTTTGTGGTCTACGGCGTTT
CCGCTCAGGCATCCATCGGCAAGCTTTTCATGGGCGGCATCGTGCCGGGCCTGCTGACCGGTCTTGCCCTTATGGCGTAC
AGCTACTGGTACTCCAAAAAGCGCGGCTGGAAAGGAGAAGTACGCGATCGCAACCTGAAGACCTTCATGCATGCCGTATG
GGAAGCAAAGTGGGCTCTTATGGTGCCGGTCATCGTGCTGGGCGGCATATACGGCGGCATAATGACCCCCACGGAAGCAG
CGGCACTGGCGGCCTTCTACGGCCTCATCATCGGCTGCTTCGTGCACCGCGAACTGAGCTGCGGCAGCTTTTACGACTGT
GTGGTCGAAGCGGCCGGCACATCCGCCATGGTTATCGTGCTCATGTCCATGGCCACCATCTTCGGCAACATAATGACCAT
CGAAGAAGTGCCCACCACCATTGCACAGGCCATGCTGGGCCTGACCACAGACAAAATAGCCATCCTGCTCATGATCAACG
TGCTGCTGCTCATCATCGGCACGTTCATGGAAGCTCTGGCCGCCATTGTCATACTGACTCCCATCCTGCTGCCCATTGTG
CTCAAGGTCGGCGTAGACCCCGTACACTTCGGCATCATCATGGTGGTCAACCTTGCCATCGGGTTCGTCACACCGCCGGT
CGGGGTCAACCTCTTTGTGGCAAGCGGCGTTGCCAACGCCAAAATCGAACAGTTGTCCAAGGTGGTTCTGCCGCTCATCG
CGCTCATGCTGGCGGTGCTGCTGATCACCACCTACGTTCCCGCAATTCCCATGTTCTTTGCGGGCTGA

Upstream 100 bases:

>100_bases
GGTGCAGGAAACCCAGCAGTAAACAGAAACCGGGGCAGGGGGCCTGCCCGCTTCCTGCCCCGGAAAGCCGCTTTTCCGAC
AACGCAACCAAGAGGTCATA

Downstream 100 bases:

>100_bases
TGAAAGCACGGCGCACGGCCGGTGTCCTGCACCGCCCCGGGCGCAGCATATACACACTCAACAGAACTCAGACGAATACA
CTCAGGAGAAAAAACCATGC

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 635; Mature: 634

Protein sequence:

>635_residues
MSDPNVTATIMNAQGECSSGSLESRPGILGWLDANFEKPFLVAGMLAIIFIITFQTLYRYIGVYLHEGAAAAVWTEEMAR
FIFIWISYLAVPVAIKNRSSIRVDIIFDRLPVRFQNISWIIVDVCFLTLAATVLWQSLDLIKMQLTYPQTSPALQLPYYI
PYLVLPVSFGLMAVRLLQDLAGQVRICGAADTVIGLILCAVLAAPLFIADYIDPLPVLFGYFALFLVVGVPIAIGLGLAA
LATIVAAGSLPIDYVAQIAFTSIDSFPIMAIPFFIAAGVFMGAGGLSRRLLNLADEMLGALPGGMALATIGTCMFFAAIS
GSGPATVAAIGSLTIPAMVERGYCKYFSAAIVAAAGAIGVMIPPSNPFVVYGVSAQASIGKLFMGGIVPGLLTGLALMAY
SYWYSKKRGWKGEVRDRNLKTFMHAVWEAKWALMVPVIVLGGIYGGIMTPTEAAALAAFYGLIIGCFVHRELSCGSFYDC
VVEAAGTSAMVIVLMSMATIFGNIMTIEEVPTTIAQAMLGLTTDKIAILLMINVLLLIIGTFMEALAAIVILTPILLPIV
LKVGVDPVHFGIIMVVNLAIGFVTPPVGVNLFVASGVANAKIEQLSKVVLPLIALMLAVLLITTYVPAIPMFFAG

Sequences:

>Translated_635_residues
MSDPNVTATIMNAQGECSSGSLESRPGILGWLDANFEKPFLVAGMLAIIFIITFQTLYRYIGVYLHEGAAAAVWTEEMAR
FIFIWISYLAVPVAIKNRSSIRVDIIFDRLPVRFQNISWIIVDVCFLTLAATVLWQSLDLIKMQLTYPQTSPALQLPYYI
PYLVLPVSFGLMAVRLLQDLAGQVRICGAADTVIGLILCAVLAAPLFIADYIDPLPVLFGYFALFLVVGVPIAIGLGLAA
LATIVAAGSLPIDYVAQIAFTSIDSFPIMAIPFFIAAGVFMGAGGLSRRLLNLADEMLGALPGGMALATIGTCMFFAAIS
GSGPATVAAIGSLTIPAMVERGYCKYFSAAIVAAAGAIGVMIPPSNPFVVYGVSAQASIGKLFMGGIVPGLLTGLALMAY
SYWYSKKRGWKGEVRDRNLKTFMHAVWEAKWALMVPVIVLGGIYGGIMTPTEAAALAAFYGLIIGCFVHRELSCGSFYDC
VVEAAGTSAMVIVLMSMATIFGNIMTIEEVPTTIAQAMLGLTTDKIAILLMINVLLLIIGTFMEALAAIVILTPILLPIV
LKVGVDPVHFGIIMVVNLAIGFVTPPVGVNLFVASGVANAKIEQLSKVVLPLIALMLAVLLITTYVPAIPMFFAG
>Mature_634_residues
SDPNVTATIMNAQGECSSGSLESRPGILGWLDANFEKPFLVAGMLAIIFIITFQTLYRYIGVYLHEGAAAAVWTEEMARF
IFIWISYLAVPVAIKNRSSIRVDIIFDRLPVRFQNISWIIVDVCFLTLAATVLWQSLDLIKMQLTYPQTSPALQLPYYIP
YLVLPVSFGLMAVRLLQDLAGQVRICGAADTVIGLILCAVLAAPLFIADYIDPLPVLFGYFALFLVVGVPIAIGLGLAAL
ATIVAAGSLPIDYVAQIAFTSIDSFPIMAIPFFIAAGVFMGAGGLSRRLLNLADEMLGALPGGMALATIGTCMFFAAISG
SGPATVAAIGSLTIPAMVERGYCKYFSAAIVAAAGAIGVMIPPSNPFVVYGVSAQASIGKLFMGGIVPGLLTGLALMAYS
YWYSKKRGWKGEVRDRNLKTFMHAVWEAKWALMVPVIVLGGIYGGIMTPTEAAALAAFYGLIIGCFVHRELSCGSFYDCV
VEAAGTSAMVIVLMSMATIFGNIMTIEEVPTTIAQAMLGLTTDKIAILLMINVLLLIIGTFMEALAAIVILTPILLPIVL
KVGVDPVHFGIIMVVNLAIGFVTPPVGVNLFVASGVANAKIEQLSKVVLPLIALMLAVLLITTYVPAIPMFFAG

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=400, Percent_Identity=35.25, Blast_Score=230, Evalue=3e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 67560; Mature: 67429

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPNVTATIMNAQGECSSGSLESRPGILGWLDANFEKPFLVAGMLAIIFIITFQTLYRY
CCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
IGVYLHEGAAAAVWTEEMARFIFIWISYLAVPVAIKNRSSIRVDIIFDRLPVRFQNISWI
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEECCCHHH
IVDVCFLTLAATVLWQSLDLIKMQLTYPQTSPALQLPYYIPYLVLPVSFGLMAVRLLQDL
HHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHH
AGQVRICGAADTVIGLILCAVLAAPLFIADYIDPLPVLFGYFALFLVVGVPIAIGLGLAA
CCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LATIVAAGSLPIDYVAQIAFTSIDSFPIMAIPFFIAAGVFMGAGGLSRRLLNLADEMLGA
HHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LPGGMALATIGTCMFFAAISGSGPATVAAIGSLTIPAMVERGYCKYFSAAIVAAAGAIGV
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
MIPPSNPFVVYGVSAQASIGKLFMGGIVPGLLTGLALMAYSYWYSKKRGWKGEVRDRNLK
EECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
TFMHAVWEAKWALMVPVIVLGGIYGGIMTPTEAAALAAFYGLIIGCFVHRELSCGSFYDC
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
VVEAAGTSAMVIVLMSMATIFGNIMTIEEVPTTIAQAMLGLTTDKIAILLMINVLLLIIG
HHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
TFMEALAAIVILTPILLPIVLKVGVDPVHFGIIMVVNLAIGFVTPPVGVNLFVASGVANA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHH
KIEQLSKVVLPLIALMLAVLLITTYVPAIPMFFAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDPNVTATIMNAQGECSSGSLESRPGILGWLDANFEKPFLVAGMLAIIFIITFQTLYRY
CCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
IGVYLHEGAAAAVWTEEMARFIFIWISYLAVPVAIKNRSSIRVDIIFDRLPVRFQNISWI
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEECCCHHH
IVDVCFLTLAATVLWQSLDLIKMQLTYPQTSPALQLPYYIPYLVLPVSFGLMAVRLLQDL
HHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHH
AGQVRICGAADTVIGLILCAVLAAPLFIADYIDPLPVLFGYFALFLVVGVPIAIGLGLAA
CCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LATIVAAGSLPIDYVAQIAFTSIDSFPIMAIPFFIAAGVFMGAGGLSRRLLNLADEMLGA
HHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LPGGMALATIGTCMFFAAISGSGPATVAAIGSLTIPAMVERGYCKYFSAAIVAAAGAIGV
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
MIPPSNPFVVYGVSAQASIGKLFMGGIVPGLLTGLALMAYSYWYSKKRGWKGEVRDRNLK
EECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
TFMHAVWEAKWALMVPVIVLGGIYGGIMTPTEAAALAAFYGLIIGCFVHRELSCGSFYDC
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
VVEAAGTSAMVIVLMSMATIFGNIMTIEEVPTTIAQAMLGLTTDKIAILLMINVLLLIIG
HHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
TFMEALAAIVILTPILLPIVLKVGVDPVHFGIIMVVNLAIGFVTPPVGVNLFVASGVANA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHH
KIEQLSKVVLPLIALMLAVLLITTYVPAIPMFFAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]